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Drug: Insulin

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Experiences of Attending Group Education to Support Insulin Initiation in Type 2 Diabetes: A Qualitative Study
ConclusionPositive experiences of insulin group education for people with type 2 diabetes were associated with sharing experiences with other people starting insulin, reassurance from healthcare professionals, appropriate supportive materials, and skill of the facilitator to address insulin concerns and manage group dynamics. People with type 2 diabetes may benefit more from education if healthcare professionals are skilled in psychological techniques to facilitate group education aimed at addressing concerns around insulin therapy. Further research needs to assess the effectiveness of structured insulin group education fo...
Source: Diabetes Therapy - December 31, 2019 Category: Endocrinology Source Type: research

The insulin sharps disposal study: Evaluation of a structured patient education initiative in an urban community health centre in India
CONCLUSIONS: PIHE over an 18-month period for diabetic patients on insulin significantly improved knowledge and practises relating to insulin use and correct disposal of syringes and sharps.PMID:33681058 | PMC:PMC7928141 | DOI:10.4103/jfmpc.jfmpc_1295_20
Source: Primary Care - March 8, 2021 Category: Primary Care Authors: Kusum V Moray K Manjunath A J Martina Shalini Ruby Angeline Pricilla S Sushil Mathew John Jasmin Helen Prasad Source Type: research

Effects of physician ’s diabetes self‐management education using Japan Association of Diabetes Education and Care Diabetes Education Card System Program and a self‐monitoring of blood glucose readings analyzer in individuals with type 2 diabetes: An exploratory, open‐labeled, prospective randomized clinical tria l
ConclusionGreater HbA1c-lowering by physicians ’ diabetes self-management education using the Japan Association of Diabetes Education and Care education tool and SMBG analyzer in individuals with type 2 diabetes receiving insulin and SMBG was suggested, but not confirmed.
Source: Journal of Diabetes Investigation - July 31, 2021 Category: Endocrinology Authors: Nagaaki Tanaka, Daisuke Yabe, Kenta Murotani, Yuko Yamaguchi, Yuki Fujita, Sodai Kubota, Rena Nakashima ‐Yasuda, Saki Kubota‐Okamoto, Shinji Ueno, Yuji Yamazaki, Hitoshi Kuwata, Koin Watanabe, Takanori Hyo, Yoshiyuki Hamamoto, Takeshi Ku Tags: Original Article Source Type: research

A chemoinformatics search for peroxisome proliferator-activated receptors ligands revealed a new pan-agonist able to reduce lipid accumulation and improve insulin sensitivity
Eur J Med Chem. 2022 Mar 16;235:114240. doi: 10.1016/j.ejmech.2022.114240. Online ahead of print.ABSTRACTThe peroxisome proliferator-activated receptors (PPARs) are nuclear receptors involved in the regulation of the metabolic homeostasis and therefore represent valuable therapeutic targets for the treatment of metabolic diseases. The development of more balanced drugs interacting with PPARs, devoid of the side-effects showed by the currently marketed PPARγ full agonists, is considered the major challenge for the pharmaceutical companies. Here we present a chemoinformatics search approach for new ligands that let us ident...
Source: European Journal of Medicinal Chemistry - March 24, 2022 Category: Chemistry Authors: Sabina Sblano Carmen Cerchia Antonio Laghezza Luca Piemontese Leonardo Brunetti Rosalba Leuci Federica Gilardi Aurelien Thomas Massimo Genovese Alice Santi Paolo Tortorella Paolo Paoli Antonio Lavecchia Fulvio Loiodice Source Type: research

Socioeconomic deprivation is associated with reduced efficacy of an insulin adjustment education program for people with type 1 diabetes
CONCLUSION: Socioeconomic deprivation was associated with higher baseline mean HbA1c and lower reduction in HbA1c following DAFNE education. Future research could explore causes and how best to support participants from deprived areas.PMID:35716029 | DOI:10.1111/dme.14902
Source: Molecular Medicine - June 18, 2022 Category: Molecular Biology Authors: Callum W D Innes David E Henshall Blair Wilson Michael T C Poon Steven D Morley Stuart A Ritchie Source Type: research

