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Factors Associated with Antiretroviral Therapy Adherence Among a Community-Based Sample of Sexual Minority Older Adults with HIV
This study utilized a stochastic search variable selection (SVSS) approach to explore potential psychosocial and structural factors associated with HIV-related health outcomes among a community-based sample of older sexual minorities (N = 150) in South Florida, an U.S. HIV-epidemic epicenter. After SVSS, a forward entry regression approach suggested unstable housing, illicit substance use, current nicotine use, and depression were all associated with poorer ART adherence among older sexual minority adults living with HIV. No a ssociations between potential correlates and biological measures of HIV disease severity wer...
Source: AIDS and Behavior - September 23, 2023 Category: Infectious Diseases Source Type: research
PrEPare for Work: A Pilot Randomized Controlled Trial of an Intervention to Optimize HIV PrEP Outcomes Among Male Sex Workers
AbstractHIV pre-exposure prophylaxis (PrEP) use is limited among male sex workers, who are at exceptionally high-risk for HIV infection. We developed a theory-informed, two-pronged intervention ( “PrEPare-for-Work”) to optimize PrEP initiation and adherence among male sex workers, which was preliminarily evaluated in a two-stage pilot randomized controlled trial of 110 male sex workers in the US Northeast. Individuals randomized to the Stage 1 PrEPare-for-Work Case Management arm were th ree times as likely as those in the standard of care (SOC) arm to initiate PrEP (RR = 2.95, 95% CI = 1.57–5.57). Participan...
Source: AIDS and Behavior - September 23, 2023 Category: Infectious Diseases Source Type: research
Diagnostic accuracy of a point-of-care urine tenofovir assay, and associations with HIV viraemia and drug resistance among people receiving dolutegravir and efavirenz-based antiretroviral therapy
CONCLUSIONS: Among PLHIV receiving ART, a rapid urine TFV immunoassay can be used to accurately monitor urine TFV levels compared to the gold standard of LC-MS/MS. Undetectable point-of-care urine TFV results were associated with viraemia, particularly among people receiving dolutegravir.TRIAL REGISTRATION: Pan-African Clinical Trials Registry: PACTR202001785886049.PMID:37735860 | DOI:10.1002/jia2.26172
Source: Journal of the International AIDS Society - September 22, 2023 Category: Infectious Diseases Authors: Jienchi Dorward Richard Lessells Katya Govender Pravi Moodley Natasha Samsunder Yukteshwar Sookrajh Phil Turner Christopher C Butler Gail Hayward Monica Gandhi Paul K Drain Nigel Garrett Source Type: research
Telehealth as an Effective Care Delivery Method During the COVID-19 Pandemic for the Rhode Island Behavioral Health Population
This study investigated (1) if telehealth allowed for patients who seek mental health services to maintain visit frequency and (2) if subpopulations were less likely to utilize telehealth. We used descriptive statistics to analyze the change in total number of visits, in-person visits from pre-waiver to post-waiver, and a multivariate linear regression to identify relationships between demographics and telehealth utilization. Participants were able to maintain the frequency of visits during the COVID-19 pandemic. Race/ethnicity, age, gender, employment status, and housing status were all statistically significant predictor...
Source: Community Mental Health Journal - September 22, 2023 Category: Psychiatry Authors: Demetria Flowers Emily Goodspeed Mackenzie Daly Source Type: research
Kenya: UNFPA-Led Alliance Unveils Financing for Adolescent-Friendly HIV Testing and Treatment
[Capital FM] Nairobi -- Three UN agencies in the country have announced a collaborative effort to promote adolescent-friendly sexual and reproductive health services in a bid to enhance HIV testing and treatment among the youth.
Source: AllAfrica News: Health and Medicine - September 22, 2023 Category: African Health Tags: HIV-Aids and STDs East Africa External Relations Health and Medicine International Organizations and Africa Kenya Source Type: news
Perception of PrEP-Related Stigma in PrEP Users Perception of PrEP-Related Stigma in PrEP Users
This paper provides insight into how PrEP users perceive PrEP-related stigma and identifies the factors associated with this perception.HIV Medicine
Source: Medscape Today Headlines - September 22, 2023 Category: Consumer Health News Tags: HIV/AIDS Journal Article Source Type: news
Possible Role of Dysbiosis of the Gut Microbiome in SLE
AbstractPurpose of ReviewThe resident gut microbiota serves as a double-edged sword that aids the host in multiple ways to preserve a healthy equilibrium and serve as early companions and boosters for the gradual evolution of our immune defensive layers; nevertheless, the perturbation of the symbiotic resident intestinal communities has a profound impact on autoimmunity induction, particularly in systemic lupus erythematosus (SLE). Herein, we seek to critically evaluate the microbiome research in SLE with a focus on intestinal dysbiosis.Recent FindingsSLE is a complex and heterogeneous disorder with self-attack due to loss...
