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Condition: Atrial Fibrillation
Countries: Canada Health

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Total 200 results found since Jan 2013.

Variability in Non–Vitamin K Antagonist Oral Anticoagulants Dose Adjustment in Atrial Fibrillation Patients With Renal Dysfunction: The Influence of Renal Function Estimation Formulae
ConclusionsMDRD and CKD-EPI eGFR fail to correctly identify a significant proportion of patients who require NOAC dose adjustment, limiting their clinical utility. Cockcroft-Gault eCrCl should be calculated for all patients in whom a NOAC is being prescribed.RésuméContexteL’administration d’un nouvel anticoagulant oral non-antivitamine K (NACO) nécessite un ajustement de la dose en fonction des paramètres rénaux. La mesure de la fonction rénale la plus communément utilisée est le taux de filtration glomérulaire estimé (TFGe) selon la formule « Modified Diet in Renal Disease » (TFGe MDRD) ou « Chronic Kidne...
Source: Canadian Journal of Cardiology - July 24, 2018 Category: Cardiology Source Type: research

A clinical decision instrument to predict 30-day death and cardiovascular hospitalizations after an emergency department visit for atrial fibrillation: The Atrial Fibrillation in the Emergency Room, Part 2 (AFTER2) study
ConclusionsUsing a population-based sample, we derived and validated a tool that predicts the risk of early death and rehospitalization for a cardiovascular reason in emergency department AF patients. The tool can offer information to managing physicians about the risk of death and rehospitalization for AF patients seen in the in emergency department, as well as identify patient groups for future targeted interventions aimed at preventing these outcomes.Graphical AbstractThe Atrial Fibrillation in the Emergency Room, Part 2 (AFTER2) Study.
Source: American Heart Journal - July 24, 2018 Category: Cardiology Source Type: research

The importance and future of population screening for atrial fibrillation
Publication date: Available online 17 August 2018Source: Canadian Journal of CardiologyAuthor(s): Seung Yong Shin, Gregory Y.H. LipAbstractAtrial fibrillation (AF) is a common and progressive heart rhythm disorder that causes structural, functional and electrical remodelling of the heart. Although we do not fully understand AF yet, this arrhythmia is one clinical feature of a syndrome that is represented by irregularly irregular atrial rhythm accompanied by progressive atrial structural and functional remodelling. Although ischemic stroke, most feared complication of AF, can be prevented by anticoagulation, asymptomatic or...
Source: Canadian Journal of Cardiology - August 18, 2018 Category: Cardiology Source Type: research

Reply to Green et al.—Elevated Incidence of Atrial Fibrillation and Stroke in Patients With Atrial Flutter: A Population-Based Study
Publication date: September 2018Source: Canadian Journal of Cardiology, Volume 34, Issue 9Author(s): Lorne J. Gula, Damian P Redfearn, Krista B. Jenkyn, Britney Allen, Allan C. Skanes, Peter Leong-Sit, Salimah Z. Shariff
Source: Canadian Journal of Cardiology - August 29, 2018 Category: Cardiology Source Type: research

New Insights into the Use of Cardiac Magnetic Resonance Imaging to Guide Decision Making in Atrial Fibrillation Management
Publication date: Available online 12 July 2018Source: Canadian Journal of CardiologyAuthor(s): Tarek Zghaib, Saman NazarianAbstractRecent advances in cardiac magnetic resonance (CMR) imaging acquisition techniques have enabled the visualization of thin atrial myocardium with high temporal and spatial resolution and have the potential to shift atrial fibrillation (AF) management paradigms. Late gadolinium-enhancement (LGE)-CMR can noninvasively identify atrial arrhythmogenic scar substrates and has been shown to spatially correlate with low-voltage areas. Immediately after ablation, a combination of native T1-weighted, LGE...
Source: Canadian Journal of Cardiology - October 6, 2018 Category: Cardiology Source Type: research

The Canadian Community Utilization of Stroke Prevention Study in Atrial Fibrillation in the Emergency Department (C-CUSP ED)
ConclusionAn oral anticoagulation prescription tool was associated with an increase in new oral anticoagulation prescription in the ED, irrespective of whether an atrial fibrillation clinic follow-up was scheduled. The use of an atrial fibrillation clinic was associated with a trend to a higher rate of oral anticoagulation at 6-month follow-up.
Source: Annals of Emergency Medicine - October 27, 2018 Category: Emergency Medicine Source Type: research

Descriptive analysis of pharmacy services provided after community pharmacy screening
Conclusions Approximately one-third of participants received a pharmacy service within 3  months post-screening. Relatively large numbers of annual and follow-up medication reviews were delivered despite low eligibility for annual-only reviews and despite many missed opportunities for pharmacy service provision in at-risk patients. In-pharmacy screening may facilitate provision of some services, namely medication reviews, by providing opportunities to identify patients at-risk.
Source: International Journal of Clinical Pharmacy - November 26, 2018 Category: Drugs & Pharmacology Source Type: research

