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Infectious Disease: Influenza

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Total 22100 results found since Jan 2013.

Salmonella delivers H9N2 influenza virus antigens via a prokaryotic and eukaryotic dual-expression vector and elicits bivalent protection against avian influenza and fowl typhoid
Dev Comp Immunol. 2023 Sep 13:105058. doi: 10.1016/j.dci.2023.105058. Online ahead of print.ABSTRACTThe H9N2 avian influenza virus significantly affects the health of poultry and humans. We identified a prokaryotic and eukaryotic dual-expression vector system, pJHL270, that can provide simultaneous MHC class I and II stimulation of the host immune system, and we designed vaccine antigens by selecting the consensus HA1 sequence and M2e antigens from H9N2 virus circulating in South Korea from 2000 to 2021. The genes were cloned into the pJHL270 vector, and the cloned plasmid was delivered by a live-attenuated Salmonella Gall...
Source: Developmental and Comparative Immunology - September 15, 2023 Category: Allergy & Immunology Authors: Chamith Hewawaduge Jun Kwon Chandran Sivasankar Ji-Young Park Amal Senevirathne John Hwa Lee Source Type: research

Association of vaccine-specific regulatory T cells with reduced antibody response to repeated influenza vaccination
This article is protected by copyright. All rights reserved.PMID:37713727 | DOI:10.1002/eji.202350525
Source: European Journal of Immunology - September 15, 2023 Category: Allergy & Immunology Authors: Pin-Hung Lin Po-Ju Hsiao Ching-Fu Pan Ming-Tsan Liu Jann-Tay Wang Chi Ching Fang-Yi Wu Yi-Hsuan Lin Yu-Chan Yang Le-Yin Hsu Hung-Chih Yang Un-In Wu Source Type: research

Mentha pulegium: A Plant With Several Medicinal Properties
Endocr Metab Immune Disord Drug Targets. 2023 Sep 14. doi: 10.2174/1871530323666230914103731. Online ahead of print.ABSTRACTThe species Mentha pulegium L. (M. pulegium L.) belongs to the family Lamiaceae, native to Europe, North Africa, and the Middle East, and the genus Mentha. It has been traditionally used in food, cosmetics, and medicines. It is a perennial, fragrant, well-liked, herbaceous plant that can grow up to half a meter tall. It is extensively used as a food flavoring, particularly for Moroccan traditional drinks. Chewing mint and M. pulegium, a relaxing and refreshing plant, can be used to treat hiccups and a...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - September 15, 2023 Category: Endocrinology Authors: Smail Amtaghri Miloudia Slaoui Mohamed Eddouks Source Type: research

Methods for virus recovery from environmental surfaces to monitor infectious viral contamination
Environ Int. 2023 Sep 9;180:108199. doi: 10.1016/j.envint.2023.108199. Online ahead of print.ABSTRACTAccurate quantification of infectious contaminants on environmental surfaces, particularly infectious viruses, is essential for contact transmission risk assessment; however, difficulties in recovering viruses from surfaces using swabs complicates this quantification process. Herein, we identified the factors that significantly affected virus recovery rates and developed an ideal swab method that yielded the highest rate of virus recovery. We comprehensively analyzed the effects of swab type (cotton/polyester), swab water c...
Source: Environment International - September 15, 2023 Category: Environmental Health Authors: Hajime Miyazaki Ryohei Hirose Mikako Ichikawa Hiroki Mukai Katsuma Yamauchi Takaaki Nakaya Yoshito Itoh Source Type: research

The long-term safety and tolerability of anifrolumab for patients with systemic lupus erythematosus in Japan: TULIP-LTE subgroup analysis
CONCLUSIONS: Anifrolumab 300 mg showed a favourable benefit-risk profile for the long-term treatment of adult patients with moderate to severe SLE from Japan, with safety, tolerability, and efficacy profiles consistent with the overall population.PMID:37706527 | DOI:10.1093/mr/road092
Source: Herpes - September 14, 2023 Category: Infectious Diseases Authors: Yoshiya Tanaka Tatsuya Atsumi Masato Okada Tomoya Miyamura Tomonori Ishii Susumu Nishiyama Ryutaro Matsumura Atsushi Kawakami Nobuya Hayashi Gabriel Abreu Sule Yavuz Catharina Lindholm Hussein Al-Mossawi Tsutomu Takeuchi Source Type: research

