Hidradenitis suppurativa: A practical review of possible medical treatments based on over 350 hidradenitis patients.

This article centers on medical therapies and will only passingly mention surgical and laser treatments. This article summarizes my treatment experience with over 350 HS patients. PMID: 24021361 [PubMed - in process]
Source: Dermatol Online J - Category: Dermatology Authors: Tags: Dermatol Online J Source Type: research

Related Links:

Authors: Ewy S, Pham H, Quan K, Su B, Tachdjian R Abstract Bullous pemphigoid (BP) is a rare blistering skin disease that is commonly treated with corticosteroids and immunosuppressive agents. Here, we present a 74-year-old woman with severe BP following a leg fracture who was successfully treated with omalizumab. We started her on a regimen of omalizumab 300 mg subcutaneously every 4 weeks, and within a week she reported significantly decreased pain and faster healing time of lesions. Incidentally, bilateral erythematous, non-blistering dermatitis developed 5 centimeters distal to the injection sites within a week...
Source: Journal of Drugs in Dermatology - Category: Dermatology Tags: J Drugs Dermatol Source Type: research
We present a patient with refractory neuropathic pain in a normotrophic spread-scar treated with the injection of BTA. A 47-year-old Caucasian female with a history of invasive melanoma of the left upper arm presented with pain in her excision scar, which she described as a “pins and needles” sensation alternating with a dull, deep ache. She had previously tried topical lidocaine, topical and intralesional steroids, and oral gabapentin without improvement. We treated the patient with 50 U of onabotulinumtoxinA intradermally at 1-1.5 cm intervals within and immediately around the perimeter of the scar. At 1-wee...
Source: Journal of Drugs in Dermatology - Category: Dermatology Tags: J Drugs Dermatol Source Type: research
Authors: Kircik LH Abstract Acne is primarily an inflammatory disease. Anti-inflammatory dose doxycycline (40mg: 30mg immediate release and 10mg delayed release beads) is approved for the treatment of rosacea but with demonstrated efficacy for acne. Fixed combination adapalene 0.3% and benzoyl peroxide 2.5% gel is a once-daily formulation approved for the topical management of acne vulgaris. It has both anti-inflammatory and anti-comedogenic properties. Options for management of severe acne are somewhat limited; many patients are not candidates for or refuse treatment with isotretinoin. Systemic antibiotics may be ...
Source: Journal of Drugs in Dermatology - Category: Dermatology Tags: J Drugs Dermatol Source Type: research
In this study, five of our previously synthesized NPs that showed excellent antimicrobial potential were compared for their in vivo toxicity and corresponding radical scavenging activities. Based on lowest morbidity, mortality, weight loss, toxicity and agglomeration profile, best NPs with highest antimicrobial potentials were screened out and used for further biomedical applications. The previously reported NPs used in this study included Aerva javanica synthesized nanoparticles (AjNPs), Heliotropium crispium synthesized nanoparticles (HcNPs), and violacein capped nanoparticles (VNPs), these showed least toxicity upon in ...
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
Authors: Swindell WR, Gau JT Abstract Pyoderma gangrenosum (PG) is a rare but serious neutrophilic dermatosis characterized by ulcerative lesions with violaceous borders. The disease mainly occurs in young or middle-aged adults. The authors present the case of a 79-year-old female nursing home patient who had an idiopathic PG-like ulcer on her lower extremity. Initial treatment with 3 courses of antibiotics and topical wound care for assumed cellulitis failed to improve the lesion, but the ulcer healed rapidly after a 1-week course of prednisone therapy (15 mg/d). This case provides insights into the challenges tha...
Source: Journal of the American Osteopathic Association - Category: Complementary Medicine Tags: J Am Osteopath Assoc Source Type: research
September 17, 2019 Chapel Hill, NCIn a step toward making high-quality health care available to more people around the world,IntraHealth International reached 341,445 health workers in 43 countries in 2018. These health workers are now making services available to more people in some of the most remote areas, destigmatizing procedures and services, and compiling meaningful and lifesaving data that allow for greater adaptability and long-term solutions.See more results in our full annual report.IntraHealth International reached 341,445 health workers in 43 countries in 2018.The World Health Organization and World Bank pro...
Source: IntraHealth International - Category: International Medicine & Public Health Authors: Tags: Family Planning & Reproductive Health HIV AIDS Infectious Diseases Maternal, Newborn, Child Health Digital Health Education Performance Health Workforce Systems Source Type: news
Despite the known benefits of weight loss for children and adolescents who are obese, some studies suggest that youth who diet may be at an increased risk of depression. Ameta-analysis published Monday inJAMA Pediatrics suggests obesity treatment in youth is not associated with an increased risk of depression or anxiety; rather, the analysis points to the mental health benefits of such programs for this population.“Structured and professionally run obesity treatment with a dietary component is associated with improvements in depression and anxiety for most participants,” wrote Hiba Jebeile, M.Nutr.Diet., of the...
Source: Psychiatr News - Category: Psychiatry Tags: depression diet Hiba Jebeile JAMA Pediatrics meta-analysis obesity weight loss Source Type: research
This study is registered with ClinicalTrials.gov, number NCT02400463, and is still recruiting.FindingsAs of Feb 7, 2019, five patients had been enrolled. The first patient was enrolled in February, 2016. No deaths were recorded, with a median follow-up of 490 days (IQR 190–1075). 2-month overall survival was 100% (95% CI 57–100). Regarding response, resolution of symptoms (either partial or complete) and disease-associated laboratory abnormalities was observed in all five patients. Cytopenias improved in all patients within the first week of treatment, leading to relatively rapid transfusion independence, disco...
Source: The Lancet Haematology - Category: Hematology Source Type: research
The testing and treatment of inmates for hepatitis C can be effective, but system efficiencies, perceptions, and limits on care after release can present obstacles.Medscape Medical News
Source: Medscape Hiv-Aids Headlines - Category: Infectious Diseases Tags: Gastroenterology News Source Type: news
Achalasia is a rare idiopathic condition defined by degeneration of ganglia in the esophageal myenteric plexus, leading to aperistalsis and failed relaxation of the lower esophageal sphincter.1 Progressive dysphagia and regurgitation often result in clinically significant weight loss and failure to thrive.2 Historically, achalasia was definitively treated with a laparoscopic Heller myotomy with or without concomitant partial fundoplication. More recently described, peroral endoscopic myotomy (POEM) is a minimally invasive, yet definitive, flexible endoscopic surgery, which mirrors the conventional laparoscopic surgical myo...
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Original article Source Type: research
More News: Absorica | Accutane | Acitretin | Aczone Gel | Avodart | Biaxin | Clarithromycin | Clindamycin | Colchicine | Colcrys | Corticosteroid Therapy | Dermatology | Enbrel | Fortamet | Hidradenitis | HIV AIDS | Hormones | Humira | Keloids | Men | Metformin | Methotrexate | Metronidazole | Minocycline | Prednisone | Propecia | Remicade | Restasis | Skin | Solodyn | Spironolactone | Weight Loss