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Total 703 results found since Jan 2013.

Stroke after Pregnancy Disorders
Women with hypertensive pregnancy disorders are at risk of developing stroke, possibly mediated by female-specific risk factors. Pregnancy is considered to be a stress test for cardiovascular health later in life [1]. In the current study we assessed the occurrence of pregnancy disorders, among women with a history of ischemic stroke who participated in the Dutch acute stroke study (DUST) and related these risk factors to age of stroke onset, stroke subtype, radiological characteristics and clinical outcome.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - June 9, 2017 Category: OBGYN Authors: Gerbrand A. Zoet, Katie M. Linstra, Marie Louise E. Bernsen, Maria P.H. Koster, Irene C. van der Schaaf, L. Jaap Kappelle, Bas B. van Rijn, Arie Franx, Marieke J.H. Wermer, Birgitta K. Velthuis, on behalf of the DUST investigators Tags: Letter to the Editor Source Type: research

Comparison of Clevidipine and Nicardipine for Acute Blood Pressure Reduction in Hemorrhagic Stroke
ConclusionsIn patients with hemorrhagic stroke, nicardipine appeared to have similar efficacy as clevidipine in SBP reduction, with a more likely reduction of rebound hypertension and drug cost. This retrospective study was underpowered, which may limit these implications. Further prospective studies are warranted to confirm these results.
Source: Neurocritical Care - December 13, 2021 Category: Neurology Source Type: research

Risk of future stroke increased by hypertension during pregnancy
High blood pressure during pregnancy could dramatically raise a woman's lifetime risk of stroke, according to a study presented at the Canadian Stroke Congress. "We've found that women who had high blood pressure during pregnancy could be at higher risk of stroke, particularly if they had pre-eclampsia, which is a more severe form of high blood pressure," says Dr. Aravind Ganesh, a neurology resident at the University of Calgary. "The elevated risk of stroke could be as high as 40 per cent." Dr. Ganesh, along with Neha Sarna (medical student), Dr...
Source: Health News from Medical News Today - October 22, 2013 Category: Consumer Health News Tags: Hypertension Source Type: news

The risk of fatal stroke in Finnish postmenopausal hormone therapy users before and after the Women's Health Initiative: A cohort study
Stroke is the third most common cause of death and the most common cause of prolonged disability in women worldwide[1]. Therefore, the American Heart and Stroke Association recently published strict new guidelines for the prevention of stroke in women [2]. These guidelines acknowledge a number of female gender-related risk factors for stroke, such as migraine, pregnancy, pre-eclampsia, atrial fibrillation, obesity, metabolic syndrome, living alone -status and consequent delay in thrombolysis, and longevity.
Source: Maturitas - April 13, 2015 Category: Primary Care Authors: Pauliina Tuomikoski, Heli Lyytinen, Pasi Korhonen, Fabian Hoti, Pia Vattulainen, Mika Gissler, Olavi Ylikorkala, Tomi S. Mikkola Source Type: research

Maternal hypertension programs increased cerebral tissue damage following stroke in adult offspring.
Abstract The maternal system is challenged with many physiological changes throughout pregnancy to prepare the body to meet the metabolic needs of the fetus and for delivery. Many pregnancies, however, are faced with pathological stressors or complications that significantly impact maternal health. A shift in this paradigm is now beginning to investigate the implication of pregnancy complications on the fetus and their continued influence on offspring disease risk into adulthood. In this investigation, we sought to determine whether maternal hypertension during pregnancy alters the cerebral response of adult offsp...
Source: Molecular and Cellular Biochemistry - July 14, 2015 Category: Biochemistry Authors: Ventura NM, Jin AY, Tse MY, Peterson NT, Andrew RD, Mewburn JD, Pang SC Tags: Mol Cell Biochem Source Type: research

Acute ischemic stroke and abnormal blood hemoglobin concentration
ConclusionsOur results suggest that an elevated HGB on the initial admission is associated with more severe strokes, greater disability at discharge, and higher 30‐day mortality after AIS. A low HGB on admission is associated with longer stay in the acute care hospital.
Source: Acta Neurologica Scandinavica - October 21, 2015 Category: Neurology Authors: J. C. Furlan, J. Fang, F. L. Silver Tags: Original Article Source Type: research

The Impact of Pregnancy on Hemorrhagic Stroke in Young Women
Conclusions: Women with pregnancy-associated HS had fewer cerebrovascular risk factors, lower odds of having ­underlying vascular lesions, and higher proportion of ­migraine and RCVS compared with similar-aged non-­pregnant women. Pregnancy-associated HS appears to represent a unique pathophysiological process, requiring targeted study.Cerebrovasc Dis 2018;46:10 –15
Source: Cerebrovascular Diseases - July 6, 2018 Category: Neurology Source Type: research

Impact of hypertensive disorders of pregnancy on short- and long-term outcomes of pregnancy-associated hemorrhagic stroke
ConclusionsIn this retrospective study, women with hypertension disorders of pregnancy did not show worse short-term outcomes of pregnancy-associated hemorrhagic stroke compared to those without but had poorer long-term functional outcomes. This underlines the importance of prevention, recognition, and treatment of hypertension disorders in these women.
Source: Frontiers in Neurology - March 16, 2023 Category: Neurology Source Type: research

