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Therapy: Antibiotic Therapy

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Total 169 results found since Jan 2013.

Treatment of Sinusitis Following Dental Implantation: A Systematic Review and Meta-Analysis
CONCLUSIONS: Endoscopic sinus surgery appears to be the most frequent treatment of choice for sinusitis following dental implantation, with excellent success rates. The protean clinical picture drawn from the selected studies calls for the standardization of diagnostics and definitions in this field to enable direct comparisons between the results of different studies. The role of postoperative antibiotic therapies, which have been employed unevenly across studies, should also be prospectively investigated.PMID:35244478 | DOI:10.1177/19458924221084484
Source: American Journal of Rhinology and Allergy - March 4, 2022 Category: ENT & OMF Authors: Fabiana Allevi Gian Luca Fadda Cecilia Rosso Federica Martino Carlotta Pipolo Giovanni Cavallo Giovanni Felisati Alberto Maria Saibene Source Type: research

Impact of Beta-Lactam Allergies on Selection of Antimicrobials in an Inpatient Setting Among Veteran Population.
Authors: Neu DW, Guidry TJ, Gillion AR, Pattanaik DN Abstract PURPOSE: Beta-lactam antibiotics are among the most common and widely used antibiotics. However, reported allergy to this class of antibiotics is also common, leading to the use of alternative broad-spectrum antibiotics by healthcare providers. This has led to the emergence of various negative health outcomes. The purpose of the study is to investigate the impact of using alternative antibiotics secondary to a beta-lactam allergy among U.S. veterans who have otherwise multiple comorbidities. METHODS: This retrospective observational analysis was cond...
Source: Military Medicine - January 23, 2021 Category: International Medicine & Public Health Tags: Mil Med Source Type: research

Extraction Socket Grafting and Ridge Augmentation Failures Associated with Clindamycin Antibiotic Therapy: A Retrospective Study.
CONCLUSION: Penicillin allergy and the use of clindamycin following SG and RA procedures was associated with a higher rate of infection and may be a risk factor for bone augmentation complications. PMID: 33600532 [PubMed - in process]
Source: International Journal of Oral and Maxillofacial Implants - February 20, 2021 Category: ENT & OMF Tags: Int J Oral Maxillofac Implants Source Type: research

Penicillin skin testing as an antimicrobial stewardship initiative.
CONCLUSION: In patients with a self-reported penicillin allergy, PST led to a reduction in the use of carbapenems, aztreonam, vancomycin, and other broad-spectrum agents within a health system. A decrease in drug costs was documented in a sample of patients switched to a penicillin or a cephalosporin after PST. PMID: 28179249 [PubMed - in process]
Source: American Journal of Health-System Pharmacy : AJHP - February 10, 2017 Category: Drugs & Pharmacology Authors: Jones BM, Bland CM Tags: Am J Health Syst Pharm Source Type: research

A Comparison of Three Different Bioinformatics Analyses of the 16S –23S rRNA Encoding Region for Bacterial Identification
Conclusion The higher resolution at the species level identification provided by 16S–23S rRNA encoding region NGS makes its use in routine diagnostic microbiology potentially attractive. Particularly, data analysis is one of the most important steps of a diagnostic workflow, which requires an optimal pipeline for the interpretation of the sequencing data in a short time. This study demonstrates that de novo assembly and subsequent BLASTN analysis using an in-house developed database compared to OTU clustering and mapping approaches is the most accurate and fastest approach for identification of bacterial pathogens....
Source: Frontiers in Microbiology - April 15, 2019 Category: Microbiology Source Type: research

Clinical Practice Guideline (Update): Adult Sinusitis
Objective This update of a 2007 guideline from the American Academy of Otolaryngology—Head and Neck Surgery Foundation provides evidence-based recommendations to manage adult rhinosinusitis, defined as symptomatic inflammation of the paranasal sinuses and nasal cavity. Changes from the prior guideline include a consumer added to the update group, evidence from 42 new systematic reviews, enhanced information on patient education and counseling, a new algorithm to clarify action statement relationships, expanded opportunities for watchful waiting (without antibiotic therapy) as initial therapy of acute bacterial rhinos...
Source: Otolaryngology - Head and Neck Surgery - April 1, 2015 Category: ENT & OMF Authors: Rosenfeld, R. M., Piccirillo, J. F., Chandrasekhar, S. S., Brook, I., Ashok Kumar, K., Kramper, M., Orlandi, R. R., Palmer, J. N., Patel, Z. M., Peters, A., Walsh, S. A., Corrigan, M. D. Tags: Guideline Source Type: research

Contribution of Non-immune Cells to Activation and Modulation of the Intestinal Inflammation
Conclusions As the intestinal mucosa surface constitutes the major surface of the body which is in direct contact with the outer environment, intestinal immune homeostasis must be accurately regulated. The interplay between commensal microbiota, intestinal stromal cells, and the mucosal immune system components should guarantee the intestinal homeostasis to avoid a sustained inflammation that could induce tissue damage. However, several factors can lead to inflammation through homeostasis breakdown. Figure 1 summarizes the main points that have been reviewed here. We have described what it is known so far about the role o...
Source: Frontiers in Immunology - April 9, 2019 Category: Allergy & Immunology Source Type: research

