Surveillance and Genomics of Toxigenic Vibrio cholerae O1 From Fish, Phytoplankton and Water in Lake Victoria, Tanzania

This study reports the occurrence of multidrug resistant V. cholerae O1 in Lake Victoria that are genetically closely related to recent pandemic strains in Tanzania, Kenya and Uganda. The strains identified are also closely related to older pandemic strains recovered in the Democratic Republic of Congo, Burundi and Tanzania up until 1993, suggesting a long-term persistence and wide spatial distribution of pandemic strains within the region with the lake serving as a reservoir. These environmental isolates likely emerged from previous cholera outbreaks and survived in the lake environment for decades through various relations with reservoirs such as phytoplankton and fish. The V. cholerae O1 strains in the lake are potential progenitors of future cholera outbreak strains. Our findings are important for surveillance of V. cholerae O1 and understanding the epidemiology of cholera in countries around the lake. Ethics Statement The present study required no ethical approval since the analyzed samples were collected from the environment, namely water, phytoplankton and carp from Lake Victoria. We, however, obtained a research permit from local authorities in Mwanza, the study area for collection of these samples in the Mwanza basin of Lake Victoria. The permit issued in Kiswahili Language is submitted with the Manuscript only for editorial use. Author Contributions YH collected samples and carried out the study in the laboratory, analyzed the results, and drafted the manuscript...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research

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Abstract The dehydration reaction of tetraamino porphyrin and 4,4'-biphenyldicarboxaldehyde was performed for the synthesis of a novel covalent organic framework (COF), which was decorated on magnetic Fe3O4 to obtain core-shell structured Fe3O4@COFs nanospheres for the first time, for effective extraction and enrichment of sulfonamides (SAs). The morphology and structure of the synthesized nanospheres were characterized through various methods. The extraction conditions for six SAs including sulfadiazine, sulfamerazine, sulfamethazine, sulfamonomethoxine, sulfamethoxazole, sulfadimethoxine were systematically opti...
Source: Analytica Chimica Acta - Category: Chemistry Authors: Tags: Anal Chim Acta Source Type: research
Abstract It is of great importance to detect chlorotetracycline (CTC) in a highly sensitive and specific way because of its wide distribution in aquaculture and animal husbandry. Herein, we propose a novel ratiometric fluorescence strategy to assay CTC by using bovine serum albumin stabilized gold nanoclusters (BSA-AuNCs). The BSA-AuNCs consisting of 25 gold atoms (Au25NCs) display a red emission at 640 nm (λex = 370 nm). In the presence of CTC, a new blue emission at 425 nm is emerged and its intensity dramatically increases with the addition of more the analyte; meanwhile the red emission at 640...
Source: Analytica Chimica Acta - Category: Chemistry Authors: Tags: Anal Chim Acta Source Type: research
New J. Chem., 2019, Accepted Manuscript DOI: 10.1039/C9NJ04275J, PaperYingchun Gao, Yingguo Zhao, Xiao-Wei Song, Rong-Yi Huang, Yan Meng, Junwei Wang, Wenjing Wang, Chengneng Chen A copper complex based on the pentadentate aminopyridine ligand [(9-methyl-1,10-phenanthrolin-2-yl)methyl]bis-(pyridin-2-ylmethyl)amine (Dmphen-DPA), namely, [Cu(Dmphen-DPA)](ClO4)2 (1), was synthesized and characterized by elemental analysis, HR-MS spectra and X-ray single crystal diffraction. The complex... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - New J. Chem. latest articles - Category: Chemistry Authors: Source Type: research
J. Mater. Chem. A, 2019, Accepted Manuscript DOI: 10.1039/C9TA10002D, CommunicationRong Wang, Boxin Wang, Jianqiu Wang, Xuning Zhang, Dongyang Zhang, Donghui Wei, Xiaobo Sun, Huiqiong Zhou, Yuan Zhang Although the boost of power conversion efficiency (PCE) in organic photovoltaic cells (OSC) has been benefited from the development of novel donors and non-fullerene acceptors, state-of-the art devices commonly utilize... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - J. Mater. Chem. latest articles - Category: Chemistry Authors: Source Type: research
Dalton Trans., 2019, Accepted Manuscript DOI: 10.1039/C9DT03990B, PaperMathew David Anker, Yasir Altaf, Matthias Lein, Martyn P Coles The indyl anion, K[In(NONDipp)] (NONDipp = [O(SiMe2NDipp)2]2 –, Dipp = 2,6-iPr2C6H3) reacts with group 12 compounds M(BDIR)Cl (M = Zn, Cd; BDI = [HC{C(Me)NR}2]–, R = 2,4,6-Me3C6H2 (Mes), Dipp) to afford... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Dalton Trans. latest articles - Category: Chemistry Authors: Source Type: research
Analyst, 2019, Accepted Manuscript DOI: 10.1039/C9AN01513B, PaperMayank ., Richa Rani, Ashutosh Singh, Neha Garg, Navneet Kaur, Narinder Singh Labelling and imaging of mitochondria and nucleolus have attracted very great attention because of the involvement of these cellular organelles in critical cellular activities. Therefore, a large number of mitochondria... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Analyst latest articles - Category: Chemistry Authors: Source Type: research
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Source: Quality of Life Research - Category: Health Management Source Type: research
ConclusionsSelf-rated health of the general US adult population in 2017 was similar to 2002, but after adjusting for health problems, scores were slightly higher in 2017.  Sociodemographic shifts in age and education explain some of the differences in scores, and by removing health and sociodemographic factors, we found the VAS reveals self-rated health is slightly better in 2017 than 2002.
Source: Quality of Life Research - Category: Health Management Source Type: research
ConclusionsOverall health status is found to be poor among women during the perinatal period compared with the postpartum period. The study indicates that interventions to address the influencing factors are needed to ensure better quality of life for women both pre- and post-birth. Community-based initiatives, such as awareness building, might address negative factors and subsequently improve health status and reduce adverse health outcomes related to pregnancy and postnatal care.
Source: Quality of Life Research - Category: Health Management Source Type: research
The objective of this study was to examine whether sexual satisfaction is associated with subjective well-being longitudinally.MethodsData from 2002, 2008 and 2011 were drawn from a nationally representative study among individuals residing in private households aged 40 and over (n = 12,105 in regression analysis). The established Satisfaction with Life Scale was used to assess life satisfaction. The well-recognized Positive and Negative Affect Schedule was used to quantify positive and negative affect, respectively. A single-item measure was used to quantify sexual satis faction, ranging from 1 to 5 (higher ...
Source: Quality of Life Research - Category: Health Management Source Type: research
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