High blood pressure during pregnancy could elevate the risk of a future stroke
(Heart and Stroke Foundation of Canada) High blood pressure during pregnancy could dramatically raise a woman's lifetime risk of stroke, according to a study presented today at the Canadian Stroke Congress.
Source: EurekAlert! - Medicine and Health - October 18, 2013 Category: Global & Universal Source Type: news

Relaxin peptide hormones are protective during the early stages of ischemic stroke in male rats.
Abstract The pregnancy hormone relaxin protects tissue from ischemic damage. The ability of relaxin-3, a relaxin paralog, to do so has not been explored. The cerebral expression of these peptides and their receptors make them logical targets for study in the ischemic brain. We assessed relaxin peptide-mediated protection, relative relaxin family peptide receptor (RXFP) involvement and protective mechanisms. Sprague-Dawley rats receiving permanent or transient middle cerebral artery occlusions (pMCAO and tMCAO, respectively), were treated with relaxin peptides and brains collected for infarct analysis. Activation o...
Source: Endocrinology - December 2, 2014 Category: Endocrinology Authors: Bergeron LH, Willcox JM, Alibhai FJ, Connell BJ, Saleh TM, Wilson BC, Summerlee AJ Tags: Endocrinology Source Type: research

Correlation of plasma soluble cluster of differentiation 40 ligand, alpha fetoprotein A, and pregnancy-associated plasma protein A with carotid plaque in patients with ischemic stroke.
This study investigated the correlation of plama levels of inflammatory biomarkers [soluble cluster of differentiation 40 ligand (sCD40L), alpha fetoprotein A (fetuin-A), and pregnancy-associated protein A (PAPP-A)] with carotid plaque in patients with acute ischemic stroke. After undergoing color Doppler ultrasonography of the bilateral carotid arteries, 200 patients with acute ischemic stroke were grouped into plaque and non-plaque groups. The plaque group was further divided into stable and unstable plaque sub-groups by carotid plaque stability. Inter-group and -subgroup comparisons included demographic characteristics,...
Source: Genetics and Molecular Research - July 29, 2015 Category: Genetics & Stem Cells Authors: Wang YJ, Gong ZQ, Bi XM, Li YL Tags: Genet Mol Res Source Type: research

Antiphospholipid Syndrome-Associated Crescendo Stroke Events Treated with Rituximab (P4.351)
Discussion APS is an autoimmune condition associated with persistent antiphospholipid antibodies, characterised by thrombosis and pregnancy morbidity [1].Regarding APS and stroke the optimal antithrombotic agent, intensity of anticoagulation, and duration of treatment remains controversial[2]. Analysis of the APASS subgroup in the WARS study found aspirin and warfarin to be equally effective agents for secondary stroke prevention [2]. The majority of panel members at the International Congress on Antiphospholipid Antibodies recommended warfarin or combination aspirin and warfarin for patients with definite APS and arterial...
Source: Neurology - April 3, 2016 Category: Neurology Authors: O' Connor, A., Murphy, G., Cronin, S. Tags: Cerebrovascular Case Reports Source Type: research

Low-dose second-generation oral contraceptives are associated with the lowest increased risk of cardiovascular adverse effects
Commentary on: Weill A, Dalichampt M, Raguideau F, et al.. Low dose oestrogen combined oral contraception and risk of pulmonary embolism, stroke, and myocardial infarction in five million French women: cohort study. BMJ 2016;353:i2002 . Context Oral contraceptives (OCs) are associated with an increased risk of cardiovascular disease. The association varies depending on whether the cardiovascular disease is arterial or venous and with varying progestogens and dosages of the oestrogen compound ethinyloestradiol. A recent Cochrane review concluded that OCs with the progestogens gestodene, desogestrel, cyproterone acetate or d...
Source: Evidence-Based Medicine - November 22, 2016 Category: Internal Medicine Authors: Lokkegaard, E. Tags: Health policy, Epidemiologic studies, Drugs: cardiovascular system, Stroke, Hypertension, Contraception, Drugs: obstetrics and gynaecology, Pregnancy, Ischaemic heart disease, Venous thromboembolism, Pulmonary embolism Aetiology/Harm Source Type: research

Risk Factors for Pregnancy-Associated Stroke in Women with Preeclampsia: a Case-Control Study (S15.007)
Conclusions:Chronic hypertension, underlying prothrombotic conditions and infections increase PAS risk in women with PEC. These women may warrant closer postpartum monitoring, due to high PAS-associated mortality in this population.Disclosure: Dr. Miller has nothing to disclose. Dr. Gatollari has nothing to disclose. Dr. Too has nothing to disclose. Dr. Boehme has nothing to disclose. Dr. Leffert has nothing to disclose. Dr. Elkind has received personal compensation in an editorial capacity for Neurology. Dr. Willey has received personal compensation for activities with Heartware Incoporated as a consultant, from Claret Me...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Miller, E., Gatollari, H., Too, G., Boehme, A., Leffert, L., Elkind, M., Willey, J. Tags: Neuroepidemiology Source Type: research

Alteplase Therapy for Acute Ischemic Stroke in Pregnancy: Two Case Reports and a Systematic Review of the Literature
This article is protected by copyright. All rights reserved.
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - May 10, 2019 Category: Drugs & Pharmacology Authors: Klayton M. Ryman, Wilson D. Pace, Shawn Smith, Gabriel V. Fontaine Tags: Review of Therapeutics Source Type: research