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Association of increased arterial stiffness with diastolic dysfunction in ischemic stroke patients: the Norwegian Stroke in the Young Study
Background: Young and middle-aged ischemic stroke survivors have a high prevalence of hypertension, increased arterial stiffness and abnormal left ventricular (LV) geometry, which all are associated with the presence of LV diastolic dysfunction. However, the prevalence and covariates of diastolic dysfunction in these patients have not been reported. Objectives: To explore diastolic dysfunction in ischemic stroke patients aged 15–60 years included in the Norwegian Stroke in the Young Study. Methods: Data from 260 patients with acute ischemic stroke was analyzed. Diastolic dysfunction was assessed by combining tran...
Source: Journal of Hypertension - February 7, 2020 Category: Cardiology Tags: ORIGINAL PAPERS: Organ damage Source Type: research

Prevalence of atherosclerosis and association with 5-year outcome: The Norwegian Stroke in the Young Study
CONCLUSION: Atherosclerosis is highly prevalent even in young stroke patients. Some areas and increasing NAA are associated with CVEs and death.PMID:35342817 | PMC:PMC8948509 | DOI:10.1177/23969873211059472
Source: Atherosclerosis - March 28, 2022 Category: Cardiology Authors: Beenish Nawaz Annette Fromm Halvor Øygarden Geir E Eide Sahrai Saeed Rudy Meijer Michiel L Bots Kristin M Sand Lars Thomassen Halvor N æss Ulrike Waje-Andreassen Source Type: research

Covariables and types of abnormal left ventricular geometry in nonelderly ischemic stroke survivors: the Norwegian Stroke in the Young Study
Background: Abnormal left ventricular (LV) geometry types, like LV hypertrophy (LVH) and concentric remodelling, are independently associated with impaired prognosis in hypertension. Little is known about the prevalence and covariables of abnormal LV geometry types in younger ischemic stroke patients. Methods: We used clinical and echocardiographic data from 280 patients aged 15–60 years included in the Norwegian Stroke in the Young Study. LVH was defined as LV mass index greater than 46.7 g/m2.7 in women and greater than 49.2 g/m2.7 in men. Concentric remodelling was considered present if posterior wall thickne...
Source: Journal of Hypertension - September 1, 2018 Category: Cardiology Tags: ORIGINAL PAPERS: Organ damage Source Type: research

Left ventricular myocardial dysfunction in young and middle-aged ischemic stroke patients: the Norwegian stroke in the young study
Background: Hypertension is highly prevalent in ischemic stroke patients, but less is known about its impact on subclinical left ventricular (LV) dysfunction in such patients. Methods: Conventional and speckle tracking echocardiography was performed in 276 young (15–44 years) and middle-aged (45–60 years) ischemic stroke patients (mean age 50 ± 9 years, 66% men). Hypertension was defined as a history of hypertension, use of antihypertensive medications, persistently elevated blood pressure (BP) during hospitalization or elevated clinic BP (≥140/90 mmHg) and ambulatory BP (≥130/80 mmHg) at follow-up vi...
Source: Journal of Hypertension - February 1, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Heart Source Type: research

High ward occupancy, bedspacing, and 60  day mortality for patients with myocardial infarction, stroke, and heart failure
ConclusionsPatients with heart failure had higher risk of admission to alternate wards when home ward occupancy was high. These patients may be negatively affected by full wards.
Source: ESC Heart Failure - March 29, 2022 Category: Cardiology Authors: Andreas Asheim, Sara Marie Nilsen, Stina Aam, Kjartan Sarheim Anthun, Fredrik Carlsen, Imre Janszky, Lars Johan Vatten, Johan H åkon Bjørngaard Tags: Original Article Source Type: research

Vascular risk factors and staging of atherosclerosis in patients and controls: The Norwegian Stroke in the Young Study
CONCLUSION: Vascular risk factors are highly prevalent in young- and middle-aged patients and controls, and are predictors of established atherosclerosis at study inclusion. Focus on main modifiable vascular RFs in primary prevention, and early and aggressive secondary treatment of patients are necessary to reduce further progression of atherosclerosis.PMID:36082261 | PMC:PMC9446327 | DOI:10.1177/23969873221098582
Source: Atherosclerosis - September 9, 2022 Category: Cardiology Authors: Beenish Nawaz Annette Fromm Halvor Øygarden Geir Egil Eide Sahrai Saeed Rudy Meijer Michiel L Bots Kristin Modalsli Sand Lars Thomassen Halvor N æss Ulrike Waje-Andreassen Source Type: research

