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Infectious Disease: Endemics
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Total 382 results found since Jan 2013.
Successful completion of an imported fire ant cluster immunotherapy protocol
Since their introduction into Mobile, Alabama in the 1920s, imported fire ants (IFA) have slowly spread throughout across the southern United States.1-2 The leading cause of hypersensitivity in IFA endemic areas among all Hymenoptera, these venomous ants insects can cause clinical reactions ranging from localized sterile pustules and urticaria to systemic IgE-mediated reactions, including and death.3-4 Immunotherapy with IFA whole body extract (WBE) has been found to be an effective and safe treatment for IFA hypersensitivity.
Source: Annals of Allergy, Asthma and Immunology - April 23, 2019 Category: Allergy & Immunology Authors: Gloria B. Beveridge, Mike S. Tankersley Tags: Letters Source Type: research
Plasma cytokine profiles associated with rhodesiense sleeping sickness and falciparum malaria co-infection in North Eastern Uganda
Immunological Human African Trypanosomiasis (HAT) studies often exclude malaria, although both infections overlap in specific endemic areas. During this co-infection, it is not known whether this parasitic int...
Source: Allergy, Asthma and Clinical Immunology - October 30, 2019 Category: Allergy & Immunology Authors: Julius Nsubuga, Charles Drago Kato, Ann Nanteza, Enock Matovu and Vincent Pius Alibu Tags: Research Source Type: research
IJERPH, Vol. 16, Pages 4859: Mosquitoes, Infectious Diseases, and Cancer: A Connection to Study?
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Mosquitoes (Diptera: Culicidae) are vectors of pathogens and parasites of great medical and veterinary relevance. The possible association between mosquitoes, infectious diseases, and cancer has been investigated. Despite its potential importance, there is a severe lack of research data on the topic. Herein, current knowledge, tenuous links, and related challenges on the topic were examined, grouping information under four major hypotheses. The first hypothesis is that the infection of mosquito-vectored parasites, with special reference to Plasmodium spp., may lead to cancer. The International Agency for Research o...
Source: International Journal of Environmental Research and Public Health - December 2, 2019 Category: Environmental Health Authors: Carlos Brisola Marcondes Giovanni Benelli Tags: Benchmark Source Type: research
Personalized medicine for asthma in tropical regions
Purpose of review
Precision medicine could help to improve diagnosis and treatment of asthma; however, in the tropics there are special conditions to be considered for applying this strategy. In this review, we analyze recent advances of precision allergology in tropical regions, highlighting its limitations and needs in high-admixed populations living under environments with high exposure to house dust mites and helminth infections.
Recent findings
Advances have been made regarding the genetic characterization of the great diversity of populations living in the tropics. Genes involved in shared biological pathways be...
Source: Current Opinion in Allergy and Clinical Immunology - May 1, 2020 Category: Allergy & Immunology Tags: PERSONALIZED MEDICINE: Edited by Henry Milgrom and René Maximiliano Gómez Source Type: research
Major Neutralization Site of Hepatitis E Virus and Use of this Neutralization Site in Methods of Vaccination
Hepatitis E is endemic in many countries throughout the developing world, in particular on the continents of Africa and Asia. The disease generally affects young adults and has a very high mortality rate, up to 20%, in pregnant women. This invention relates to the identification of a neutralization site of hepatitis E virus (HEV) and neutralizing antibodies that react with it. The neutralization site is located on a polypeptide from the ORF2 gene (capsid gene) of HEV. This neutralization site was identified using a panel of chimpanzee monoclonal antibodies that are virtually identical to human antibodies. Since this neutra...
Source: NIH OTT Licensing Opportunities - July 6, 2020 Category: Research Authors: ott-admin Source Type: research
Risk of Zika virus transmission from mother to unborn child much higher than expected
FINDINGSAccording to a new study by UCLA researchers and colleagues conducted in Brazil, 65% of children born to mothers infected withthe Zikavirusalsotested positive for the mosquito-borneinfection— a much higher rate than expected.The findings indicatethat even babies whohave no outward neurological or other symptoms associated with Zika can still be infected with the virus andare potentially at risk offuturedevelopmental problems. BACKGROUNDThe study representsthe first time that the mother-to-child transmission rate of Zika has been reportedfor a group of children who were tracked over several years — including f...
