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Introduction.
Authors: Giulini SM, Stagnitti F
Abstract
There is no doubt that postgraduate education and all "professional development activity" is in crisis, not only in our country but in all of Europe. The crisis is on one hand due to a lack of resources which has been evident for more than a decade, and on the other hand due to factors such as organization, culture, and education. Many of the chief medical disciplines such as internal medicine or general surgery, have been literally crushed and replaced by a myriad of subspecialties that have undermined the original unified character of the main disciplines 1. The teaching ...
Source: Annali Italiani di Chirurgia - December 11, 2019 Category: Surgery Tags: Ann Ital Chir Source Type: research
Owlstone Medical raises $15m to commercialize breath biopsy platform
Owlstone Medical touted today that it raised $15 million to support the commercialization of its breathalyzer diagnostic device.
Funds from the round, co-led by Horizons Ventures and Aviva Ventures, will also be used to expand the company’s pipeline and the precision medicine services that it provides to the pharma industry, according to the Cambridge, England-based company.
Owlstone Medical’s breath biopsy platform is designed to measure volatile organic compounds in a person’s breath as a means to diagnose particular diseases.
The company has collaborated with Cancer Research U.K. to launch a study eval...
Source: Mass Device - March 5, 2018 Category: Medical Devices Authors: Sarah Faulkner Tags: Diagnostics Funding Roundup Oncology Owlstone Medical Source Type: news
Wright Medical slides after pricing offering to back Cartiva buyout
Wright Medical (NSDQ:WMGI) shares traded down this morning after it priced an offering it plans to use to fund the $435 million buyout of Cartiva.
Wright said it plans to finance the Cartiva purchase, announced yesterday morning, with an equity offering. Alpharetta, Ga.-based Cartiva makes a synthetic cartilage implant for treating arthritis in the big toe.
Yesterday afternoon Wright said it plans to float nearly 18.3 million shares at $24.60 apiece, for expected net proceeds of $423 million. Underwritten by J.P. Morgan, the offering is slated to close August 30, Memphis-based Wright said.
WMGI shares closed down -4.2%...
Source: Mass Device - August 28, 2018 Category: Medical Devices Authors: Brad Perriello Tags: Funding Roundup Mergers & Acquisitions Orthopedics Wall Street Beat Cartiva Extremities wrightmedical Source Type: news
Cochrane Lifetime and Emeritus Members
Cochrane is proud to announce new lifetime and emeritus memberships,recognizing the extraordinary contributions of individuals who have made an exceptional, long-standing contribution to Cochrane ’s work and leadership.Cochrane ' s strength is in its collaborative, global community. Over the last 30 years, our members and supporters from more than 130 countries have worked together to produce credible, accessible health information and help inform health decision-making. Though we are spread out across the globe, our shared passion for health evidence unites us.Cochrane ’s Membership schemehelps reward everyone who hel...
Source: Cochrane News and Events - May 3, 2023 Category: Information Technology Authors: Muriah Umoquit Source Type: news
Lipidomic Analysis Reveals Serum Alteration of Plasmalogens in Patients Infected With ZIKA Virus
Discussion
Our strategy in this study was to compare the serum lipid profile between ZIKV patients and symptomatic controls that presented virus-like symptoms as fever, arthralgia, headache, exanthema, myalgia and pruritus. Retro-orbital pain and fever were the only clinical symptoms that significantly distinguished ZIKV and control groups (Table 1). A recent study by Melo et al. (2017) showed that the differences in metabolic and lipid profiles in serum of ZIKV patients are so pronounced that they can be differentiated from a control group composed of both healthy and symptomatic subjects. Thus, by using symptomatic pati...
