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Procedure: Gastroschisis Repair

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Total 540 results found since Jan 2013.

Role of Mesenchymal Stem Cells and Short Chain Fatty Acids in Allergy: A Prophylactic Therapy for Future
Immunol Lett. 2023 Jun 2:S0165-2478(23)00096-2. doi: 10.1016/j.imlet.2023.06.002. Online ahead of print.ABSTRACTAllergic diseases are broadly classified as IgE-mediated type-I hypersensitivity immune reactions due to exposure to typically harmless substances known as allergens. These allergenic substances activate antigen presenting cells, which further triggers T-helper 2 cells immune response and class switch B-cells for synthesis of allergen-specific IgE, followed by classical activation of inflammatory mast cells and eosinophils, which releases preformed mediators involved in the cascade of allergic symptoms. However, ...
Source: Immunology Letters - June 4, 2023 Category: Allergy & Immunology Authors: Mrudula M Mohanan Radhakrishna Shetty Claus Heiner Bang-Berthelsen Kiran Kumar Mudnakudu-Nagaraju Source Type: research

CD4 < sup > + < /sup > T cell memory
Nat Immunol. 2023 May 8. doi: 10.1038/s41590-023-01510-4. Online ahead of print.ABSTRACTSpecialized subpopulations of CD4+ T cells survey major histocompatibility complex class II-peptide complexes to control phagosomal infections, help B cells, regulate tissue homeostasis and repair or perform immune regulation. Memory CD4+ T cells are positioned throughout the body and not only protect the tissues from reinfection and cancer, but also participate in allergy, autoimmunity, graft rejection and chronic inflammation. Here we provide updates on our understanding of the longevity, functional heterogeneity, differentiation, pla...
Source: Cancer Control - May 8, 2023 Category: Cancer & Oncology Authors: Marco K ünzli David Masopust Source Type: research

The optimal operative protocol to accomplish CO2-EVAR resulting from a prospective interventional multicenter study
Objectives: Carbon dioxide (CO2) angiography for endovascular aortic repair (CO2-EVAR) is used to treat abdominal aortic aneurysms (AAAs), especially in patients with chronic kidney disease or allergy to iodinated contrast medium (ICM). However, some technical issues regarding the visualization of the lowest renal artery (LoRA) and the best quality image through angiographies performed from pigtail or introducer sheath are still unsolved. The aim of this study was to analyze different steps of CO2-EVAR to create an operative standardized protocol.
Source: European Journal of Vascular and Endovascular Surgery - May 1, 2023 Category: Surgery Authors: Andrea Vacirca, Gianluca Faggioli, Roberta Vaccarino, Nuno Dias, Martin Austermann, Marco Virgilio Usai, Alexander Oberhuber, Johannes Frederik Sch äfers, Theodosios Bisdas, Nikolaos Patelis, Sergio Palermo, Mauro Gargiulo Source Type: research

Tuft cells - the immunological interface and role in disease regulation
Int Immunopharmacol. 2023 Mar 27;118:110018. doi: 10.1016/j.intimp.2023.110018. Online ahead of print.ABSTRACTTuft cells, also known as taste chemosensory cells, accumulate during parasite colonization or infection and have powerful immunomodulatory effects on substances that could be detrimental, as well as possible anti-inflammatory or antibacterial effects. Tuft cells are the primary source of interleukin (IL)-25. They trigger extra Innate lymphoid type-2 cells (ILC2) in the intestinal lamina propria to create cytokines (type 2); for instance, IL-13, which leads to an increase in IL-25. As tuft cells can produce biologi...
Source: International Immunopharmacology - March 29, 2023 Category: Allergy & Immunology Authors: Safia Iqbal Md Rezaul Karim Deok-Chun Yang Ramya Mathiyalagan Se Chan Kang Source Type: research

Demographic, clinical, immunological, and molecular features of iranian national cohort of patients with defect in DCLRE1C gene
DCLRE1C gene mutation leads to Artemis deficiency, a severe form of combined immunodeficiency (SCID). Impaired DNA repair and block in early adaptive immunity maturation results in T-B-NK+  immunodeficiency associ...
Source: Allergy, Asthma and Clinical Immunology - February 21, 2023 Category: Allergy & Immunology Authors: Soodeh Ghadimi, Mahnaz Jamee, Hassan Abolhassani, Nima Parvaneh, Nima Rezaei, Samaneh Delavari, Mahnaz Sadeghi-Shabestari, Sedigheh Rafiei Tabatabaei, Alireza Fahimzad, Shahnaz Armin, Zahra Chavoshzadeh and Samin Sharafian Tags: Research Source Type: research

