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Total 303 results found since Jan 2013.

NIAID meeting report: Improving malaria vaccine strategies through the application of immunological principles.
This report summarizes the discussion and major recommendations generated by the workshop participants regarding the application of recent advances in basic immunology and state-of-the-art immunological tools to improve progress and help address current challenges and knowledge gaps in malaria vaccine development. PMID: 24060568 [PubMed - as supplied by publisher]
Source: Vaccine - September 20, 2013 Category: Allergy & Immunology Authors: Mo AX, Augustine AD Tags: Vaccine Source Type: research

Primary Immune Deficiency Treatment Consortium (PIDTC) report
The Primary Immune Deficiency Treatment Consortium (PIDTC) is a network of 33 centers in North America that study the treatment of rare and severe primary immunodeficiency diseases. Current protocols address the natural history of patients treated for severe combined immunodeficiency (SCID), Wiskott-Aldrich syndrome, and chronic granulomatous disease through retrospective, prospective, and cross-sectional studies. The PIDTC additionally seeks to encourage training of junior investigators, establish partnerships with European and other International colleagues, work with patient advocacy groups to promote community awarenes...
Source: Journal of Allergy and Clinical Immunology - October 17, 2013 Category: Allergy & Immunology Authors: Linda M. Griffith, Morton J. Cowan, Luigi D. Notarangelo, Donald B. Kohn, Jennifer M. Puck, Sung-Yun Pai, Barbara Ballard, Sarah C. Bauer, Jack J.H. Bleesing, Marcia Boyle, Amy Brower, Rebecca H. Buckley, Mirjam van der Burg, Lauri M. Burroughs, Fabio Can Tags: Workshop summary Source Type: research

Advances in the risk management of unintended presence of allergenic foods in manufactured food products - an overview.
Abstract Food allergy is a relatively recent newcomer to the ranks of food safety issues, only being effectively recognised as such in the last 25 to 30 years. This recognition, allied with the near impossibility of avoiding the unintended presence of small, yet potentially dangerous residues of allergenic constituents, brought with it the need to assess and manage the resulting risk. This paper provides an overview of the development and current knowledge and thinking on risk assessment and its application to risk management of food allergens. It also discusses the associated challenges, in particular those aroun...
Source: Food and Chemical Toxicology - February 6, 2014 Category: Food Science Authors: Hattersley S, Ward R, Baka A, Crevel RW Tags: Food Chem Toxicol Source Type: research

Myasthenia in pregnancy: best practice guidelines from a UK multispecialty working group
A national UK workshop to discuss practical clinical management issues related to pregnancy in women with myasthenia gravis was held in May 2011. The purpose was to develop recommendations to guide general neurologists and obstetricians and facilitate best practice before, during and after pregnancy. The main conclusions were (1) planning should be instituted well in advance of any potential pregnancy to allow time for myasthenic status and drug optimisation; (2) multidisciplinary liaison through the involvement of relevant specialists should occur throughout pregnancy, during delivery and in the neonatal period; (3) provi...
Source: Journal of Neurology, Neurosurgery and Psychiatry - April 10, 2014 Category: Neurosurgery Authors: Norwood, F., Dhanjal, M., Hill, M., James, N., Jungbluth, H., Kyle, P., O'Sullivan, G., Palace, J., Robb, S., Williamson, C., Hilton-Jones, D., Nelson-Piercy, C. Tags: Immunology (including allergy), Neuromuscular disease Source Type: research

Reply
The correspondence from Chipps et al highlights a new questionnaire for preschool children titled the “Test for Respiratory and Asthma Control in Kids” (TRACK). Although our recent review on childhood asthma indeed stated that “there are no instruments available [for asthma control] for children in the 0- to 4-year age group,” that statement was adapted from the recent National Institutes of Health and the Agency for Healthcare Research and Quality Asthma Outcomes Workshop Report, which identified no core or supplemental measures for baseline characterization or prospective efficacy analyses in children younger th...
Source: Journal of Allergy and Clinical Immunology - May 1, 2014 Category: Allergy & Immunology Authors: Stanley J. Szefler, James F. Chmiel, Anne M. Fitzpatrick, George Giacoia, Thomas P. Green, Daniel J. Jackson, Heber C. Nielsen, Wanda Phipatanakul, Hengameh H. Raissy Tags: Correspondence Source Type: research

Birth cohorts in asthma and allergic diseases: Report of a NIAID/NHLBI/MeDALL joint workshop
Source: Journal of Allergy and Clinical Immunology - March 15, 2014 Category: Allergy & Immunology Authors: Jean Bousquet, James E. Gern, Fernando D. Martinez, Josep M. Anto, Christine C. Johnson, Patrick G. Holt, Robert F. Lemanske, Peter N. Le Souëf, Robert S. Tepper, Erika R.M. von Mutius, S. Hasan Arshad, Leonard B. Bacharier, Allan Becker, Kathleen Belang Tags: Workshop summary Source Type: research

Assessing the validity of the RAND Negative Impact of Asthma on Quality of Life Short Forms
In response to recommendations from the 2010 National Institutes of Health Asthma Outcomes Workshop, we developed a system for measuring the negative impact of asthma on quality of life (QoL), which was referred to as the RAND Negative Impact of Asthma on Quality of Life (RAND-IAQL) item bank. The bank contains 65 items that focus on the patient's perception of the impact or bother of asthma on his or her life.
Source: Journal of Allergy and Clinical Immunology - April 21, 2014 Category: Allergy & Immunology Authors: Cathy D. Sherbourne, Brian D. Stucky, Maria Orlando Edelen, Nicole K. Eberhart, Eric Kleerup, Marielena Lara Tags: Asthma and lower airway disease Source Type: research