Source: Frontiers in Microbiology - April 11, 2019 Category: Microbiology Source Type: research
Living at the Extremes: Extremophiles and the Limits of Life in a Planetary Context
Nancy Merino1,2,3, Heidi S. Aronson4, Diana P. Bojanova1, Jayme Feyhl-Buska1, Michael L. Wong5,6, Shu Zhang7 and Donato Giovannelli2,8,9,10*
1Department of Earth Sciences, University of Southern California, Los Angeles, CA, United States
2Earth-Life Science Institute, Tokyo Institute of Technology, Tokyo, Japan
3Biosciences and Biotechnology Division, Physical and Life Sciences Directorate, Lawrence Livermore National Lab, Livermore, CA, United States
4Department of Biology, University of Southern California, Los Angeles, CA, United States
5Department of Astronomy – Astrobiology Program, University of Was...
Source: Frontiers in Microbiology - April 14, 2019 Category: Microbiology Source Type: research
Surveillance and Genomics of Toxigenic Vibrio cholerae O1 From Fish, Phytoplankton and Water in Lake Victoria, Tanzania
This study reports the occurrence of multidrug resistant V. cholerae O1 in Lake Victoria that are genetically closely related to recent pandemic strains in Tanzania, Kenya and Uganda. The strains identified are also closely related to older pandemic strains recovered in the Democratic Republic of Congo, Burundi and Tanzania up until 1993, suggesting a long-term persistence and wide spatial distribution of pandemic strains within the region with the lake serving as a reservoir. These environmental isolates likely emerged from previous cholera outbreaks and survived in the lake environment for decades through various relatio...
Source: Frontiers in Microbiology - April 29, 2019 Category: Microbiology Source Type: research
The Bible, Donald Trump and Plastic
Credit: u/USMCinUSABy Jan LundiusSTOCKHOLM / ROME, Jun 5 2020 (IPS) Another episode of the spectacular show that could be called The Greatest Story Ever Told: The Saga of the Trump Presidency, scripted and acted by Trump himself, took place on 1st of June.
As U.S. cities were scenes of demonstrations and looting, President Trump declared himself to be ”the president of law and order” and said he was going to dispatch ”thousands and thousands” of law enforcement personell to Washington, to stop the ”destruction of property”. Meanwhile, tear gas, rubber bullets, shields and horses were used to empty the Lafayett...
Source: IPS Inter Press Service - Health - June 5, 2020 Category: International Medicine & Public Health Authors: Jan Lundius Tags: Crime & Justice Environment Featured Global Headlines Health Human Rights North America Religion TerraViva United Nations Water & Sanitation Source Type: news
Regulator of Angiogenesis and Vascular Function: A 2019 Update of the Vasoinhibin Nomenclature
Jakob Triebel1*, Juan Pablo Robles2, Magdalena Zamora2, Gonzalo Martínez de la Escalera2, Thomas Bertsch1 and Carmen Clapp2
1Institute for Clinical Chemistry, Laboratory Medicine and Transfusion Medicine, General Hospital Nuremberg and Paracelsus Medical University Nuremberg, Nuremberg, Germany
2Instituto de Neurobiología, Universidad Nacional Autónoma de México, Querétaro, Mexico
Proteolytic cleavage of prolactin (PRL), the human anterior pituitary hormone fundamental for lactation can generate vasoinhibin, a peptide-hormone with endocrine, paracrine, and autocrine ef...
Source: Frontiers in Endocrinology - April 9, 2019 Category: Endocrinology Source Type: research
Age of despair or age of hope? Elderly Palestinian women's perspectives on health in midlife
Publication date: 21 February 2018 Source:The Lancet, Volume 391, Supplement 1 Author(s): Doaa Hammoudeh, Ernestina Coast, Rita Giacaman, David Lewis, Yoke Rabaia, Tiziana Leone Background Few studies exist of women's experiences and understanding of health in the transition from reproductive to post-reproductive age. Available data is from high-income settings, and most studies tend to focus on women of reproductive age. Little is known about women's perspectives in the Palestinian context. The aim of this study was to add to our understanding of Palestinian women's midlife experiences, looking beyond reproduction and ch...
