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Nutrition: Calcium

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Total 29 results found since Jan 2013.

Ella’s story: Two rare diseases and the NICU roller coaster ride
“Everyone tells you that the NICU is a roller coaster ride. What they don’t tell you is that it’s a customized roller coaster ride just for you. You never know what’s coming at you next,” says Carrie Shea, whose daughter Ella spent her first three months of life in Boston Children’s Hospital NICU. Today, Ella is a “remarkably normal little girl,” says Carrie. It’s quite a feat for the three-year-old who was born with GACI (generalized arterial calcification of infancy), an extremely rare condition with an 85 percent mortality rate, and diagnosed with PKU (phenylketonuria), a second rare genetic disorder, ...
Source: Thrive, Children's Hospital Boston - March 5, 2015 Category: Pediatrics Authors: Lisa Fratt Tags: Our patients’ stories Source Type: news

The Need for a Rational Approach to Vasoconstrictive Syndromes: Transcranial Doppler and Calcium Channel Blockade in Reversible Cerebral Vasoconstriction Syndrome
Conclusion: Though small, our cohort demonstrates potential utility of TCD to monitor RCVS, and relative superiority of extended-release verapamil over other calcium channel blockers, illustrating the need for larger randomized trials. Case Rep Neurol 2016;8:161 –171
Source: Case Reports in Neurology - July 29, 2016 Category: Neurology Source Type: research

Association of Subjective and Objective Sleep Duration as well as Sleep Quality with Non-Invasive Markers of Sub-Clinical Cardiovascular Disease (CVD): A Systematic Review.
CONCLUSIONS: Overall, our review provided mixed results, which is generally in line with published literature, with most of the studies showing a significant relationship with subclinical CVD, but only some studies failed to demonstrate such an association. Although such mechanistic relationship needs further evaluation in order to determine appropriate screening strategies in vulnerable populations, this review strongly suggested the existence of a relationship between abnormal sleep duration and quality with increased subclinical CVD burden. PMID: 27840384 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - November 16, 2016 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Cardiometabolic response of juvenile rainbow trout exposed to dietary selenomethionine
Publication date: Available online 8 March 2018 Source:Aquatic Toxicology Author(s): Connor M. Pettem, Jennifer M. Briens, David M. Janz, Lynn P. Weber Selenium (Se) is considered as an essential trace element, involved in important physiological and metabolic functions for all vertebrate species. Fish require dietary concentrations of 0.1 to 0.5 μg Se/g dry mass (d.m.) to maintain normal physiological and selenoprotein function, however concentrations exceeding 3 μg/g d.m. have been shown to cause toxicity. As Se is reported to have a narrow margin between essentiality and toxicity, there is growing concern surroun...
Source: Aquatic Toxicology - March 9, 2018 Category: Toxicology Source Type: research

Cardiometabolic response of juvenile rainbow trout exposed to dietary selenomethionine.
Abstract Selenium (Se) is considered an essential trace element, involved in important physiological and metabolic functions for all vertebrate species. Fish require dietary concentrations of 0.1-0.5 μg Se/g dry mass (d.m.) to maintain normal physiological and selenoprotein function, however concentrations exceeding 3 μg/g d.m. have been shown to cause toxicity. As Se is reported to have a narrow margin between essentiality and toxicity, there is growing concern surrounding the adverse effects of elevated Se exposure caused by anthropogenic activities. Previous studies have reported that elevated dietary exp...
Source: Aquatic Toxicology - March 8, 2018 Category: Toxicology Authors: Pettem CM, Briens JM, Janz DM, Weber LP Tags: Aquat Toxicol Source Type: research

Another Chance for Medtronic ’s Renal Denervation Therapy
Medtronic has yet another chance to prove its renal denervation therapy can treat uncontrolled hypertension. The Dublin-based company has received FDA approval to begin a clinical trial to evaluate the Symplicity Spyral renal denervation system with patients on medication for high blood pressure. The ON MED Trial is a 2:1 randomized, sham-controlled study and will randomize up to 340 patients at 55 centers in the U.S., Japan, Europe, Australia and Canada. Patients will be followed out to three years. Primary safety endpoints will include major adverse events at one month and new renal artery stenosis at six months. The pri...
Source: MDDI - November 8, 2018 Category: Medical Devices Authors: Omar Ford Tags: Business Source Type: news

Virtual histology-intravascular ultrasound as a diagnostic alternative for morphological characterization of carotid plaque: comparison with histology and high-resolution magnetic resonance findings
Conclusion We believe that VH-IVUS may be useful when a quick intraprocedural evaluation of a carotid plaque before or after stent placement is required, but is not suitable for the accurate in-vivo differentiation between stable and unstable plaques prone to rupture, due to the suboptimal assessment of the necrotic component, fibrous cap thickness and rupture signs. We do believe, however, that these results need further evaluation in larger populations to be confirmed.
Source: Journal of Cardiovascular Medicine - April 2, 2019 Category: Cardiology Tags: Research articles: Coronary artery disease Source Type: research

Pre-anesthetic ultrasonographic assessment of the internal jugular vein for prediction of hypotension during the induction of general anesthesia
ConclusionIJV-A in the Trendelenburg position was an independent predictor of hypotension during induction. Further study is required to examine the diagnostic accuracy of IJV-A as a predictor for hypotension during induction.
Source: Journal of Anesthesia - August 25, 2019 Category: Anesthesiology Source Type: research

Ultrasound-based internal carotid artery plaque characterization using deep learning paradigm on a supercomputer: a cardiovascular disease/stroke risk assessment system
AbstractVisual or manual characterization and classification of atherosclerotic plaque lesions are tedious, error-prone, and time-consuming. The purpose of this study is to develop and design an automated carotid plaque characterization and classification system into binary classes, namely symptomatic and asymptomatic types via the deep learning (DL) framework implemented on a supercomputer. We hypothesize that on ultrasound images, symptomatic carotid plaques have (a) a low grayscale median because of a histologically large lipid core and relatively little collagen and calcium, and (b) a higher chaotic (heterogeneous) gra...
Source: The International Journal of Cardiovascular Imaging - January 9, 2021 Category: Radiology Source Type: research

The Prognostic Value of a Validated and Automated Intravascular Ultrasound-Derived Calcium Score
ConclusionsThe ICS, calculated by a validated automated algorithm derived from routine IVUS pullbacks, was strongly associated with the long-term risk of POCE.Graphical abstract
Source: Journal of Cardiovascular Translational Research - February 23, 2021 Category: Cardiology Source Type: research

Rationale and design of the Brazilian Diabetes Study: a prospective cohort of type 2 diabetes
CONCLUSION: The BDS will be the first large population-based cohort dedicated to the identification of clinical phenotypes of T2D at higher risk of cardiovascular events. Data derived from this study will provide valuable information on risk estimation and prevention of cardiovascular and other diabetes-related events.PMID:35174749 | DOI:10.1080/03007995.2022.2043658
Source: Atherosclerosis - February 17, 2022 Category: Cardiology Authors: Joaquim Barreto Vaneza Wolf Isabella Bonilha Beatriz Luchiari Marcus Lima Alessandra Oliveira Sofia Vitte Gabriela Machado Jessica Cunha Cynthia Borges Daniel Munhoz Vicente Fernandes Sheila Tatsumi Kimura-Medorima Ikaro Breder Marta Duran Fernandez Thiag Source Type: research