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Condition: Thrombosis
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Total 29 results found since Jan 2013.

Influence of Sex on Stroke Prognosis: A Demographic, Clinical, and Molecular Analysis
Conclusion Our data suggest that women who suffer from IS present with a poorer functional outcome than men at 3-months, regardless of other preclinical and clinical factors during the acute phase. These relationships seem to be mediated by atrial dysfunction and inflammation. The inflammatory response is slightly higher in women; however, there are no sex differences in their functional behavior. There is a probable relationship between the molecular marker of atrial dysfunction NT-proBNP and worse functional outcome in women, and the connection seems to be more important in cardioembolic stroke patients. In patients wi...
Source: Frontiers in Neurology - April 16, 2019 Category: Neurology Source Type: research

Differences Between New Immigrants From the Former Soviet Union and Veteran Residents in Knowledge, Perception, and Risk Factors of Stroke.
CONCLUSIONS: Veteran residents showed lower levels of knowledge about stroke. Educational campaigns aimed at increasing knowledge of stroke among Israel's general population in Israel, as well as culturally targeting specific subgroups, are recommended. PMID: 26132280 [PubMed - as supplied by publisher]
Source: The Journal of Cardiovascular Nursing - July 1, 2015 Category: Nursing Authors: Melnikov S, Itzhaki M, Koton S Tags: J Cardiovasc Nurs Source Type: research

Reducing Time to Treatment - The Role of Stroke Neurologist as First Responder (S5.006)
CONCLUSIONS: The use of a stroke-trained attending neurologist as a first responder and stroke team leader resulted in rapid patient evaluation and faster decision regarding thrombolytic therapy, improving time to treatment and time to CT.Disclosure: Dr. Ozark has nothing to disclose. Dr. Sabatino has nothing to disclose. Dr. Holmstedt has nothing to disclose. Dr. Turan has received personal compensation for activities with Gore Laboratories Inc., and Boehringer Ingelheim Pharmaceuticals Inc. Dr. Turan has received research support from Stryker Co., the National Institutes of Health, and AstraZeneca.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Ozark, S., Sabatino, P., Holmstedt, C., Turan, T. Tags: Cerebrovascular Disease and Interventional Neurology: Pre-hospital, Telemedicine, and Related Topics Source Type: research

Poor Awareness of Stroke—A Hospital-Based Study from South India: An Urgent Need For Awareness Programs
Background: Stroke treatment has reached a new benchmark with thrombolytic therapy. However, India has witnessed a tremendous increase in morbidity and mortality of stroke over the past few decades. The prime deciding factor is initiation of treatment within the time window, which requires early recognition of stroke symptoms. We wished to analyze the lacunae in the stroke knowledge in our population. This hospital-based study assessed awareness of the public regarding stroke.Methods: Two trained medical students interviewed accompanying relatives using a structured questionnaire. Data were analyzed using Statistical Packa...
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2014 Category: Neurology Authors: Bindu Menon, Jatla J. Swaroop, Haripuram K.R. Deepika, Jyothi Conjeevaram, K. Munisusmitha Tags: Original Articles Source Type: research

A Novel Method for Measuring Oxidative Stress in Patients with Stroke Symptoms (S52.005)
CONCLUSIONS: These results demonstrate the ability of ORP to identify oxidative stress and amount of antioxidant reserves in a stroke population. We propose ORP monitoring as a potentially useful tool in evaluation of acute stroke patients.Disclosure: Dr. Wagner has received personal compensation for activities with Genentech, Inc. Dr. Salottolo has nothing to disclose. Dr. Fanale has received personal compensation for activities with Genentech, Inc. as a speaker. Dr. Whaley has nothing to disclose. Dr. McCarthy has nothing to disclose. Luoxis Diagnostics, Inc,
Source: Neurology - April 8, 2015 Category: Neurology Authors: Wagner, J., Salottolo, K., Fanale, C., Whaley, M., McCarthy, K., BarOr, D. Tags: General Neurology: Neural Networks and Neuromodulation Source Type: research

