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Assuring the Groundwork for Success: Mentorship, Sponsorship, and Allyship for Practicing Anesthesiologists
Anesth Analg. 2023 Oct 1;137(4):754-762. doi: 10.1213/ANE.0000000000006646. Epub 2023 Sep 5.ABSTRACTThe challenges facing the health care industry in the post-coronavirus disease 2019 (COVID-19) pandemic world are numerous, jeopardizing wellness, and performance. Maintaining engagement and fulfillment of anesthesiologists in their work is now a critical issue in various practice settings: academic, private practice, and corporate medicine. In this article, we offer insights on how mentorship, sponsorship, and allyship are important in the advancement of the anesthesiology workforce including women and underrepresented mino...
Source: Anesthesia and Analgesia - September 15, 2023 Category: Anesthesiology Authors: Mofya S Diallo Crystal C Wright Alice A Tolbert Coombs Thomas R Vetter Source Type: research

The efficacy of Facebook's vaccine misinformation policies and architecture during the COVID-19 pandemic
Sci Adv. 2023 Sep 15;9(37):eadh2132. doi: 10.1126/sciadv.adh2132. Epub 2023 Sep 15.ABSTRACTOnline misinformation promotes distrust in science, undermines public health, and may drive civil unrest. During the coronavirus disease 2019 pandemic, Facebook-the world's largest social media company-began to remove vaccine misinformation as a matter of policy. We evaluated the efficacy of these policies using a comparative interrupted time-series design. We found that Facebook removed some antivaccine content, but we did not observe decreases in overall engagement with antivaccine content. Provaccine content was also removed, and ...
Source: Adv Data - September 15, 2023 Category: Epidemiology Authors: David A Broniatowski Joseph R Simons Jiayan Gu Amelia M Jamison Lorien C Abroms Source Type: research

Assuring the Groundwork for Success: Mentorship, Sponsorship, and Allyship for Practicing Anesthesiologists
Anesth Analg. 2023 Oct 1;137(4):754-762. doi: 10.1213/ANE.0000000000006646. Epub 2023 Sep 5.ABSTRACTThe challenges facing the health care industry in the post-coronavirus disease 2019 (COVID-19) pandemic world are numerous, jeopardizing wellness, and performance. Maintaining engagement and fulfillment of anesthesiologists in their work is now a critical issue in various practice settings: academic, private practice, and corporate medicine. In this article, we offer insights on how mentorship, sponsorship, and allyship are important in the advancement of the anesthesiology workforce including women and underrepresented mino...
Source: Anesthesia and Analgesia - September 15, 2023 Category: Anesthesiology Authors: Mofya S Diallo Crystal C Wright Alice A Tolbert Coombs Thomas R Vetter Source Type: research

Achieving COVID-19 zero without lockdown, January 2020 to March 2022: The Taiwan model explained
J Formos Med Assoc. 2023 Sep 13:S0929-6646(23)00345-5. doi: 10.1016/j.jfma.2023.09.001. Online ahead of print.ABSTRACTDespite never imposing a lockdown, Taiwan achieved COVID-19 zero, with reporting only 56 local coronavirus disease 2019 (COVID-19) cases after testing 126,987 individuals in 2020, and further contained a large outbreak rapidly and successfully in 2021. At the onset of the COVID-19 pandemic, our infectious disease modeling results indicated that testing and contact tracing alone would fail to contain the pandemic. However, by supplementing this approach with general public surgical mask-wearing, the reproduc...
Source: J Formos Med Assoc - September 15, 2023 Category: General Medicine Authors: Yi-Hsuan Chen Chi-Tai Fang Source Type: research

