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Iron Metabolism and Brain Development in Premature Infants
Yafeng Wang1,2,3, Yanan Wu2, Tao Li1,2,3, Xiaoyang Wang2,4 and Changlian Zhu2,3* 1Department of Neonatology (NICU), Children’s Hospital Affiliated Zhengzhou University, Zhengzhou, China 2Henan Key Laboratory of Child Brain Injury, Institute of Neuroscience and Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China 3Department of Clinical Neuroscience, Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden 4Department of Physiology, Sahlgrenska Academy, Institute of Neuroscience and Physiology, University of Got...
Source: Frontiers in Physiology - April 24, 2019 Category: Physiology Source Type: research

What to Know About High Triglycerides
Discussions about heart health often center around blood pressure and cholesterol, with factors like poor sleep, smoking, family history of heart disease, and chronic stress thrown in. However, there’s one variable that doesn’t get covered as often, even though it can be an important indicator of cardiovascular risk: triglycerides. “We don’t really talk about triglycerides very much, especially compared to cholesterol, but they’re actually an essential part of understanding heart health,” says Dr. Adriana Quinones-Camacho, a cardiologist at NYU Langone Health in New York. “For some...
Source: TIME: Health - May 23, 2023 Category: Consumer Health News Authors: Elizabeth Millard Tags: Uncategorized healthscienceclimate heart health Source Type: news

Spinal cord infarction in diabetic pregnancy: A case report
Abstract Spinal cord infarction (SCI) is uncommon as compared to cerebral stroke. Moreover, SCI during pregnancy is rare. Here, we report a case of SCI in diabetic pregnancy, properly diagnosed, promptly treated, and a good prognosis achieved. A 38‐year‐old, pregnant woman, para 1, with type 1 diabetes mellitus on insulin since 14 years of age, was admitted to our hospital for paresthesia and numbness in the lower left side of the body, with movement disturbances. On the basis of the temporal profile of the onset and the multiple resonance imaging scans, SCI was diagnosed. Steroid pulse therapy and low‐dose aspirin a...
Source: Journal of Obstetrics and Gynaecology Research - July 15, 2013 Category: OBGYN Authors: Takeru Sugihara, Koichiro Kido, Yukifumi Sasamori, Masahiro Shiba, Takuya Ayabe Tags: Case Report Source Type: research

Empty Handoff
A 29-year-old man with brittle diabetes (ie, frequent, severe changes in blood glucose levels) was admitted to surgery for incision and drainage of a leg infection. The patient had a history of chronic renal failure, hypertension, and stroke after a hypoglycemic event. While on the hospital floor before surgery, the patient's blood glucose level fell precipitously after he received insulin, and he required glucose several times. Because of the workload, the nurse did not accompany the patient to the OR but instead informed the transportation assistant about the patient's extreme sensitivity to insulin and asked that the i...
Source: AORN Journal - February 28, 2014 Category: Nursing Tags: Perioperative Grand Rounds Source Type: research

More than a stretch: Yoga’s benefits may extend to the heart
As a long-time yoga enthusiast, I’m always happy to hear about benefits newly attributed to this ancient practice. Doing yoga for a few hours each week helps me feel calmer and more balanced, both physically and mentally. Now, new research suggests that my habit also may be helping my heart. A recent review of yoga and cardiovascular disease published in the European Journal of Preventive Cardiology indicates that yoga may help lower heart disease risk as much as conventional exercise, such as brisk walking. As I write in the April issue of the Harvard Heart Letter, the studies in the review looked at different types...
Source: New Harvard Health Information - April 15, 2015 Category: Consumer Health News Authors: Julie Corliss Tags: Complementary and alternative medicine Heart Health alternative therapy cardiovascular disease exercise yoga Source Type: news

