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Specialty: Cardiology
Drug: Aspirin

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Total 932 results found since Jan 2013.

Aspirin plus clopidogrel versus aspirin Mono-Therapy for ischemic stroke.
Authors: Kumar A, Shariff M, Doshi R PMID: 31994939 [PubMed - as supplied by publisher]
Source: Scandinavian Cardiovascular Journal - January 30, 2020 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

A 28-year-old male with spontaneous coronary artery dissection complicated by apical thrombus and acute ischemic stroke: An interesting case
Radiol Case Rep. 2022 Nov 2;18(1):246-249. doi: 10.1016/j.radcr.2022.10.001. eCollection 2023 Jan.ABSTRACTSpontaneous coronary artery dissection is described as the intramural bleeding that separates the layers of an epicardial coronary artery wall, either with or without an intimal tear. Atherosclerosis, iatrogenic damage, or trauma are not linked to this syndrome. Here we present a 28-year-old male with 1 month history stroke but no any chronic disease as well family history of heart disease who presented with 2 days' duration of typical cardiac chest pain. Based on an emergency electrocardiogram that showed biphasic T-w...
Source: Atherosclerosis - November 10, 2022 Category: Cardiology Authors: Said Abdirahman Ahmed Mesut Karata ş L ütfi Öcal Mohamed Abdullahi Mohamud Ishak Ahmed Abdi Mohamed Omar Hassan Source Type: research

Searching for Atrial Fibrillation Poststroke: A White Paper of the AF-SCREEN International Collaboration.
H, Kirchhof P, Korompoki E, Krieger DW, Lip GYH, Løchen ML, Mairesse GH, Montaner J, Neubeck L, Ntaios G, Piccini JP, Potpara TS, Quinn TJ, Reiffel JA, Ribeiro ALP, Rienstra M, Rosenqvist M, Sakis T, Sinner MF, Svendsen JH, Van Gelder IC, Wachter R, Wijeratne T, Yan B Abstract Cardiac thromboembolism attributed to atrial fibrillation (AF) is responsible for up to one-third of ischemic strokes. Stroke may be the first manifestation of previously undetected AF. Given the efficacy of oral anticoagulants in preventing AF-related ischemic strokes, strategies of searching for AF after a stroke using ECG monitoring fol...
Source: Circulation - November 25, 2019 Category: Cardiology Authors: Schnabel RB, Haeusler KG, Healey JS, Freedman B, Boriani G, Brachmann J, Brandes A, Bustamante A, Casadei B, Crijns HJGM, Doehner W, Engström G, Fauchier L, Friberg L, Gladstone DJ, Glotzer TV, Goto S, Hankey GJ, Harbison JA, Hobbs FDR, Johnson LSB, Kame Tags: Circulation Source Type: research

Benefit of Anticoagulation Therapy in Hyperthyroidism‐Related Atrial Fibrillation
ConclusionsPatients with hyperthyroidism‐related AF are at high risk of stroke (3.9% per year). Warfarin confers stroke prevention in patients with CHA2DS2‐VASc ≥1 and non–self‐limiting AF. Overall stroke risk was lower in hyperthyroid non–self‐limiting AF patients compared with nonhyperthyroid counterparts.
Source: Clinical Cardiology - July 1, 2015 Category: Cardiology Authors: Pak‐Hei Chan, Jojo Hai, Chun‐Yip Yeung, Gregory Y.H. Lip, Karen Siu‐Ling Lam, Hung‐Fat Tse, Chung‐Wah Siu Tags: Clinical Investigations Source Type: research

Modification of Outcomes With Aspirin or Apixaban in Relation to CHADS2 and CHA2DS2-VASc Scores in Patients With Atrial Fibrillation: A Secondary Analysis of the AVERROES Study Original Articles
Conclusions— In an atrial fibrillation population, apixaban was superior to aspirin for stroke prevention, with similar rates of major bleeding, in the presence of one or more stroke risk factors, with consistency of the treatment effect by CHADS2/CHA2DS2-VASc scores.
Source: Circulation: Arrhythmia and Electrophysiology - February 19, 2013 Category: Cardiology Authors: Lip, G. Y. H., Connolly, S., Yusuf, S., Shestakovska, O., Flaker, G., Hart, R., Lanas, F., Xavier, D., Eikelboom, J., on behalf of the AVERROES Investigators Tags: Anticoagulants, Antiplatelets Original Articles Source Type: research