Pharmacist-driven penicillin skin testing service for adults prescribed nonpreferred antibiotics in a community hospital.
CONCLUSION: A pharmacist-driven PST service was successfully implemented in a community hospital setting. PMID: 31677260 [PubMed - as supplied by publisher]
Source: American Journal of Health-System Pharmacy : AJHP - October 30, 2019 Category: Drugs & Pharmacology Authors: Englert E, Weeks A Tags: Am J Health Syst Pharm Source Type: research

Why should antibiotic therapy be avoided in case of acute infectious diarrhea?.
Abstract Antibiotic prescription for acute diarrhea is not devoid of risks. There are individual risks for the patient, such as allergy, gastrointestinal side effects, Clostridium difficile infection. There is also a risk of selection of antibiotic resistance in the digestive microbiota, leading to the emergence of multiresistant isolates such as extended-spectrum β-lactamase or carbapenemase producing Enterobacteriaceae, which are able to disseminate worldwide. Antibiotic prescriptions may thus be limited to patients with entero-invasive or severe choleriform diarrhea. PMID: 23228474 [PubMed - in process]
Source: Presse Medicale - January 1, 2013 Category: Journals (General) Authors: Lefort A Tags: Presse Med Source Type: research

Antibiotics may not improve short-term or long-term outcomes in acute uncomplicated diverticulitis
This study evaluates whether or not antibiotic therapy for acute uncomplicated left-sided diverticulitis improves recovery. Methods A non-blinded randomised clinical trial comparing treatment of acute uncomplicated left-sided diverticulitis with or without antibiotics was performed. Adult patients were enrolled if they had a history and clinical signs of acute diverticulitis, a raised white cell count (WCC) and...
Source: Evidence-Based Medicine - January 17, 2013 Category: Internal Medicine Authors: Westwood, D. A., Eglinton, T. W. Tags: Inflammatory bowel disease, Clinical trials (epidemiology), Immunology (including allergy), Pain (neurology), Chemotherapy, Radiology, Clinical diagnostic tests, Radiology (diagnostics) Therapeutics Source Type: research

Patterns of Care Before and After the Adult Sinusitis Clinical Practice Guideline
ConclusionsCare patterns for the medical treatment of acute adult sinusitis have changed after guideline publication, with an increase in oral antibiotic prescription rates in cases of acute sinusitis and increase in the use of amoxicillin as the first‐line antimicrobial agent. The latter is strongly in keeping with guideline recommendation. Clinicians' espousal of the analgesic recommendations likely needs improvement to better comply with guideline recommendations. Level of Evidence2b. Laryngoscope, 2013
Source: The Laryngoscope - February 16, 2013 Category: ENT & OMF Authors: Neil Bhattacharyya, Lynn J. Kepnes Tags: Allergy/Rhinology Source Type: research

Audit on the diagnosis and management of childhood Urinary Tract Infections (UTIs)
Conclusions Overall the standards were well adhered to, more so in the diagnostic process than with treatment. Variance in clinical judgement and practice plays a large role in the diagnosis of childhood UTIs and as such, may account for non-adherence to guidelines when requesting tests. Adherence to treatment guidelines is poor according to these results. It was not possible to ascertain reasons for deviation from protocol from the records. Clinical judgement over oral versus IV treatment may depend on other factors not measured by this audit. Adherence to antibiotic guidelines in this audit was extremely poor, highlighti...
Source: Archives of Disease in Childhood - May 9, 2013 Category: Pediatrics Authors: Ford, N., Benn, C. Tags: Oncology, Urology, Immunology (including allergy), Drugs: infectious diseases, Urinary tract infections, Child health, Renal medicine, Clinical diagnostic tests, Urinary tract infections, Guidelines Abstracts from the Poster and Oral presentations from Source Type: research

Aztreonam for febrile neutropenia in patients with beta‐lactam allergy
ConclusionAztreonam monotherapy may be acceptable for use in patients with a history of beta‐lactam hypersensitivity or following an adverse reaction with another beta‐lactam. Further studies are needed to compare efficacy of aztreonam monotherapy with other therapies for the treatment of FN.
Source: Transplant Infectious Disease - October 14, 2013 Category: Transplant Surgery Authors: B.J. McCullough, L.E. Wiggins, A. Richards, K. Klinker, J.W. Hiemenz, J.R. Wingard Tags: Short Communication Source Type: research

Central skull base osteomyelitis
ConclusionsOsteomyelitis of the central skull base poses significant challenges for timely and accurate diagnosis. Aggressive management with antimicrobials, coupled with surgical debridement in select cases, may avoid serious neurologic morbidity and mortality. Level of EvidenceNA Laryngoscope, 2013
Source: The Laryngoscope - November 7, 2013 Category: ENT & OMF Authors: Andrew K. Johnson, Pete S. Batra Tags: Allergy/Rhinology Source Type: research