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Total 98 results found since Jan 2013.

Innovation in drug development: applying human factors to understand asthmatic patients needs.
Conclusions: Findings from this study could help pharmaceutical industries to improve the development of their products and generate new innovative solutions and concepts to enhance the patients’ quality of life.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Lombardini, M., Marenghi, G., Bianchi, F. Tags: 05.01 - Airway pharmacology and treatment Source Type: research

Frequency of sensitizations and allergies to house dust mites
SummaryDomestic mites is the term used to describe dust mites and storage mites that prefer to live in houses and to which many people develop sensitization through the formation of specific IgE antibodies due to the high allergenic potency of mite allergens. As a  result, mites can trigger allergic diseases of the upper and lower respiratory tract as well as cross-reactions to other allergens. Sensitization to house mites is widespread in the German population. About 11 million adults are sensitized in Germany (15.9%). Men are more frequently affected than women, and sensitizations occur more frequently in large cities ...
Source: Allergo Journal International - November 7, 2022 Category: Allergy & Immunology Source Type: research

The Editors ’ Choice
Growing up on a farm is associated with a reduced prevalence of respiratory allergies in childhood. Whether this protective effect remains into adulthood is unknown. In this issue, Strieker et  al (p 1209) aimed to prospectively investigate the relationship between farm exposure and prevalence of allergic rhinitis and wheeze from childhood to early adulthood. The authors invited participants from phase 2 of the GABRIEL Study who were living in southern Germany (aged 6-11 years at baselin e and 20-25 years at follow-up) to complete a questionnaire on sociodemographic characteristics, farm contact, respiratory symptoms, and...
Source: Journal of Allergy and Clinical Immunology - November 1, 2022 Category: Allergy & Immunology Tags: The Editors ’ choice Source Type: research

For Kids with Long COVID, Good Treatment Is Hard to Find
Ayden Varno was outside doing chores one day in April 2021 when he felt an excruciating pain, like “a hot knife was being stabbed into my back multiple times,” he says. Ayden, who is now 13, spent most of the next eight months in pain so extreme he couldn’t walk unassisted, sleep through the night, or follow a full school curriculum. He also suffered frequent non-epileptic seizures related to his pain. Doctors near his home in Ohio had no idea why Ayden was in so much pain or what to do about it; some suggested he was having a psychotic episode or being abused at home, says his mother, Lynda Varno. The fa...
Source: TIME: Health - October 24, 2022 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized COVID-19 feature healthscienceclimate Source Type: news

IJERPH, Vol. 19, Pages 12530: Prevalence of Adverse Skin Reactions in Nursing Staff Due to Personal Protective Equipment during the COVID-19 Pandemic
ert Nienhaus In order to prevent the nosocomial transmission of the SARS-CoV-2 virus, it has become necessary for health workers to increase their use of personal protective equipment (PPE). The aim of the study was to investigate the prevalence and influencing factors for adverse skin reactions (ASR) due to occupational PPE use among nursing staff in Germany during the COVID-19 pandemic. The study uses a mixed methods design. A focus group was created with experts from the field of healthcare, and an online survey was then carried out among nursing staff. Influencing factors were identified using multivariate logistic...
Source: International Journal of Environmental Research and Public Health - October 1, 2022 Category: Environmental Health Authors: Claudia Westermann Nika Zielinski Christiane Altenburg Madeleine Dulon Olaf Kleinm üller Jan Felix Kersten Albert Nienhaus Tags: Article Source Type: research

Allergic to the world: can medicine help people with severe intolerance to chemicals?
Whether it ’s organic or psychosomatic or something in between, multiple chemical sensitivity can cause chronic illness, and its sufferers often feel abandonedSharon calls herself a universal reactor. In the 1990s, she became allergic to the world, to the mould colonising her home and the paint coating her kitchen walls, but also deodorants, soaps and anything containing plastic. Public spaces rife with artificial fragrances were unbearable. Scented disinfectants and air fresheners in hospitals made visiting doctors torture. The pervasiveness of perfumes and colognes barred her from in-person social gatherings. Even step...
Source: Guardian Unlimited Science - September 20, 2022 Category: Science Authors: Xi Chen Tags: Health & wellbeing Allergies Environment Air pollution Science Source Type: news