Effectiveness and safety of oral anticoagulants in elderly patients with atrial fibrillation
Conclusion In this nationwide cohort study of patients ≥75 years initiating oral anticoagulation for AF, standard and reduced dose NOACs were associated with similar risks of stroke/SE as warfarin and lower or similar risks of bleeding. The NOACs seem to be a safe option also in elderly patients.
Source: Heart - February 16, 2022 Category: Cardiology Authors: Rutherford, O.-C. W., Jonasson, C., Ghanima, W., Söderdahl, F., Halvorsen, S. Tags: Open access Arrhythmias and sudden death Source Type: research

Blood pressure in professional male football players in Norway
Conclusion: Although the prevalence of high BP in professional football players was low, our data indicate a novel association between elevated BP and reduced arterial compliance, increased left ventricle mass and left atrium volume even in young athletes. This emphasizes closer focus on BP measurements and standardized follow-up after preparticipation screening of athletes.
Source: Journal of Hypertension - March 9, 2013 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology Source Type: research

Diabetes severity and the role of leisure time physical exercise on cardiovascular mortality: the Nord-Trlatin small letter o with strokendelag Health study (HUNT), Norway
Conclusions: The data suggest a more favourable effect of exercise in people with diabetes who used medication than in those who did not, suggesting that physical exercise should be encouraged as a therapeutic measure additional to medical treatment.
Source: Cardiovascular Diabetology - June 6, 2013 Category: Cardiology Authors: Børge MoeLiv Berit AugestadTom Nilsen Source Type: research

Abstract P279: Mapping of Chromosome 2 Differentially Expressed Aortic Genes Linked to Vascular Inflammation Using Congenic Rats Fed a High-salt Diet Session Title: Onsite Poster Competition II
Background: Three congenic rat strains (SB2a, SB2b and SB2e) were created by chromosome (Chr) 2 fragment introgression from normotensive Brown Norway (BN) rats into hypertensive Dahl salt sensitive (SS) background. SB2a and SB2b rats fed a normal-salt diet presented reduced blood pressure (BP) and inflammation when compared to SS rats. We hypothesized that BN-Chr2 contains antihypertensive and anti-inflammatory genes that could prevent high-salt diet (HSD)-induced BP elevation and vascular injury in SB2a and SB2b rats. These genes will be identified using microRNA (miRNA) and total RNA expression profiling analysis in aort...
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Olga Berillo, Sofiane Ouerd, Ku-Geng Huo, Chantal Richer, Daniel Sinnett, Anne E Kwitek, Pierre Paradis, Ernesto L Schiffrin Tags: Poster Abstract Presentations Source Type: research

Serum content of saturated fatty acids and the prevalence of atrial fibrillation - A norwegian cross-sectional study
Aim: Atrial fibrillation [AF] is a common cardiac arrhythmia with serious clinical consequences including a 5-fold higher risk of ischemic stroke. Serum content of saturated fatty acids (SFA) consisting of palmitic (C16:0) and stearic (C18:0) acid may be associated with the prevalence of AF.
Source: Atherosclerosis - August 1, 2018 Category: Cardiology Authors: P. Dinesen, S. Tveit, A. Kalstad, P. Myhre, K. Laake, S. Solheim, H. Arnesen, E.B. Schmidt, S. Lundbye-Christensen, I. Seljeflot Source Type: research

The Integration of Doppler Ultrasound With Two-Dimensional Echocardiography and the Noninvasive Cardiac Hemodynamic Revolution of the 1980s
In the 1970s, as cardiac imaging matured from M-mode to two-dimensional echocardiography, investigators in Norway showed that continuous-wave Doppler ultrasonography could be used to accurately measure the mean gradient and pressure half-time for stenotic mitral valves. In the 1980s, continuous-wave Doppler was validated for measurement of the pressure gradient across stenotic aortic valves, and pulsed-wave Doppler combined with two-dimensional echocardiographic imaging was validated for noninvasive measurement of stroke volume and cardiac output.
Source: Journal of the American Society of Echocardiography - October 16, 2018 Category: Cardiology Authors: Fletcher A. Miller Source Type: research

Validation of the cardiovascular risk model NORRISK 2 in South Asians and people with diabetes.
Conclusions. The NORRISK 2-SADia model improved predictions of CVD substantially in South Asians, whose risks were underestimated by the NORRISK 2 model. The NORRISK 2-SADia model may facilitate more intense preventive measures in this high-risk population. PMID: 33073627 [PubMed - as supplied by publisher]
Source: Scandinavian Cardiovascular Journal - October 20, 2020 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Screen-Detected Atrial Fibrillation and “Micro-Atrial Fibrillation” and Risk of Cardiovascular Events after Myocardial Infarction in Elderly Patients
Conclusions: Two-week intermittent ECG screening identified few cases of new-onset AF but a substantial number of patients with “micro-AF.” “Micro-AF” was associated with an increased risk of major cardiovascular events, albeit with an intermediate risk compared to those with new-onset AF.
Source: Cardiology - December 20, 2022 Category: Cardiology Source Type: research