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Impact of IgE-mediated Food Allergy on Parental Quality of Life in Iranian Patients.
Abstract Food allergy is a common disorder especially in the first years of life. Strict avoidance of the responsible food is the most effective therapeutic measure so far. But this continuous vigilance could be stressful for the patient and family and decreases their quality of life (QOL). This survey was designed to evaluate the impact of IgE-mediated food allergy on parental QOL in Iranian patients and to develop a valid Persian version of "Food Allergy Quality Of Life- Parental Burden (FAQL-PB) questionnaire". 90 patients (28 females, 62 males) and their parents who were referred to the clinic of Allergy in Ch...
Source: Iranian Journal of Allergy, Asthma and Immunology - September 30, 2016 Category: Allergy & Immunology Authors: Fathi SM, Tavakol M, Rezaei N, Movahedi M, Aghamohammadi A, Shariat M, Sadeghi B, Behniafard N, Darabi B, Hajikhani A, Abdollahpour I, Gharagozlou M Tags: Iran J Allergy Asthma Immunol Source Type: research

Spontaneous food allergy in Was ‐/‐ mice occurs independent of FcεRI‐mediated mast cell activation
ConclusionsWas‐/‐ mice provide a model of food allergy with the advantage of mimicking polysensitization and low food‐antigen IgE titers as observed in humans with clinical food allergy. This model will facilitate studies on aberrant immune responses during spontaneous disease development. Our results imply that therapeutic targeting of the IgE/FcεRI activation cascade will not affect sensitization to food.This article is protected by copyright. All rights reserved.
Source: Allergy - June 10, 2017 Category: Allergy & Immunology Authors: Willem S. Lexmond, Jeremy A. Goettel, Benjamin F. Sallis, Katelyn McCann, Edmond H. H. M. Rings, Erika Jensen ‐Jarolim, Samuel Nurko, Scott B. Snapper, Edda Fiebiger Tags: Original Article: Experimental Allergy and Immunology Source Type: research

Meat allergy associated with α‐Gal – Closing diagnostic gaps by anti‐α‐Gal IgE immune profiling
ConclusionsDetection of individual sensitization patterns with different α‐Gal‐containing analytes provides the basis for an individual allergy diagnosis for α‐Gal sensitized patients. Higher amounts of α‐Gal in pork and beef innards compared to muscle meat as indicated by a higher staining intensity are a plausible explanation for the difference in allergic symptom severity.This article is protected by copyright. All rights reserved.
Source: Allergy - July 3, 2017 Category: Allergy & Immunology Authors: U. Jappe, S. Minge, B. Kreft, A. Ludwig, B. Przybilla, A. Walker, R. Varga, P. Seidel, T. Biedermann, W. Anem üller, A. Kromminga, F. Ruëff, H. Merk, N. Wagner, R. Treudler, M. Worm, I. Waldmann, J. Saloga, W. M. Becker, T. Goldmann, T. A. Platts‐Mill Tags: Original Article: Experimental Allergy and Immunology Source Type: research

The Efficacy of Oral Immunotherapy in Patients with Cow's Milk Allergy.
Abstract Cow's milk allergy is the most common type of food allergy that decrease the quality of life of patients and their families. The aim of this study was to evaluate the efficacy of oral immunotherapy in patients with cow's milk allergy. 14 patients above 3 years of age with a history of cow's milk allergy confirmed by positive double blind placebo controlled food challenge (DBPCFC) test, presence of serum IgE against cow's milk and positive SPT (skin prick test) were enrolled in this study. During the immunotherapy all patients received increasing amounts of cow's milk during three phases. The type and seve...
Source: Iranian Journal of Allergy, Asthma and Immunology - June 1, 2017 Category: Allergy & Immunology Authors: Ebrahimi M, Gharagozlou M, Mohebbi A, Hafezi N, Azizi G, Movahedi M Tags: Iran J Allergy Asthma Immunol Source Type: research

Cypress pollen allergy is responsible for two distinct phenotypes of allergic rhinitis different from other pollinosis.
Authors: Pahus L, Gouitaa M, Sofalvi T, Alagha K, Gras D, Chanez P, Charpin D Abstract Summary: Different phenotypes of allergic rhinitis have been identified based on the seasonality of the allergen involved. Within pollinosis, importance has to be paid to the responsible pollen species. Guidelines for clinical management are mostly based on studies performed in patients with grass pollen allergy. Only few data is available on tree pollen allergy and more specifically on cypress pollen allergy. We focused on the clinical and biological features of cypress pollen allergy to determine whether it is associated with a...
Source: European Annals of Allergy and Clinical Immunology - January 21, 2018 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Oral allergy syndrome amongst young Mexicans: prevalence and associated factors.
Conclusions. Notably, the prevalence of OAS varies according to the geographic area. Personal histories of allergy to pollen or latex were the main factors linked to OAS. PMID: 29533053 [PubMed - as supplied by publisher]
Source: European Annals of Allergy and Clinical Immunology - March 15, 2018 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Systematic review of professional liability when prescribing beta-lactams for patients with a known penicillin allergy.
CONCLUSION: The cases with published legal outcomes found limited professional liability for clinicians who prescribed either cephalosporins or carbapenems to a patient with a known penicillin allergy. These results may decrease the litigation fears of providers and risk managers within healthcare systems. PMID: 29551402 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - March 15, 2018 Category: Allergy & Immunology Authors: Jeffres MN, Hall-Lipsy EA, King ST, Cleary JD Tags: Ann Allergy Asthma Immunol Source Type: research