Interim Effectiveness Estimates of 2023 Southern Hemisphere Influenza Vaccines in Preventing Influenza-Associated Hospitalizations - REVELAC-i Network, March-July 2023
MMWR Morb Mortal Wkly Rep. 2023 Sep 15;72(37):1010-1015. doi: 10.15585/mmwr.mm7237e1.NO ABSTRACTPMID:37708084 | DOI:10.15585/mmwr.mm7237e1
Source: MMWR Morb Mortal Wkl... - September 14, 2023 Category: Epidemiology Authors: Ashley L Fowlkes Francisco Nogareda Annette Regan Sergio Loayza Jose Mendez Mancio Lindsey M Duca Paula Couto Juliana Leite Angel Rodriguez Daniel Salas Eduardo Azziz-Baumgartner REVELAC –i Network Source Type: research

Wastewater Surveillance Data as a Complement to Emergency Department Visit Data for Tracking Incidence of Influenza A and Respiratory Syncytial Virus - Wisconsin, August 2022-March 2023
MMWR Morb Mortal Wkly Rep. 2023 Sep 15;72(37):1005-1009. doi: 10.15585/mmwr.mm7237a2.ABSTRACTWastewater surveillance has been used to assist public health authorities in tracking local transmission of SARS-CoV-2. The usefulness of wastewater surveillance to track community spread of other respiratory pathogens, including influenza virus and respiratory syncytial virus (RSV), is less clear. During the 2022-23 respiratory diseases season, concentrations of influenza A virus and RSV in wastewater samples in three major Wisconsin cities were compared with emergency department (ED) visits associated with these pathogens. In all...
Source: MMWR Morb Mortal Wkl... - September 14, 2023 Category: Epidemiology Authors: Peter M DeJonge Carly Adams Ian Pray Melissa K Schussman Rebecca B Fahney Martin Shafer Dagmara S Antkiewicz Ad élaïde Roguet Source Type: research

The re-emergence of influenza following the COVID-19 pandemic in Victoria, Australia, 2021 to 2022
ConclusionEnhanced testing for respiratory viruses during the COVID-19 pandemic provided a more complete picture of influenza virus transmission compared with previous seasons. Returned international travellers were important drivers of influenza reemergence, as were young adults, a group whose role has previously been under-recognised in the establishment of seasonal influenza epidemics. Targeting interventions, including vaccination, to these groups could reduce future influenza transmission.PMID:37707981 | DOI:10.2807/1560-7917.ES.2023.28.37.2300118
Source: Euro Surveill - September 14, 2023 Category: Infectious Diseases Authors: Catherine Ga Pendrey Janet Strachan Heidi Peck Ammar Aziz Jean Moselen Rob Moss Md Rezanur Rahaman Ian G Barr Kanta Subbarao Sheena G Sullivan Source Type: research

Nucleic Acid Detection through RNA-Guided Protease Activity in Type III-E CRISPR-Cas Systems
Chembiochem. 2023 Sep 14:e202300401. doi: 10.1002/cbic.202300401. Online ahead of print.ABSTRACTRNA-guided protease activity was recently discovered in the type III-E CRISPR-Cas systems (Craspase), providing a novel platform for engineering a protein probe instead of the commonly used nucleic acid probe in the nucleic acid detection assays. Here, by adapting a fluorescence readout technique using the affinity- and fluorescent protein dual-tagged Csx30 protein substrate, we established an assay monitoring Csx30 cleavage by target ssRNA-activated Craspase. Four Craspase-based nucleic acid detection systems for genes from sev...
Source: Chembiochem - September 14, 2023 Category: Biochemistry Authors: Qiuqiu He Xinlong Lei Yuanjun Liu Xiaoshen Wang Nan Ji Hang Yin Huiping Wang Heng Zhang Guimei Yu Source Type: research

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