Symptom dynamics during repeated serial allergen challenge chamber exposures to house dust mite
The proceedings of a National Institutes of Health workshop and a meeting of an Advisory Committee of the US Food and Drug Administration,1,2 as well as related commentaries,3,4 highlight the utility of an allergen challenge chamber (ACC) for conducting clinical trials for allergic rhinoconjunctivitis (AR). Mitigation of factors that might confound the design, analysis, and interpretation of these trials requires a systematic comparison of symptoms present in the natural setting versus those elicited after exposure to aeroallergens in an ACC.
Source: Journal of Allergy and Clinical Immunology - November 11, 2014 Category: Allergy & Immunology Authors: Robert L. Jacobs, Charles P. Andrews, Daniel A. Ramirez, Cynthia G. Rather, Nathan Harper, Fabio Jimenez, Hernan Martinez, Muthu Manoharan, Andrew Carrillo, Margit Gerardi, Robert E. Esch, Weijing He, Sunil K. Ahuja Tags: Letter to the Editor Source Type: research

Roseoloviruses: unmet needs and research priorities
Publication date: December 2014 Source:Current Opinion in Virology, Volume 9 Author(s): Mary T Caserta , Laurie T Krug , Philip E Pellett The human roseoloviruses, human herpesviruses 6A (HHV-6A), HHV-6B, and HHV-7, are highly prevalent viruses that typically cause fever/rash illnesses such as roseola during early life primary infections. They also cause significant neurologic disease and complications following stem cell and solid organ transplantation, and have suggestive but less certain etiologic associations with other neurologic diseases and immunologic disorders. The US National Institute of Allergy and Infectious...
Source: Current Opinion in Virology - November 16, 2014 Category: Virology Source Type: research

Roseoloviruses: unmet needs and research priorities Perspective
Publication date: December 2014 Source:Current Opinion in Virology, Volume 9 Author(s): Mary T Caserta , Laurie T Krug , Philip E Pellett The human roseoloviruses, human herpesviruses 6A (HHV-6A), HHV-6B, and HHV-7, are highly prevalent viruses that typically cause fever/rash illnesses such as roseola during early life primary infections. They also cause significant neurologic disease and complications following stem cell and solid organ transplantation, and have suggestive but less certain etiologic associations with other neurologic diseases and immunologic disorders. The US National Institute of Allergy and Infectious...
Source: Current Opinion in Virology - November 27, 2014 Category: Virology Source Type: research

Workshop Webcast: Immunology of Protection from Ebola Virus Infection
Friday, December 12th, 8:00 am – 5:30 pm ET The Food and Drug Administration (FDA), the National Institutes of Allergy and Infectious Diseases (NIAID), the Department of Defense (DoD), the Centers for Disease Control and Prevention (CDC), and the Biomedical Advanced Research and Development Authority (BARDA) are co-sponsoring a workshop, entitled “Immunology of Protection from […]
Source: NN/LM Middle Atlantic Region Blog - December 5, 2014 Category: Databases & Libraries Authors: mjharvey Tags: Disaster / Emergency Preparedness Education Outreach Public Health Source Type: news

Progress Toward Curing HIV Infections With Hematopoietic Stem Cell Transplantation
Combination antiretroviral therapy can suppress human immunodeficiency virus (HIV) infection but cannot completely eradicate the virus. A major obstacle in the quest for a cure is the difficulty in targeting and measuring latently infected cells. To date, a single person seems to have been cured of HIV. Hematopoietic stem cell transplantation (HSCT) preceded this cancer patient's long-term sustained HIV remission, but researchers have been unable to replicate this cure, and the mechanisms that led to HIV remission remain to be established. In February 2014, the National Institute of Allergy and Infectious Diseases sponsore...
Source: Clinical Infectious Diseases - December 23, 2014 Category: Infectious Diseases Authors: Smiley, S. T., Singh, A., Read, S. W., Sharma, O. K., Finzi, D., Lane, C., Rice, J. S. Tags: HIV/AIDS Source Type: research

Coping with catastrophe: the value of endoscopic vascular injury training
ConclusionThe Vascular Injuries Workshop arms surgeons with a structured approach to managing the surgical field and provides effective hemostatic techniques in the face of impending catastrophe. In comparison to the existing literature on ICA rupture, our results show trained surgeons are well equipped to achieve safe outcomes for their patients.
Source: International Forum of Allergy and Rhinology - December 29, 2014 Category: Allergy & Immunology Authors: Vikram Padhye, Rowan Valentine, Raymond Sacks, Eng H. Ooi, Charlie Teo, Marc Tewfik, Dehui Wang, Peter‐John Wormald Tags: ORIGINAL ARTICLE Source Type: research

A workshop report on the development of the Cow's Milk‐related Symptom Score awareness tool for young children
ConclusionThe CoMiSS provides primary healthcare clinicians with a simple, fast and easy‐to‐use awareness tool for cow's milk related symptoms This article is protected by copyright. All rights reserved.
Source: Acta Paediatrica - December 30, 2014 Category: Pediatrics Authors: Yvan Vandenplas, Christophe Dupont, Philippe Eigenmann, Arne Host, Mikael Kuitunen, Carmen Ribes‐Koninck, Neil Shah, Raanan Shamir, Annamaria Staiano, Hania Szajewska, Andrea Von Berg Tags: Committee Report Source Type: research