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Letter to Editor on “Lacunar Stroke in Cryptococcal Meningitis: Clinical and Radiographic Features”
We read with much pleasure the article “Lacunar Stroke in Cryptococcal Meningitis: Clinical and Radiographic Features” by Vela et al published in the Journal of Stroke and Cerebrovascular Disease.1 Authors have done a commendable job at describing the clinical and radiographical details of stroke in a cohort of patients with cryptoco ccal meningitis. Authors have collected extensive data over 18years from the University of Colorado Hospital, and have identified 42 patients. Among these, 32 (76%) of the patients had available neuroimaging.
Source: Journal of Stroke and Cerebrovascular Diseases - March 14, 2019 Category: Neurology Authors: Ajay K. Mishra, Anu A. George, Kamal K. Sahu, Amos Lal, Cijoy K. Kuriakose Tags: Letter to the Editor Source Type: research

Stroke in patients with tuberculous meningitis in a low TB endemic country: an increasing medical emergency?
This study evaluated the frequency, clinical characteristics, risk factors and outcomes of patients with TBM complicated by stroke admitted to the Infectious Disease Clinic, University of Perugia Hospital, Italy from 1971 to 2010. Over four decades, 419 patients were admitted with tuberculosis, of these 30 (7.1%) were diagnosed with TBM: 20 definite, one probable and nine possible. Twenty-six were evaluable for stroke and six (23%) had stroke. The latter six had advanced stages of meningitis, two tested HIV positive, three HIV negative and in one HIV was not performed. Of seven patients without stroke tested for HIV, only ...
Source: New Microbiologica - December 1, 2014 Category: Microbiology Tags: New Microbiol Source Type: research

Stroke in paediatric pneumococcal meningitis: a cross-sectional population-based study
Before routine infant pneumococcal immunisation and improved access to neuroimaging, around 25% of children with pneumococcal meningitis (PM) suffered ischaemic stroke (IS).1 2 In a population-based retrospective audit (UHS ZAUD2053), we investigated the postimmunisation prevalence of stroke/cerebrovascular disease (CVD), and compared features of children with and without IS/CVD. We included all cases of PM in children <18 years old with a Wessex postcode admitted to our tertiary centre, University Hospital Southampton (UHS) and the eight hospitals in our referral catchment area of Hampshire and Dorset (2001 childh...
Source: Archives of Disease in Childhood - July 11, 2013 Category: Pediatrics Authors: Pryde, K., Walker, W. T., Hollingsworth, C., Haywood, P., Baird, J., Hussey, M., Freeman, A., Gawne-Cain, M., Harms, B., Kirkham, F. J., Faust, S. N. Tags: PostScript Source Type: research

Antithrombotic therapy for secondary stroke prevention in meningitis
In this issue of The Journal, Boelman et al present a 15-year retrospective cohort experience of management and follow-up of 22 patients with stroke complicating bacterial meningitis cared for at the Hospital for Sick Children, Toronto, and the British Columbia Children's Hospital, Vancouver.
Source: The Journal of Pediatrics - September 25, 2014 Category: Pediatrics Authors: Sarah S. Long Tags: The Editors' Perspectives Source Type: research

The Case Files: Unusual Headache
By Al-Hashimi, Siddhartha DO; Leavens, John MD A 23-year-old woman with a history of migraine headaches presented to the emergency department for a different-than-usual headache. She had a six-day history of intermittent headaches. The onset was at rest, and there was no history of trauma.   The headache was located behind her left eye, and it radiated into the posterior portion of her head. She characterized it as being 8/10 in intensity. Bright lights were reported as an exacerbating factor. The headache was associated with nausea and multiple episodes of emesis. She had 10 episodes of vomiting the evening prior to arri...
Source: The Case Files - June 5, 2014 Category: Emergency Medicine Tags: Blog Posts Source Type: research

Severe Symptoms, but a Truly Treatable Disease
​BY NOURA MAHDI; DARRON LEWIS; JEREMY OSBORNE; & AHMED RAZIUDDIN, MDA 73-year-old man was brought to the emergency department from his nursing home for rectal bleeding and anemia. The patient mentioned he had had episodes of bright red rectal bleeding and constipation for a few months. A colonoscopy had been done prior to the visit, which revealed a large intestine tumor and biopsy confirming adenocarcinoma. He was awaiting an appointment with his surgeon.The patient reported bloody rectal leakage, and a CBC done at the nursing home showed a hemoglobin level of 7.2. He also complained of dyspnea but denied any other ...
Source: The Case Files - March 20, 2018 Category: Emergency Medicine Tags: Blog Posts Source Type: research

Trends in Age of Cochlear Implant Recipients, and the Impact on Perioperative Complication Rates
Objective: The aim of the study is to examine trends in the age of patients receiving cochlear implants and to determine the effect of age on the rate of perioperative complications. Study Design: Retrospective analysis of deidentified administrative claims data from a US commercial insurance database (Optum). Patients: Individuals undergoing cochlear implantation between 2003 and 2016. Setting: US hospital and outpatient facilities serving commercially insured patients. Intervention: Cochlear implantation. Main Outcome Measures: Age at implantation, incidence of perioperative complications within 30 days ...
Source: Otology and Neurotology - March 17, 2020 Category: ENT & OMF Tags: COCHLEAR IMPLANTS Source Type: research

