Selection of New Probiotics for Endometrial Health

In this study, vaginal microbiome was divided in five biotypes, being four of them dominated by lactobacilli and considered as healthy (pH 5.0) and higher diversity. In a healthy status, microbiota is balanced and forms a stable ecological unit dominated by Lactobacillus species, which fixes pH below 5.0 and controls non-desirable groups. In a pathogenic process, the microbiome shifts to a dysbiotic state, in which lactobacilli drop, pH is increased to values above 4.5 and other groups such as Gardnerella, Atopobium, Prevotella, and Streptococcus, among others, can overgrow (Srinivasan et al., 2012). Short chain fatty acids (SCFAs) are a product of anaerobe growth, which include acetate and propionate, together with a depletion of lactic acid due to lower lactobacilli cell counts (Yeoman et al., 2013). Along with their ability to lower the pH, Lactobacillus strains have other potential characteristics that can exert control over unbalanced microorganisms such as the production of hydrogen peroxide (Sgibnev and Kremleva, 2015), bacteriocins (Ocaña et al., 1999b; Aroutcheva et al., 2001), and their capacity of adhesion (Coudeyras et al., 2008). Several studies have demonstrated there is bacterial colonization beyond the vagina, showing that the upper reproductive tract is not sterile (Baker et al., 2018). Recently, a study surveying the female reproductive tract confirmed the existence of a microbiota continuum starting in the vagina and progressing to the deepest organ...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research

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Publication date: 2019Source: Methods in Microbiology, Volume 46Author(s): Surendra Gulla, Dakshayani Lomada, Vadali V.S.S. Srikanth, Muthukonda Venkatakrishnan Shankar, Kakarla Raghava Reddy, Sarvesh Soni, Madhava C. ReddyAbstractNanoparticles' based cancer therapeutics are greatly dependent on the development of science and engineering of nanoparticles. In this article, important strategies based on nanoparticles used for cancer treatment are discussed. The inspiration to write this article is not only to review the existing strategies based on nanoparticles but also to highlight the pertinent and possible solutions ther...
Source: Methods in Microbiology - Category: Microbiology Source Type: research
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Source: Methods in Microbiology - Category: Microbiology Source Type: research
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Source: Methods in Microbiology - Category: Microbiology Source Type: research
Publication date: 2019Source: Methods in Microbiology, Volume 46Author(s): Hemraj ChhipaAbstractExcess use of chemical fertilizers and pesticides has shown negative impacts on soil health and environment. Chemical residues destroy the soil ecosystem by affecting the non-targeted organisms and decrease soil fertility simultaneously. To prevent such adversity in soil and environment, researchers have applied nanotechnology in agriculture. Nanotechnology is the rising technology of the current decade, which has shown promising results in controlling excess agri-inputs and maintaining environmental balance. The characteristics...
Source: Methods in Microbiology - Category: Microbiology Source Type: research
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Source: Methods in Microbiology - Category: Microbiology Source Type: research
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Source: Methods in Microbiology - Category: Microbiology Source Type: research
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Source: Radiation Physics and Chemistry - Category: Physics Source Type: research
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Source: Biocatalysis and Agricultural Biotechnology - Category: Biotechnology Source Type: research
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Source: Biocatalysis and Agricultural Biotechnology - Category: Biotechnology Source Type: research
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