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Does Metformin combined with Clomiphene Citrate improve fertility related outcomes in Clomiphene resistant women with PCOS: A systematic review
Publication date: June 2014 Source:Middle East Fertility Society Journal, Volume 19, Issue 2 Author(s): Sabraj Gill , Ailsa Gemmell , Rebecca Colleran , Nurhazwani Bt Zanuri , Helen O’Brien , Amudha Poobalan Background Polycystic Ovary Syndrome (PCOS) is clinically associated with infertility. Many women are resistant to Clomiphene Citrate and the addition of insulin sensitisers may help to overcome this challenge. Objective This review aims to assess if Metformin added to Clomiphene Citrate improves pregnancy outcomes in patients with PCOS and are resistant to Clomiphene Citrate. Search strategy A systematic search ...
Source: Middle East Fertility Society Journal - November 3, 2014 Category: Reproduction Medicine Source Type: research

A pilot study to search possible mechanisms of ultralong gonadotropin-releasing hormone agonist therapy in IVF-ET patients with endometriosis
Conclusions: Ultralong GnRHa therapy reduces the detrimental effects of cytotoxic cytokines and oxidative stress in the ovary in patients with endometriosis.
Source: Journal of Ovarian Research - October 21, 2014 Category: Cancer & Oncology Authors: Hiroshi TamuraAkihisa TakasakiYasuhiko NakamuraFumitaka NumaNorihiro Sugino Source Type: research

Title: In Search of “Just Right”: The Challenge of Regulating Arsenic in Rice
Charles W. Schmidt, MS, an award-winning science writer from Portland, ME, has written for Discover Magazine, Science, and Nature Medicine. Background image: © Koji Kitagawa/amanaimages/Corbis About This Article open Citation: Schmidt CW. 2015. In search of “just right”: the challenge of regulating arsenic in rice. Environ Health Perspect 123:A16–A19; http://dx.doi.org/10.1289/ehp.123-A16 News Topics: Agriculture and Farming, Arsenic, Diet and Nutrition, Drinking Water Quality, Food Safety and Regulation, Laws, Regulations, and Policy, Risk Assessment, Soil Pollution, Standards Published: 1 January 2015 PDF Ver...
Source: EHP Research - December 31, 2014 Category: Environmental Health Authors: Web Admin Tags: Featured News Spheres of Influence Agriculture and Farming Arsenic Diet and Nutrition Drinking Water Quality Food Safety and Regulation Risk Assessment Soil Pollution Standards Source Type: research

WITHDRAWN: Recombinant FSH versus urinary gonadotrophins or recombinant FSH for ovulation induction in subfertility associated with polycystic ovary syndrome.
CONCLUSIONS: Further research on these gonadotrophin comparisons is unlikely to identify substantive differences in effectiveness or safety. Adherence to familiar treatment protocols and adherence to cancellation criteria is important. PMID: 26299778 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - August 24, 2015 Category: Journals (General) Authors: Nahuis M, Bayram N, Van der Veen F, van Wely M Tags: Cochrane Database Syst Rev Source Type: research

Antenatal care for healthy pregnant women: a mapping of interventions from existing guidelines to inform the development of new WHO guidance on antenatal care.
CONCLUSION: Mapping the current guidelines including practices related to routine ANC informed the scoping phase for the WHO guideline for ANC. Our analysis indicates that guideline development processes may lead to different recommendations, due to context, evidence base or assessment of evidence. It would be useful for guideline developers to map and refer to other similar guidelines and, where relevant, explore the discrepancies in recommendations and others. TWEETABLE ABSTRACT: We identified existing ANC guidelines and mapped scope, practices, recommendations and source of evidence. PMID: 26694196 [PubMed - a...
Source: BJOG : An International Journal of Obstetrics and Gynaecology - December 23, 2015 Category: OBGYN Authors: Abalos E, Chamillard M, Diaz V, Tuncalp Ӧ, Gülmezoglu AM Tags: BJOG Source Type: research

The Human Cost of Tobacco Chewing Among Pregnant Women in India: A Systematic Review and Meta-analysis
Conclusion There was a suggestive evidence of SLT use associated with adverse pregnancy outcomes among women in India. Further studies in this field are required to generate more conclusive evidence.
Source: The Journal of Obstetrics and Gynecology of India - January 7, 2016 Category: OBGYN Source Type: research

Obstetric and neonatal complications in pregnancies conceived after oocyte donation - a systematic review and meta-analysis.
CONCLUSIONS: OD conceptions are associated with adverse obstetric and neonatal outcomes. To avoid the additional increase in risk from multiplicity, single-embryo transfer should be the choice of option in OD cycles. TWEETABLE ABSTRACT: Oocyte donation pregnancies have increased risk of a range of obstetric and neonatal complications. PMID: 27592694 [PubMed - as supplied by publisher]
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 4, 2016 Category: OBGYN Authors: Storgaard M, Loft A, Bergh C, Wennerholm UB, Söderström-Anttila V, Romundstad LB, Aittomaki K, Oldereid N, Forman J, Pinborg A Tags: BJOG Source Type: research

