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Drug: Tetracycline

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Total 6023 results found since Jan 2013.

Intracanal irrigants for pulpectomy in primary teeth: a systematic review and meta‐analysis
ConclusionsMore studies are required with adequate quality, as well as a full‐result report, including summary measurements of both response variables and effect size, to determine the most effective irrigant agents for use in pulpectomies.
Source: International Journal of Paediatric Dentistry - February 22, 2016 Category: Dentistry Authors: Amaury Pozos‐Guillen, Adrian Garcia‐Flores, Vicente Esparza‐Villalpando, Arturo Garrocho‐Rangel Tags: Review Source Type: research

Systemic and topical antibiotics for chronic rhinosinusitis.
CONCLUSIONS: We found very little evidence that systemic antibiotics are effective in patients with chronic rhinosinusitis. We did find moderate quality evidence of a modest improvement in disease-specific quality of life in adults with chronic rhinosinusitis without polyps receiving three months of a macrolide antibiotic. The size of improvement was moderate (0.5 points on a five-point scale) and only seen at the end of the three-month treatment; by three months later no difference was found.Despite a general understanding that antibiotics can be associated with adverse effects, including gastrointestinal disturbances, th...
Source: Cochrane Database of Systematic Reviews - April 25, 2016 Category: Journals (General) Authors: Head K, Chong LY, Piromchai P, Hopkins C, Philpott C, Schilder AG, Burton MJ Tags: Cochrane Database Syst Rev Source Type: research

Intracanal irrigants for pulpectomy in primary teeth: a systematic review and meta ‐analysis
ConclusionsMore studies are required with adequate quality, as well as a full‐result report, including summary measurements of both response variables and effect size, to determine the most effective irrigant agents for use in pulpectomies.
Source: International Journal of Paediatric Dentistry - February 21, 2016 Category: Dentistry Authors: Amaury Pozos ‐Guillen, Adrian Garcia‐Flores, Vicente Esparza‐Villalpando, Arturo Garrocho‐Rangel Tags: Review Source Type: research

Antibiotic prophylaxis for elective hysterectomy.
CONCLUSIONS: Antibiotic prophylaxis appears to be effective in preventing postoperative infection in women undergoing elective vaginal or abdominal hysterectomy, regardless of the dose regimen. However, evidence is insufficient to show whether use of prophylactic antibiotics influences rates of adverse effects. Similarly, evidence is insufficient to show which (if any) individual antibiotic, dose regimen, or route of administration is safest and most effective. The most recent studies included in this review were 14 years old at the time of our search. Thus findings from included studies may not reflect current practice in...
Source: Cochrane Database of Systematic Reviews - June 18, 2017 Category: General Medicine Authors: Ayeleke RO, Mourad S, Marjoribanks J, Calis KA, Jordan V Tags: Cochrane Database Syst Rev Source Type: research

Resistance of Staphylococcus aureus to antimicrobial agents in Ethiopia: a meta-analysis
ConclusionsS. aureus in Ethiopia has gotten notoriously resistant to almost to all of antimicrobial agents in use including, penicillin, cephalosporins, tetracyclines, chloramphenicol, methicillin, vancomycin and sulphonamides. The resistance level to vancomycin is bothersome and requires a due attention. Continued and multidimensional efforts of antimicrobial stewardship program promoting rational use of antibiotics, infection prevention and containment of AMR are urgently needed.
Source: Antimicrobial Resistance and Infection Control - August 23, 2017 Category: Infectious Diseases Source Type: research

Omadacycline: A New Tetracycline Antibiotic.
CONCLUSION: Omadacycline is an alternative treatment option for ABSSSI and CABP. PMID: 30917674 [PubMed - in process]
Source: The Annals of Pharmacotherapy - March 29, 2019 Category: Drugs & Pharmacology Authors: Dougherty JA, Sucher AJ, Chahine EB, Shihadeh KC Tags: Ann Pharmacother Source Type: research

Major Traditional Probiotics: Comparative Genomic Analyses and Roles in Gut Microbiome of Eight Cohorts
This study provides conceptual advances that lays the foundation for future applications in personalized probiotics, which must consider both the species/strain heterogeneity and individual heterogeneity. Author Contributions GH and GL designed the study. GL, BL, CY, YW, XB, WL, and FL performed the experiments and analyzed the data. GL wrote the manuscript. Funding This research was supported by the National Key R&D Program of China (Grant No. 2017YFD0400303). Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that cou...
Source: Frontiers in Microbiology - April 8, 2019 Category: Microbiology Source Type: research

Aedes –Chikungunya Virus Interaction: Key Role of Vector Midguts Microbiota and Its Saliva in the Host Infection
Conclusion and Perspectives Arbovirus infections, such as CHIKV, have been growing worldwide and are becoming a major public health problem, especially in immuno-compromised classes such as children and the elderly. CHIKV is dangerous since it can cause arthritis, fever and other impairments, making it necessary to seek new ways to counter the proliferation of this virus. Knowing the vector’s competence is fundamentally important, including an understanding of the vector virus interaction and the modulation of this interaction. Despite advances in the knowledge of mosquito competence in the transmission of CHIKV, l...
Source: Frontiers in Microbiology - April 8, 2019 Category: Microbiology Source Type: research

