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Specialty: Neurology
Education: Study
Management: Hospitals

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Total 785 results found since Jan 2013.

24-hour on-duty shifts during the training of neurology residents in Spain: changes in the last decade
DISCUSSION: Residents' guidance during the 24-hour neurology on-duty shifts follows the path set by the training program and the national commission. However, there are still some differences that go beyond purely healthcare aspects. The future national program could establish new guidelines that help us achieve less heterogeneity, in order to offer the same training in the assessment of acute neurological patients.PMID:36285447 | DOI:10.33588/rn.7509.2022096
Source: Revista de Neurologia - October 26, 2022 Category: Neurology Authors: A Lambea-Gil H Tejada-Meza D M Cerd án-Santacruz Source Type: research

The mucormycosis and Stroke: the learning curve during the second COVID-19 pandemic
Background The Angio-invasive Rhino-orbito-cerebral mucormycosis (ROCM) producing strokes is a less explored entity. Our hospital, a stroke-ready one, had an opportunity to manage mucormycosis when it was identified as the nodal center for mucormycosis management. We are sharing our experiences and mistakes in managing the cerebrovascular manifestations of ROCM.Methods We conducted a prospective observational study during the second wave of the COVID-19 pandemic from 1st May 2021 to 30th September 2021, where consecutive patients aged more than 18 years with microbiologically confirmed cases of ROCM were included.
Source: Journal of Stroke and Cerebrovascular Diseases - October 12, 2022 Category: Neurology Authors: Dileep Ramachandran, Aravind R, Praveen Panicker, Jayaprabha S, MC Sathyabhama, Abhilash Nair, Raj S. Chandran, Simon George, Chintha S, Thomas Iype Source Type: research

Elevated Serum Ninjurin-1 Is Associated with a High Risk of Large Artery Atherosclerotic Acute Ischemic Stroke
AbstractNinjurin-1 is a novel adhesion molecule which is involved in many inflammatory diseases. Functional blockage of Ninjurin-1 has exerted an atheroprotective effect. The aim of the study is to explore the association between serum Ninjurin-1 and the risk of large artery atherosclerotic acute ischemic stroke. From August 2020 through December 2021, patients with large artery atherosclerotic acute ischemic stroke (LAA-AIS) admitted to the First Hospital Affiliated to Soochow University, and age- and sex-matched controls free of ischemic stroke were recruited. Serum Ninj1 was measured with an enzyme-linked immunosorbent ...
Source: Translational Stroke Research - October 7, 2022 Category: Neurology Source Type: research

ELECTRA-STROKE: Electroencephalography controlled triage in the ambulance for acute ischemic stroke —Study protocol for a diagnostic trial
DiscussionIf EEG can be used to identify LVO-a stroke patients with sufficiently high diagnostic accuracy, it may enable direct routing of these patients to an EVT-capable center, thereby reducing time-to-treatment and improving patient outcomes.Clinical trial registrationClinicalTrials.gov, identifier: NCT03699397.
Source: Frontiers in Neurology - October 3, 2022 Category: Neurology Source Type: research

Late-onset Fabry disease due to a new (p.Pro380Leu) pathogenic variant of GLA Gene
AbstractFabry disease is a rare X-linked lysosomal storage disorder due to pathogenic variants of the galactosidase alpha (GLA) gene, leading to a deficiency of alpha-galactosidase A. The inadequate enzymatic activity leads to progressive glycosphingolipids accumulation within tissues and subsequent multi-systemic dysfunction, with predominant involvement of heart, kidney, and nervous system. Two subtypes are recognized: the classic type and the late-onset type. We here describe the clinical characteristics of a patient with late-onset Fabry disease carrying a not previously identified GLA gene variant. This 50-year-old ma...
Source: Metabolic Brain Disease - September 30, 2022 Category: Neurology Source Type: research

Risk of readmission and mortality in patients with ischaemic stroke
Morton et al. conducted a 1-year follow-up study to evaluate the risk of readmission to hospital and all-cause mortality in patients with ischaemic stroke (IS) [1]. The cumulative incidence of all-cause readmission was 56.1%, and the adjusted hazard ratios (HRs) (95% confidence intervals [CI]) of patients with diabetes for all-cause, cardiovascular, and IS readmission were 1.13 (1.09 –1.17), 1.14 (1.07–1.21), and 1.17 (1.06–1.29). One-year mortality also increased significantly in patients with diabetes, and IS readmission and mortality were higher in women than those in men.
Source: Journal of the Neurological Sciences - September 30, 2022 Category: Neurology Authors: Tomoyuiki Kawada Source Type: research

Assessment of rehabilitation following intracerebral hemorrhage in China: findings from the Chinese stroke center alliance
This study showed that the rate of rehabilitation assessment was 74.2%, which is low. Rehabilitation assessment was associated with longer hospital stays and lower mortality. Therefore, patients with acute cerebral haemorrhage should undergo comprehensive and professional rehabilitation assessment.PMID:36126147 | DOI:10.1080/01616412.2022.2123174
Source: Neurological Research - September 20, 2022 Category: Neurology Authors: Jin-Ju Sun Yong-Mei Deng Dan-Dan Wang Hong-Qiu Gu Qi Zhou Yong-Jun Wang Zi-Xiao Li Xing-Quan Zhao Source Type: research

Quantifying the amount of greater brain ischemia protection time with pre-hospital vs. in-hospital neuroprotective agent start
The objective of this study is to quantify the increase in brain-under-protection time that may be achieved with pre-hospital compared with the post-arrival start of neuroprotective therapy among patients undergoing endovascular thrombectomy. In order to do this, a comparative analysis was performed of two randomized trials of neuroprotective agents: (1) pre-hospital strategy: Field administration of stroke therapy-magnesium (FAST–MAG) Trial; (2) in-hospital strategy: Efficacy and safety of nerinetide for the treatment of acute ischemic stroke (ESCAPE-NA1) Trial. In the FAST-MAG trial, among 1,041 acute ischemic stroke p...
Source: Frontiers in Neurology - September 13, 2022 Category: Neurology Source Type: research

Study Protocol: IMPETUS: Implementing a uniform stroke care pathway in medical colleges of India: IMPETUS Stroke
We present here a protocol to investigate the feasibility and fidelity of implementing a uniform stroke care pathway in medical colleges of India. Methods and Analysis: This is a multicentric, prospective, multiphase, mixed-method, quasi-experimental implementation study intended to examine the changes in a select set of stroke care-related indicators over time within the sites exposed to the same implementation strategy. We shall conduct process evaluation of the implementation process as well as evaluate the effect of the implementation strategy using the interrupted time series design. During implementation phase, educa...
Source: Annals of Indian Academy of Neurology - September 9, 2022 Category: Neurology Authors: Rohit Bhatia Partha Haldar Inder Puri MV Padma Srivastava Sanjeev Bhoi Menka Jha Anupam Dey Suprava Naik Satyabrata Guru Mamta Bhushan Singh VY Vishnu Roopa Rajan Anu Gupta Deepti Vibha Awadh Kishore Pandit Ayush Agarwal Manish Salunkhe Gunjan Singh Deeps Source Type: research