Source: The Lancet - February 23, 2018 Category: General Medicine Source Type: research
Selection of New Probiotics for Endometrial Health
In this study, vaginal microbiome was divided in five biotypes, being four of them dominated by lactobacilli and considered as healthy (pH < 5.0) and defining the group IV with higher pH (pH > 5.0) and higher diversity. In a healthy status, microbiota is balanced and forms a stable ecological unit dominated by Lactobacillus species, which fixes pH below 5.0 and controls non-desirable groups. In a pathogenic process, the microbiome shifts to a dysbiotic state, in which lactobacilli drop, pH is increased to values above 4.5 and other groups such as Gardnerella, Atopobium, Prevotella, and Streptococcus, among ...
Source: Frontiers in cellular and infection microbiology - April 16, 2019 Category: Microbiology Source Type: research
Protective Effect of Resveratrol on Benzo(a)Pyrene Induced Dysfunctions of Steroidogenesis and Steroidogenic Acute Regulatory Gene Expression in Leydig Cells
In this study the molecular mechanism of B(a)P induced Leydig cell steroidogenic dysfunctions and its protective mechanism of action with a natural Aryl hydrocarbon receptor (AhR) antagonist and anti-oxidant, Resveratrol (Res) has been investigated. B(a)P exposure induced ROS mediated steroidogenic imbalance via activation of p38MAPK and repression of testosterone level as well as other steroidogenic enzymes like CYPIIA1, 3β-HSD, 17β-HSD expressions. B(a)P exposure decreased StAR protein expression along with increased DAX-1, a transcriptional repressor of StAR gene. Along with that B(a)P decreased the expr...
Source: Frontiers in Endocrinology - April 29, 2019 Category: Endocrinology Source Type: research
Microbial Diversity and Antimicrobial Resistance Profile in Microbiota From Soils of Conventional and Organic Farming Systems
According to this study it may be outlined that soil microbiota is a stable component as it were detected similar composition of microorganisms in soil both in organic as well as in conventional farming systems with similar soil structure and pH. The different amount of phosphorus in soils had no influence on bacterial variety at a genera level although more investigations would be useful to investigate changes among separate species. During evolution microorganisms adapted to survive in ecosystems independently of certain changes and probably serve as a buffer for ecological niches. It is unclear, however, what level of i...
Source: Frontiers in Microbiology - April 25, 2019 Category: Microbiology Source Type: research
“It’s Worrisome to Not Have Data.” An Expert Questions Whether Air Is Safe After Train Derailment
Questions of air safety remain in East Palestine, Ohio, following the Feb. 3 train derailment that sent industrial chemicals, including the carcinogen vinyl chloride, into the atmosphere. Ohio Governor Mike DeWine cleared residents who had evacuated to return home this week, stating that repeated air testing conducted by the U.S. Environmental Protection Agency (EPA) was no longer revealing dangerous levels of any contaminants.
But the agency has yet to publicly release any quantifiable data on the area’s pollution. The result is confusion about exactly what may or may not be lingering in the air, and what that mean...
Source: TIME: Health - February 17, 2023 Category: Consumer Health News Authors: Haley Weiss Tags: Uncategorized healthscienceclimate News Public Health Source Type: news
These Women Are Transforming What Climate Leadership Looks Like. Here ’s What They Learned From the Pandemic
The COVID-19 pandemic, like the climate crisis, is amplifying existing racial and gender injustices in our society. TIME editors Naina Bajekal and Elijah Wolfson moderated a conversation with two women working to create a more inclusive climate leadership space: American author, strategist and teacher Katharine Wilkinson, who co-founded and leads The All We Can Save Project to nurture a leaderful climate community; and queer Colombian activist Maria Alejandra Escalante, who is the climate and environmental justice advocacy officer at FRIDA The Young Feminist Fund, which supports young feminist organizers in the Global Sout...
Source: TIME: Science - April 20, 2021 Category: Science Authors: Naina Bajekal and Elijah Wolfson Tags: Uncategorized climate change Londontime Magazine TIME 2030 Source Type: news
