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Specialty: Cardiology
Condition: Thrombosis

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Total 3531 results found since Jan 2013.

Ischaemic and haemorrhagic stroke associated with non-vitamin K antagonist oral anticoagulants and warfarin use in patients with atrial fibrillation: a nationwide cohort study
Conclusions</div>Among anticoagulant-naïve AF patients, treatment with NOACs was not associated with significantly lower risk of stroke/TE compared with VKA, but intracranial bleeding risk was significantly lower with dabigatran and apixaban.</span>
Source: European Heart Journal - October 14, 2016 Category: Cardiology Source Type: research

Here today, gone tomorrow: The laa and stroke
Stroke prevention in the setting of non-valvular atrial fibrillation continues to attract great clinical interest,[1,2] the result of several known issues including: 1) the high morbidity and mortality associated with stroke which is the number one cause of death and disability, 2) the frequency of non-valvular atrial fibrillation (NVAF) and its association with an increased incidence of stroke – greater than 20% of strokes particularly in elderly patients are related to the NVAF, 3) the findings that approximately 90% of strokes in this setting are related to thrombus in the left atrial appendage (LAA),[3] 4) anticoagul...
Source: Trends in Cardiovascular Medicine - April 11, 2017 Category: Cardiology Authors: Paul Friedman, David R. Holmes Source Type: research

Editorial commentary: Here today, gone tomorrow: The LAA and stroke
Stroke prevention in the setting of non-valvular atrial fibrillation (NVAF) continues to attract great clinical interest [1,2], the result of several known issues including (1) the high morbidity and mortality associated with stroke, which is the number one cause of death and disability, (2) the frequency of non-valvular atrial fibrillation and its association with an increased incidence of stroke —greater than 20% of strokes particularly in elderly patients are related to the NVAF, (3) the findings that approximately 90% of strokes in this setting are related to thrombus in the left atrial appendage (LAA) [3], (4) antic...
Source: Trends in Cardiovascular Medicine - April 11, 2017 Category: Cardiology Authors: Paul A. Friedman, David R. Holmes Source Type: research

Blood pressure and in-hospital outcomes in patients presenting with ischaemic stroke
ConclusionIn patients hospitalized with ischaemic stroke, J-shaped, or U-shaped relationships were observed between BP variables and short-term outcomes. However, haemorrhagic complications with thrombolytic therapy were lower with lower BP.
Source: European Heart Journal - June 30, 2017 Category: Cardiology Source Type: research

Factors Associated with Intima-Media Complex Thickness of the Common Carotid Artery in Japanese Noncardioembolic Stroke Patients with Hyperlipidemia: The J-STARS Echo Study.
CONCLUSION: Baseline mean and maximum values of carotid IMT in Japanese noncardioembolic stroke patients with hyperlipidemia were 0.89±0.15 mm and 1.19±0.32 mm, respectively, which were similar to those previously reported from Western countries. Age, smoking, hypertension, HDL cholesterol, and diabetes mellitus were associated with mean IMT, and those, except for hypertension, were associated with maximum IMT. PMID: 29118311 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - November 11, 2017 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Is von Willebrand factor associated with stroke and death at mid-term in patients with non-valvular atrial fibrillation?
CONCLUSIONS: High vWF plasma concentrations may discriminate patients with NVAF at greater risk of stroke or all-cause death. PMID: 29685722 [PubMed - as supplied by publisher]
Source: Archives of Cardiovascular Diseases - April 20, 2018 Category: Cardiology Authors: Ancedy Y, Berthelot E, Lang S, Ederhy S, Boyer-Chatenet L, Di Angelantonio E, Soulat-Dufour L, Etienney A, Adavane-Scheublé S, Boccara F, Cohen A Tags: Arch Cardiovasc Dis Source Type: research

Non-High-Density Lipoprotein Cholesterol and Risk of Stroke Subtypes and Coronary Heart Disease: The Japan Public Health Center-Based Prospective (JPHC) Study.
CONCLUSIONS: In Japanese men, lower non-HDL-C levels were associated with a decreased risk of large-artery occlusive infarction and an increased risk of ICH, particularly lobar ICH. PMID: 31534078 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - September 20, 2019 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Homocysteine Level Predicts Response to Dual Antiplatelet in Women With Minor Stroke or Transient Ischemic Attack: Subanalysis of the CHANCE Trial.
CONCLUSIONS: Homocysteine could be a potential biomarker to discriminate the effects of dual and single antiplatelet therapy in female patients with minor ischemic stroke or high-risk transient ischemic attack. CLINICAL TRIAL REGISTRATION: URL: http://www.clinicaltrials.gov. Unique identifier: NCT00979589. PMID: 31941381 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - January 15, 2020 Category: Cardiology Authors: Li J, Wang Y, Li H, Zuo Z, Lin J, Wang A, Zhao X, Liu L, Wang Y, CHANCE Investigators* Tags: Arterioscler Thromb Vasc Biol Source Type: research

Structural heart intervention for prevention of embolic and hemorrhagic stroke: The new field of neurocardiology.
Abstract Cardiogenic stroke (CS), characteristic causes of which include atrial fibrillation (AF) and right-to-left shunting due to a patent foramen ovale (PFO), has a well-known tendency to be associated with a more extensive ischemic area. This may result in severe neurological damage, and require strict life-long antithrombotic therapy. However, the fact that some patients have problems complying with the requirement for extended oral antithrombotic treatment has motivated the development of alternative approaches for stroke prevention. Heart structures such as the left atrial appendage (LAA) and PFO are potent...
Source: Journal of Cardiology - May 28, 2020 Category: Cardiology Authors: Morino Y, Nakajima Y Tags: J Cardiol Source Type: research

Atrial Fibrillation With and Without Cardiovascular Risk Factors and Stroke Mortality.
CONCLUSIONS: AF was found to be an independent risk factor for stroke and total cardiovascular mortality even in individuals without other TCVRFs. PMID: 32554949 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - June 20, 2020 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Plasma D ‐dimer concentrations predicting stroke risk and rivaroxaban benefit in patients with heart failure and sinus rhythm: an analysis from the COMMANDER‐HF trial
ConclusionIn COMMANDER ‐HF, rivaroxaban reduced the risk of stroke but the benefit may be confined to patients with D‐dimer concentrations above 515ng/mL. Prospective trials are warranted to confirm these findings.
Source: European Journal of Heart Failure - September 20, 2020 Category: Cardiology Authors: Jo ão Pedro Ferreira, Carolyn S. P. Lam, Stefan D. Anker, Mandeep R. Mehra, Dirk J. Veldhuisen, William M. Byra, David A. La Police, John G. F. Cleland, Barry Greenberg, Faiez Zannad Tags: Research Article Source Type: research

Leukocyte Count and Risks of Stroke and Coronary Heart Disease: The Circulatory Risk in Communities Study (CIRCS)
CONCLUSION: Leukocyte count was positively associated with the risks of ischemic stroke and coronary heart disease among the general Japanese population, especially in current smokers.PMID:33746157 | DOI:10.5551/jat.60889
Source: Journal of Atherosclerosis and Thrombosis - March 22, 2021 Category: Cardiology Authors: Jiaqi Li Hironori Imano Kazumasa Yamagishi Mari Tanaka Renzhe Cui Isao Muraki Mitsumasa Umesawa Mina Hayama-Terada Tetsuya Ohira Masahiko Kiyama Takeo Okada Tomoko Sankai Takeshi Tanigawa Akihiko Kitamura Hiroyasu Iso CIRCS Investigators Source Type: research