Identification of a nth-Like Gene Encoding an Endonuclease III in Campylobacter jejuni
In this study, a BER homolog encoded by cj0595c (named nth) in C. jejuni was analyzed for endonuclease III activity and for its role in maintaining genomic stability. It was found that inactivation of nth resulted in elevated frequencies of spontaneous fluoroquinolone-resistant (FQR) and oxidative stress resistant (OXR) mutants, compared with the wild-type strain in C. jejuni. Sequencing analysis of the FQR and OXR mutants revealed that the elevated mutation rates were associated with C → T or G → A transition in gyrA (FQR mutants) or perR (for OXR mutants). In an in vitro assay, a purified recombinant C. jej...
Source: Frontiers in Microbiology - April 9, 2019 Category: Microbiology Source Type: research

Microbiota of the Gut-Lymph Node Axis: Depletion of Mucosa-Associated Segmented Filamentous Bacteria and Enrichment of Methanobrevibacter by Colistin Sulfate and Linco-Spectin in Pigs
This study aimed to characterize shifts in microbial community structure across the intestinal mucosa-enteric lymph node axis in order to understand the effects of two commonly used antibiotics (Linco-Spectin and Colistin sulfate; oral application). We hypothesized that these antibiotics influence GI microbiota diversity and community structure and that, as a result, the ICLN-ileum axis is altered through permeability changes and changed translocation patterns. Medicated-feed antibiotics are still heavily used, not only in the E.U. but worldwide in case of infections. In addition to the taxonomic community profiling survey...
Source: Frontiers in Microbiology - April 10, 2019 Category: Microbiology Source Type: research

Validation of a 16th Century Traditional Chinese Medicine Use of Ginkgo biloba as a Topical Antimicrobial
This study aimed to examine the traditional use of Ginkgo seeds as topical treatment for skin disorders for potential antibacterial efficacy. This is the first study to test and compare the antibacterial activity of various Ginkgo seed extracts on skin pathogens. In this work, we confirmed the ethnomedicinal importance of seeds in the treatment of skin diseases. As reported in the Compendium of Materia Medica Ben Cao Gang Mu, only the seeds were used for medicinal uses, especially as a topical treatment for skin infections. Moreover, our study validates the antimicrobial activity of the seed (i.e., seed coats and immature...
Source: Frontiers in Microbiology - April 15, 2019 Category: Microbiology Source Type: research

Microbial Diversity and Antimicrobial Resistance Profile in Microbiota From Soils of Conventional and Organic Farming Systems
According to this study it may be outlined that soil microbiota is a stable component as it were detected similar composition of microorganisms in soil both in organic as well as in conventional farming systems with similar soil structure and pH. The different amount of phosphorus in soils had no influence on bacterial variety at a genera level although more investigations would be useful to investigate changes among separate species. During evolution microorganisms adapted to survive in ecosystems independently of certain changes and probably serve as a buffer for ecological niches. It is unclear, however, what level of i...
Source: Frontiers in Microbiology - April 25, 2019 Category: Microbiology Source Type: research

Head-to-head oral prophylactic antibiotic therapy for chronic obstructive pulmonary disease.
CONCLUSIONS: It is not clear from the evidence included in this review whether there is a difference in efficacy or safety between different classes or regimens of prophylactic antibiotic, given for 12 to 13 weeks to people with COPD. Whilst no head-to-head comparisons of antibiotic resistance were identified, concerns about this continue. The sample size in this review is small and both included studies are of short duration. Thus, there is considerable uncertainty in effects observed and the effects of different prophylactic antibiotics requires further research. PMID: 31125127 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - May 23, 2019 Category: General Medicine Authors: Threapleton CJ, Janjua S, Fortescue R, Baker EH Tags: Cochrane Database Syst Rev Source Type: research

Antibiotics for trachoma.
CONCLUSIONS: Antibiotic treatment may reduce the risk of active trachoma and ocular infection in people infected with C trachomatis, compared to no treatment/placebo, but the size of the treatment effect in individuals is uncertain. Mass antibiotic treatment with single dose oral azithromycin reduces the prevalence of active trachoma and ocular infection in communities. There is no strong evidence to support any variation in the recommended periodicity of annual mass treatment. There is evidence of an increased risk of antibiotic resistance at 12 months in communities treated with antibiotics. PMID: 31554017 [PubMed ...
Source: Cochrane Database of Systematic Reviews - September 25, 2019 Category: General Medicine Authors: Evans JR, Solomon AW, Kumar R, Perez Á, Singh BP, Srivastava RM, Harding-Esch E Tags: Cochrane Database Syst Rev Source Type: research

Prevalence of fluoroquinolone-resistant Salmonella serotypes in Iran: a meta-analysis.
Authors: Khademi F, Vaez H, Ghanbari F, Arzanlou M, Mohammadshahi J, Sahebkar A Abstract The present study was conducted to investigate the antimicrobial susceptibility profiles of Salmonella serotypes, especially fluoroquinolone-resistant strains, recovered from clinical samples in Iran. A full electronic search using related keywords was conducted in Persian and English languages in ISI Web of Knowledge, PubMed, Scopus, Google Scholar and the Scientific Information Database (SID) search engines to find papers published between 1983 and 1 July 2019. According to the inclusion and exclusion criteria, 46 eligible ar...
Source: Pathogens and Global Health - February 7, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research