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Specialty: Neurology
Condition: Disability
Infectious Disease: COVID-19

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Total 26 results found since Jan 2013.

Hospital Discharge and Readmissions Before and During the COVID-19 Pandemic for California Acute Stroke Inpatients
Stroke is a leading cause of death and disability in the United States, with approximately 795,000 new strokes occurring annually, including acute ischemic stroke (AIS), intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH).1 The Coronavirus Disease 2019 (COVID-19) pandemic has impacted all levels of care for stroke patients, such as delays in initial presentation, reduction in acute therapies, limitations of in-patient resources, delays or lack of initiation of secondary stroke prevention therapy, and limitations in rehabilitation services after hospital discharge.
Source: Journal of Stroke and Cerebrovascular Diseases - June 23, 2023 Category: Neurology Authors: George P. Albert, Daryl C. McHugh, Debra E. Roberts, Adam G. Kelly, Remi Okwechime, Robert G. Holloway, Benjamin P. George Source Type: research

DIA-based technology explores hub pathways and biomarkers of neurological recovery in ischemic stroke after rehabilitation
ConclusionComplement-related pathways, lipoprotein-related functions and effects, thrombosis and hemostasis, coronavirus disease (COVID-19), and inflammation and immunity pathways are not only key pathways in the pathogenesis of ischemic stroke but also the main pathways of action of rehabilitation therapy. In addition, IGHA1, LRG1, IGHV3-64D, and CP are upregulated in patients with ischemic stroke and downregulated after rehabilitation, which may be used as biomarkers to monitor neurological impairment and recovery after stroke.
Source: Frontiers in Neurology - March 7, 2023 Category: Neurology Source Type: research

Psychological impact of COVID-19 containment on CADASIL patients
ConclusionPsychological impact of the containment was limited in CADASIL patients and did not appear related to the disease status. About 9% of patients presented with significant posttraumatic and stressor-related disorder manifestations which were predicted by living alone, unemployment, or exhaustion related to parental burden.
Source: Journal of Neurology - March 4, 2023 Category: Neurology Source Type: research

Treatments in Ischemic Stroke: Current and Future
Background and Aim: Despite progress made over the last 30 years, stroke is still a leading cause of disability and mortality; likewise, its burden is expected to increase over the next decades, due to population growth and aging. The development of drugs with better safety-efficacy profiles as well as strategies able to improve ischemic stroke management from the pre-hospital setting is needed.Summary: The pathophysiology of ischemic stroke involves multiple pathways resulting in cerebral artery obstruction and brain tissue ischemia. To date, the only approved drug for acute ischemic stroke is intravenous thrombolytic alt...
Source: European Neurology - August 2, 2022 Category: Neurology Source Type: research

Therapeutic Approaches to the Neurologic Manifestations of COVID-19
AbstractAs of May 2022, there have been more than 527 million infections with severe acute respiratory disease coronavirus type 2 (SARS-CoV-2) and over 6.2 million deaths from Coronavirus Disease 2019 (COVID-19) worldwide. COVID-19 is a multisystem illness with important neurologic consequences that impact long-term morbidity and mortality. In the acutely ill, the neurologic manifestations of COVID-19 can include distressing but relatively benign symptoms such as headache, myalgias, and anosmia; however, entities such as encephalopathy, stroke, seizures, encephalitis, and Guillain –Barre Syndrome can cause neurologic inj...
Source: Neurotherapeutics - July 21, 2022 Category: Neurology Source Type: research

Comparison of disease profiles and three-month outcomes of patients with neurological disorders with and without COVID-19: An ambispective cohort study
Conclusion: Patients with neurological disorders presenting with COVID-19 infection had worse outcomes, including in-hospital and 3 months disability.
Source: Annals of Indian Academy of Neurology - May 25, 2022 Category: Neurology Authors: Kanchana S Pillai Deepti Vibha Pranjal Gupta Pachipala Sudheer Biswamohan Mishra Rahul S Oinam Ayush Mohan Kamalesh Tayade Padma Srivastava Manjari Tripathi Achal K Srivastava Rohit Bhatia Roopa Rajan Awadh K Pandit Rajesh K Singh Arunmozhimaran Elavarasi Source Type: research

