Lassa fever: why there are more public health questions than answers

The Lassa virus can wipe out entire families. It is transmitted by rats and is endemic to west Africa – so why is there no vaccine? Lina Moses shares her experiences of working in Sierra LeoneI'm in a village in eastern Sierra Leone staring at a row of dead rats snared in branches, leaves and grass. The contraptions are called funnel traps, or tolei in the local Mende dialect. We're hoping these devices and other easily accessible or producible materials will lower the rodent populations in villages sufficiently to prevent Lassa fever.With a DfID-funded project called Wash (water, sanitation health), Facility Sierra Leone, Tulane University and Kenema Government Hospital are working in 20 villages introducing Lassa fever education and rodent control training. For the project to be successful, we have to control one of the most ubiquitous rodents in sub-Saharan Africa, Mastomys natalensis — the multimammate rat.Lassa fever is common in this part of the country where the disease can wipe out entire households and cause panic throughout villages. The disease has a gradual onset of fever, aches and pains that are indistinguishable from malaria or typhoid — diseases as familiar to villagers as the common cold. For some, Lassa fever will progress from these non-specific symptoms to sore throat, facial oedema, haemorrhaging and death. Although Lassa fever and its severe consequences are well-known by residents in this region, fewer know the rat that commonly infest...
Source: Guardian Unlimited Science - Category: Science Tags: Guardian Professional World news Infectious diseases Malaria and infectious diseases Medical research Microbiology Sierra Leone Editorial Global development professionals network Policy and advocacy Africa Science Source Type: news

Related Links:

Publication date: Available online 3 June 2020Source: Carbohydrate PolymersAuthor(s): Zhenguang Liu, Lin Yu, Pengfei Gu, Ruonan Bo, Adelijiang Wusiman, Jiaguo Liu, Yuanlaing Hu, Deyun Wang
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
Authors: Ferella A, Aguirreburualde MSP, Sammarruco A, Parreño V, Santos MJD, Mozgovoj M Abstract Bovine respiratory syncytial virus (BRSV) is one of the most relevant agents responsible for respiratory disease in cattle from both dairy and beef farms. BRSV is spread by horizontal contact causing a constant presence of seropositive animals that favors viral circulation throughout the year. Moreover, reinfections with BRSV are frequent between animals regardless of their age as BRSV does not confer long-lasting protective immunity. Several studies have demonstrated the circulation of BRSV in cattle from diffe...
Source: Revista Argentina de Microbiologia - Category: Microbiology Tags: Rev Argent Microbiol Source Type: research
CONCLUSIONS: Immunization Information System is an essential technological innovation for the management of immunization actions. However, the production of timely records and the use of information are still challenges. Investments in training are required to ensure System's management and operationalization activities. PMID: 32490998 [PubMed - in process]
Source: Revista Brasileira de Enfermagem - Category: Nursing Authors: Tags: Rev Bras Enferm Source Type: research
[Thomson Reuters Foundation] Rome -Thursday's GAVI vaccine summit aims to help people in the developing world get access to any eventual coronavirus vaccine. What are the obstacles?
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
The GAVI vaccines alliance said on Thursday it had raised $8.8 billion from international donor governments, companies and philanthropic foundations to fund its immunisation programmes through to 2025.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
Novavax Inc said on Thursday the U.S. Department of Defense (DoD) will give the late-stage biotech company up to $60 million to fund the manufacturing of its experimental COVID-19 vaccine.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
A group of conservative U.S. doctors has sued the Food and Drug Administration for limiting use of the malaria drug hydroxychloroquine for COVID-19, arguing that the therapy should be made widely available to fight the pandemic.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
The director of the National Institutes of Health said Thursday he's concerned that vaccine "skepticism" could hinder the effort to immunize the country against Covid-19.
Source: - Health - Category: Consumer Health News Source Type: news
Authors: Kyrkoudis T, Tsoucalas G, Fiska A Abstract The choice of Dedeagatch as the place where the station of the Adrianoupolis-Constantinople railway line was to be built was the reason for the foundation of the Greek city of Alexandroupolis (originally under the Ottoman government). The population grew in its early years mainly due to the settlement by railway and construction workers. Meanwhile, poverty, poor hygiene and environmental conditions led to a series of epidemics and various sporadic cases of infections such as malaria, typhoid fever, scarlet fever and tubercolosis, infections which marked the early ...
Source: Infezioni in Medicina - Category: Infectious Diseases Tags: Infez Med Source Type: research
Authors: Meregildo ED Abstract Neurocysticercosis (NCC) is a global health problem. In more developed countries, NCC is mainly a disease affecting immigrants. In developing countries, NCC is the most common parasitic disease of the nervous system and the main cause of acquired epilepsy. NCC is also an unrecognized cause of strokes and could account for 4%-12% of strokes. Here, I report a case of a 58-year-old woman who presented to the emergency department (ED) with severe headache, vomiting, and sudden loss of consciousness. Multiple NCC and Fisher grade 4 aneurysmal subarachnoid hemorrhage (SAH) were demonstrated...
Source: Infezioni in Medicina - Category: Infectious Diseases Tags: Infez Med Source Type: research
More News: African Health | Centers for Disease Control and Prevention (CDC) | Common Cold | Education | Endemics | Environmental Health | Expenditures | Government | Health | Hospitals | Infectious Diseases | International Medicine & Public Health | Laboratory Medicine | Lassa Fever | Malaria | Malaria Vaccine | Men | Microbiology | Research | Rural Health | Science | Sierra Leone Health | Sore Throat | Training | Typhoid | Typhoid Vaccine | Universities & Medical Training | Vaccines | Veterinary Vaccinations