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Vaccination: Veterinary Vaccinations
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A qualitative exploratory study using One Health approach for developing an intervention package for elimination of human anthrax in an endemic district of Odisha, India
CONCLUSIONS: The coordination gaps, financial burden, insufficient relevant knowledge and information among the concerned stakeholders were the issues found in this study in addition to non-availability of proper diagnostic facility. The coordination among different departments adapting One Health approach may be one of the best possible ways for the elimination of anthrax cases in an endemic region.PMID:33907004 | DOI:10.4103/ijmr.IJMR_646_21
Source: The Indian Journal of Medical Research - April 28, 2021 Category: Biomedical Science Authors: Asit Mansingh Hari Ram Choudhary Jyoti Shandilya Debdutta Bhattacharya Jaya Singh Kshatri Debaprasad Parai Matrujyoti Pattanaik Arun Kumar Padhi Hitesh Kumar Jain Prasantajyoti Mohanty Srikanta Kanungo Sanghamitra Pati Source Type: research
The Epidemiology and Variation in Pseudorabies Virus: A Continuing Challenge to Pigs and Humans
Viruses. 2022 Jul 1;14(7):1463. doi: 10.3390/v14071463.ABSTRACTPseudorabies virus (PRV) can infect most mammals and is well known for causing substantial economic losses in the pig industry. In addition to pigs, PRV infection usually leads to severe itching, central nervous system dysfunction, and 100% mortality in its non-natural hosts. It should be noted that increasing human cases of PRV infection have been reported in China since 2017, and these patients have generally suffered from nervous system damage and even death. Here, we reviewed the current prevalence and variation in PRV worldwide as well as the PRV-caused in...
Source: Herpes - July 27, 2022 Category: Infectious Diseases Authors: Qingyun Liu Yan Kuang Yafei Li Huihui Guo Chuyue Zhou Shibang Guo Chen Tan Bin Wu Huanchun Chen Xiangru Wang Source Type: research
Hepatitis Research Aided By New Rodent Viruses
Newly discovered mouse viruses could pave the way for future progress in hepatitis research, enabling scientists to study human disease and vaccines in the ultimate lab animal. In a study to be published in mBio®, the online open-access journal of the American Society for Microbiology, scientists describe their search for viruses related to the human hepatitis C virus (HCV) and human pegiviruses (HPgV) in frozen stocks of wild mice...
Source: Health News from Medical News Today - April 11, 2013 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news
Identification of a protective protein from stationary phase exoproteome of Brucella abortus
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Source: FEMS Immunology and Medical Microbiology - August 3, 2013 Category: Microbiology Authors: Shikha Jain, Subodh Kumar, Sudhir Dohre, Prachiti Afley, Nabonita Sengupta, Syed Imteyaz Alam Tags: Research Paper Source Type: research
Identification of a protective protein from stationary‐phase exoproteome of Brucella abortus
Abstract
Brucellosis is a worldwide zoonotic disease. No Brucella vaccine is available for use in humans, and existing animal vaccines have limitations. To search the putative vaccine candidates, we studied the exoproteome of Brucella abortus NCTC 10093 using 2‐DE–MS approach. Twenty‐six proteins were identified using MALDI‐TOF/TOF tandem mass spectrometry. Outer membrane protein 25, d‐galactose periplasmic‐binding protein, oligopeptide ABC transporter protein and isopropylmalate synthase were found to be the most abundant proteins. Most proteins (6, 23%) were predicted to be involved in amino acid transport an...
Source: FEMS Immunology and Medical Microbiology - August 14, 2013 Category: Microbiology Authors: Shikha Jain, Subodh Kumar, Sudhir Dohre, Prachiti Afley, Nabonita Sengupta, Syed I. Alam Tags: Research Article Source Type: research
Evaluation of the immunogenicity and protective efficacy of Killed Leishmania donovani antigen along with different adjuvants against experimental visceral leishmaniasis
Abstract
Visceral leishmaniasis (VL) caused by Leishmania donovani is a life-threatening disease involving uncontrolled parasitization of vital organs. Drugs to treat leishmaniasis have one or more limitations or insufficiencies in the long run. A safe and efficacious vaccine to control this disease is needed. Killed antigens that could be safer as vaccines have shown limited efficacy in clinical trials. Immunogenic enhancement with appropriate adjuvants may thus be required to elicit protective immunity based on antibodies and effector T-cell functions. Therefore, it is essential to search for adjuvant to enhance...
Source: Medical Microbiology and Immunology - November 29, 2014 Category: Microbiology Source Type: research
An update on novel COVID-19 pandemic: a battle between humans and virus.
Authors: Prajapati S, Sharma M, Kumar A, Gupta P, Narasimha Kumar GV
Abstract
In the 21st century, human civilization has witnessed three major epidemics caused by Coronaviruses namely severe acute respiratory syndrome coronavirus (SARS CoV) in 2003, Middle East respiratory syndrome coronavirus (MERS CoV) in 2012 and 2019 novel coronavirus (2019 nCoV) or coronavirus disease (COVID 19) in 2019. Among these, COVID-19 has greater transmission and mortality rate. 2019 nCoV belongs to a large family of positive sense single-stranded RNA viruses (+ssRNA) that can be isolated in different animal species. The most communal...
Source: European Review for Medical and Pharmacological Sciences - June 5, 2020 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Comparison of the immunogenicity & protective efficacy of various SARS-CoV-2 vaccine candidates in non-human primates.
