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How To Avoid China ’ s Medicine Monopoly
I want to share a shocking statistic with you…
Around 80% of all the pharmaceuticals sold in America — both prescription and over-the-counter — are manufactured in China.
I’m talking about drugs for Parkinson’s and Alzheimer’s, blood pressure and blood thinners, diuretics, aspirin, antibiotics, and a big chunk of the world’s insulin and diabetes drugs — just to name a few.1
We don’t even make penicillin anymore. The last penicillin plant in the U.S. closed its doors in 2004.
Americans who rely on medicine are now almost entirely at the mercy of a country whose relations with the U.S. have become more ...
Source: Al Sears, MD Natural Remedies - September 19, 2023 Category: Complementary Medicine Authors: Jacob Tags: Health Source Type: news
This Overlooked Nutrient May Be The Key To Brain Power
Aging is inevitable. But have you noticed that some very elderly people still don’t miss a thing?
Some of my patients fall into this category. I’ve worked with many centenarians who remain quick-witted, with keen memories and focus.
You can be one of these people, too — an all-star senior…
Inside all of you, your cells are constantly busy dividing up to two trillion times per day. The new cells replace old, damaged, or dead cells and help you live, grow and thrive.
Human cell lines have built-in mortality. As your cells divide, there’s a limit at which their limit is reached.
There’s an internal mechanism o...
Source: Al Sears, MD Natural Remedies - August 25, 2023 Category: Complementary Medicine Authors: Jacob Tags: Brain Health Source Type: news
Complementary methods in the treatment of complex regional pain syndrome
CONCLUSIONS: Integrative, complementary medical therapy options support the CRPS patient in coping with their disease and the related pain. These options can play an important role in the multimodal, interdisciplinary treatment of this disease.PMID:37268791 | DOI:10.1007/s00482-023-00724-7
Source: Schmerz - June 2, 2023 Category: Anesthesiology Authors: T Gabriel P Klose Source Type: research
Comprehensive analysis of the diagnostic and therapeutic value of the hypoxia-related gene PLAUR in the progression of atherosclerosis
In this study, Plasminogen activator, urokinase receptor (PLAUR) was identified as an effective diagnostic marker for AS lesion progression by combining WGCNA and random forest algorithm. We validated the stability of the diagnostic value on multiple external datasets including humans and mice. We identified a significant correlation between PLAUR expression and lesion progression. We mined multiple single cell-RNA sequencing (sc-RNA seq) data to nominate macrophage as the key cell cluster for PLAUR mediated lesion progression. We combined cross-validation results from multiple databases to predict that HCG17-hsa-miR-424-5...
Source: Atherosclerosis - May 26, 2023 Category: Cardiology Authors: Chengyi Dai Yuhang Lin Source Type: research
Transcriptomic analysis reveals the potential biological mechanism of AIS and lung adenocarcinoma
DiscussionOur findings suggest that the hub genes we found in this study contribute to the development and progression of AIS and LUAD by altering the cellular senescence pathway. Thus, they may be promising markers for diagnosis and prognosis.
Source: Frontiers in Neurology - May 17, 2023 Category: Neurology Source Type: research
Human umbilical cord-derived mesenchymal stem cell transplantation supplemented with curcumin improves the outcomes of ischemic stroke via AKT/GSK-3 β/β-TrCP/Nrf2 axis
Human umbilical cord-derived mesenchymal stem cell (hUC-MSC) engraftment is a promising therapy for acute ischemic stroke (AIS). However, the harsh ischemic microenvironment limits the therapeutic efficacy of ...