Source: Current Rheumatology Reports - September 22, 2023 Category: Rheumatology Source Type: research
Is cervical dysplasia a major concern in women with inflammatory bowel disease? A Spanish retrospective study
Rev Esp Enferm Dig. 2023 Sep 21. doi: 10.17235/reed.2023.9890/2023. Online ahead of print.ABSTRACTCervical cancer (CC) is the fourth most common cancer affecting women worldwide. The risk of women immunosuppressed due to AIDS or organ transplantation is well documented, as most cases are caused by persistent human papillomavirus (HPV) infection and immunosuppression can prevent clearing HPV. Although European guidelines advise that inflammatory bowel disease (IBD) women under immunosuppression should be screened for CC as regularly as high-risk patients, quality evidence is lacking in our country. We performed a retrospect...
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Lorena Jara Fern ández Juan Ángel Ferrer Jos é Lázaro Pérez Calle Pilar L ópez Serrano Source Type: research
Which Came First, Age-Related Hearing Loss with Tinnitus or Cognitive Impairment? What are the Potential Pathways?
J Integr Neurosci. 2023 Aug 4;22(5):109. doi: 10.31083/j.jin2205109.ABSTRACTResearch on the causal relationship between age-related hearing loss (ARHL) and/or tinnitus and dementia is an important and fast-moving field. In this opinion paper, the up-to-date evidence and potential mechanisms for the bidirectional relationship are reviewed. We also present several critical factors that increase the challenges of understanding the causal relationship. These factors include common causes (such as aging, frailty, vascular impairment, and chronic inflammation), auditory and cognitive reserves, and the difficulty in distinguishin...
Source: Journal of Integrative Neuroscience - September 21, 2023 Category: Neuroscience Authors: Qingwei Ruan Bing Chen Francesco Panza Source Type: research
Women ’s motivations for participating in the dapivirine vaginal ring open label extension study
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Source: AIDS Care - September 21, 2023 Category: Infectious Diseases Authors: Kalendri NaidooElizabeth T. MontgomeryAriana W. K. KatzMorgan GarciaSarita NaidooLeila E. Mansoora Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, South Africab Women ’s Global Health Imperative, Source Type: research
Uganda: MSF Ends Support to HIV Programme in Arua After More Than 20 Years
[MSF] For over 20 years, Médecins Sans Frontières (MSF) has supported the Ministry of Health with treatment for people living with HIV/AIDS in the West Nile region of Uganda and more specifically, in the Arua district.
Source: AllAfrica News: Health and Medicine - September 20, 2023 Category: African Health Tags: Aid and Assistance HIV-Aids and STDs East Africa External Relations Health and Medicine International Organizations and Africa NGOs and Civil Society Uganda Source Type: news
De-novo hematopoiesis from the fetal lung
Blood Adv. 2023 Sep 20:bloodadvances.2022008347. doi: 10.1182/bloodadvances.2022008347. Online ahead of print.ABSTRACTHemogenic endothelial cells (HECs) are specialized cells that undergo endothelial to hematopoietic transition (EHT) to give rise to the earliest precursors of hematopoietic progenitors that will eventually sustain hematopoiesis throughout the lifetime of an organism. Although HECs are thought to be primarily limited to the aorta gonad mesonephros (AGM) during early development, EHT has been described in various other hematopoietic organs and embryonic vessels. Though not defined as a hematopoietic organ, th...
Source: Adv Data - September 20, 2023 Category: Epidemiology Authors: Anthony K Yeung Carlos Villacorta-Martin Jonathan Lindstrom-Vautrin Anna C Belkina Kim Vanuytsel Todd W Dowrey Alexandra B Ysasi Pushpinder Bawa Feiya Wang Vladimir Vrbanac Gustavo Mostoslavsky Alejandro Balazs George J Murphy Source Type: research
Understanding the social and structural context of oral PrEP delivery: an ethnography exploring barriers and facilitators impacting transgender women who engage in street-based sex work in Baltimore, Maryland
AIDS Res Ther. 2023 Sep 20;20(1):69. doi: 10.1186/s12981-023-00556-6.ABSTRACTTransgender women who sell sex (TWSS) experience high rates of HIV acquisition. Antiretrovirals for pre-exposure prophylaxis (PrEP) represent an efficacious HIV prevention strategy. The social and structural factors affecting PrEP delivery amongst TWSS are underexplored in the literature. We conducted ethnographic research to examine how multilevel social and structural factors manifest in TWSS's lived experiences and affect PrEP delivery and use. Twenty-four transgender women were recruited from the SAPPHIRE cohort and completed interviews focuse...
Source: AIDS Research and Therapy - September 20, 2023 Category: Infectious Diseases Authors: Erin E Cooney Katherine H A Footer Jennifer L Glick Anna Passaniti Meridian Howes Susan G Sherman Source Type: research
Barriers and facilitators to implementing advanced HIV disease screening at a secondary referral hospital -Malawi: a convergent parallel study
CONCLUSION: The study has identified major contextual barriers to AHD screening including knowledge gap, poor communication systems and inadequate supporting resources. Improving uptake of AHD screening services would therefore require overcoming the existing barriers by adopting a comprehensive approach in developing barrier-tailored strategies.PMID:37730619 | DOI:10.1186/s12913-023-10009-5
Source: Cell Research - September 20, 2023 Category: Cytology Authors: Brany Mithi Agatha Bula Lester Kapanda Fatsani Ngwalangwa Evanson Z Sambala Source Type: research
