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Total 36 results found since Jan 2013.

Safety of Endovascular Thrombectomy in Patients Receiving Non-Vitamin K Antagonist Oral Anticoagulants Brief Reports
Conclusions— Thrombectomy in non–vitamin K antagonist oral anticoagulant patients seems safe although a comparatively high rate of asymptomatic hemorrhagic transformation was noted. Confirmation in larger prospective controlled cohorts is necessary. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01850797.
Source: Stroke - March 27, 2016 Category: Neurology Authors: Purrucker, J. C., Wolf, M., Haas, K., Rizos, T., Khan, S., Dziewas, R., Kleinschnitz, C., Binder, A., Groschel, K., Hennerici, M. G., Lobotesis, K., Poli, S., Seidel, G., Neumann-Haefelin, T., Ringleb, P. A., Heuschmann, P. U., Veltkamp, R. Tags: Angiography, Anticoagulants, Ischemic Stroke Brief Reports Source Type: research

Association between Fok1 and TaqI polymorphisms of vitamin D receptor gene with the severity of stenosis and calcification in carotid bulb in patients with ischemic stroke
CONCLUSIONS: There may be a biological association between the FokI VDR gene and carotid bulb calcification.PMID:35091316 | DOI:10.1016/j.jocn.2022.01.009
Source: Atherosclerosis - January 29, 2022 Category: Cardiology Authors: Farzaneh Foroughinia Najmeh Morovati Anahid Safari Mehdi Dianatpour Iman Jamhiri Seyed Taghi Heydari Sedighe Hooshmandi Afshin Borhani-Haghighi Source Type: research

Oral direct thrombin inhibitor as an alternative in the management of cerebral venous thrombosis: a series of 15 patients
ConclusionsWe report the largest series of cerebral vein thrombosis patients treated with dabigatran. Clinical outcome was excellent in most patients and not different from other studies. Dabigatran could possibly be considered an alternative to warfarin; nevertheless, further prospective assessment with randomized controlled studies is warranted.
Source: International Journal of Stroke - February 1, 2015 Category: Neurology Authors: Marcelo D. Mendonça, Raquel Barbosa, Vera Cruz‐e‐Silva, Sofia Calado, Miguel Viana‐Baptista Tags: Research Source Type: research

Intracerebral Hematoma Morphologic Appearance on Noncontrast Computed Tomography Predicts Significant Hematoma Expansion Clinical Sciences
Conclusions— Fluid levels, density heterogeneity, and margin irregularity on noncontrast CT are associated with hematoma expansion at 24 hours. These markers may assist in prediction of outcomes in scenarios where CT angiography is not readily available and may be of future help in refining the predictive value of the CT angiography spot sign.
Source: Stroke - October 26, 2015 Category: Neurology Authors: Blacquiere, D., Demchuk, A. M., Al-Hazzaa, M., Deshpande, A., Petrcich, W., Aviv, R. I., Rodriguez-Luna, D., Molina, C. A., Silva Blas, Y., Dzialowski, I., Czlonkowska, A., Boulanger, J.-M., Lum, C., Gubitz, G., Padma, V., Roy, J., Kase, C. S., Bhatia, R. Tags: Acute Cerebral Hemorrhage, Intracerebral Hemorrhage Clinical Sciences Source Type: research

IJERPH, Vol. 20, Pages 6145: Anticoagulant Treatment in Patients with AF and Very High Thromboembolic Risk in the Era before and after the Introduction of NOAC: Observation at a Polish Reference Centre
This study outlines reasons to initiate OAC treatment in very high-risk patients in clinical practice.
Source: International Journal of Environmental Research and Public Health - June 16, 2023 Category: Environmental Health Authors: Bernadetta Bielecka Iwona Gorczyca-G łowacka Agnieszka Ciba-Stemplewska Beata Wo żakowska-Kapłon Tags: Article Source Type: research

E-061 Moyamoya syndrome patients have low vitamin D
ConclusionOur data indicate a large proportion of moyamoya syndrome patients are deficient in vitamin D, which we hypothesize contributes to pathological severity. Future studies incorporating vitamin D supplementation may act as a novel intervention for this patient population that currently has few treatment options.Disclosures J. Fraser: None. L. Whitnel: None. J. Roberts: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Fraser, J., Whitnel, L., Roberts, J. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