Cardiovascular safety of albiglutide in the Harmony programme: a meta-analysis
Publication date: Available online 11 August 2015 Source:The Lancet Diabetes & Endocrinology Author(s): Miles Fisher, Mark C Petrie, Philip D Ambery, Jill Donaldson, John J V McMurray, June Ye Background Albiglutide is a glucagon-like peptide-1 receptor agonist, a new class of drugs used to treat type 2 diabetes. We did a prospective meta-analysis of the cardiovascular safety of albiglutide as stipulated by the US Food and Drug Administration recommendations for the assessment of new treatments for diabetes. Methods We did a meta-analysis of eight phase 3 trials and one phase 2b trial in which patients wer...
Source: The Lancet Diabetes and Endocrinology - August 12, 2015 Category: Endocrinology Source Type: research

Influence of glycaemic control on the outcomes of patients treated by intravenous thrombolysis for cerebral ischaemia
Abstract Whether the glycaemic control during the first hours of cerebral ischaemia treated by thrombolysis influences outcomes remains unsettled. We aimed at evaluating the quality of the glycaemic control and whether patients with well-controlled glycaemia after thrombolysis for acute cerebral ischaemia have better outcomes. We retrospectively analysed data prospectively collected in consecutive stroke patients who received i.v. thrombolysis at the Lille University Hospital. Patients with glycaemia >1.6 g/l (8.9 mmol/l) at any point during the first 48 h received insulin. We used 2 definitions of well cont...
Source: Journal of Neurology - August 14, 2015 Category: Neurology Source Type: research

The type of fat you eat matters!
By: JoAnn E. Manson, MD, DrPH, and Shari S. Bassuk, ScD Contributing Editors, Brigham and Women’s Hospital, Harvard Medical School If you saw last month’s news headlines declaring that saturated fat is no longer deemed harmful to your heart, you may be (understandably!) confused. After all, for years, clinicians and scientists have recommended reducing saturated fat for heart health. Is it time to rethink this advice? Hardly. Here’s the deal. The research that sparked the recent news splash was an analysis by Canadian researchers of up to a dozen long-term observational studies of diet that included a total of 90,000...
Source: New Harvard Health Information - September 22, 2015 Category: Consumer Health News Authors: Contributing Editors Tags: Health Healthy Eating Fats saturated fats unsaturated fats Source Type: news

Safety and efficacy of glucose-insulin-potassium treatment in coronary artery bypass graft surgery and percutaneous coronary intervention
The purpose of this meta-analysis was to evaluate protective effects of glucose–insulin–potassium (GIK) on outcomes after coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI). We systematically searched Medline/Pubmed, Elsevier, Embase, Web of Knowledge and Google Scholar. A total of 1206 studies were retrieved during the extensive literature search of all major databases; however, 38 trials reporting the end-point of interest were selected. We performed a pooled analysis of outcomes following PCI: incidence of cardiac arrest [odds ratio (OR) of 0.91; 95% confidence interval (CI): ...
Source: Interactive CardioVascular and Thoracic Surgery - October 19, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Ali-Hassan-Sayegh, S., Mirhosseini, S. J., Zeriouh, M., Dehghan, A. M., Shahidzadeh, A., Karimi-Bondarabadi, A. A., Sabashnikov, A., Popov, A.-F. Tags: Congestive Heart Failure Adult Cardiac Source Type: research

How Alcohol Use Affects Health
You may have heard of Dry January, a campaign run in the U.K. by Alcohol Concern. To promote alcohol awareness, it involves (as you’ve likely gathered) completely abstaining from alcohol for the month of January. It’s a valuable campaign with noble intentions, but a minority of participants may unfortunately miss the wider point. A month of strict abstinence does lead some to drink more than they should come February 1. Remaining alcohol free for a month is an achievement which deserves to be rewarded, but compensatory drinking is not what Dry January is trying to advocate. A healthy attitude towards consumption (not ...
Source: Psych Central - February 13, 2016 Category: Psychiatry Authors: Dr. Wayne Osborne Tags: Addictions Alcoholism General Healthy Living Substance Abuse Abstinence Alcohol Abuse Alcoholic beverage Binge Drinking Drinking culture Liver disease Liver health Long-term effects of alcohol Moderation National Council on Alc Source Type: news