Source: Journal of Neuroinflammation - February 24, 2023 Category: Neurology Authors: Yuan Li, Jialu Huang, Jie Wang, Simin Xia, Hong Ran, Lenyu Gao, Chengjian Feng, Li Gui, Zhenhua Zhou and Jichao Yuan Tags: Research Source Type: research
Curcumin ’s mechanism of action against ischemic stroke: A network pharmacology and molecular dynamics study
In conclusion, curcumin affects multiple targets and pathways to inhibit various important pathogenic mechanisms of IS, including oxidative stress, neuronal death, and inflammatory responses. This study offers fresh perspectives on the transformation of curcumin to clinical sett ings and the development of IS therapeutic agents.
Source: PLoS One - January 4, 2023 Category: Biomedical Science Authors: Yangyang Wang Source Type: research
Novel multifunctional bionanoparticles modified with sialic acid for stroke treatment
Int J Biol Macromol. 2022 Jun 15:S0141-8130(22)01306-X. doi: 10.1016/j.ijbiomac.2022.06.102. Online ahead of print.ABSTRACTOxidative stress and inflammation are two key pathophysiological mechanisms that lead to neuronal apoptosis and brain damage following ischemia/reperfusion (I/R) injury. Because of their complex pathological mechanisms and the presence of the blood-brain barrier, the treatment of I/R is severely limited. Inspired by the fact that Macrophage membranes (MM) can cross the blood-brain barrier, we have developed a new multifunctional bionic particle (MSAOR@Cur). The modification of Sialic acid (SA) on the s...
Source: Cell Research - June 18, 2022 Category: Cytology Authors: Yanguo Su Chunjing Guo Qiang Chen Huimin Guo Jinqiu Wang Mu Kaihang Daquan Chen Source Type: research
Curcumin Restrains Oxidative Stress of After Intracerebral Hemorrhage in Rat by Activating the Nrf2/HO-1 Pathway
Intracerebral hemorrhage (ICH), a severe hemorrhagic stroke, induces cerebral oxidative stress and severe secondary neurological injury. Curcumin was demonstrated to inhibit oxidative stress in the brain after ICH. However, the pharmacological mechanism needs further research. We used an intrastriatal injection of autologous blood to make the rat ICH model, and then the rat was treated with curcumin (100 mg/kg/day). Modified Neurological Severity Score (mNSS) and corner test results showed that curcumin could significantly promote the neurological recovery of ICH rats. Meanwhile, curcumin could substantially reduce ROS an...
Source: Frontiers in Pharmacology - April 27, 2022 Category: Drugs & Pharmacology Source Type: research
Benefits of Curcumin in the Vasculature: A Therapeutic Candidate for Vascular Remodeling in Arterial Hypertension and Pulmonary Arterial Hypertension?
Growing evidence suggests that hypertension is one of the leading causes of cardiovascular morbidity and mortality since uncontrolled high blood pressure increases the risk of myocardial infarction, aortic dissection, hemorrhagic stroke, and chronic kidney disease. Impaired vascular homeostasis plays a critical role in the development of hypertension-induced vascular remodeling. Abnormal behaviors of vascular cells are not only a pathological hallmark of hypertensive vascular remodeling, but also an important pathological basis for maintaining reduced vascular compliance in hypertension. Targeting vascular remodeling repre...
Source: Frontiers in Physiology - April 1, 2022 Category: Physiology Source Type: research
Immunomodulatory Therapeutic Effects of Curcumin on M1 / M2 Macrophage polarization in Inflammatory Diseases
CONCLUSION: Curcumin not only enhances anti- tumor immunity (via shifting M polarization towards to M1 phenotype and/or up-regulation of M1 markers expression), but ameliorates inflammatory diseases including auto immune diseases (experimental autoimmune myocarditis and Behcet's disease), nephropathy, chronic serum sickness, stroke and atherosclerosis.PMID:35331128 | DOI:10.2174/1874467215666220324114624
Source: Atherosclerosis - March 25, 2022 Category: Cardiology Authors: Elham Abdollahi Thomas P Johnston Zahra Ghaneifar Parviz Vahedi Pouya Goleij Sara Azhdari Abbas Shapouri Moghaddam Source Type: research
