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Procedure: Liver Transplant

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Total 226 results found since Jan 2013.

UCLA awarded $11.5 million to improve organ, hand and face transplantation
The Dumont –UCLA Transplant Center has received two grants totaling $11.5 million from the federal government for research aimed at making donated organs last longer and helping transplant recipients live longer, healthier lives.The grant projects — one funded by the National Institutes of Health and the other by the Department of Defense — focus specifically on improving outcomes in liver transplantation and in hand and face transplantation.Both initiatives are led by Dr. Jerzy Kupiec-Weglinski, UCLA ’s Paul I. Terasaki Professor of Surgery and vice chair of basic research in the surgery department at theDavid Gef...
Source: UCLA Newsroom: Health Sciences - July 29, 2022 Category: Universities & Medical Training Source Type: news

Mycophenolate Mofetil Use Is Associated With Reduced Incidence of Food Allergy in Liver Transplanted Children
Conclusions: Use of MMF 1 and 2 years after transplantation was associated with less food allergy and sensitization against food allergens. The effect of MMF was not due to reduced trough levels of tacrolimus.
Source: Journal of Pediatric Gastroenterology and Nutrition - July 28, 2022 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

18FFDG PET/MRI in the follow-up of hepatocellular carcinoma after liver transplantation
Conclusions PET/MRI is useful for oncological surveillance of patients who have undergone liver transplantation for HCC, particularly in cases of allergy to contrast media, renal failure or persistently elevated alpha-fetoprotein levels, and with no identification of metastatic/relapsing foci at standard-of-care imaging.
Source: Nuclear Medicine Communications - February 10, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Impact of Prior Drug Allergies on the Risk, Clinical Features, and Outcomes of Idiosyncratic Drug-Induced Liver Injury in Adults
ConclusionA prior drug allergy history was not associated with a greater likelihood of developing DILI compared to other causes of acute liver injury. However, the probable DILI patients with a history of prior drug allergy tended to have less severe liver injury and clinical outcomes. The low rate of suspect drug documentation in the “Drug Allergy” section of EMR after a DILI episode is of concern and could lead to avoidable harm from inadvertent suspect drug re-challenge.
Source: Digestive Diseases and Sciences - February 4, 2022 Category: Gastroenterology Source Type: research

De Novo Food Allergy in Pediatric Recipients of Liver Transplant
Allergic and atopic conditions, including food allergy, asthma, eczema and eosinophilic disease of the gastrointestinal tract after liver transplant in previously non-allergic children have been increasingly described. After a liver transplant, children can present mild to severe reactions to food allergens (ie, from urticaria-angioedema to life-threatening anaphylactic reactions). De novo post-transplant food allergy may become clinically evident in children who undergo liver transplant between a few months and a few years of transplant. The present narrative review aims to describe the spectrum of de novo post-transplant...
Source: Journal of Pediatric Gastroenterology and Nutrition - February 1, 2022 Category: Gastroenterology Tags: Topic of the Month Source Type: research

M264 hypereosinophilia, eosinophilic endocardial infiltrates, heart failure, and liver mass in a toddler with heart transplant
Hypereosinophilia in pediatric patients with heart transplant have been infrequently described (1). Most cases are related to allograft rejection (2), with other etiologies rarely reported.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2021 Category: Allergy & Immunology Authors: H. Haq, B. Ariue Source Type: research

P090 balance of b-cell populations in pediatric solid-organ transplant recipients associated with infection risk
Long-term immunosuppression in patients receiving kidney or liver allografts results in increased risk of infection. We seek to examine underlying immunologic laboratory parameters associated with infection risk.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2021 Category: Allergy & Immunology Authors: B. Geng, C. Collins, L. Loop, S. Ozog, C. Anterasian, C. Ripp, K. Newton, E. Ingulli Tags: Clinical Immunology, Immunodeficiency Source Type: research

International retrospective study of allogeneic hematopoietic cell transplantation for activated PI3K-delta syndrome
CONCLUSIONS: Graft failure, graft instability and poor graft function requiring unplanned donor cell infusion were major barriers to successful HCT. Post-HCT mTORi use may confer an advantage to residual host cells, promoting graft instability. Longer term post-HCT follow-up of more patients is needed to elucidate the kinetics of immune reconstitution and donor chimerism, establish approaches that reduce graft instability, and assess the completeness of phenotype reversal over time.PMID:34033842 | DOI:10.1016/j.jaci.2021.04.036
Source: Clinical Lung Cancer - May 25, 2021 Category: Cancer & Oncology Authors: Dimana Dimitrova Zohreh Nademi Maria Elena Maccari Stephan Ehl Gulbu Uzel Takahiro Tomoda Tsubasa Okano Kohsuke Imai Benjamin Carpenter Winnie Ip Kanchan Rao Austen J J Worth Alexandra Laberko Anna Mukhina B énédicte Néven Despina Moshous Carsten Speck Source Type: research

Post-transplant food anaphylaxis in an adult cord blood transplant recipient (Ms. No. IJHM-D-20-01037R1)
Int J Hematol. 2021 Mar 27. doi: 10.1007/s12185-021-03140-8. Online ahead of print.ABSTRACTTransplant acquired food allergy (TAFA) is a well-known complication following pediatric liver transplantation, but post-cord blood transplantation (post-CBT) TAFA has rarely been reported. Here, we describe a case of new-onset food anaphylaxis after CBT in an adult patient that demonstrates that post-CBT allergen-challenge is not a risk for long-term allergic sensitization even in adult recipients. The patient was a 39-year-old Japanese man with aggressive NK cell leukemia. He had no previous history of allergies. After receiving CB...
Source: International Journal of Hematology - March 27, 2021 Category: Hematology Authors: Ai Kawahara Tsukasa Nakanishi Midori Goto Kenichi Akao Takefumi Katsuragi Junichi Tsukada Source Type: research

Necrotizing Enterocolitis Following Pediatric Living Donor Liver Transplant
Exp Clin Transplant. 2021 Mar 16. doi: 10.6002/ect.2020.0287. Online ahead of print.ABSTRACTNecrotizing enterocolitis is one of the most common and worrying diseases in neonates, commonly shown in premature neonates, and is associated with significant mortality and morbidity. Necrotizing enterocolitis is characterized by intestinal mucosal injury that can progress to transmural bowel necrosis, and radiologically it can present with either pneumatosis intestinalis or portal venous gas. It is postulated to develop in an immunocompromised host in the setting of bacterial colonization, usually after administration of non-breas...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - March 19, 2021 Category: Transplant Surgery Authors: Krishna Ramavath Sadhna B B Lal Arunanshu Behera Lileswar Kaman Divya Dahiya Cherring Tandup Kaptan Singh Reddy Abhinay Deeban Ganesan Vybhav Venkatesh Source Type: research