CYP2C19 Metabolizer Status and Clopidogrel Efficacy in the Secondary Prevention of Small Subcortical Strokes (SPS3) Study Genetics
Conclusions There were significant differences in recurrent stroke by CYP2C19 genotype-inferred metabolizer status in white subcortical stroke patients receiving dual antiplatelet therapy with aspirin and clopidogrel, consistent with cardiovascular studies on CYP2C19 and clopidogrel; however, the bleeding risk that led to early termination of the antiplatelet arm of the SPS3 trial does not appear to be explained by CYP2C19 genotype. This study was relatively underpowered; therefore, these findings should be interpreted with caution and warrant replication. Clinical Trial Registration URL: www.clinicaltrials.gov. Unique id...
Source: JAHA:Journal of the American Heart Association - May 27, 2015 Category: Cardiology Authors: McDonough, C. W., McClure, L. A., Mitchell, B. D., Gong, Y., Horenstein, R. B., Lewis, J. P., Field, T. S., Talbert, R. L., Benavente, O. R., Johnson, J. A., Shuldiner, A. R. Tags: Genetics Source Type: research

Intracranial atherosclerotic stenosis: risk factors, diagnosis, and treatment
Lancet Neurol. 2022 Feb 7:S1474-4422(21)00376-8. doi: 10.1016/S1474-4422(21)00376-8. Online ahead of print.ABSTRACTIntracranial atherosclerotic stenosis (ICAS) is one of the most frequent causes of stroke worldwide and confers one of the greatest risks of recurrent stroke compared with other causes of stroke. Asymptomatic ICAS is increasingly recognised as a risk factor for silent brain infarctions and dementia, magnifying the global burden of ICAS. Although ICAS is a lumen-based diagnosis, newer diagnostic imaging techniques, such as high-resolution MRI, might help to identify high-risk population subgroups to test interv...
Source: Atherosclerosis - February 10, 2022 Category: Cardiology Authors: Jose Gutierrez Tanya N Turan Brian L Hoh Marc I Chimowitz Source Type: research

Atrial Fibrillation Patients Categorized as “Not for Anticoagulation” According to the 2014 Canadian Cardiovascular Society Algorithm Are Not “Low Risk”
Conclusions Based on the 2014 CCS algorithm, the “OAC not recommended” subgroup can have a high 1-year stroke rate overall, showing that such patients are not “low risk.” Use of the ESC guideline approach (based on the CHA2DS2-VASc) offers refinement of stroke risk stratification in such patients.
Source: Canadian Journal of Cardiology - January 17, 2015 Category: Cardiology Source Type: research

Elevated Levels of Serum Alkaline Phosphatase are Associated with Increased Risk of Cardiovascular Disease: A Prospective Cohort Study
CONCLUSIONS: Higher ALP levels, even within the normal range, were significantly associated with increased risks of CVD, in a dose-dependent manner. These findings suggested that regular monitoring of ALP levels may help in improving the early identification of the population at higher CVD risk.PMID:36261365 | DOI:10.5551/jat.63646
Source: Journal of Atherosclerosis and Thrombosis - October 19, 2022 Category: Cardiology Authors: Kang Liu Yanqiu Yu Yu Yuan Xuedan Xu Wenhui Lei Rundong Niu Miaoyan Shen Lue Zhou Rong Peng Qiuhong Wang Handong Yang Huan Guo Yang Ge Gang Liu Meian He Tangchun Wu Xiaomin Zhang Source Type: research

Prophylactic Efficacy and Safety of Antithrombotic Regimens in Patients with Stable Atherosclerotic Cardiovascular Disease (S-ASCVD): A Bayesian Network Meta-Regression Analysis
ConclusionsConsidering MACEs, myocardial infarction, all kinds of stroke, ischemic stroke, and major bleeding, low-dose aspirin plus rivaroxaban 2.5 mg twice daily should be considered the preferred regimen for S-ASCVD patients with low bleeding risk.
Source: American Journal of Cardiovascular Drugs - March 3, 2023 Category: Cardiology Source Type: research

Antithrombotic therapy for atrial fibrillation and coronary artery disease in older patients
Conclusions Among older patients with AF and CAD, overall warfarin use was low. Patients ≥80 years old at highest stroke risk received warfarin in similar proportions to the overall cohort. Further investigation into optimizing antithrombotic strategies in this population is warranted.
Source: American Heart Journal - October 20, 2014 Category: Cardiology Source Type: research

A risk assessment tool incorporating new biomarkers for cardiovascular events in acute coronary syndromes: the Organization to Assess Strategies in Ischemic Syndromes (OASIS) risk score
Conclusions The addition of NT-proBNP and hemoglobin A1C to 5 standard variables creates a 7-variable risk score that improves prediction of cardiovascular events at 1 year and aids in risk-based selection of NSTEACS patients for dual antiplatelet therapy. Teaser Several new biomarkers improve risk stratification in non-ST-segment elevation ACS, however they are not integrated into risk prediction tools. A risk score to predict CV death/MI/stroke was developed by incorporating new biomarkers with standard variables. The addition of NT-proBNP and hemoglobin A1C to 5 standard variables (age, prior MI/stroke, sex, ST-segment ...
Source: Canadian Journal of Cardiology - February 3, 2016 Category: Cardiology Source Type: research