Stroke Prevention, Evaluation of Bleeding Risk and Anticoagulant Treatment Management in Atrial Fibrillation Contemporary International Guidelines
Publication date: Available online 21 February 2019Source: Canadian Journal of CardiologyAuthor(s): Marco Proietti, Deirdre A. Lane, Giuseppe Boriani, Gregory Y.H. LipAbstractIn recent years the management of AF patients has progressively and substantially changed due to the introduction of new treatments and the availability of new data regarding the epidemiology and clinical management of these patients. In the last two years alone, there have been seven new guidelines or guideline updates that have been published, introducing new recommendations and significantly revising previously published ones. Two updates for Canad...
Source: Canadian Journal of Cardiology - February 22, 2019 Category: Cardiology Source Type: research

Direct Oral Anticoagulants in Cirrhotic Patients: Current Evidence and Clinical Observations.
Authors: Elhosseiny S, Al Moussawi H, Chalhoub JM, Lafferty J, Deeb L Abstract The introduction of Direct Oral Anticoagulants (DOACs) to the pharmaceutical market provided patients and clinicians with novel convenient and safe options of anticoagulation. The use of this class of medications is currently limited to venous thromboembolic therapy and prophylaxis, in addition to stroke prophylaxis in patients with nonvalvular atrial fibrillation. Despite their altered hemostasis, patients with cirrhosis are thought to be in a procoagulant state and thus prone to thrombus formation. Patients with cirrhosis might benefit...
Source: Canadian Journal of Gastroenterology - February 24, 2019 Category: Gastroenterology Tags: Can J Gastroenterol Hepatol Source Type: research

Higher hospital readmission rates for cardiac patients in Northern vs. Southern Ontario: Importance
(Elsevier) Patients hospitalized with heart attacks, heart failure, atrial fibrillation or stroke in Northern Ontario, Canada, were more likely to be readmitted to the hospital and repeatedly hospitalized after discharge than those living in Southern Ontario. Yet, no geographical differences were found in 30-day survival. A new study recommends providing access to timely transitional care by clinicians who have the knowledge and expertise to treat patients recently discharged from hospital as one of several strategies necessary to reduce hospital readmission rates.
Source: EurekAlert! - Medicine and Health - February 28, 2019 Category: International Medicine & Public Health Source Type: news

Screening for Atrial Fibrillation using a Mobile, Single-Lead Electrocardiogram in Canadian Primary Care Clinics
ConclusionPreviously undiagnosed AF is common in older individuals attending primary care clinics. The Kardia Mobile ECG device appears to be an effective screening tool for AF with high physician acceptability. More research on the feasibility of such novel technologies is warranted for future consideration of integration in population-based screening programs.
Source: Canadian Journal of Cardiology - April 6, 2019 Category: Cardiology Source Type: research

Atrial Transcriptional Profiles of Molecular Targets Mediating Electrophysiological Function in Aging and Pgc-1 β Deficient Murine Hearts
Conclusion: These findings limit the possible roles of gene transcriptional changes in previously reported age-dependent pro-arrhythmic electrophysiologial changes observed in Pgc-1β-/- atria to an altered Ca2+-ATPase (Atp2a2) expression. This directly parallels previously reported arrhythmic mechanism associated with p21-activated kinase type 1 deficiency. This could add to contributions from the direct physiological outcomes of mitochondrial dysfunction, whether through reactive oxygen species (ROS) production or altered Ca2+ homeostasis. Introduction Atrial arrhythmias constitute a major public health pro...
Source: Frontiers in Physiology - April 23, 2019 Category: Physiology Source Type: research

Stroke Prevention, Evaluation of Bleeding Risk, and Anticoagulant Treatment Management in Atrial Fibrillation Contemporary International Guidelines
Publication date: May 2019Source: Canadian Journal of Cardiology, Volume 35, Issue 5Author(s): Marco Proietti, Deirdre A. Lane, Giuseppe Boriani, Gregory Y.H. LipAbstractIn recent years the management of atrial fibrillation patients has progressively and substantially changed because of the introduction of new treatments and the availability of new data regarding the epidemiology and clinical management of these patients. In the past 2 years alone, there have been 7 new guidelines or guideline updates that have been published, which have introduced new recommendations and significantly revised previously published ones. Tw...
Source: Canadian Journal of Cardiology - April 27, 2019 Category: Cardiology Source Type: research

Arrhythmias in Adults with Congenital Heart Disease: What the Practicing Cardiologist Needs to Know
Publication date: Available online 16 July 2019Source: Canadian Journal of CardiologyAuthor(s): Paul KhairyAbstractThe expanding population of adults with congenital heart disease (CHD) combined with the pervasiveness of arrhythmias has resulted in the rapid growth of a dedicated sector of cardiology at the intersection between two subspecialties: electrophysiology and adult CHD. Herein, practical considerations are offered regarding urgent referral for catheter ablation of atrial arrhythmias, anticoagulation, and primary prevention implantable cardioverter-defibrillators (ICDs). Patients with Ebstein anomaly and ventricul...
Source: Canadian Journal of Cardiology - July 17, 2019 Category: Cardiology Source Type: research

Self-Reported Daytime Sleepiness and Sleep-Disordered Breathing in Patients with Atrial Fibrillation: SNOozE-AF
ConclusionsIn an ambulatory AF population, SDB was common but most patients reported low daytime sleepiness levels. Clinical features, rather than daytime sleepiness, were predictive of patients with moderate-to-severe SDB. Lack of excessive daytime sleepiness should not preclude patients from being investigated for the potential presence of concomitant SDB
Source: Canadian Journal of Cardiology - August 2, 2019 Category: Cardiology Source Type: research