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Condition: Atrial Fibrillation
Procedure: Heart Valve Surgery

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Total 444 results found since Jan 2013.

Oral anti-Xa anticoagulation after Trans-Aortic Valve Implantation for Aortic Stenosis: The randomized ATLANTIS trial
Conclusions ATLANTIS tests the superiority of an apixaban-based strategy versus the recommended standard of care strategy to reduce the risk of post-TAVR thromboembolic and bleeding complications in an all comer population.
Source: American Heart Journal - March 10, 2018 Category: Cardiology Source Type: research

EdoxabaN Versus standard of care and theIr effectS on clinical outcomes in pAtients havinG undergonE Transcatheter Aortic Valve Implantation in Atrial Fibrillation—Rationale and design of the ENVISAGE-TAVI AF trial
Publication date: November 2018Source: American Heart Journal, Volume 205Author(s): Nicolas M. Van Mieghem, Martin Unverdorben, Marco Valgimigli, Roxana Mehran, Eric Boersma, Usman Baber, Christian Hengstenberg, Minggao Shi, Cathy Chen, Shigeru Saito, Roland Veltkamp, Pascal Vranckx, George D. DangasTranscatheter aortic valve implantation, also called transcatheter aortic valve replacement (TAVR), is the treatment of choice for patients with severe aortic stenosis and intermediate to high operative risk. A significant portion of TAVR patients have atrial fibrillation (AF) requiring chronic oral anticoagulation. In moderate...
Source: American Heart Journal - August 30, 2018 Category: Cardiology Source Type: research

Minimally Invasive Approaches to Surgical Aortic Valve Replacement: A Meta-Analysis
ConclusionsMinimally invasive approaches to AVR yield excellent outcomes in high volume centers. They reduce hospital stay and incidence of post-operative atrial fibrillation, and, therefore, should be considered in patients undergoing AVR. However, the operative approach should be selected according to surgeon’s technical expertise and what is best for specific patient profile.
Source: The Annals of Thoracic Surgery - September 6, 2018 Category: Cardiovascular & Thoracic Surgery Source Type: research

Minimally Invasive Approaches to Surgical Aortic Valve Replacement: A Meta-Analysis.
CONCLUSIONS: Minimally invasive approaches to AVR yield excellent outcomes in high volume centers. They reduce hospital stay and incidence of post-operative atrial fibrillation, and, therefore, should be considered in patients undergoing AVR. However, the operative approach should be selected according to surgeon's technical expertise and what is best for specific patient profile. PMID: 30189193 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - September 3, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Chang C, Raza S, Altarabsheh SE, Delozier S, Sharma UM, Zia A, Neudecker M, Markowitz AH, Sabik JF, Deo SV Tags: Ann Thorac Surg Source Type: research

Mechanical Versus Bioprosthetic Aortic Valve Replacement in Patients Aged 50 Years and Younger
ConclusionsThe increased risk of reoperation for bAVR and major bleeding incidents for mAVR was not reflected in midterm and long-term survival differences between the two groups. Our results suggest that bAVR may be an acceptable prosthesis choice for some patients aged 50 years and younger, although the results should be taken with caution.Visual Abstract
Source: The Annals of Thoracic Surgery - September 21, 2018 Category: Cardiovascular & Thoracic Surgery Source Type: research

Preventable Cases of Oral Anticoagulant-Induced Bleeding: Data From the Spontaneous Reporting System
Conclusion: Our findings describe the most reported risk factors for preventability of oral anticoagulant-induced bleedings. These factors may be useful for targeting interventions to improve pharmacovigilance activities in our regional territory and to reduce the burden of medication errors and inappropriate prescription. Introduction Oral anticoagulant therapy is widely used for the prevention of stroke and systemic embolism in patients with atrial fibrillation, or for the prevention and treatment of deep vein thrombosis and pulmonary embolism (Raj et al., 1994; Monaco et al., 2017). Oral anticoagulants can be di...
Source: Frontiers in Pharmacology - April 29, 2019 Category: Drugs & Pharmacology Source Type: research

Transcatheter versus surgical aortic valve replacement in low and intermediate risk patients with severe aortic stenosis: systematic review and meta-analysis of randomized controlled trials and propensity score matching observational studies.
Conclusions: TAVR is comparable to SAVR in terms of mortality and disabling stroke in severe AS patients at low and intermediate risk, but higher proportion of AV re-intervention observed in TAVR. Those results should encourage caution when extending the indications of TAVR into low risk patients, especially for young low risk patients. Systematic review registration: PROSPERO CRD 42018112626. PMID: 31285888 [PubMed]
Source: Journal of Thoracic Disease - July 10, 2019 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Incidence, 30-day readmission rates and predictors of readmission after new onset atrial fibrillation who underwent transcatheter aortic valve replacement
ConclusionsIncidence of NOAF is associated with increased risk of readmissions and ischemic stroke. Future research should focus on interventions to prevent avoidable readmissions and associated morbidity and mortality.
Source: Heart and Lung: The Journal of Acute and Critical Care - November 3, 2019 Category: Respiratory Medicine Source Type: research