Source: UCLA Newsroom: Health Sciences - July 27, 2020 Category: Universities & Medical Training Source Type: news
Wild Polio Sufferers Reflect as Africa Declared Free of the Disease Wild Polio Sufferers Reflect as Africa Declared Free of the Disease
Thousands across Africa still live with the effects wild polio, but an African health agency declared the region free of endemic wild polio, four years after the last case was recorded in Nigeria.Reuters Health Information
Source: Medscape Allergy Headlines - August 26, 2020 Category: Allergy & Immunology Tags: Infectious Diseases News Source Type: news
Genetic susceptibility to fungal infection in children
Purpose of review
Fungal infections have steadily increased in incidence, emerging as a significant cause of morbidity and mortality in patients with iatrogenic immunosuppression. Simultaneously, we have witnessed a growing population of newly described inherited immune disorders that have enhanced our understanding of the human immune response against fungi. In the present review, we provide an overview and diagnostic roadmap to inherited disorders which confer susceptibility to superficial and invasive fungal infections.
Recent findings
Inborn errors of fungal immunity encompass a heterogeneous group of disord...
Source: Current Opinion in Pediatrics - November 11, 2020 Category: Pediatrics Tags: ALLERGY, IMMUNOLOGY AND RELATED DISORDERS: Edited by Jordan S. Orange Source Type: research
M255 multifocal cerebral abscesses and pulmonary cavitary lesions in a male with altered mental status
Histoplasma is endemic in the Ohio-Mississippi River Valley. Most immunocompetent patients are asymptomatic; invasive disease warrants concern for primary or secondary immune defects. Concomitant bacterial infection leading to multiple cerebral abscesses in the setting of pulmonary histoplasmosis has not been reported.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2020 Category: Allergy & Immunology Authors: S. Kesh, K. Guarnieri, I. Slack, E. Kellner Source Type: research
Identification of a New Human Monoclonal Antibody that More Potently Prevents Malaria Infection
Malaria is a major disease caused by a parasite transmitted through the bite of infected female mosquitoes. Globally, an estimated 214 million cases of malaria and 438,000 deaths from malaria occur annually, with chidren in African and South Asian regions being most vulnerable. Approximately 1,500-2,000 cases of malaria are reported in the United States each year, mostly in returning travelers from malaria- endemic countries. Among the international travelers, military personnel, diplomats, pregnant women, children and older individuals with weakened immune systems are more likely to be at risk of malaria infection and mor...
Source: NIH OTT Licensing Opportunities - November 13, 2020 Category: Research Authors: ott-admin Source Type: research
We May Never Eliminate COVID-19. But We Can Learn to Live With It
When does a pandemic end? Is it when life regains a semblance of normality?
Is it when the world reaches herd immunity, the benchmark at which enough people are immune to an infectious disease to stop its widespread circulation? Or is it when the disease is defeated, the last patient cured and the pathogen retired to the history books?
The last scenario, in the case of COVID-19, is likely a ways off, if it ever arrives. The virus has infected more than 100 million people worldwide and killed more than 2 million. New viral variants even more contagious than those that started the pandemic are spreading across the world. And...
Source: TIME: Health - February 4, 2021 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Cover Story COVID-19 feature Magazine Source Type: news
Microbiological profile in chronic granulomatous disease patients in a single Brazilian primary immunodeficiency center
CONCLUSION: Staphylococcus sp., Staphylococcus aureus, and Aspergillus sp. were the most frequent agents found in this cohort. M. tuberculosis should be considered in endemic area. Detection of infectious agents drives to the adequate treatment and benefits the evolution of patients with CGD.PMID:33641311 | DOI:10.15586/aei.v49i2.82
Source: Allergologia et Immunopathologia - February 28, 2021 Category: Allergy & Immunology Authors: Aim ée Filippini Bifulco Oliveira Antonio Carlos Pastorino Mayra de Barros Dorna Ana Paula Beltran Moschione Castro Jos é Roberto Mendes Pegler Beni Morgenstern Magda Maria Sales Carneiro-Sampaio Source Type: research