Leaving the nest: improving food allergy management on college campuses.
CONCLUSION: The use of qualitative research methods, patient-centered design processes, and collaborations with diverse stakeholders-including pediatricians that care for adolescents-can provide a framework for designing coordinated systems and policies to provide comprehensive support to college students with food allergy. Next steps include rigorously testing implementation of the Spotlight intervention prototypes. PMID: 29679763 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - April 18, 2018 Category: Allergy & Immunology Authors: Dyer AA, O'Keefe A, Kanaley MK, Kao L, Gupta RS Tags: Ann Allergy Asthma Immunol Source Type: research

The Basophil Activation Test reduces the need for a food challenge test in children suspected of IgE ‐mediated cow's milk allergy
Conclusions and Clinical RelevanceThe BAT seems reliable and cost ‐effective to diagnose patients with an IgE‐mediated cow's milk allergy. In IgE sensitized patients a BAT might replace a DBPCFC. For non‐IgE sensitized patients presenting with mild symptoms we propose to consider a (double‐blind) extended (time) challenge test at home.This article is protected by copyright. All rights reserved.
Source: Clinical and Experimental Allergy - November 8, 2018 Category: Allergy & Immunology Authors: Janneke Ruinemans ‐Koerts, Yvonne Schmidt‐Hieltjes, A d Jansen, Huub F.J. Savelkoul, Annejet Plaisier, Petra van Setten Tags: Original Article ‐Clinical Allergy Source Type: research

Cross-elicitation responses to 2-methoxymethyl-p-phenylenediamine in p-phenylenediamine highly allergic volunteers using allergy alert test: the Italian experience.
Conclusions. Me-PPD may offer a safer alternative for PPD-allergic patients with an absent or reduced elicitation response in the allergy alert test simulating hair dye use conditions. Even patients with strong patch test reactions, with appropriate selection by allergy alert test and counselling, may be able to tolerate hair dyeing with Me-PPD containing products. PMID: 30702234 [PubMed - as supplied by publisher]
Source: European Annals of Allergy and Clinical Immunology - February 2, 2019 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Hyperresponsiveness to Boiled Egg Yolk in Early Life Leads to Prolonged Egg Allergy.
Authors: Horino S, Kitazawa H, Satou T, Miura K Abstract Hen's egg is the most common allergen in IgE-mediated food allergy among children in Japan. Although the majority of patients with egg allergy can eat heated egg yolk safely because of its low allergenicity, severely allergic patients show an immediate-type reaction to heated egg yolk. We hypothesized that patients with hyperresponsiveness to boiled egg yolk may have difficulty in acquiring tolerance to egg. The purpose of this study was to examine the prognosis of patients with hyperresponsiveness to boiled egg yolk. Data from 121 patients with egg allergy w...
Source: Allergy, Asthma and Immunology Research - March 27, 2019 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

An update on shellfish allergy
Purpose of review Shellfish is an important cause of food allergy worldwide, and a major cause of food-triggered anaphylaxis. Despite the wide variety of shellfish, there is considerable serological and clinical cross-reactivity of major shellfish allergens, and accurate diagnosis remains a challenge in the management of shellfish allergy. Recent findings Novel minor allergens have been discovered and characterized, and advances in component resolved diagnostics have provided insights into the prevalence of sensitization and their clinical importance in shellfish allergy. The extensive cross-reactivity between tropomy...
Source: Current Opinion in Allergy and Clinical Immunology - April 30, 2019 Category: Allergy & Immunology Tags: FOOD ALLERGY: Edited by Alessandro Fiocchi and Motohiro Ebisawa Source Type: research

Occupational allergy to dog among police dog trainers.
This study was aimed to reveal the prevalence of dog allergy and other common allergy and allergic symptoms in police dog trainers. Fifty-six police dog trainers and 150 workers as control group were included in this study. Medical records of dog trainers including respiratory, skin, eye symptoms and physical examinations and skin prick test results are compared with the medical records of control group. Positive SPT to dog was present in 21.4% of dog trainers, whereas the frequency of sensitization to dog in the control group was 1.3% (p minor 0.001). Dog allergy development risk is found 20 times greater in dog trainers ...
Source: European Annals of Allergy and Clinical Immunology - July 11, 2019 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Clinical Features and Culprit Food Allergens of Korean Adult Food Allergy Patients: A Cross-Sectional Single-Institute Study.
CONCLUSIONS: Wheat, fruits with or without PFAS, and crustaceans are important and frequent causative allergens in Korean adult FA; these allergens differ from those found in childhood FA. It is notable that non-classic allergies, such as PFAS, FDEIA, and α-Gal allergy, are the important causes of anaphylaxis in Korean adult FA. PMID: 31332982 [PubMed]
Source: Allergy, Asthma and Immunology Research - July 25, 2019 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Drug allergy is associated with the development of extraintestinal manifestations in patients with ulcerative colitis.
Authors: Toledo-Maurino JJ Abstract Summary: Drug allergies are developed by antibody or cell-mediated reactions as immunologic mechanisms. It has been demonstrated that hypersensitivity reaction to certain allergens may play a role in the pathogenesis of inflammatory bowel disease (IBD) focused on food allergies. A total of 256 patients with UC were divided in two groups: 203 patients with active UC and 53 in remission UC were included in the present study. In the present study we found that 11.7% had allergy to at least one drug distributed. The most frequent drug-allergies were sulfonamides in 2.8% and penicilli...
Source: European Annals of Allergy and Clinical Immunology - October 10, 2019 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research