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Small-world network of patients with primary insomnia: a resting-state functional magnetic resonance imaging study
Nan Fang Yi Ke Da Xue Xue Bao. 2021 Mar 25;41(3):424-429. doi: 10.12122/j.issn.1673-4254.2021.03.16.ABSTRACTOBJECTIVE: To explore the changes of small-world network properties in patients with primary insomnia based on resting-state functional magnetic resonance imaging (rs-fMRI).OBJECTIVE: The rs-MRI data and neurological scale data of 65 patients and 60 matched healthy controls were collected. The brain network was constructed using GRENTA software. SPSS software and network-based statistical analysis methods were used for statistical analysis.OBJECTIVE: There was no significant difference between the two groups in terms...
Source: Journal of Southern Medical University - April 14, 2021 Category: Universities & Medical Training Authors: W Huang Z Li S Wu J Hong G Wen Source Type: research

Failure mode and effect analysis for linear accelerator-based paraspinal stereotactic body radiotherapy
CONCLUSIONS: A paraspinal SBRT workflow in a large clinic was evaluated using a multidisciplinary and systematic risk analysis, which led to feasible solutions to key root causes. Treatment planning was a major source of PFMs that systematically affect the safety and quality of treatments. Accurate evaluation of external treatment records remains a challenge.PMID:34708910 | DOI:10.1002/acm2.13455
Source: Journal of Applied Clinical Medical Physics - October 28, 2021 Category: Physics Authors: Sangkyu Lee Dale Michael Lovelock Alex Kowalski Kate Chapman Robert Foley Mary Gil Gerri Pastrana Daniel S Higginson Yoshiya Yamada Lei Zhang James Mechalakos Ellen Yorke Source Type: research

Assessment of artificial intelligence (AI) reporting methodology in glioma MRI studies using the Checklist for AI in Medical Imaging (CLAIM)
ConclusionAI may be a means of producing high-accuracy results for certain tasks in glioma MRI; however, there remain issues with reporting quality. AI reporting guidelines may aid in a more reproducible and standardised approach to reporting and will aid in clinical integration.
Source: Neuroradiology - February 7, 2023 Category: Radiology Source Type: research

Probing bundle-wise abnormalities in patients infected with human immunodeficiency virus using fixel-based analysis: new insights into neurocognitive impairments
CONCLUSIONS: Our study demonstrated the utility of FBA on detecting the WM alterations related to HIV infection. The bundle-wise FBA method provides a new perspective for investigating HIV-induced microstructural and macrostructural WM-related changes, which may help to understand cognitive dysfunction in HIV patients thoroughly.PMID:37605986 | DOI:10.1097/CM9.0000000000002829
Source: Chinese Medical Journal - August 22, 2023 Category: General Medicine Authors: Jing Zhao Bin Jing Jiaojiao Liu Feng Chen Ye Wu Hongjun Li Source Type: research

Frontoparietal activation during visual conjunction search: Effects of bottom ‐up guidance and adult age
Abstract We conducted functional magnetic resonance imaging (fMRI) with a visual search paradigm to test the hypothesis that aging is associated with increased frontoparietal involvement in both target detection and bottom‐up attentional guidance (featural salience). Participants were 68 healthy adults, distributed continuously across 19 to 78 years of age. Frontoparietal regions of interest (ROIs) were defined from resting‐state scans obtained prior to task‐related fMRI. The search target was defined by a conjunction of color and orientation. Each display contained one item that was larger than the others (i.e., a s...
Source: Human Brain Mapping - January 3, 2017 Category: Neurology Authors: David J. Madden, Emily L. Parks, Catherine W. Tallman, Maria A. Boylan, David A. Hoagey, Sally B. Cocjin, Micah A. Johnson, Ying ‐hui Chou, Guy G. Potter, Nan‐kuei Chen, Lauren E. Packard, Rachel E. Siciliano, Zachary A. Monge, Michele T. Diaz Tags: Research Article Source Type: research

Changes in neural activation underlying attention processing of emotional stimuli following treatment with positive search training in anxious children
Publication date: Available online 11 March 2018 Source:Journal of Anxiety Disorders Author(s): Allison M. Waters, Yuan Cao, Rachel Kershaw, Georg M. Kerbler, David H.K. Shum, Melanie J. Zimmer-Gembeck, Michelle G. Craske, Brendan P. Bradley, Karin Mogg, Daniel S. Pine, Ross Cunnington Prior research indicates that positive search training (PST) may be a promising home-based computerised treatment for childhood anxiety disorders. It explicitly trains anxious individuals in adaptive, goal-directed attention-search strategies to search for positive and calm information and ignore goal-irrelevant negative cues. Although PST ...
Source: Journal of Anxiety Disorders - March 12, 2018 Category: Psychiatry Source Type: research

Brain network connectivity mediates education-related cognitive performance in healthy elderly adults.
CONCLUSIONS: Our findings indicate that inhibitory modulation in the resting-state brain networks related to complex cognition is one of the main routes through which education exerts its protective effects on cognition in normal aging. PMID: 30345918 [PubMed - as supplied by publisher]
Source: Current Alzheimer Research - October 21, 2018 Category: Neurology Authors: Chen Y, Qi D, Qin T, Chen K, Ai M, Li X, Li H, Zhang J, Mao H, Yang Y, Zhang Z Tags: Curr Alzheimer Res Source Type: research

Imaging in systemic amyloidosis
Background Diagnosis of systemic amyloidosis remains challenging. Histology, the current gold standard for diagnosis of amyloidosis provides limited information on the extent of the disease and is not useful for monitoring. Non-invasive imaging modalities offer an easy way to evaluate whole-body amyloid burden, accurately identify organ involvement, quantify and monitor disease progression and response to treatment. Sources of data A literature search was performed using PubMed on the subjects of ‘amyloid imaging’, ‘SAP scintigraphy’, ‘imaging in cardiac amyloidosis’, ‘cardiac MRI...
Source: British Medical Bulletin - September 3, 2013 Category: Journals (General) Authors: Sachchithanantham, S., Wechalekar, A. D. Tags: Nuclear Medicine Articles Source Type: research