Mid-term single-centre outcomes of BioIntegral compared to Freestyle aortic conduit implantation.
CONCLUSIONS: FS and BI provide comparable clinical midterm results and hemodynamic parameters. Simplified implantation technique providing shorter cardiopulmonary bypass and operation times are advantageous for BI. PMID: 31815376 [PubMed - as supplied by publisher]
Source: The Journal of Cardiovascular Surgery - December 5, 2019 Category: Cardiovascular & Thoracic Surgery Authors: Mehdiani A, Sorokin VA, Sule J, Smiris K, Stadnik D, Lichtenberg A, Blehm A Tags: J Cardiovasc Surg (Torino) Source Type: research

Concomitant atrial fibrillation ablation in patients undergoing coronary artery bypass and cardiac valve surgery
This article is protected by copyright. All rights reserved.
Source: Journal of Cardiovascular Electrophysiology - February 28, 2020 Category: Cardiology Authors: Andrei Churyla, Anand Desai, Kruse Jane, James Cox, Patrick McCarthy Tags: REVIEW Source Type: research

Registry of antithrombotic therapy in atrial fibrillation patients with bioprosthetic valves: A retrospective observational study.
CONCLUSIONS: In a current real-world setting in Japan, warfarin was the most commonly used treatment in AF patients with bioprosthetic valves, but there was an increasing trend of DOAC-treated patients. Further investigations are needed to confirm the efficacy and safety of DOAC in patients with bioprosthetic valves. PMID: 32156512 [PubMed - as supplied by publisher]
Source: Journal of Cardiology - March 6, 2020 Category: Cardiology Authors: Izumi C, Miyake M, Amano M, Kitai T, Obayashi Y, Takegami M, Kimura T, Sugio K, Matsumoto T, Nishimura K, Furukawa Y Tags: J Cardiol Source Type: research

Alternative Access Transcatheter Aortic Valve Replacement in Nonagenarians versus Younger Patients
Conclusion AA TAVR in nonagenarian patients who are not candidates for transfemoral approach can be efficaciously performed with comparable clinical outcomes to younger patients, age <90 years. Furthermore, some access sites should be avoided when possible; notably TA was associated with increased mortality, stroke, and new onset atrial fibrillation. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: The Thoracic and Cardiovascular Surgeon - April 5, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Lin, Nicole Nores, Marcos A. James, Taylor M. Rothenberg, Mark Stamou, Sotiris C. Tags: Original Cardiovascular Source Type: research

The Beneficial Effect of Anticoagulation in Aortic Bioprosthesis is Associated with its Size
Conclusion: Early anticoagulation after AVR with bioprosthesis was associated with significant decrease of transprosthesis gradient and improvement in NYHA class. These associations were seen mainly in patients with ≤ 21 mm prosthesis.
Source: Revista Brasileira de Cirurgia Cardiovascular - June 10, 2020 Category: Cardiovascular & Thoracic Surgery Source Type: research

Novel oral anticoagulant vs. warfarin in elderly atrial fibrillation patients with normal, mid ‐range, and reduced left ventricular ejection fraction
ConclusionsIn elderly AF patients ≥65 years, using NOAC was associated with lower IS/SE compared with warfarin in normal and mid‐range LVEF but not in reduced LVEF. Using NOACs was associated with lower death compared with warfarin in normal LVEF.
Source: ESC Heart Failure - July 15, 2020 Category: Cardiology Authors: Victor Chien ‐Chia Wu, Chun‐Li Wang, Cheng‐Hung Lee, Yu‐Ling Chen, Hui‐Tzu Tu, Michael Wu, Chang‐Fu Kuo, Shao‐Wei Chen, Yu‐Tung Huang, Ming‐Shien Wen, Shang‐Hung Chang Tags: Original Research Article Source Type: research

Evaluation of Prescribing Practices and Outcomes Using Direct-Acting Oral Anticoagulants After Cardiac Surgery
Clin Ther. 2021 May 30:S0149-2918(21)00203-4. doi: 10.1016/j.clinthera.2021.04.009. Online ahead of print.ABSTRACTPURPOSE: Cardiac surgery patients frequently require anticoagulation. Warfarin remains the preferred agent, and a few trials have reported negative outcomes with the use of direct-acting oral anticoagulants (DOACs) in these patients. Therefore, limited literature exists that supports the dosing, safety, and efficacy of DOACs within the cardiac surgery population.METHODS: This single-center, retrospective analysis was conducted at a tertiary academic medical center. All data were extrapolated from electronic med...
Source: Clinical Therapeutics - June 3, 2021 Category: Drugs & Pharmacology Authors: Dareen M Kanaan Bryan M Cook Julie Kelly Rhynn Malloy Source Type: research