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Total 77 results found since Jan 2013.

Medicare Patients with Symptomatic Carotid Disease Requiring Carotid Revascularization Are Likely to Have Delayed Access: An Analysis of a Multicenter Surgical Data
The Society for Vascular Surgery clinical practice guidelines for management of extracranial cerebrovascular disease recommends carotid revascularization as soon as the patient is neurologically stable after 48  hours and before 14 days of symptom onset in patients with recent stroke. In the United States, insurance status has been demonstrated to play a role in wait times for surgical care. There are no large-scale studies that assess the effect of patient primary insurance status on time to surgery in patients with symptomatic carotid disease.
Source: Journal of Vascular Surgery - May 23, 2023 Category: Surgery Authors: Daniel Willie-Permor, Gabriela Sendek, Marjan Moghaddam, Sina Zarrintan, Mahmoud Malas Tags: Poster Competition Source Type: research

Economic Outcomes of Transcatheter Versus Surgical Aortic Valve Replacement in Patients with Severe Aortic Stenosis and Low Surgical Risk: Results from the PARTNER 3 Trial
CONCLUSIONS: For patients with severe aortic stenosis and low surgical risk similar to those enrolled in the PARTNER 3 trial, transfemoral TAVR with the SAPIEN 3 valve is cost saving compared with SAVR at 2 years and is projected to be economically attractive in the long run as long as there are no substantial differences in late death between the 2 strategies. Long-term follow-up will be critical to ultimately determine the preferred treatment strategy for low-risk patients from both a clinical and economic perspective.PMID:37154049 | DOI:10.1161/CIRCULATIONAHA.122.062481
Source: Circulation - May 8, 2023 Category: Cardiology Authors: Benjamin Z Galper Khaja M Chinnakondepalli Kaijun Wang Elizabeth A Magnuson Michael Lu Vinod H Thourani Susheel Kodali Raj Makkar Howard C Herrmann Samir Kapadia Mathew Williams John Webb Craig R Smith Michael J Mack Martin B Leon David J Cohen PARTNER In Source Type: research

Reply: Stentless versus stented bioprosthetic root replacement in the medicare population and the wisdom of crowds
In our recent analysis of long-term outcomes of aortic root operations in the United States among Medicare beneficiaries using the Society of Thoracic Surgeons Adult Cardiac Surgery Database (STS-ACSD) and Centers for Medicare and Medicaid Services linked data for patients aged 65 years or older undergoing elective aortic root surgery, we concluded that the bioprosthetic Bentall operation should be the procedure of choice in this population due to improved survival and lower stroke risk compared with the use of the mechanical Bentall, and lower risk of aortic valve reintervention compared with valve-sparing aortic root replacement.
Source: The Journal of Thoracic and Cardiovascular Surgery - April 21, 2023 Category: Cardiovascular & Thoracic Surgery Authors: G. Chad Hughes Tags: Letter to the Editor Source Type: research

Reply from the authors: Stentless versus stented bioprosthetic root replacement in the medicare population and the wisdom of crowds
In our recent analysis of long-term outcomes of aortic root operations in the United States among Medicare beneficiaries using the Society of Thoracic Surgeons Adult Cardiac Surgery Database (STS-ACSD) and Centers for Medicare and Medicaid Services linked data for patients aged 65 years or older undergoing elective aortic root surgery, we concluded that the bioprosthetic Bentall operation should be the procedure of choice in this population due to improved survival and lower stroke risk compared with the use of the mechanical Bentall, and lower risk of aortic valve reintervention compared with valve-sparing aortic root replacement.
Source: The Journal of Thoracic and Cardiovascular Surgery - April 21, 2023 Category: Cardiovascular & Thoracic Surgery Authors: G. Chad Hughes Tags: Adult: Aorta: Letters to the Editor Source Type: research

