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Effect of COVID-19 pandemic on stroke admissions and quality of stroke interventional treatment in Masovian Voivodeship
CONCLUSIONS AND CLINICAL IMPLICATIONS: COVID-19's emergence was correlated with a significant reduction in admissions to stroke departments, particularly for TIAs, and a prolonged delay in reperfusion stroke treatment, especially in the drip-and-ship paradigm. An educational campaign to raise public awareness of TIA and/or stroke symptoms and immediate reorganisation of stroke care during the COVID-19 era are necessary.PMID:33783813 | DOI:10.5603/PJNNS.a2021.0025
Source: Neurologia i Neurochirurgia Polska - March 30, 2021 Category: Neurology Authors: Aleksander D ębiec Marta Bilik Piotr Piasecki Adam St ępień Jacek Staszewski Source Type: research

Risk Factors, and Clinical and Etiological Characteristics of Ischemic Strokes in COVID-19-Infected Patients: A Systematic Review of Literature
Conclusions: Ischemic strokes in COVID-19-infected patients were clinically severe, affecting younger patients mainly with Cry and cardioembolic etiologies. Further multicenter prospective registries are needed to better describe the causal association and the effect of COVID-19 infection on stroke.Cerebrovasc Dis
Source: Cerebrovascular Diseases - March 26, 2021 Category: Neurology Source Type: research

Higher Mortality of Ischaemic Stroke Patients Hospitalized with COVID-19 Compared to Historical Controls
Conclusions: Ischaemic stroke patients with COVID-19 had significantly higher 60-day all-cause mortality compared to propensity score-matched historical controls (ischaemic stroke patients without COVID-19).Cerebrovasc Dis
Source: Cerebrovascular Diseases - March 26, 2021 Category: Neurology Source Type: research

Stroke Care during the COVID-19 Pandemic: International Expert Panel Review
This study, prepared by a large international panel of stroke experts, assesses the rapidly growing research and personal experience with COVID-19 stroke and offers recommendations for stroke management in this challenging new setting: modifications needed for prehospital emergency rescue and hyperacute care; inpatient intensive or stroke units; posthospitalization rehabilitation; follow-up including at-risk family and community; and multispecialty departmental developments in the allied professions.Summary: The severe acute respiratory syndrome coronavirus 2 uses spike proteins binding to tissue angiotensin-converting enz...
Source: Cerebrovascular Diseases - March 23, 2021 Category: Neurology Source Type: research

Clinical and Radiological Characteristics of Acute Cerebrovascular Diseases Among Egyptian Patients With COVID-19 in Upper Egypt
Conclusion: Acute CVD among patients with COVID-19 was common in our study. LVO was the commonest. Hypertension, IHD, and anemia are the most common risk factors and could contribute to the worsening of clinical presentation. Comorbidities were common among patients with CVD, although a large number had elevated liver enzymes and creatinine that were partially due to COVID-19 infection itself. The current results begin to characterize the spectrum of CVD associated with COVID-19 in patients in Upper Egypt.Registration ID: The ID number of this study is IRB no: 17300470.
Source: Frontiers in Neurology - March 22, 2021 Category: Neurology Source Type: research

Acute Stroke Care during the COVID-19 Pandemic: Reduction in the Number of Admissions of Elderly Patients and Increase in Prehospital Delays
Conclusion: We observed a reduction in the number of acute strokes and TIAs admitted during the COVID-19 period. This drop affected especially elderly patients, and despite a delay in their arrival to the emergency department, the proportion of patients treated with recanalization therapies was preserved.Cerebrovasc Dis
Source: Cerebrovascular Diseases - March 17, 2021 Category: Neurology Source Type: research

Risk of Hemorrhagic Stroke in Patients With Coronavirus Disease 2019 —Reply
In Reply We thank Dr Silverman and colleagues for their interest in our study and providing us the opportunity to expand on our results. Among the 1916 patients who visited the emergency department or were hospitalized with coronavirus disease 2019 (COVID-19) in our study, 8 patients (0.4% [95% CI, 0.2%-0.8%]) had hemorrhagic stroke, including 7 with intracerebral hemorrhage and 1 with subarachnoid hemorrhage. Among these 8 patients, 4 strokes were attributed to anticoagulant use.
Source: JAMA Neurology - March 8, 2021 Category: Neurology Source Type: research

