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Total 43157 results found since Jan 2013.
Sclerosing angiomatoid nodular transformation of the spleen in a child with anemia: a case report and review of the literature
ConclusionAlthough sclerosing angiomatoid nodular transformation is exceedingly rare in children, it should be considered a differential diagnosis in pediatric splenic neoplasms with concurrent hematologic manifestations, such as anemia.
Source: Journal of Medical Case Reports - September 22, 2023 Category: General Medicine Source Type: research
News at a glance: Diphtheria vaccine shortage, prisoner release, and iNaturalist ’s growth
CONSERVATION
Popular biodiversity app to expand
The nonprofit that runs iNaturalist, a popular app and website for identifying species, has received a $10 million grant to expand. The funding from the Gordon and Betty Moore Foundation, announced last week, will allow iNaturalist—whose website is one of the largest generators of crowd-sourced species-occurrence data—to add users, technology, and observations to inform conservation. iNaturalist hopes to grow in nature-rich parts of the world, such as Asia and South America, which have fewer users uploading data. Since iNaturalist’s founding in 2008, the ...
Source: Science of Aging Knowledge Environment - September 21, 2023 Category: Geriatrics Source Type: research
News at a glance: Diphtheria treatment shortage, prisoner release, and iNaturalist ’s growth
CONSERVATION
Popular biodiversity app to expand
The nonprofit that runs iNaturalist, a popular app and website for identifying species, has received a $10 million grant to expand. The funding from the Gordon and Betty Moore Foundation, announced last week, will allow iNaturalist—whose website is one of the largest generators of crowd-sourced species-occurrence data—to add users, technology, and observations to inform conservation. iNaturalist hopes to grow in nature-rich parts of the world, such as Asia and South America, which have fewer users uploading data. Since iNaturalist’s founding in 2008, the ...
Source: ScienceNOW - September 21, 2023 Category: Science Source Type: news
Novel insight into the phenotype of microcephaly 19 in the patient with missense COPB2 mutation
This study describes a missense pathogenic homozygous variant (NM_004766.3:c.760 C > T, p.Arg254Cys) in the COPB2 gene, which was identified by Whole-Exome sequencing and confirmed by Sanger sequencing. The proband of the present study is an eight-and-a-half-year-old Iranian female who was born to consanguineous parents. She manifests global developmental delay, intellectual disability, microcephaly, seizures, spasticity, strabismus, and failure to thrive symptoms. Moreover, she is unable to stand, walk, or speak. Here we report the second homozygous mutation (NM_004766.3:c.760 C > T, p.Arg254Cys) in the COPB2 gene i...
Source: European Journal of Medical Genetics - September 21, 2023 Category: Genetics & Stem Cells Authors: Amirmasoud Shiri Hossein Jafari Khamirani Neda Kamal Jamal Manoochehri Mehdi Dianatpour Seyed Mohammad Bagher Tabei Seyed Alireza Dastgheib Source Type: research
A novel < em > METTL5 < /em > variant disrupting a donor splice site leads to primary microcephaly-related intellectual disability in an Iranian family: clinical features and literature review
In this study, due to the genetic heterogeneity of the disease, the whole-exome sequencing (WES) was performed on a 13-year-old boy suffering from microcephaly. In addition, Sanger sequencing, cosegregation analysis, and structural modelling were performed to identify and verify the causative variant in the proband and obligate carriers in the family. WES revealed a novel, homozygote 10-bp deletion in the donor splice site of 2nd exon of METTL5 gene (NM_014168:c.223_224?8del), which was found segregating with the phenotype in the pedigree. This variant meets the criteria of being pathogenic according to the American Colleg...
Source: Journal of Genetics - September 21, 2023 Category: Genetics & Stem Cells Authors: Fatemeh Shakarami Zahra Nouri Hossein Khanahmad Mohamadreza Ghazavi Mohammad Amin Tabatabaiefar Source Type: research
Quality of Life and Use of Complementary and Alternative Medicines among Narcotics Anonymous Patients: A Cross-Sectional Study in Southeast Iran
CONCLUSION: Although there was no difference in quality of life between CAM and non-CAM users, the present study showed that prayer and medicinal herbs were the most commonly used methods among narcotics anonymous patients. However, prayer and religious beliefs were successful in improving the quality of life of these individuals. Physicians and other healthcare providers must advise patients with addiction to use different CAMs in order to improve their quality of life and quit narcotics. Future in-depth studies could help these patients use CAMs and improve their quality of life.PMID:37727769 | PMC:PMC10506870 | DOI:10.1155/2023/3003247
Source: Evidence-based Complementary and Alternative Medicine - September 20, 2023 Category: Complementary Medicine Authors: Mahlagha Dehghan Hemn Kaka Mirza Sobhan Alaeifar Moazemeh Jazinizadeh Mohammad Hossein Iranmanesh Fateme Mohammadiakbarabadi Mina Salehi Asma Ghonchehpour Mohammad Ali Zakeri Source Type: research
Environmental Risk Factors for Pediatric Acute Leukemia: Methodology and Early Findings
Conclusions: The results of this study can be helpful in better understanding the environmental risk factors involved in the incidence of acute leukemia. Future publications based on the analysis of the database created in the present study can lead to recognizing these factors. In addition, evaluating the effect of these factors on treatment outcomes is an important step in reducing the burden of the disease.