Id: 64: reversible blindness associated with diabetic ketoacidosis: a rare combination
Discussion Sudden painless vision loss has a wide differential diagnosis and it is usually caused by ischemia at retinal, ocular or cortical level. No history of methanol ingestion or trauma, normal fundoscopy, normal MRI and rapid return of vision after correction of diabetic ketoacidosis strongly suggests that blindness was related to acidosis. Alcoholic ketoacidosis has been reported to cause transient reversible blindness in other case reports and correction of acidosis lead to reversal of blindness. Other rare causes of reversible blindness include posterior reversible encephalopathy syndrome, brain tumors, anterior i...
Source: Journal of Investigative Medicine - March 21, 2016 Category: Research Authors: Asad, Z., Chaudhary, A., Awab, A. Tags: Pulmonary/Critical Care Source Type: research

Lasting Impact of an Ephemeral Organ: The Role of the Placenta in Fetal Programming
Recent advances in molecular and imaging technologies, “omics” fields, and data sciences are offering researchers an unprecedented look at the placenta, the master regulator of the fetal environment.© EPA/National Geographic Channel/Alamy Studies of infants conceived during the Dutch “Hunger Winter” provided some of the earliest clues that prenatal stress could affect health much later in life.© Nationaal Archief  © Evan Oto/Science Source In one study, the placental microbiome had a similar taxonomic profile as the oral microbiome, illustrated here by...
Source: EHP Research - July 1, 2016 Category: Environmental Health Authors: Web Admin Tags: Featured Focus News July 2016 Source Type: research

Outcomes for Patients With Diabetes After Continuous-Flow Left Ventricular Assist Device Implantation
Diabetes mellitus (DM) affects an estimated 366 million people worldwide, and confers a markedly increased risk of cardiovascular disease, including coronary artery disease (CAD), stroke, and HF.1 Diabetes is an independent mortality risk factor for HF patients at follow-up intervals of 1 –8 years.2–5 Decompensated HF is an insulin-resistant state, promoting hyperglycemia in patients with and without DM. Independently from DM status, blood glucose level at HF hospital admission is prognostic for 30-day mortality.
Source: Journal of Cardiac Failure - February 24, 2016 Category: Cardiology Authors: Amanda R. Vest, Stanley M. Mistak, Rory Hachamovitch, Maria M. Mountis, Nader Moazami, James B. Young Tags: Clinical Investigation Source Type: research

Declines In Dementia: Of Hearts And Minds
In this season when we are meant to be thankful, but when so many of us have had so many reasons to be otherwise, we have received a timely, welcome bit of universally good news. Rates of dementia in the United States appear to be declining. This news reaches us courtesy of a study published recently in JAMA Internal Medicine. The investigators used standard, validated measures of cognitive function and dementia in two groups of more than 10,000 people in the U.S. with an average age of roughly 75 in the year 2000, and again in 2012. The overall rate of dementia declined over that span from 11.6% to 8.8%. Taking ...
Source: Science - The Huffington Post - November 27, 2016 Category: Science Source Type: news

Does Diet Soda Cause Weight Gain?
This study shows quite nicely that non-caloric sweeteners can alter gut microbes in mice -- a change that has negative metabolic consequences -- and provides preliminary evidence that it can happen in humans too. Unexpected consequences To further appreciate how complicated our handling of diet soda can be, here's another little example: Our intestine (or bowel) is covered with cells that secrete hormones. These cells react to the presence and composition of food by secreting peptides such as glucagon-like peptide 1 (GLP-1), peptide YY (PYY) and cholecystokinin - these names are not important - that work on the brain, sig...
Source: Healthy Living - The Huffington Post - December 7, 2016 Category: Consumer Health News Source Type: news

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