Stroke management during the coronavirus disease 2019 (COVID-19) pandemic: experience from three regions of the north east of Italy (Veneto, Friuli-Venezia-Giulia, Trentino-Alto-Adige)
ConclusionsOur study confirmed a decrease in admission rate of stroke patients in a large area of northern Italy during the lockdown period, especially during the first dramatic phase. Overall, there was no decrease in thrombolysis rate, confirming an effect of emergency care system for stroke patients. Instead, the significant decrease in thrombectomy rate during lockdown addresses some considerations of local and regional stroke networks during COVID-19 pandemic evolution.
Source: Neurological Sciences - March 4, 2021 Category: Neurology Source Type: research

Characteristics and outcomes of 100 consecutive patients with acute stroke and COVID-19
The coronavirus disease 2019 (COVID-19) pandemic started as a respiratory illness. Now, there are increasing reports of its hypercoagulable and thrombotic complications [1] leading to stroke [2,3]. Initial studies suggested strokes to be a feature of severe and late COVID-19 [2,4]; usually occurring in the second week of illness after the onset of typical respiratory symptoms [4]. Recent studies identified these even in mild to moderate infection [5,6]. A recent meta-analysis also noted that 24.5% of patients with stroke symptoms did not experience any of the other typical COVID- 19 symptoms [6].
Source: Journal of the Neurological Sciences - February 16, 2021 Category: Neurology Authors: Rajesh Benny, Rakeshsingh K. Singh, Anil Venkitachalam, Rakesh Shyam Lalla, Rahul A. Pandit, Keyur C. Panchal, Vibhor Pardasani, Gunjan Chanchalani, Mheboob Basle, Vyankatesh Bolegave, Hunnur Manoj, Ashutosh N. Shetty, Amit M. Shah, Pawan Pai, Nilesh M. B Source Type: research

Clinical features of neurological patients with coronavirus 2019: an observational study of one centre.
CONCLUSIONS: We studied a select group of patients (elderly, with comorbidities, and moderate or severe COVID-19 course). Pre-existing neurological disorders were additionally associated with a poorer prognosis and a high fatality rate (30%). Dementia and CNS vascular disorder were the most frequent pre-existing neurological conditions. The neurological symptoms of COVID-19 were various. We observed impaired consciousness, dizziness, headache, nausea, myalgia, psychomotor agitation and slowness, delirium, and psychoses. Further analysis is needed to elucidate the incidence of COVID-19 neurological complications. PMID:...
Source: Neurologia i Neurochirurgia Polska - February 2, 2021 Category: Neurology Authors: Zielińska-Turek J, Jasińska A, Kołakowska J, Szadurska J, Kosior DA, Dorobek M Tags: Neurol Neurochir Pol Source Type: research

COVID-19 Pathophysiology Predicts That Ischemic Stroke Occurrence Is an Expectation, Not an Exception —A Systematic Review
This study provides a comprehensive review of the pathobiology of COVID-19 and ischemic stroke. It also affirms that the immunological contribution to the pathophysiology of COVID-19 is predictive of the neurological sequelae particularly ischemic stroke, which makes it the expectation rather than the exception. This work is of fundamental significance to the neurorehabilitation community given the increasing number of COVID-related ischemic strokes, the current limited knowledge regarding the risk of reinfection, and recent reports of a PCNS. It further highlights the need for global collaboration and research into new pa...
Source: Frontiers in Neurology - January 28, 2021 Category: Neurology Source Type: research

Care Process of Recanalization Therapy for Acute Stroke during the COVID-19 Outbreak in South Korea.
CONCLUSIONS: These findings suggest that a prehospital delay occurred during the COVID-19 outbreak, and that patients with acute stroke might have been reluctant to visit and stay in hospitals. Our findings indicate that attention should be paid to prehospital care and the behavior of patients with acute stroke during the COVID-19 outbreak. PMID: 33480200 [PubMed]
Source: Journal of Clinical Neurology - January 24, 2021 Category: Neurology Tags: J Clin Neurol Source Type: research

Neurological symptoms, manifestations, and complications associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease 19 (COVID-19)
AbstractSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus, is responsible for the outbreak of coronavirus disease 19 (COVID-19) and was first identified in Wuhan, China in December 2019. It is evident that the COVID-19 pandemic has become a challenging world issue. Although most COVID-19 patients primarily develop respiratory symptoms, an increasing number of neurological symptoms and manifestations associated with COVID-19 have been observed. In this narrative review, we elaborate on proposed neurotropic mechanisms and various neurological symptoms, manifestations, and complications of COVI...
Source: Journal of Neurology - January 23, 2021 Category: Neurology Source Type: research

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