Adjuvant activities of immunostimulating natural products: Astragalus membranaceus (Fisch.) Bge and Coriolus versicolor in BNT162b2 vaccination against COVID-19 infection

In conclusion, combining AM and CV was effective in acting as an oral adjuvant with the mRNA vaccine BNT162b2 to improve the antigen binding activities against SARS-CoV-2 ancestral and variant SARS-CoV-2 spike proteins, probably via trained immunity of macrophages and dendritic cells.PMID:37713617 | DOI:10.1093/jleuko/qiad106

Source: Journal of Leukocyte Biology - September 15, 2023 Category: Hematology Authors: Ben Chung-Lap Chan Peiting Li Miranda Sin-Man Tsang Johnny Chun-Chau Sung Keith Wai-Yeung Kwong Tao Zheng Sharon Sze-Man Hon Ching-Po Lau Ronald Chi-Yan Ho Fang Chen Clara Bik-San Lau Ping-Chung Leung Chun-Kwok Wong Source Type: research