Neuroimmune disorders in COVID-19
AbstractSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the aetiologic agent of the coronavirus disease 2019 (COVID-19), is now rapidly disseminating throughout the world with 147,443,848 cases reported so far. Around 30 –80% of cases (depending on COVID-19 severity) are reported to have neurological manifestations including anosmia, stroke, and encephalopathy. In addition, some patients have recognised autoimmune neurological disorders, including both central (limbic and brainstem encephalitis, acute disseminated encephalomyelitis [ADEM], and myelitis) and peripheral diseases (Guillain–Barré and Miller ...
Source: Journal of Neurology - May 20, 2022 Category: Neurology Source Type: research

Grace Under Pressure: Resiliency of Quality Monitoring of Stroke Care During the Covid-19 Pandemic in Mexico City
Stroke is one of the leading causes of death and disability among adults worldwide. The World Health Organization (WHO) officially declared a COVID-19 pandemic on March 11, 2020. The first case in Mexico was confirmed in February 2020, subsequently becoming one of the countries most affected by the pandemic. In 2020, The National Institute of Neurology of Mexico started a Quality assurance program for stroke care, consisting of registering, monitoring and feedback of stroke quality measures through the RES-Q platform. We aim to describe changes in the demand for stroke healthcare assistance at the National Institute of Neu...
Source: Frontiers in Neurology - April 6, 2022 Category: Neurology Source Type: research

Impact of the COVID-19 pandemic on the frequency, clinical spectrum and outcomes of pediatric guillain-Barr & #233; syndrome in India: A multicentric ambispective cohort study
Conclusions: The COVID-19 pandemic led to a marked decline in pediatric GBS presenting to hospitals. Antecedent illnesses, clinical and electrophysiological profile of GBS remained largely unchanged from the pre-pandemic era.
Source: Annals of Indian Academy of Neurology - February 22, 2022 Category: Neurology Authors: Divyani Garg Rajinder K Dhamija Aditya Choudhary Ritu Shree Sujit Kumar Priyanka Samal Abhishek Pathak Pamidimukkala Vijaya Yareeda Sireesha Sruthi S Nair Sanjay Sharma Soaham Desai Human P Sinha Ayush Agarwal Ashish Upadhyay MV Padma Srivastava Rohit Bha Source Type: research

Stroke Hospital Admissions during the COVID-19 Outbreak in S ão Paulo, Brazil
Conclusion: We argue for policies aimed at improving stroke care and developing awareness campaigns regarding the importance of early diagnosis and treatment, as even in less severe presentations, stroke can trigger an increase in mortality, cost, and long-term disability.Cerebrovasc Dis
Source: Cerebrovascular Diseases - February 17, 2022 Category: Neurology Source Type: research

Feasibility of a remotely supervised home-based group eHealth Fitness and Mobility Exercise program for stroke: French-Canadian version preliminary study
CONCLUSION: FAME@home was feasible to deliver as a remotely supervised group exercise program to community-dwelling stroke survivors, with high levels of retention and adherence. FAME@home improved accessibility to exercise and facilitated engagement by having a class schedule and social interaction.PMID:34994303 | DOI:10.1080/10749357.2021.2012008
Source: Topics in Stroke Rehabilitation - January 7, 2022 Category: Neurology Authors: Marie-Andr e Gagnon Charles S biyo Batcho Marie-Louise Bird Benoit Labb Krista L Best Source Type: research

The impact of coronavirus disease 2019 on emotional and behavioral stress of informal family caregivers of individuals with stroke or traumatic brain injury at chronic phase living in a Mediterranean setting
ConclusionsOur results suggest specific items in which informal caregivers could be supported considering cause or severity of the recipients of care.
Source: Brain and Behavior - December 15, 2021 Category: Neurology Authors: Alejandro Garcia ‐Rudolph, Joan Sauri, Alberto Garcia‐Molina, Blanca Cegarra, Eloy Opisso, Josep Maria Tormos, Dietmar Frey, Vince Istvan Madai, Montserrat Bernabeu Tags: ORIGINAL ARTICLE Source Type: research