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Total 1428 results found since Jan 2013.

Serum Alkaline Phosphatase Levels and Increased Risk of Brain Hemorrhage in Hemodialysis Patients: The Q-Cohort Study
CONCLUSIONS: Higher serum ALP levels are associated with an increased risk of brain hemorrhage, but not brain infarction, in patients receiving maintenance hemodialysis. High serum ALP level is thus an important risk factor for brain hemorrhage in hemodialysis patients.PMID:34108341 | DOI:10.5551/jat.62885
Source: Journal of Atherosclerosis and Thrombosis - June 10, 2021 Category: Cardiology Authors: Hiromasa Kitamura Shunsuke Yamada Hiroto Hiyamuta Ryusuke Yotsueda Masatomo Taniguchi Masanori Tokumoto Kazuhiko Tsuruya Toshiaki Nakano Takanari Kitazono Source Type: research

Medicare Bundled Payment Policy on Anemia Care, Major Adverse Cardiovascular Events, and Mortality among Adults Undergoing Hemodialysis
CONCLUSIONS: The Medicare reimbursement policy and Food and Drug Administration-recommended erythropoietin-stimulating agent dosing changes were associated with lower erythropoietin-stimulating agent use and lower hemoglobin levels. These changes in anemia care were associated with lower risks of major adverse cardiovascular event, stroke, mortality, and heart failure but higher risk of acute myocardial infarction among adults receiving hemodialysis.PMID:35589388 | DOI:10.2215/CJN.14361121
Source: Clinical Journal of the American Society of Nephrology : CJASN - May 19, 2022 Category: Urology & Nephrology Authors: Haesuk Park Raj Desai Xinyue Liu Steven M Smith Juan Hincapie-Castillo Linda Henry Amie Goodin Saraswathi Gopal Carl J Pepine Raj Mohandas Source Type: research

Anatomic Brain Disease in Hemodialysis Patients: A Cross-sectional Study
Background: Although dialysis patients are at high risk of stroke and have a high burden of cognitive impairment, there are few reports of anatomic brain findings in the hemodialysis population. Using magnetic resonance imaging of the brain, we compared the prevalence of brain abnormalities in hemodialysis patients with that in a control population without known kidney disease. Study Design: Cross-sectional cohort. Setting & Participants: 45 maintenance hemodialysis patients and 67 controls without reported kidney disease, both without history of known stroke. Predictor: The primary predictor was dialysis status. Co...
Source: American Journal of Kidney Diseases - October 5, 2012 Category: Urology & Nephrology Authors: David A. Drew, Rafeeque Bhadelia, Hocine Tighiouart, Vera Novak, Tammy M. Scott, Kristina V. Lou, Kamran Shaffi, Daniel E. Weiner, Mark J. Sarnak Tags: Dialysis Source Type: research

Predictors of Operative Mortality in Cardiac Surgical Patients with Prolonged Intensive Care Unit Duration
Background: Several systems have been developed to predict mortality after intensive care unit (ICU) admission in medical and surgical patients. However, a similar tool specific to cardiac surgical patients with prolonged ICU duration does not exist. The purpose of the current study was to identify independent perioperative predictors of operative mortality among cardiac surgical patients with prolonged ICU duration.Study Design: From 2003 to 2008, a total of 13,105 cardiac surgical patients with ICU durations>48 hours were identified within a statewide database. Perioperative factors, including Society of Thoracic Surgeo...
Source: Journal of the American College of Surgeons - April 24, 2013 Category: Surgery Authors: Damien J. LaPar, Jacob R. Gillen, Ivan K. Crosby, Robert G. Sawyer, Christine L. Lau, Irving L. Kron, Gorav Ailawadi Tags: Original Scientific Articles Source Type: research

Cerebral White Matter Hyperintensity Predicts Cardiovascular Events in Hemodialysis Patients
ConclusionsThe present study indicates that the presence of WMHs is a novel predictor of cardiovascular events in HD patients, and that PVH is more closely associated with incident cardiovascular disease.
Source: Nephrology - June 21, 2013 Category: Urology & Nephrology Authors: Toshihide Naganuma, Yoshiaki Takemoto, Tetsuo Shoji, Hideaki Shima, Eiji Ishimura, Mikio Okamura, Tatsuya Nakatani Tags: Original Article Source Type: research

A 14-year experience with blunt thoracic aortic injury
Conclusions: The incidence of BTAT is low but the mortality associated with it is significant. During the 14-year period studied, there was a clear change in management preference from open repair to endovascular repair at our level 1 trauma center. Outcomes, including stroke, MI, renal failure, paralysis, length of stay, and death, appear to be reduced in the endovascular group.
Source: Journal of Vascular Surgery - June 10, 2013 Category: Surgery Authors: Jennifer Watson, Jeffrey Slaiby, Manuel Garcia Toca, Edward J. Marcaccio, Tze Tec Chong Tags: Clinical research studies Source Type: research