RNA nanotechnology: A new chapter in targeted therapy
Colloids Surf B Biointerfaces. 2023 Sep 6;230:113533. doi: 10.1016/j.colsurfb.2023.113533. Online ahead of print.ABSTRACTNanoparticles have been widely studied in the fields of biotechnology, pharmacy, optics and medicine and have broad application prospects. Numerous studies have shown significant interest in utilizing nanoparticles for chemically coating or coupling drugs, aiming to address the challenges of drug delivery, including degradability and uncertainty. Furthermore, the utilization of lipid nanoparticles loaded with novel coronavirus antigen mRNA to control the COVID-19 pandemic has led to a notable surge in re...
Source: Colloids and Surfaces - September 15, 2023 Category: Biotechnology Authors: Tongtong Lv Yingying Meng Yifan Liu Yukun Han Hongwu Xin Xiaochun Peng Jinbai Huang Source Type: research

Adjuvant activities of immunostimulating natural products: Astragalus membranaceus (Fisch.) Bge and Coriolus versicolor in BNT162b2 vaccination against COVID-19 infection
In conclusion, combining AM and CV was effective in acting as an oral adjuvant with the mRNA vaccine BNT162b2 to improve the antigen binding activities against SARS-CoV-2 ancestral and variant SARS-CoV-2 spike proteins, probably via trained immunity of macrophages and dendritic cells.PMID:37713617 | DOI:10.1093/jleuko/qiad106
Source: Journal of Leukocyte Biology - September 15, 2023 Category: Hematology Authors: Ben Chung-Lap Chan Peiting Li Miranda Sin-Man Tsang Johnny Chun-Chau Sung Keith Wai-Yeung Kwong Tao Zheng Sharon Sze-Man Hon Ching-Po Lau Ronald Chi-Yan Ho Fang Chen Clara Bik-San Lau Ping-Chung Leung Chun-Kwok Wong Source Type: research

Investigation of the relationship between monocyte chemoattractant protein 1 rs1024611 variant and severity of COVID-19
CONCLUSION: The MCP-1 gene polymorphism had no impact on COVID-19 severity. However, to confirm these results, a large-scale study needs to be conducted.PMID:37713941 | DOI:10.1016/j.cyto.2023.156367
Source: Cytokine - September 15, 2023 Category: Molecular Biology Authors: Fatemeh Azarfar Bahareh Abbasi Amir Jalali Mohammad Hadi Abbasian Source Type: research

The efficacy of Facebook's vaccine misinformation policies and architecture during the COVID-19 pandemic
Sci Adv. 2023 Sep 15;9(37):eadh2132. doi: 10.1126/sciadv.adh2132. Epub 2023 Sep 15.ABSTRACTOnline misinformation promotes distrust in science, undermines public health, and may drive civil unrest. During the coronavirus disease 2019 pandemic, Facebook-the world's largest social media company-began to remove vaccine misinformation as a matter of policy. We evaluated the efficacy of these policies using a comparative interrupted time-series design. We found that Facebook removed some antivaccine content, but we did not observe decreases in overall engagement with antivaccine content. Provaccine content was also removed, and ...
Source: Adv Data - September 15, 2023 Category: Epidemiology Authors: David A Broniatowski Joseph R Simons Jiayan Gu Amelia M Jamison Lorien C Abroms Source Type: research

Adjuvant activities of immunostimulating natural products: Astragalus membranaceus (Fisch.) Bge and Coriolus versicolor in BNT162b2 vaccination against COVID-19 infection
In conclusion, combining AM and CV was effective in acting as an oral adjuvant with the mRNA vaccine BNT162b2 to improve the antigen binding activities against SARS-CoV-2 ancestral and variant SARS-CoV-2 spike proteins, probably via trained immunity of macrophages and dendritic cells.PMID:37713617 | DOI:10.1093/jleuko/qiad106
Source: Journal of Leukocyte Biology - September 15, 2023 Category: Hematology Authors: Ben Chung-Lap Chan Peiting Li Miranda Sin-Man Tsang Johnny Chun-Chau Sung Keith Wai-Yeung Kwong Tao Zheng Sharon Sze-Man Hon Ching-Po Lau Ronald Chi-Yan Ho Fang Chen Clara Bik-San Lau Ping-Chung Leung Chun-Kwok Wong Source Type: research