Effect of Cystatin C Levels on Angiographic Atherosclerosis Progression and Events Among Postmenopausal Women With Angiographically Decompensated Coronary Artery Disease (from the Women’s Angiographic Vitamin and Estrogen WAVE Study)
End-stage renal disease and mild renal insufficiency are associated with increased cardiovascular risk. Cystatin C, a novel marker of kidney function, was found to be associated with a higher frequency of cardiovascular events and mortality independent of glomerular filtration rate. It remained uncertain, however, whether enhanced cardiovascular risk associated with cystatin C is due to accelerated progression of atherosclerosis or to plaque instability. The aim of this study was to examine the effects of baseline cystatin C on annual change in coronary artery narrowing and clinical events in 423 postmenopausal women with ...
Source: The American Journal of Cardiology - March 18, 2013 Category: Cardiology Authors: Dhavalkumar Patel, Soha Ahmad, Angela Silverman, Joseph Lindsay Tags: Coronary Artery Disease Source Type: research

Rationale and design of a randomized trial of apixaban vs warfarin to evaluate atherosclerotic calcification and vulnerable plaque progression
This study is a single‐center, prospective, randomized, open‐label study. From May 2014 to December 2015, 66 patients with nonvalvular AF who experienced VKA therapy were enrolled. Patients were randomized into either warfarin or apixaban cohorts and followed for 52 weeks. The primary objective is to compare the rate of change in coronary artery calcification (CAC) from baseline to follow‐up in apixaban vs warfarin cohorts. The key secondary objective is to compare the rate of incident plaques and quantitative changes in plaque types between patients randomized to either warfarin or apixaban cohorts using serial coro...
Source: Clinical Cardiology - July 1, 2017 Category: Cardiology Authors: Kazuhiro Osawa, Rine Nakanishi, Theingi Tiffany Win, Dong Li, Sina Rahmani, Negin Nezarat, Nasim Sheidaee, Matthew J. Budoff Tags: TRIAL DESIGNS Source Type: research

Bacteria and your broken heart
In your screening for heart disease, I bet your doctor will never think to check your gut. And that may well be where your heart problems start. Let me explain… Your gut plays a critical role in your overall health. It’s a major part of your body’s ecosystem. It’s home to trillions of bacteria, viruses and fungi. They make up your “microbiome.” Doctors are beginning to pay attention when it comes to these bacteria. But they’re still missing the big picture. This microcosm affects just about every organ and body system. Some of these gut bugs cause disease and infection. Others boost your immune system. Stil...
Source: Al Sears, MD Natural Remedies - October 19, 2017 Category: Complementary Medicine Authors: Cathy Card Tags: Heart Health Source Type: news

Low vitamin D levels affect left ventricular wall thickness in severe aortic stenosis
Conclusion Among patients with severe degenerative aortic stenosis, vitamin D deficiency is common. We found a significant association between left ventricular wall thickness and vitamin D levels, suggesting a potential role of this hormone in modulating hypertrophic remodelling in these patients. However, future larger studies are certainly needed to confirm our findings and to define their prognostic implications.
Source: Journal of Cardiovascular Medicine - October 6, 2020 Category: Cardiology Tags: Research articles: Valvular heart disease Source Type: research

Cardiovascular injuries during COVID-19 infection: A PROCESS-compliant case series from the Eastern Morocco
CONCLUSION: Cardiovascular involvement during COVID-19 should not be neglected and are associated with severe outcomes.PMID:33898022 | PMC:PMC8053362 | DOI:10.1016/j.amsu.2021.102309
Source: Annals of Medicine - April 26, 2021 Category: Internal Medicine Authors: Abdelilah El Rhalete Inas Rhazi Amine Bensaid Ikram Zaid Houssam Bkiyer Nabila Ismaili Nouha Elouafi Brahim Housni Source Type: research

Warfarin Treatment Is Associated to Increased Internal Carotid Artery Calcification
Conclusions: Long-lasting warfarin anticoagulation associated with increased calcification of carotid atherosclerotic plaques, particularly in locations known to be the predilection sites of stroke-causing plaques. The clinical significance of this novel finding warrants further investigations.
Source: Frontiers in Neurology - July 12, 2021 Category: Neurology Source Type: research

Intra-plaque calcium and its relation with the progression of carotid atheromatous disease
CONCLUSIONS: These results suggest that a higher content of Ca confers greater stability against the progression of carotid AD and, eventually, its ability to generate symptomatology.PMID:35583455 | DOI:10.23736/S0392-9590.22.04872-6
Source: International Angiology - May 18, 2022 Category: Cardiology Authors: Manuel Miralles Manel Arr ébola Aida Lago Sara Brugger Ra úl Lara Pilar Medina Albert Clar á Emma Plana Source Type: research