Cerebral white matter hyperintensity predicts cardiovascular events in haemodialysis patients
ConclusionsThe present study indicates that the presence of WMHs is a novel predictor of cardiovascular events in HD patients, and that PVH is more closely associated with incident cardiovascular disease.
Source: Nephrology - September 19, 2013 Category: Urology & Nephrology Authors: Toshihide Naganuma, Yoshiaki Takemoto, Tetsuo Shoji, Hideaki Shima, Eiji Ishimura, Mikio Okamura, Tatsuya Nakatani Tags: Original Article Source Type: research

Cognition may be related to arterial pulsatility index in HD patients.
Conclusion: In well-dialyzed hemodialysis patients with no history of stroke or dementia, CCAPI may correlate with cognitive function and represent a marker for underlying cerebral microvascular disease. PMID: 24780553 [PubMed - in process]
Source: Clinical Nephrology - May 1, 2014 Category: Urology & Nephrology Authors: Post JB, Morin KG, Handrakis JP, Rivera DR, Yen C, Sano M, Spungen AM Tags: Clin Nephrol Source Type: research

Dabigatran and Rivaroxaban Use in Atrial Fibrillation Patients on Hemodialysis.
CONCLUSIONS: -More dialysis patients are being started on dabigatran and rivaroxaban, even when their use is contraindicated and there are no studies to support the benefits outweigh the risks of these drugs in ESRD. PMID: 25595139 [PubMed - as supplied by publisher]
Source: Circulation - January 16, 2015 Category: Cardiology Authors: Chan KE, Edelman ER, Wenger JB, Thadhani RI, Maddux FW Tags: Circulation Source Type: research

Prevalence and correlates of functional dependence among maintenance dialysis patients
Abstract Functional dependence is an important determinant of longevity and quality of life. The purpose of the current study was to determine the prevalence and correlates of functional dependence among patients with end‐stage renal disease (ESRD) receiving maintenance dialysis. We enrolled 148 participants with ESRD from five clinics. Functional status, as measured by basic and instrumental activities of daily living (ADL, IADL), was ascertained by validated questionnaires. Functional dependence was defined as needing assistance in at least one of seven IADLs or at least one of four ADLs. Demographic characteristics, c...
Source: Hemodialysis International - March 2, 2015 Category: Hematology Authors: Niall T. Kavanagh, Brigitte Schiller, Anjali B. Saxena, I‐Chun Thomas, Manjula Kurella Tamura Tags: Original Article Source Type: research

Longer-term Outcomes of Darbepoetin Alfa Versus Epoetin Alfa in Patients With ESRD Initiating Hemodialysis: A Quasi-experimental Cohort Study
Conclusions In incident hemodialysis patients, mortality and cardiovascular event rates did not differ between patients treated at facilities predominantly using DPO versus EPO.
Source: American Journal of Kidney Diseases - May 2, 2015 Category: Urology & Nephrology Source Type: research

A retrospective, longitudinal study estimating the association between interdialytic weight gain and cardiovascular events and death in hemodialysis patients
Conclusions: Greater IDWG is associated with an increased risk of CV morbid events. Strategies that mitigate IDWG may improve CV health and survival among hemodialysis patients.
Source: BMC Nephrology - July 22, 2015 Category: Urology & Nephrology Authors: Claudia CabreraSteven BrunelliDavid RosenbaumEmmanuel AnumKarthik RamakrishnanDonna JensenNils-Olov StålhammarBergur Stefánsson Source Type: research

Coronary artery calcification, cardiovascular events, and death: a prospective cohort study of incident patients on hemodialysis
Conclusions Respondent burden is high for additional testing around the initiation of dialysis. High coronary calcification in patients new to ESRD has a tendency to predict cardiovascular outcomes and death, though effects are attenuated when adjusted for age.
Source: Canadian Journal of Kidney Health and Disease - August 12, 2015 Category: Urology & Nephrology Source Type: research

Outcomes of Chopart Amputation in a Tertiary Referral Diabetic Foot Clinic: Data From a Consecutive Series of 83 Hospitalized Patients
Publication date: Available online 24 November 2015 Source:The Journal of Foot and Ankle Surgery Author(s): Ezio Faglia, Giacomo Clerici, Robert Frykberg, Maurizio Caminiti, Vincenzo Curci, Francesco Cetta, Vincenzo Prisco, Rosaria Greco, Marco Prisco, Alberto Morabito The purpose of the present retrospective study was to evaluate the outcomes (ie, ulcer recurrence, major amputation, death) in diabetic patients undergoing Chopart amputation because of deep infection or gangrene extending to the midfoot. From 2009 to 2011, 83 patients, aged 71.4 ± 9.3 years, underwent a midtarsal amputation and were followed...
Source: The Journal of Foot and Ankle Surgery - November 26, 2015 Category: Orthopaedics Source Type: research