Autoimmunity and hernia mesh: fact or fiction?
ConclusionThere is little evidence that the use of polypropylene mesh can lead to autoimmunity. A large number of potential triggers of autoimmunity along with the genetic predisposition to autoimmune disease and the commonality of hernia, make a cause and effect difficult to unravel at present. Biomaterials cause foreign body reactions, but a chronic foreign body reaction does not indicate autoimmunity, a common misunderstanding in the literature.
Source: Hernia - February 4, 2023 Category: Sports Medicine Source Type: research

Malignancy in Ataxia-Telangiectasia (A-T)
A-T is an autosomal recessive DNA repair disorder caused by biallelic mutations in the ATM gene. Clinical features include immunodeficiency, neurodegeneration and cancer predisposition. About 25% of A-T patients will develop early onset malignancies, which are difficult to treat given hypersensitivity to radiation and radiomimetic drugs. Cancer is a leading cause of death in A-T patients.
Source: Journal of Allergy and Clinical Immunology - February 1, 2023 Category: Allergy & Immunology Authors: Aimee Magnarelli, Richa Sharma, Howard Lederman Source Type: research

The Role of a DNA Repair Protein NEIL2 in Regulating Allergic Airway Inflammation
Mammalian Nei-like DNA glycosylase 2 (NEIL2) is a multifunctional protein; it initiates the repair of oxidized DNA bases from the transcriptionally active sequences and also acts as an anti-inflammatory factor. We recently demonstrated that NEIL2 regulates NFkB-mediated gene expression by competing with NFkB for promoter occupancy.  Here we examined the role of NEIL2 in expression of NFkB-regulated genes that are known to contribute to allergic lung inflammation.
Source: Journal of Allergy and Clinical Immunology - February 1, 2023 Category: Allergy & Immunology Authors: Nisha Tapryal, Koa Hosoki, Anirban Chakraborty, Sanjiv Sur Source Type: research

Cancers, Vol. 15, Pages 764: Clinical and Immunologic Characteristics of Non-Hematologic Cancers in Patients with Inborn Errors of Immunity
n Abolhassani Inborn errors of immunity (IEI) are a heterogeneous group of inherited disorders, and almost 500 genes associated with these disorders have been identified. Defects in IEI genes lead to diverse clinical manifestations including increased susceptibility to recurrent or prolonged infections, immune dysregulation phenotypes (such as severe atopy, allergy, autoimmunity, and uncontrolled inflammation, lymphoproliferation), as well as predisposition to malignancies. Although the majority of IEI patients present hematologic cancers, the characteristics of other types of cancers are not well described in these gr...
Source: Cancers - January 26, 2023 Category: Cancer & Oncology Authors: Samaneh Delavari Yating Wang Tannaz Moeini shad Salar Pashangzadeh Farzad Nazari Fereshte Salami Hassan Abolhassani Tags: Article Source Type: research

Chimeric antigen receptor (CAR)-based therapies beyond cancer
This article is protected by copyright. All rights reserved.PMID:36649259 | DOI:10.1002/eji.202250184
Source: European Journal of Immunology - January 17, 2023 Category: Allergy & Immunology Authors: Mar ía Velasco-de Andrés Guillermo Mu ñoz-Sánchez Laura Carrillo-Serradell Mar ía Del Mar Gutiérrez-Hernández Cristina Catal à Marcos Isamat Francisco Lozano Source Type: research

Expression of PD-1 in Tumor Cells is Associated with Shorter Survival in Non-metastatic Intestinal-type Gastric Adenocarcinoma
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):600-615. doi: 10.18502/ijaai.v21i6.11519.ABSTRACTThere is an urgent need to discover novel prognostic biomarkers and treatment strategies for gastric cancer (GC) patients. Several immune-related markers have been proposed as prognostic tools and immunotherapeutic targets to manage diseases. In this regard, we evaluated the expression pattern and prognostic significance of programmed death-1 (PD-1), programmed death-ligand 1 (PD-L1), CD45RO+ tumor-infiltrating lymphocytes (TILs), and DNA mismatch repair (MMR) proteins (MLH1, MSH2, PMS2, and MSH6) in non-metastatic intestinal-...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Niloofar Namvar Mehdi Montazer Simin Ahmadvand Bahare Sadeghian Abbas Ghaderi Source Type: research