Source: International Journal of Preventive Medicine - September 20, 2023 Category: International Medicine & Public Health Source Type: research
Central retinal vein and artery occlusion associated with sildenafil: a case report and review of the literature
ConclusionSildenafil may be associated with severe retinal vascular accidents in otherwise healthy young individuals.
Source: Journal of Medical Case Reports - September 20, 2023 Category: General Medicine Source Type: research
A large-scale study on the prevalence of intestinal parasites in patients referred to medical laboratories in Urmia, Northwest Iran
This study aimed to determine the prevalence of IPIs in pa...
Source: BMC Gastroenterology - September 20, 2023 Category: Gastroenterology Authors: Shiva Zeinali, Mahsa Rezgi, Morteza Gholinejad and Rasool Jafari Tags: Research Source Type: research
Global Bibliometric Analysis of Leishmaniasis Literature for the Last 20 Years and Investigating the Contribution of T ürkiye
CONCLUSION: The number of publications, especially in endemic areas, was found to be limited other than Brazil. Studies in this area should be supported to ensure the eradication of the disease.PMID:37724362 | DOI:10.4274/tpd.galenos.2023.76376
Source: Turkish Society for Parasitology - September 19, 2023 Category: Parasitology Authors: Sevil Alkan O ğuz Evlice Mustafa Serhat Şahinoğlu Source Type: research
Effect of interferon- α on COVID-19 in-hospital mortality: a large-scale propensity score-matched study
CONCLUSION: Our findings indicate that subcutaneous administration of IFN-α, with or without remdesivir, does not have any significant impact on COVID-19 mortality and ICU admission. Future clinical trials considering the time, subtype, and form of IFN-α administration are warranted to investigate the potential therapeutic effects of IFN-α on COVID-19.PMID:37724852 | DOI:10.1684/ecn.2023.0485
Source: Cancer Control - September 19, 2023 Category: Cancer & Oncology Authors: Mohamad Amin Pourhoseingholi Amirreza Rafiei Javazm Naghmeh Asadimanesh Fatemeh Shojaeian Mehdi Azizmohammad Looha Seyed Amir Ahmad Safavi-Naini Benyamin Mohammadzadeh Parnian Jamshidi Fatemeh Gholampoor Omid Yazdani Nadia Zameni Zahra Azizan Amirhossein Source Type: research
Training of Pelvic Floor Muscle Training Improves the Severity and Quality of Urine Incontinence and Increases Social Participation of Older Women in Southern Iran
CONCLUSIONS: Tele-training of the Kegel exercise, even during the pandemic, can play an important role in improving incontinence and social participation in older women. Therefore, this training can be used to prevent and improve urine incontinence in public health centers in the community.PMID:37723962 | DOI:10.2174/1874609816666230816125026
Source: Current Aging Science - September 19, 2023 Category: Geriatrics Authors: Somayeh SheikhHoseini Leila Ghahramani Fahimeh Khorasani Mahsa Yarelahi Abdolrahim Asadollahi Source Type: research
Global Bibliometric Analysis of Leishmaniasis Literature for the Last 20 Years and Investigating the Contribution of T ürkiye
CONCLUSION: The number of publications, especially in endemic areas, was found to be limited other than Brazil. Studies in this area should be supported to ensure the eradication of the disease.PMID:37724362 | DOI:10.4274/tpd.galenos.2023.76376
Source: Turkish Society for Parasitology - September 19, 2023 Category: Parasitology Authors: Sevil Alkan O ğuz Evlice Mustafa Serhat Şahinoğlu Source Type: research
A Review on the Antibiotic Resistance of < em > Shigella < /em > Strains in Iran
Infect Disord Drug Targets. 2023 Aug 31. doi: 10.2174/1871526523666230811093114. Online ahead of print.ABSTRACTShigella infection is commonly related to diarrhea and has been a noteworthy source of morbidity and mortality worldwide. There is a wide range of symptoms associated with these contagious microorganisms, from watery diarrhea to fulminant dysentery manifesting with recurrent bloody stools, fever, and prostration. While the mortality rate from Shigellosis has decreased significantly during the past three decades, it remains a principal cause of death in the world. The use of antibiotics in Shigella treatment remark...
Source: Infectious Disorders Drug Targets - September 19, 2023 Category: Infectious Diseases Authors: Mahdi Shooraj Marziye Taheri Mohammadmahdi Karimi-Yazdi Source Type: research