Comparison of the immunogenicity & protective efficacy of various SARS-CoV-2 vaccine candidates in non-human primates.
Indian J Med Res. 2020 Dec 23;:
Authors: Mukhopadhyay L, Yadav PD, Gupta N, Mohandas S, Patil DY, Shete-Aich A, Panda S, Bhargava B
Abstract
Background & objectives: The COVID-19 pandemic has emerged as a global public health crisis and research groups worldwide are engaged in developing vaccine candidates to curb its transmission, with a few vaccines having progressed to advanced stages of clinical trials. The aim of this systematic review was to compare immunogenicity and pr...
Source: The Indian Journal of Medical Research - December 23, 2020 Category: Biomedical Science Authors: Mukhopadhyay L, Yadav PD, Gupta N, Mohandas S, Patil DY, Shete-Aich A, Panda S, Bhargava B Tags: Indian J Med Res Source Type: research
Lassa fever: why there are more public health questions than answers
The Lassa virus can wipe out entire families. It is transmitted by rats and is endemic to west Africa – so why is there no vaccine? Lina Moses shares her experiences of working in Sierra LeoneI'm in a village in eastern Sierra Leone staring at a row of dead rats snared in branches, leaves and grass. The contraptions are called funnel traps, or tolei in the local Mende dialect. We're hoping these devices and other easily accessible or producible materials will lower the rodent populations in villages sufficiently to prevent Lassa fever.With a DfID-funded project called Wash (water, sanitation health), Facility Sierra Leon...
Source: Guardian Unlimited Science - February 21, 2013 Category: Science Tags: Guardian Professional World news Infectious diseases Malaria and infectious diseases Medical research Microbiology Sierra Leone Editorial Global development professionals network Policy and advocacy Africa Science Source Type: news
Common bacteria could help prevent food allergies
ConclusionThis research examined how normal populations of gut bacteria influence mouse susceptibility to peanut allergens. The findings suggest the Clostridia group of bacteria may have a particular role in altering the immune defenses of the gut lining and preventing some of the food allergen entering the bloodstream. The findings inform the theory that our increasingly sterile environments and increased use of antibiotics could lead to a reduction in our normal gut bacteria, which could possibly lead to people developing a sensitivity to allergens.But these findings are in the very early stages. So far, only mice have b...
Source: NHS News Feed - August 26, 2014 Category: Consumer Health News Tags: Food/diet Medical practice Source Type: news
Human brucellosis in pregnancy - an overview.
Authors: Bosilkovski M, Arapović J, Keramat F
Abstract
Human brucellosis during pregnancy is characterized by significantly less pronounced adverse obstetric outcomes than in animals, but with remarkably more adverse obstetric outcomes when compared to healthy pregnant women. Seroprevalence of brucellosis in pregnancy and cumulative incidence of brucellosis cases per 1000 delivered obstetrical discharges in endemic regions were reported to be 1.5-12.2% and 0.42-3.3, respectively. Depending on the region, frequency of pregnant women in the cohorts of patients with brucellosis was from 1.5% to 16.9%. The most common...
Source: Bosnian Journal of Basic Medical Sciences - December 1, 2019 Category: General Medicine Tags: Bosn J Basic Med Sci Source Type: research
5 Ways to Teach Kids (and Grownups) About Science
Few things make a science teacher happier than hearing a child call an idea weird. If you speak fluent child (and a good science teacher does), weird doesn’t mean what it usually means—odd, off-putting. It means interesting, mystifying and deeply, deeply cool.
Finding stuff weird was how Hakeem Oluseyi realized he was interested in science as a child. He liked dinosaurs, sure, but mostly the bizarre ones. The same was true for his fascination with modern animals, and the same was true too for his interest in space. Any kid can take a shine to planets and moons, but Oluseyi was also drawn to the through-the-look...
Source: TIME: Top Science and Health Stories - December 7, 2015 Category: Science Authors: Jeffrey Kluger Tags: Uncategorized Education Hakeem Oluseyi moons planets Science science education science literacy space stars teaching science Source Type: news
Vaccine donation supports search dogs
DOGS belonging to the Search and Rescue Dog Association (SARDA) England have received a free health check and vaccinations thanks to support from the veterinary corporate group CVS. The charity's dogs are all owned by their handlers and have recently completed a deployment helping in the parts of the UK that were hit by flooding over the winter, including Cumbria and Yorkshire. During their March national training weekend at the Castleshaw Outdoor Centre in Oldham, Vicky Weedon, a vet at the CVS practice West Mount Vets, gave all the dogs a health check and vaccinated them. Ms Weedon has a long-standing relationship with t...
Source: Veterinary Record - March 23, 2016 Category: Veterinary Research Tags: News and Reports Source Type: research
Transcriptomics of Haemophilus (Gl ässerella) parasuis serovar 5 subjected to culture conditions partially mimetic to natural infection for the search of new vaccine antigens
Haemophilus (Gl ässerella) parasuis is the etiological agent of Glässer’s disease in pigs. Control of this disorder has been traditionally based on bacterins. The search for alternative vaccines has focused mainly...
Source: BMC Veterinary Research - November 6, 2018 Category: Veterinary Research Authors: Álvaro Álvarez-Estrada, César B. Gutiérrez-Martín, Elías F. Rodríguez-Ferri and Sonia Martínez-Martínez Tags: Research article Source Type: research