Munich atopy prediction study (MAPS): protocol for a prospective birth cohort addressing clinical and molecular risk factors for atopic dermatitis in early childhood
This study aims to comprehensively evaluate individual microbiome and immune responses in the context of environmental determinants related the risk of developing AD in the first 4 years of a child’s life. Methods and analyses The ‘Munich Atopic Prediction Study’ is a comprehensive clinical and biological investigation of a prospective birth cohort from Munich, Germany. Information on pregnancy, child development, environmental factors, parental exposures to potential allergens and acute or chronic diseases of children and parents are collected by questionnaires together with a meticulous clinical examin...
Source: BMJ Open - September 8, 2022 Category: General Medicine Authors: Preis, S., Schmidt, L., Tizek, L., Schielein, M., Lang, V., Bleuel, R., Duswald, A., Sitaru, S., Blasini, A., Gasteiger, C., Merdha, L., Kurgyis, Z., Kuschel, B., Hauenstein, E., Sander, M., Niedermeier, S., Argiriu, D., Engel, S., Skabytska, Y., Silva, R Tags: Open access, Dermatology Source Type: research

The prevalence of diseases in German emergency medical services staff: A survey study
This study indicates that the prevalence of obesity, depression, hypertension, and other disorders is high among study participants and disease prevention measures for pre-hospital EMS staff are needed.PMID:35129096 | DOI:10.1080/19338244.2022.2031846
Source: Archives of Environmental and Occupational Health - February 7, 2022 Category: Environmental Health Authors: Luis M öckel Christina Arnold Tobias May Thomas Hofmann Source Type: research

Using the Munich Oktoberfest to assess the prevalence and treatment of allergies
Allergies have an enormous socioeconomic impact since nearly 25% of the German population is affected. However, not all individuals with an allergy receive medical treatment. By using an unconventional setting, this study aimed to assess the prevalence and treatment of allergies in an unreferred population.
Source: Journal of Allergy and Clinical Immunology - February 1, 2022 Category: Allergy & Immunology Authors: Linda Tizek, Maximilian Schielein, Alexander Zink Source Type: research

White paper on peanut allergy: treatment pathway
ConclusionsAfter established diagnosis the standard of care is counseling to avoid peanut contact and prescription of emergency medications (oral antihistamines, oral steroids, inhaled β2-agonists, injectable intramuscular epinephrine) as needed. Instruction on the use of these emergency medications should be provided. A preparation for oral immunotherapy (OIT) for 4 to 17 years old peanut allergic children/ adolescents has been recently approved by the regulatory authorities. O IT for peanut allergy shows high efficacy and an acceptable safety profile, improves quality of life, and health economic aspects. Thus it offer...
Source: Allergo Journal International - December 6, 2021 Category: Allergy & Immunology Source Type: research

Late Breaking Abstract - Type 2 biomarker expression (FeNO and blood eosinophils) is higher in severe adult-onset than in severe early-onset asthma
Conclusion: Severe adult-onset asthma is characterised by a stronger type 2 phenotype than severe early-onset asthma, suggesting that the age of onset is a helpful clinical information for the identification of targeted treatments.
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Lommatzsch, M., Klein, M., Stoll, P., Virchow, J. C. Tags: Allergy and immunology Source Type: research

“Attention Everyone, Time Out!”: Safety Attitudes and Checklist Practices in Anesthesiology in Germany. A Cross-Sectional Study
Conclusions Our study paints a heterogeneous picture of the implementation, usage, and safety attitudes concerning the Safe Surgery Checklist as promoted by the WHO. The lack of standardized execution and team-mindedness can be taken as further evidence for the importance of interdisciplinary training focusing on human factors, communication, and collaboration rather than the mere implementation by decree.
Source: Journal of Patient Safety - August 26, 2021 Category: Health Management Tags: The Health Care Manager Source Type: research

Atopic diseases and airway-related symptoms in Bavarian pre-schoolers: determinants and association with immunization
ConclusionsThe present study is in line with the current state of research that MMR vaccination is not associated with atopic diseases.
Source: The European Journal of Public Health - August 26, 2021 Category: General Medicine Source Type: research

The Oxygen Saturation in the Retinal Vessels of Patients with Diabetes Mellitus - The Search for Determinants
CONCLUSION: The clinically observed improvement in the retinal state situation after intravitreal injections with VEGF inhibitors may be seen in association with the improved oxygen extraction. It seems reasonable to study whether a switch to sartans in the therapy of hypertension may improve retinal function.PMID:34000750 | DOI:10.1055/a-1384-0737
Source: Klinische Monatsblatter fur Augenheilkunde - May 17, 2021 Category: Opthalmology Authors: Richard Stodtmeister Vivien Mielke Dirk Sandner Source Type: research