2023 Alzheimer's disease facts and figures
This article describes the public health impact of Alzheimer's disease, including prevalence and incidence, mortality and morbidity, use and costs of care, and the overall impact on family caregivers, the dementia workforce and society. The Special Report examines the patient journey from awareness of cognitive changes to potential treatment with drugs that change the underlying biology of Alzheimer's. An estimated 6.7 million Americans age 65 and older are living with Alzheimer's dementia today. This number could grow to 13.8 million by 2060 barring the development of medical breakthroughs to prevent, slow or cure AD. Off...
Source: The Journal of Alzheimers Association - March 15, 2023 Category: Psychiatry Source Type: research

Background rates of adverse events of special interest for COVID-19 vaccine safety monitoring in the United States, 2019-2020
CONCLUSION: AESI background rates varied by database and demographics and fluctuated in March-December 2020, but most returned to pre-pandemic levels after May 2020. It is critical to standardize demographics and consider seasonal and other trends when comparing historical rates with post-vaccination AESI rates in the same database to evaluate COVID-19 vaccine safety.PMID:36404170 | DOI:10.1016/j.vaccine.2022.11.003
Source: Vaccine - November 20, 2022 Category: Allergy & Immunology Authors: Keran Moll Bradley Lufkin Kathryn R Fingar Cindy Ke Zhou Ellen Tworkoski Chianti Shi Shayan Hobbi Mao Hu Minya Sheng Jillian McCarty Shanlai Shangguan Timothy Burrell Yoganand Chillarige Jeff Beers Patrick Saunders-Hastings Stella Muthuri Kathryn Edwards Source Type: research

Janssen ’s Save Legs. Change Lives.™ is Creating a More Equitable Future for Communities at Risk of PAD-Related Amputations
TITUSVILLE, NJ, November 4, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced the first impact summary for its Save Legs. Change Lives.™ Spot Peripheral Artery Disease Now multi-year initiative, designed to create urgency and action around the hidden threat of peripheral artery disease (PAD)-related amputation. In its inaugural year, Save Legs. Change Lives.™ focused on reaching Black Americans, who are up to four times more likely than white Americans to have a PAD-related amputation.1 With this critical initiative, Janssen is focused on helping those at risk of PAD through more th...
Source: Johnson and Johnson - November 4, 2022 Category: Pharmaceuticals Tags: Latest News Source Type: news

Risk of stroke/systemic embolism, major bleeding and associated costs in non-valvular atrial fibrillation patients who initiated apixaban, dabigatran, or rivaroxaban compared with warfarin in the United States Medicare population: updated analysis
CONCLUSIONS: This real-world analysis showed DOACs to be associated with lower risk of stroke/SE and major bleeding, and lower medical costs compared to warfarin. Among them, only apixaban appears to be associated with a significantly lower risk of all three outcomes collectively: stroke/SE, major bleeding, and lower related medical costs compared to warfarin.PMID:35993487 | DOI:10.1080/03007995.2022.2115772
Source: Current Medical Research and Opinion - August 22, 2022 Category: Research Authors: Alpesh Amin Allison Keshishian Dionne M Hines Oluwaseyi Dina Hannah Le Lisa Rosenblatt Xianchen Liu Qisu Zhang Lien Vo Source Type: research

Oral anticoagulant underutilization among elderly patients with atrial fibrillation: insights from the United States Medicare database
ConclusionsAlthough OAC therapy prescription is the standard of care for stroke prevention in AF patients, its overall utilization is still low among Medicare patients  ≥ 65 years old, with specific patient characteristics that predict underutilization.
Source: Journal of Interventional Cardiac Electrophysiology - July 9, 2022 Category: Cardiology Source Type: research

PCR161 Updated Trends, Disparities, and Clinical Impact of Neuroimaging Utilization in Ischemic Stroke in the Medicare Population: 2012-2019
The purpose of this study was to update trends, investigate sociodemographic disparities, and evaluate the impact on mortality of stroke neuroimaging across the United States from 2012-2019.
Source: Value in Health - June 26, 2022 Category: International Medicine & Public Health Authors: J Wang, C Pelzl, A Boltyenkov, JM Katz, J Hemingway, E Christensen, E Rula, PC Sanelli Source Type: research