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Total 160 results found since Jan 2013.

The Direct Impact of the COVID ‐19 Pandemic on Rhinology Practice
ConclusionsCOVID-19 significantly affected the number of patients seen, virtual visit encounters, nasal endoscopies, and imaging utilization. Further research is needed to determine if patient outcomes were impacted and if these changes in practice will persist.This article is protected by copyright. All rights reserved
Source: International Forum of Allergy and Rhinology - July 22, 2023 Category: Allergy & Immunology Authors: Sarah R. Sutton, April Taniguchi, Shaun A. Nguyen, Zachary M. Soler, Rodney J. Schlosser Tags: CLINICAL LETTER Source Type: research

Science ’s 2022 Breakthrough of the Year: A telescope’s golden eye sees the universe anew
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Source: ScienceNOW - December 15, 2022 Category: Science Source Type: news

Ctla4 variant of uncertain significance in a patient with a history of cytopenias
CTLA-4 haploinsufficiency is caused by heterozygous mutations in CTLA4, a negative regulator of immune responses. Hypogammaglobulinemia, infections, and autoimmune cytopenias can be seen. Here, we describe a patient with history of ITP who presented with neutropenic fever, lymphopenia, and hypogammaglobulinemia in the setting of COVID-19 with a VUS in CTLA4.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2022 Category: Allergy & Immunology Authors: N. Scanlon, L. Broderick, M. Revier, S. Wang, B. Zuraw, T. Smith Tags: M275 Source Type: research

Active Symptom-Based Surveillance of Adverse Events Following Immunization among Individuals Vaccinated with ChAdOx1 nCoV-19 Coronavirus Vaccine in a Tertiary Hospital of Kerala
CONCLUSION: All the adverse reactions were of a minor type and non-serious. Side effects were less common in older adults (>60 years). Reactions to the second dose were lesser in intensity and frequency. Younger age, history of allergy, and comorbidities, particularly asthma were found to be major predictors for the development of adverse events and require more watchful vaccine administration.PMID:35135453 | DOI:10.2174/1574886317666220207120649
Source: Current Drug Safety - February 9, 2022 Category: Drugs & Pharmacology Authors: Maria Jose Priyanka Rajmohan Joe Thomas Swathi Krishna Beena Antony Unnikrishnan U G Elsy M I Raphael M P Ponnu Jose Lucy Raphael Praveenlal Kuttichira Source Type: research

Advanced Imaging Supports the Mechanistic Role of Autoimmunity and Plaque Rupture in COVID-19 Heart Involvement
AbstractThe cardiovascular system is frequently affected by coronavirus disease-19 (COVID-19), particularly in hospitalized cases, and these manifestations are associated with a worse prognosis. Most commonly, heart involvement is represented by myocarditis, myocardial infarction, and pulmonary embolism, while arrhythmias, heart valve damage, and pericarditis are less frequent. While the clinical suspicion is necessary for a prompt disease recognition, imaging allows the early detection of cardiovascular complications in patients with COVID-19. The combination of cardiothoracic approaches has been proposed for advanced ima...
Source: Clinical Reviews in Allergy and Immunology - January 28, 2022 Category: Allergy & Immunology Source Type: research

Co-Expression and Localization of Angiotensin-Converting Enzyme-2 (ACE2) and the Transmembrane Serine Protease 2 (TMPRSS2) in Paranasal Ciliated Epithelium of Patients with Chronic Rhinosinusitis
CONCLUSION: ECRS patients with type 2 inflammation showed decreased ACE2 and TMPRSS2 expressions in their sinus mucosa. ACE2 and TMPRSS2 regulation seems to be positively related to IFN-γ and TNF-α production in CRS patients; ACE2 and TMPRSS2 were co-expressed in the ciliated epithelium of their paranasal mucosa, implicating the paranasal epithelium as a portal for initial infection and transmission.PMID:34989246 | DOI:10.1177/19458924211059639
Source: American Journal of Rhinology and Allergy - January 6, 2022 Category: ENT & OMF Authors: Tomohiro Kawasumi Sachio Takeno Takashi Ishino Tsutomu Ueda Takao Hamamoto Kota Takemoto Yuichiro Horibe Oda Takashi Source Type: research

Is asthma a risk factor for severe outcomes in COVID 19?
Conclusion: Our study shows that the prevalence of asthma among covid-19 patients is similar to the prevalence in the general population, asthmatic patients are not more prone than others to catching the virus and asthma is not a risk factor for severe outcomes.
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Saidani, A., Maddeh, S., Kallel, N., Moussa, N., Gargouri, R., Kotti, A., Bahloul, N., Fki, W., Kammoun, S. Tags: Allergy and immunology Source Type: research

Investigating the association between allergic diseases and COVID-19 in 400 Iranian patients
CONCLUSION: The results of this study established that allergic diseases were not determined to be a predisposing factor for the severe acute respiratory syndrome (SARS) due to coronavirus 2 (SARS-CoV-2) infection. Significantly, AR patients developed mild clinical manifestations of COVID-19 and admitted to ICU as compared to non-AR patients.PMID:34476916 | DOI:10.15586/aei.v49i5.105
Source: Allergologia et Immunopathologia - September 3, 2021 Category: Allergy & Immunology Authors: Amirhossein Darabi Mohammadrezad Dehghanfard Sara Jozan Rahim Tahmasebi Ali Movahed Marjan Zamani Shokrollah Farrokhi Source Type: research