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Total 26 results found since Jan 2013.

The Potential of Stem Cell Therapy to Repair White Matter Injury in Preterm Infants: Lessons Learned From Experimental Models
Diffuse white matter injury (dWMI) is a major cause of morbidity in the extremely preterm born infant leading to life-long neurological impairments, including deficits in cognitive, motor, sensory, psychological and behavioral functioning. At present, no treatment options are clinically available to combat dWMI and therefore exploring novel strategies is urgently needed. In recent years, the pathophysiology underlying dWMI has slowly started to be unraveled, pointing towards the disturbed maturation of oligodendrocytes (OLs) as a key mechanism. Immature OL precursor cells in the developing brain are believed to be highly s...
Source: Frontiers in Physiology - May 8, 2019 Category: Physiology Source Type: research

Sex Difference of Radiation Response in Occupational and Accidental Exposure
Conclusion and Outlook This review summarizes the data from major human studies on the health risks of radiation exposure and shows that sex can potentially influence the prolonged response to radiation exposure (Figure 1 and Tables 1, 2). These data suggest that long-term radiosensitivity in females is higher than that in males who receive a comparable dose of radiation. Our analysis of the literature agrees with the conclusions of the recent report on the Biological effects of ionizing radiation (BEIR VII) published in 2006 by the National Academy of Sciences (NAS), United States (National Research Council, 2006). The B...
Source: Frontiers in Genetics - May 2, 2019 Category: Genetics & Stem Cells Source Type: research

Influence of Combined Transcranial Direct Current Stimulation and Motor Training on Corticospinal Excitability in Children With Unilateral Cerebral Palsy
Conclusion This proof-of-principle study evaluated the influence of cathodal contralesional tDCS on corticospinal excitability in pediatric participants with UCP. A hypothesized decrease in contralesional excitability was noted in participants in the Active+CIMT group, however, the efficacy of tDCS to modulate corticospinal excitability was not statistically different than the Sham+CIMT group. A more detailed understanding of how tDCS impacts M1 neurophysiology will be essential to inform future clinical trials on the optimal dosing parameters, based on individual brain circuitry, to explore the potential functional benef...
Source: Frontiers in Human Neuroscience - April 23, 2019 Category: Neuroscience Source Type: research

A case report on middle cerebral artery aneurysm treated by rapid ventricular pacing: A CARE compliant case report
Rationale: Cerebral aneurysm is a common cause of intracranial hemorrhage, stroke, and death. It is treated with vascular surgeries, such as coil embolism and artery clipping. However, surgery itself is a risk factor that may cause rupture of aneurysm, and leads to irreversible brain damage, and even death. Rapid ventricular pacing (RVP) is a procedure that temporarily lowers blood pressure by increasing heart rate and reducing ventricular filling time. RVP has been widely used to reduce blood vessel tension in many cardiovascular surgeries. Patient concerns: A 46-year-old man came to our hospital with intermittent ri...
Source: Medicine - November 1, 2018 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

4 Key Insights When Raising Money for Your Medtech Startup: Interview with Bruce Shook, CEO of Intact Vascular
Welcome to the Medsider interview series, a regular feature at MassDevice. All interviews are conducted by Scott Nelson, Founder of Medsider and Group Director for WCG. We hope you enjoy them! Bruce Shook joined Intact Vascular in 2014 as President and CEO. A highly-experienced, medical device executive with more than 30 years of industry experience, Bruce was previously Co-founder, Director, President, and CEO of Neuronetics, which is a privately held medical device company that markets a non-invasive brain stimulation technology for the treatment of depression. Previously, Shook was Co-founder, Director, President, an...
Source: Mass Device - February 27, 2017 Category: Medical Equipment Authors: Danielle Kirsh Tags: Blog medsider Source Type: news

