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Total 585 results found since Jan 2013.

Use of low-dose quetiapine increases the risk of major adverse cardiovascular events: results from a nationwide active comparator-controlled cohort study
World Psychiatry. 2022 Oct;21(3):444-451. doi: 10.1002/wps.21010.ABSTRACTAt standard doses used for schizophrenia or bipolar disorder, quetiapine has been associated with weight gain and increased levels of triglycerides, to-tal cholesterol and low-density lipoprotein (LDL) cholesterol, which are risk factors for cardiovascular morbidity and mortality. However, this drug is also commonly used off-label at low doses for anxiolytic or hypnotic purposes, and its cardiovascular safety at these doses is unknown. We aimed to assess the risk of major adverse cardiovascular events with use of low-dose quetiapine compared to use of...
Source: World Psychiatry - September 8, 2022 Category: Psychiatry Authors: Mikkel H øjlund Kjeld Andersen Martin T Ernst Christoph U Correll Jesper Hallas Source Type: research

Does coffee make you live longer?
Conclusion This study, conducted on a large number of people across Europe, was backed up by similar findings in the US. It appears to show some association between people who drink higher amounts of coffee and a reduced risk of death. But the "potentially beneficial clinical implications" need to be considered carefully for a number of reasons: Although the analyses were adjusted for some confounding variables, there may be a number of other factors that differ between the groups that account for the differences in death, such as socioeconomic status, family history, other medical conditions, and use of medic...
Source: NHS News Feed - July 12, 2017 Category: Consumer Health News Tags: Food/diet Source Type: news

Cardiovascular mortality and morbidity in patients with type 2 diabetes following initiation of sodium-glucose co-transporter-2 inhibitors versus other glucose-lowering drugs (CVD-REAL Nordic): a multinational observational analysis
Publication date: Available online 3 August 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Kåre I Birkeland, Marit E Jørgensen, Bendix Carstensen, Frederik Persson, Hanne L Gulseth, Marcus Thuresson, Peter Fenici, David Nathanson, Thomas Nyström, Jan W Eriksson, Johan Bodegård, Anna Norhammar Background In patients with type 2 diabetes and a high cardiovascular risk profile, the sodium-glucose co-transporter-2 (SGLT2) inhibitors empagliflozin and canagliflozin have been shown to lower cardiovascular morbidity and mortality. Using real-world data from clinical practice, we aimed to compare cardiovas...
Source: The Lancet Diabetes and Endocrinology - August 4, 2017 Category: Endocrinology Source Type: research

Compliance with accreditation and recommended hospital care —a Danish nationwide population-based study
ConclusionHigh compliance with accreditation standards was associated with a higher level of evidence-based hospital care in Danish hospitals.
Source: International Journal for Quality in Health Care - August 22, 2017 Category: International Medicine & Public Health Source Type: research

Educational inequality in cardiovascular diseases: a sibling approach.
CONCLUSIONS: Confounding from factors shared by siblings explained the associations between education and the cardiovascular disease outcomes but to varying degrees. This should be taken into account when planning interventions aimed at reducing educational inequalities in the development of cardiovascular disease, ischaemic heart disease and stroke. PMID: 28992724 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Public Health - October 1, 2017 Category: International Medicine & Public Health Authors: Søndergaard G, Dalton SO, Mortensen LH, Osler M Tags: Scand J Public Health Source Type: research

Higher Risk of Vascular Dementia in Myocardial Infarction Survivors.
Conclusions -MI was associated with higher risk of vascular dementia throughout follow-up and this asssociation was stronger in patients suffering stroke. The risk of Alzheimer's disease and other dementias was not higher in MI patients. PMID: 29025764 [PubMed - as supplied by publisher]
Source: Circulation - October 12, 2017 Category: Cardiology Authors: Sundbøll J, Hováth-Puhó E, Adelborg K, Schmidt M, Pedersen L, Bøtker HE, Henderson VW, Sørensen HT Tags: Circulation Source Type: research

Compliance with accreditation and recommended hospital care —a Danish nationwide population-based study
ConclusionHigh compliance with accreditation standards was associated with a higher level of evidence-based hospital care in Danish hospitals.
Source: International Journal for Quality in Health Care - August 22, 2017 Category: International Medicine & Public Health Source Type: research

Type 1 versus type 2 diabetes and thromboembolic risk in patients with atrial fibrillation: A Danish nationwide cohort study
Atrial fibrillation is a common cause of stroke, and diabetes increases stroke risk. Stroke risk may vary depending on the type of diabetes. We investigated whether type 1 and type 2 diabetes are associated with different risks of thromboembolism among patients with atrial fibrillation.
Source: International Journal of Cardiology - July 22, 2018 Category: Cardiology Authors: Mia V. Fangel, Peter B. Nielsen, Torben B. Larsen, Bo Christensen, Thure F. Overvad, Gregory Y.H. Lip, Samuel Z. Goldhaber, Martin B. Jensen Source Type: research

Should the Presence or Extent of Coronary Artery Disease be Quantified in the CHA2DS2-VASc Score in Atrial Fibrillation? A Report from the Western Denmark Heart Registry.
CONCLUSION:  Presence, but not extent, of CAD was an independent risk factor of the composite thromboembolic endpoint beyond the components already included in the CHA2DS2-VASc score. Consequently, we suggest that significant angiographically proven CAD should be included in the vascular disease criterion in the CHA2DS2-VASc score. PMID: 30419601 [PubMed - as supplied by publisher]
Source: Thrombosis and Haemostasis - November 12, 2018 Category: Hematology Authors: Steensig K, Olesen KKW, Thim T, Nielsen JC, Jensen SE, Jensen LO, Kristensen SD, Bøtker HE, Lip GYH, Maeng M Tags: Thromb Haemost Source Type: research

Impact of Male Origin Microchimerism on Cardiovascular Disease in Women: A Prospective Cohort Study.
Abstract Increasing parity is associated with an increased risk of ischemic heart disease (IHD) and stroke in women. This is likely attributed to biological responses of pregnancy. Male cells of presumed fetal origin are commonly present in women years after pregnancy-a phenomenon termed male origin microchimerism. Here, we investigated whether male origin microchimerism was associated with risk of IHD and ischemic stroke in women. We evaluated the association between male origin microchimerism and ischemic events in a cohort of 766 Danish women enrolled in the Diet, Cancer and Health cohort during 1993-1997 when ...
Source: Am J Epidemiol - November 13, 2020 Category: Epidemiology Authors: Hallum S, Gerds TA, Sehested TSG, Jakobsen MA, Tjønneland A, Kamper-Jørgensen M Tags: Am J Epidemiol Source Type: research

Impact of Male-Origin Microchimerism on Cardiovascular Disease in Women: A Prospective Cohort Study
In this study, we investigated whether MOM was associated with risk of IHD and ischemic stroke in women. We evaluated the association between MOM and ischemic events in a cohort of 766 Danish women enrolled in the Diet, Cancer and Health cohor t during 1993–1997 when aged 50–64 years. Of these women, 545 (71.2%) tested positive for MOM through targeting of the Y chromosome (DYS14 DNA sequence) in their blood. Multiple Cox regression models were used to calculate hazard ratios with 95% confidence intervals. We found that MOM was associated with a significantly reduced rate of IHD (hazard ratio  = 0.44, 95% confidence ...
Source: American Journal of Epidemiology - November 13, 2020 Category: Epidemiology Source Type: research