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Drug: Methotrexate

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Total 6619 results found since Jan 2013.

Primary Central Nervous System Lymphoma: Clinical Characteristics, Treatment Options and Therapeutic Outcome in 36 Patients. A Single Center Experience
CONCLUSIONS: A difference in CR and PFS favored a more aggressive protocol, but the toxicity of the multiagent combinations was significantly higher. The prognosis in younger was better than in older patients, with higher rates of CR, PFS, and OS, although not statistically significant. Overall treatment outcomes are encouraging; however, there is a real need for an adaptive approach for older patients and balancing among the effectiveness and side effects.PMID:36309861
Source: The Israel Medical Association Journal - October 30, 2022 Category: General Medicine Authors: Miri Zektser Anat Rabinovich Uri Grinbaum Tzvi Porges Aya Gozlan Anna Gourevitch Kayed Al-Athamen Orit Barrett Ido Peles Tehila Kaisman-Elbaz Etai Levi Source Type: research

Hidradenitis suppurativa: A practical review of possible medical treatments based on over 350 hidradenitis patients.
This article centers on medical therapies and will only passingly mention surgical and laser treatments. This article summarizes my treatment experience with over 350 HS patients. PMID: 24021361 [PubMed - in process]
Source: Dermatol Online J - September 16, 2013 Category: Dermatology Authors: Scheinfeld N Tags: Dermatol Online J Source Type: research

Use of telemedicine for providing medical abortion
Telemedicine has been used to provide abortion in several ways. The website Women on Web uses e-mail support to facilitate the provision of medical abortion to women in situations in which safe abortion is not available . Some US clinics offer medical abortions in which the patients see a counselor in the clinic but see the doctor via videoconferencing . Routine ultrasound is usually used to date the pregnancy and determine abortion success in North America but serial quantitative human chorionic gonadotropin (hCG) values can also be used . Because mifepristone is not available in Canada, the usual regimen is methotrexate ...
Source: International Journal of Gynaecology and Obstetrics - December 12, 2013 Category: OBGYN Authors: Ellen R. Wiebe Tags: Brief Communications Source Type: research

Examining the management of muscle-invasive bladder cancer by medical oncologists in the United States.
CONCLUSIONS: Most MedOncs (79%) in this survey offer perioperative chemotherapy to all patients with MIBC. This increased use of NACT is higher than previously reported, suggesting an increase in the adoption of recommendations that follow best evidence. PMID: 24840869 [PubMed - as supplied by publisher]
Source: Urologic Oncology - May 16, 2014 Category: Urology & Nephrology Authors: Apolo AB, Kim JW, Bochner BH, Steinberg SM, Bajorin DF, Kevin Kelly W, Agarwal PK, Koppie TM, Kaag MG, Quinn DI, Vogelzang NJ, Sridhar SS Tags: Urol Oncol Source Type: research

Combining Biologic Therapies With Other Systemic Treatments in Psoriasis Evidence-Based, Best-Practice Recommendations From the Medical Board of the National Psoriasis Foundation
Conclusions and RelevanceAmong appropriately selected patients with psoriasis, carefully chosen combinations may result in greater efficacy, while minimizing toxicity.
Source: JAMA Dermatology - December 17, 2014 Category: Dermatology Source Type: research

Novel Medical Therapy of Cesarean Scar Pregnancy With a Viable Embryo Combining Multidose Methotrexate and Mifepristone: A Case Report
We present a case of CSP with a viable embryo that was successfully treated with a novel medical therapy combining multidose methotrexate (MTX) and mifepristone. No further additional invasive procedure was required since pregnancy products were dissolved and no major complications were experienced. Multidose MTX and mifepristone can be considered a safe and effective treatment for CSP.
Source: Medicine - October 1, 2015 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Medical management of an ovarian ectopic pregnancy: a case report
Conclusions: Ectopic ovarian pregnancy is a very important medical situation. It should be diagnosed in its early stages otherwise it could be life-threatening and surgical treatment may be inevitable. Because of the importance of fertility, medical treatment is an acceptable option and can be feasible with early diagnosis.
Source: Epidemiologic Perspectives and Innovations - December 20, 2015 Category: Epidemiology Authors: Ozer BirgeMustafa ErkanErtugrul OzbeyDeniz Arslan Source Type: research

Update on the prevalence and incidence of rheumatoid arthritis in Korea and an analysis of medical care and drug utilization
The objectives of this study are to identify the prevalence and incidence of rheumatoid arthritis (RA) and to investigate the patterns of medical care and drug utilization by RA patients in Korea. Korean National Health Insurance claims data were used for analysis. RA patients were defined as those having an RA code from 2009 to 2012 and using disease-modifying anti-rheumatic drugs (DMARDs) within 1  year after the code. RA patients identified in 2010 with a disease-free period for 12 months before the index date, and those who received continuous treatment in 2011–2013 were defined as incident cases. Patterns of medic...
Source: Rheumatology International - January 4, 2018 Category: Rheumatology Source Type: research

Prevalence of high-risk drug-drug interactions in paediatric inpatients: a retrospective, single-centre cohort analysis.
CONCLUSIONS: The low prevalence of contraindicated DDIs suggests that Pharmavista® has a low risk of over-alerting when used in a Swiss paediatric hospital. However, the current literature suggests that the severity rating of established contraindicated DDIs could be partially downgraded, and that patient/population-specific evaluations of DDI alerts are needed. PMID: 31422575 [PubMed - in process]
Source: Swiss Medical Weekly - August 11, 2019 Category: General Medicine Authors: Dieu LW, Leuppi-Taegtmeyer AB, van den Anker J, Trachsel D, Gotta V Tags: Swiss Med Wkly Source Type: research