Design Your Healthy and Happy Life With 3 Quick Makeovers: Small Steps Equal a Big Impact
Design your healthy and happy life with these super quick makeover tips that will have you wanting more. A healthy and happy life is about living blissfully, with passion and purpose, not just about the absence of disease. The great news is that we can design our own healthy lifestyle plan just like interior designers create beautiful spaces; we can design it no matter where we are in your own health journey; dealing with an illness, or recovering from an injury. What's even better news is that we don't need to do a complete overhaul. Who doesn't love a quick makeover? Sometimes, all it takes is new throw pillows or a bold...
Source: Healthy Living - The Huffington Post - September 29, 2015 Category: Consumer Health News Source Type: news

The Most Beautiful Dance I Ever Enjoyed With My Husband
This past weekend my husband, Dan danced at our friend's daughter's wedding. Well, if you consider swaying from side to side dancing, then it qualifies. While it may not seem so remarkable, the fact that Dan wiggled on a dance floor is amazing and wonderful! It was just five years ago that his life took a cruel turn and he suffered a devastating stroke. He couldn't walk, talk or eat. He had a feeding tube in his stomach, and we were told he was "gravely" ill. The stroke had affected his brain stem where bodily functions were regulated, paralyzed the optic nerve and traveled beyond. He received tPA -- tissue plasminogen ac...
Source: Healthy Living - The Huffington Post - September 15, 2015 Category: Consumer Health News Source Type: news

Strategy Training Shows Promise for Addressing Disability in the First 6 Months After Stroke
Conclusions. Strategy training shows promise for addressing disability in the first 6 months after stroke. Lessons from this pilot study may inform future clinical trials.
Source: Neurorehabilitation and Neural Repair - July 21, 2015 Category: Neurology Authors: Skidmore, E. R., Dawson, D. R., Butters, M. A., Grattan, E. S., Juengst, S. B., Whyte, E. M., Begley, A., Holm, M. B., Becker, J. T. Tags: Clinical Research Articles Source Type: research

Meet the Chinese Lumberjack Who Slept With an Alien
"If you can't find me," Meng Zhaoguo said over a cell phone whose signal faded from its isolation, "Just head to the last house on the logging commune lane. Or ask anyone who's around." Everyone knows the first Chinese person to allegedly be abducted by aliens. With its surging economy, China is summiting once-unseen heights in world rankings: millions of English speakers, almost the most millionaires and actually the least frugal tourists. Yet despite being slightly larger in area than the United States with four times as many people, China trails far behind when it comes to visitors from outer space. To date, only one C...
Source: Science - The Huffington Post - April 7, 2015 Category: Science Source Type: news

Practical experience with the TAG and conformable TAG devices: lessons learned in about 100 cases.
Conclusion: This single-center study demonstrates acceptable rates for operative mortality and major adverse events after endovascular repair of various thoracic aortic pathologies with both generations of Gore TAG device. However, a better knowledge in long-term results is necessary to define target populations. PMID: 24002390 [PubMed - in process]
Source: The Journal of Cardiovascular Surgery - September 6, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Georg Y, Schwein A, Lejay A, Tartaglia E, Girsowicz E, Kretz JG, Thaveau F, Chakfe N Tags: J Cardiovasc Surg (Torino) Source Type: research

Joe Farman obituary
Scientist whose discovery of the depletion of the ozone layer sparked global action to phase out dangerous chemicalsJoe Farman, who has died aged 82, was the leader of a small group of scientists who made one of the most important discoveries in recent history. In 1985, they published a landmark paper on the ozone layer, the protective skin that filters the sun's ultraviolet rays and without which the rays can cause cancers and eye damage. Their research showed that the ozone layer was being rapidly depleted over the Antarctic.Just two years later, world governments signed the Montreal protocol, a treaty phasing out the us...
Source: Guardian Unlimited Science - May 16, 2013 Category: Science Authors: Fiona Harvey Tags: Obituaries Ozone layer guardian.co.uk Physics Environment Science Source Type: news