266 A drowsy patient: beyond the familiar territory
A 72-year-old man was brought to the hospital after he was found unresponsive at home by his wife who reported that he has been sleepy in the last few days. He has a background of hypertension, myocardial infarct, and osteoarthritis. His medications include anti-hypertensive and morphine sulphate. On examination, he was drowsy with GCS fluctuating between 9–11 but maintaining his airways. He was moving all four limbs; pupils were small and unequal but reactive to light. Planter reflexes were downgoing. Opioid toxicity was suspected and treated with naloxone without any response. The CT head scan showed no acute patho...
Source: Journal of Neurology, Neurosurgery and Psychiatry - May 27, 2022 Category: Neurosurgery Authors: Oo, A., Khine, N. Tags: Poster Presentations Source Type: research

What Causes Ataxia?
Discussion Coordination and balance problems are caused by various problems affecting the central and peripheral nervous system. Normal development of a child or weakness of a child are commonly mistaken for true ataxia. Ataxia specifically refers to “…impairment of the coordination of movement without loss of muscle strength.” If it is purely due to abnormalities of the cerebellum then there should be no changes in mental status, sensation or weakness. Sometimes it is difficult to determine if there are abnormalities in other areas. For example, Guillian-Barre often presents with difficulty or clumsy wal...
Source: PediatricEducation.org - March 31, 2014 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Boston Children’s Hospital Testing Epileptic Seizure-Detecting Watch
BOSTON (CBS) – Epilepsy is a tough condition to live with and, despite treatment, many patients often still have seizures. But now there’s a new way to warn their families when there is trouble. Leonor Colon’s 12-year-old son, Gali, has suffered from seizures all his life after having a stroke at birth. Even on multiple medications, he still has a seizure a week, usually at night. “My biggest fear is that if I’m not here to help him, that when I wake him up, he will be dead from seizures,” she told WBZ-TV. It’s a scary but real possibility. Dr. Tobi Loddenkemper, an epilepsy specialist at Bost...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - December 16, 2014 Category: Consumer Health News Authors: miketoole Tags: Health Local News Seen On WBZ-TV Syndicated Local Watch Listen Boston Children's Hospital CBS Boston Dr. Mallika Marshall Dr. Tobias Loddenkemper Embrace Epilepsy Leonor Colon Seizure Watch Source Type: news

Madison Small And The Threat Of Bacterial Meningitis
Eighteen-year old high school student Madison Small of Ashburn, Virginia is dead after a swift and unexpected bacterial infection, reported ABC News. Small, an accomplished softball player, complained of a headache on the evening of Monday, Apr. 6 and was taken to the hospital, according to local news station WJLA in the video above. She died the next morning. On April 13, health investigators announced that she had died of bacterial meningitis, but said that her case was not part of a wider outbreak in the community. Bacterial meningitis is rare but severe. The infection, which can be caused by several different strai...
Source: Science - The Huffington Post - April 13, 2015 Category: Science Source Type: news

Cortical laminar necrosis due to refractory status epilepticus in a kidney transplant patient with cryptococcal meningitis
Publication date: Available online 17 November 2015 Source:Indian Journal of Transplantation Author(s): Zaheer Virani, Prashant Rajput, Pankaj Agarwal, Rashmi Badhe A 56-year-old diabetic male underwent kidney transplant in 2010. He was brought to the hospital with complaints of vomiting and altered sensorium of 10 days duration. Lumbar puncture revealed cryptococcal meningitis. He was promptly initiated on liposomal amphotericin B and flucytosine. Immunosuppressive agents tacrolimus and mycophenolate mofetil were discontinued. There was an initial improvement in his sensorium but a few days later, he developed super...
Source: Indian Journal of Transplantation - November 17, 2015 Category: Transplant Surgery Source Type: research

Valacyclovir and Acyclovir Neurotoxicity With Status Epilepticus
We present the case of a 52-year-old man with hypertension, diastolic congestive heart failure, end-stage renal disease on hemodialysis 3 times a week and a remote history of a hemorrhagic stroke who presented to the emergency department with a vesicular rash on his left arm. The rash was observed to be in a dermatomal distribution, and a diagnosis of herpes zoster was made. The patient was discharged home on valacyclovir 1 g 3 times a day for a duration of 7 days. The patient took 2 doses of valacyclovir before presenting to the hospital again with irritability and hallucinations. Over the next several days, the patient's...
Source: American Journal of Therapeutics - January 1, 2016 Category: Drugs & Pharmacology Tags: Case Reports Source Type: research

Tuberculosis Made Me Blind, But We Can Make Sure No One Else Needs to Suffer Like I Did
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Source: Healthy Living - The Huffington Post - March 24, 2016 Category: Consumer Health News Source Type: news

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