Investigation of the relationship between monocyte chemoattractant protein 1 rs1024611 variant and severity of COVID-19
CONCLUSION: The MCP-1 gene polymorphism had no impact on COVID-19 severity. However, to confirm these results, a large-scale study needs to be conducted.PMID:37713941 | DOI:10.1016/j.cyto.2023.156367
Source: Cytokine - September 15, 2023 Category: Molecular Biology Authors: Fatemeh Azarfar Bahareh Abbasi Amir Jalali Mohammad Hadi Abbasian Source Type: research

Adjuvant activities of immunostimulating natural products: Astragalus membranaceus (Fisch.) Bge and Coriolus versicolor in BNT162b2 vaccination against COVID-19 infection
In conclusion, combining AM and CV was effective in acting as an oral adjuvant with the mRNA vaccine BNT162b2 to improve the antigen binding activities against SARS-CoV-2 ancestral and variant SARS-CoV-2 spike proteins, probably via trained immunity of macrophages and dendritic cells.PMID:37713617 | DOI:10.1093/jleuko/qiad106
Source: Journal of Leukocyte Biology - September 15, 2023 Category: Hematology Authors: Ben Chung-Lap Chan Peiting Li Miranda Sin-Man Tsang Johnny Chun-Chau Sung Keith Wai-Yeung Kwong Tao Zheng Sharon Sze-Man Hon Ching-Po Lau Ronald Chi-Yan Ho Fang Chen Clara Bik-San Lau Ping-Chung Leung Chun-Kwok Wong Source Type: research

RNA nanotechnology: A new chapter in targeted therapy
Colloids Surf B Biointerfaces. 2023 Sep 6;230:113533. doi: 10.1016/j.colsurfb.2023.113533. Online ahead of print.ABSTRACTNanoparticles have been widely studied in the fields of biotechnology, pharmacy, optics and medicine and have broad application prospects. Numerous studies have shown significant interest in utilizing nanoparticles for chemically coating or coupling drugs, aiming to address the challenges of drug delivery, including degradability and uncertainty. Furthermore, the utilization of lipid nanoparticles loaded with novel coronavirus antigen mRNA to control the COVID-19 pandemic has led to a notable surge in re...
Source: Colloids and Surfaces - September 15, 2023 Category: Biotechnology Authors: Tongtong Lv Yingying Meng Yifan Liu Yukun Han Hongwu Xin Xiaochun Peng Jinbai Huang Source Type: research

Assuring the Groundwork for Success: Mentorship, Sponsorship, and Allyship for Practicing Anesthesiologists
Anesth Analg. 2023 Oct 1;137(4):754-762. doi: 10.1213/ANE.0000000000006646. Epub 2023 Sep 5.ABSTRACTThe challenges facing the health care industry in the post-coronavirus disease 2019 (COVID-19) pandemic world are numerous, jeopardizing wellness, and performance. Maintaining engagement and fulfillment of anesthesiologists in their work is now a critical issue in various practice settings: academic, private practice, and corporate medicine. In this article, we offer insights on how mentorship, sponsorship, and allyship are important in the advancement of the anesthesiology workforce including women and underrepresented mino...
Source: Anesthesia and Analgesia - September 15, 2023 Category: Anesthesiology Authors: Mofya S Diallo Crystal C Wright Alice A Tolbert Coombs Thomas R Vetter Source Type: research

Cardiac Tamponade Secondary to Hemorrhagic Pericardial Effusion: A Complication of STEMI
Conclusion: The differential for hemodynamic compromise in a patient with STEMI is broad, but quickly distinguishing pump failure from other life-threatening causes of shock is imperative to dictate time-sensitive management decisions. The presence of a hemorrhagic pericardial effusion in the setting of STEMI is a surrogate marker for a severe infarct and can help the bedside physician determine whether a patient will be better served in the catheterization lab for revascularization or in the operating room for surgical repair.PMID:37711482 | PMC:PMC10498953 | DOI:10.31486/toj.23.0023
Source: Pain Physician - September 15, 2023 Category: Anesthesiology Authors: Marvin Kajy Amy Rechenberg Connor Kerndt Kevin Wolschleger Source Type: research