$3.6 million boost in search for new malaria drugs
(Walter and Eliza Hall Institute) A $US3.6 million grant from global charity the Wellcome Trust will accelerate the search for much-needed new medicines for malaria, a disease that kills almost half a million people worldwide each year, especially young children and pregnant women.The funding grant will support a collaborative team of researchers from Australia's Walter and Eliza Hall Institute and biopharmaceutical company Merck& Co., Inc., Kenilworth, N.J., USA, known as MSD in Australia, to identify and investigate 'drug-like' molecules for treating malaria.
Source: EurekAlert! - Medicine and Health - May 1, 2018 Category: International Medicine & Public Health Source Type: news

Primary and secondary prevention of preterm birth: a review of systematic reviews and ongoing randomized controlled trials
ConclusionThe overview serves as a guide to current evidence relevant to PTB prevention. Only a few interventions have been demononstrated to be effective, including cerclage, progesterone, low dose aspirin, and lifestyle and behavioural changes. For several of the interventions evaluated, there was insufficient evidence to assess whether they were effective or not.
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - February 14, 2019 Category: OBGYN Source Type: research

In Search of Congenital Chagas Disease in the Sierra Nevada de Santa Marta, Colombia.
Abstract Chagas disease remains a major impediment to sustainable socioeconomic development in Latin America. Transplacental transmission explains the persistence of transmission in urban areas, in non-endemic regions, and in areas with an established interrupted vectorial transmission. One of every five cases of congenital Chagas disease in the world occurs in Colombia and Venezuela. The massive migration of impoverished populations from neighboring Venezuela has worsened the situation creating a humanitarian crisis in Northeastern Colombia, including the Sierra Nevada de Santa Marta. The prevalence of Chagas inf...
Source: The American Journal of Tropical Medicine and Hygiene - June 30, 2019 Category: Tropical Medicine Authors: Parra-Henao G, Oliveros H, Hotez PJ, Motoa G, Franco-Paredes C, Henao-Martínez AF Tags: Am J Trop Med Hyg Source Type: research

Opportunities for improving hypertensive disorders of pregnancy (HDP) management in primary care settings: a review of international published guidelines in the context of pregnancy care in Indonesia
Publication date: Available online 22 January 2020Source: Pregnancy HypertensionAuthor(s): Fitriana Murriya Ekawati, Ova Emilia, Shaun Brennecke, Jane Gunn, Sharon Licqurish, Phyllis LauAbstractGlobally, almost maternal mortality caused by HDP occurs in low to middle-income countries (LMIC); yet, limited guidance is available to local primary care practitioners who are usually the main health care providers. This review examined existing international practice guidelines to identify potential practices to improve HDP management in Indonesian primary care. We performed a structured literature search strategies and snowballi...
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - January 22, 2020 Category: OBGYN Source Type: research

The effect of paternal exposure to immunosuppressive drugs on sexual function, reproductive hormones, fertility, pregnancy and offspring outcomes: a systematic review
AbstractBACKGROUNDInformation regarding the possible influence of immunosuppressive drugs on male sexual function and reproductive outcomes is scarce. Men diagnosed with immune-mediated diseases and a wish to become a father represent an important neglected population since they lack vital information to make balanced decisions about their treatment.OBJECTIVE AND RATIONALEThe aim of this research was to systematically review the literature for the influence of paternal immunosuppressive drug use on many aspects of male sexual health, such as sexual function, fertility, pregnancy outcomes and offspring health outcomes.SEARC...
Source: Human Reproduction Update - August 3, 2020 Category: OBGYN Source Type: research

Operation Food Search expands study of food for health benefits
Operation Food Search, a St. Louis-based nonprofit hunger relief organization, has begun a three-year study to demonstrate the economic and health benefits of providing healthy food to pregnant women. The organization began a two-year pilot of the program, Fresh Rx: Nourishing Healthy Starts, in late 2018 to eliminate food insecurity, and other social determinants of health, during pregnancy and postpartum in low-income women, as well as improve birth outcomes for mothers and babies. The prog ram…
Source: bizjournals.com Health Care:Pharmaceuticals headlines - November 25, 2020 Category: Pharmaceuticals Authors: Diana Barr Source Type: news

Cost-effectiveness evidence for strategies to promote or support breastfeeding: a systematic search and narrative literature review
Global health policy recommends exclusive breastfeeding until infants are 6  months. Little is known about the cost-effectiveness of breastfeeding promotion strategies. This paper presents a systematic search a...
Source: BMC Pregnancy and Childbirth - December 3, 2020 Category: OBGYN Authors: Elizabeth M. Camacho and Hannah Hussain Tags: Research article Source Type: research