90% of doctors 'support Liverpool Care Pathway'
Conclusion A key issue raised by doctors in this survey was a need for extra training in assessing and recognising when people are coming to the end of their lives. Around a quarter of surveyed palliative medicine consultants felt that doctors needed more training to help them recognise that a patient was dying, and in how to communicate this to them and their relatives. As one consultant said: “There are undoubtedly cases reported in the press where end of life care has not been managed well. These should be criticisms of training, assessment and common sense. They are not correctly directed at the pathway. “It is as ...
Source: NHS News Feed - March 1, 2013 Category: Consumer Health News Tags: Older people QA articles Medical practice Source Type: news

Nutritional Factors and Preservation of C-Peptide in Youth With Recently Diagnosed Type 1 Diabetes: SEARCH Nutrition Ancillary Study.
CONCLUSIONS Increased intake of branched-chain amino acids and long-chain omega-3 fatty acids may support preservation of β-cell function. This represents a new direction for research to improve prognosis for type 1 diabetes. PMID: 23801797 [PubMed - in process]
Source: Diabetes Care - July 1, 2013 Category: Endocrinology Authors: Mayer-Davis EJ, Dabelea D, Crandell JL, Crume T, D'Agostino RB, Dolan L, King IB, Lawrence JM, Norris JM, Pihoker C, The N Tags: Diabetes Care Source Type: research

PILL series. Diabetes mellitus: the first visit.
Abstract Diabetes mellitus is an 'insulin problem' as the maintenance of normoglycaemia is affected by either reduced pancreatic insulin production or cellular insulin resistance. During a patient's first visit for type 2 diabetes mellitus, there are several consultation tasks that the doctor should consider. First, the doctor has to disclose the diagnosis. Second, there is a need to correct any myths and misconceptions that the patient may have on the disease. Next, to allow the doctor to provide patient-specific disease education and advice on lifestyle modifications and goal setting, the biopsychosocial impact ...
Source: Singapore Medical Journal - July 1, 2013 Category: Journals (General) Authors: Tan G, De Roza J, Chen YT, How CH Tags: Singapore Med J Source Type: research

Implementing Diabetes Care Guidelines in Long Term Care
Conclusion: This narrative review points to the need for continued work in the application of evidence-based guidelines in long term care, specifically in the area of interventions that must be adjusted to the needs of the nursing home population, with increased awareness in maintaining or improving quality of life.
Source: Journal of the American Medical Directors Association - August 1, 2013 Category: Health Management Authors: Kathy K. Hager, Paul Loprinzi, Dennis Stone Tags: Original Studies Source Type: research

Efficacy and safety of insulin treatment in type 2 diabetes using a new index called glucose safety control index.
CONCLUSION: According to the GSCI ratio, long-acting basal insulin therapy tended to be superior to NPH therapy, oral hypoglycemic agents plus basal insulin therapy tended to be superior to premixed insulin therapy, noninsulin antidiabetic agents and premixed insulin therapy was comparable, and basal-bolus insulin therapy tended to be superior to premixed insulin therapy in type 2 diabetes. PMID: 24229692 [PubMed - in process]
Source: Chinese Medical Journal - November 1, 2013 Category: Journals (General) Authors: Cai XL, Luo YY, Han XY, Ji LN Tags: Chin Med J (Engl) Source Type: research

The use of glyburide in the management of gestational diabetes mellitus: A meta-analysis.
CONCLUSIONS: Our study suggested that in women with GDM, glyburide is as effective as insulin, but the risks of neonatal hypoglycemia, high fetal birth weight, and macrosomia were higher. PMID: 24797983 [PubMed - in process]
Source: Advances in Medical Sciences - March 1, 2014 Category: Biomedical Science Authors: Zeng YC, Li MJ, Chen Y, Jiang L, Wang SM, Mo XL, Li BY Tags: Adv Med Sci Source Type: research

Acute respiratory distress syndrome following intralipid emulsion therapy
2.5 out of 5 stars Acute respiratory distress syndrome following verapamil overdose treated with intravenous lipid emulsion; A rare life-threatening complication. Martin C et al.  Ann Fr Anesth Reanim 2014 [Epub ahead of print] Reference This interesting French case report is a textbook example of how not to use intralipid emulsion therapy (ILE) in calcium-channel-block (CCB) overdose. It describes a 51-year-old woman who present to the emergency room 8 hours after ingesting forty 240 mg verapamil, a total of 9.6 grams. She was hypotensive and bradycardic, although alert and oriented. Initial echocardiography showed goo...
Source: The Poison Review - July 12, 2014 Category: Toxicology Authors: Leon Tags: Medical adverse drug reaction calcium channel blocker overdose intralipid emulsion therapy verapamil Source Type: news