Predictive Value of Globulin to Prealbumin Ratio for 3-Month Functional Outcomes in Acute Ischemic Stroke Patients
CONCLUSIONS: The 24 h GPR level can predict the 3-month functional outcome in AIS patients accepting recombinant tissue plasminogen activator (r-tPA) intravenous thrombosis.PMID:35340417 | PMC:PMC8947872 | DOI:10.1155/2022/1120192
Source: Disease Markers - March 28, 2022 Category: Laboratory Medicine Authors: Chunjian Li Chenguang Yang Junyan Zhu Honghao Huang Jiahui Zheng Xueting Hu Wenjing Pan Fangyue Sun Tian Zeng Haojie Qiu Zerui Jiang Yiqun Chen Yilin Chen Guangyong Chen Yiyun Weng Source Type: research

Quantitative assessment of hyperacute cerebral infarction with intravoxel incoherent motion MR imaging: Initial experience in a canine stroke model
ConclusionIVIM imaging could simultaneously evaluate the diffusion and microvascular perfusion characteristics in hyperacute strokes.Level of Evidence:2J. Magn. Reson. Imaging 2016
Source: Journal of Magnetic Resonance Imaging - November 29, 2016 Category: Radiology Authors: Qian ‐Qian Gao, Shan‐Shan Lu, Xiao‐Quan Xu, Cheng‐Jiang Wu, Xing‐Long Liu, Sheng Liu, Hai‐Bin Shi Tags: Original Research Source Type: research

Biosimilar tenecteplase versus alteplase in acute ischemic stroke: A real world study
Conclusion: This present study observed no difference in the efficacy and safety between biosimilar TNK and rTPA. Our findings are in concordance with published trials showing equivalence between the two molecules.
Source: Annals of Indian Academy of Neurology - January 25, 2023 Category: Neurology Authors: Ayush Mohan Snigdha Komakula Suhas Murali Pooja Anand Dyuti Shah VY Vishnu Awadh Kishor Pandit Ayush Agarwal Deepti Vibha Mamta Bhushan Singh MV Padma Srivastava Rohit Bhatia Source Type: research

Biosimilar Tenecteplase Versus Alteplase in Acute Ischemic Stroke: A Real World Study
CONCLUSION: This present study observed no difference in the efficacy and safety between biosimilar TNK and rTPA. Our findings are in concordance with published trials showing equivalence between the two molecules.PMID:37034051 | PMC:PMC10081554 | DOI:10.4103/aian.aian_754_22
Source: Atherosclerosis - April 10, 2023 Category: Cardiology Authors: Ayush Mohan Snigdha Komakula Suhas Murali Pooja Anand Dyuti Shah V Y Vishnu Awadh Kishor Pandit Ayush Agarwal Deepti Vibha Mamta Bhushan Singh M V Padma Srivastava Rohit Bhatia Source Type: research

A Serious Diagnosis Lacking Common Symptoms
​BY JENNIFER TUONG; IVAN KHARCHENKO; JEAN LUC AGARD; & AHMED RAZIUDDIN, MDA 65-year-old man who had HIV well-controlled with highly active antiretroviral therapy, hypertension, sciatica, and restless leg syndrome presented to the emergency department with left leg pain. He also had had chemotherapy and radiation for anal cancer. The patient said the pain had started 45 minutes earlier when he was sitting on the toilet.He described the pain as sore in quality and 10/10 on the pain scale. He reported that it had started in his lower back and radiated to his left leg. He said he had had no trauma or weakness to the regi...
Source: The Case Files - May 28, 2019 Category: Emergency Medicine Tags: Blog Posts Source Type: research

Hemodynamic Characteristics Associated With Paraclinoid Aneurysm Recurrence in Patients After Embolization
Conclusions: High peak systolic WSS, OSI and velocity around aneurysm neck areas after embolization of paraclinoidal aneurysms may be important factors leading to recurrence. Introduction Paraclinoid aneurysms are defined as aneurysms arising from the segment of the internal carotid artery (ICA) between the distal dural ring and the origin of the posterior communicating artery. They account for approximately 1.3–5% of all intracranial aneurysms and they comprise the majority of such aneurysms in females (1–3). Hemodynamic characteristics are thought to be the most important risk factors for occurrence...
Source: Frontiers in Neurology - April 24, 2019 Category: Neurology Source Type: research

The Oversimplification of Cholesterol Testing Can Be Deadly
Early every year, countless Americans embark on a new fitness regime. They go for a physical and maybe for a blood test to measure cholesterol levels. After a clean bill of health, they might train to run a 10K, a marathon or even an Iron man. But what if those tests do not provide a complete picture of your health? What if you are on the verge of a heart attack and have no idea? Before 30, when the human body is at its peak, it can take the strain of being pushed to the limit. As we age, however, cellular changes and the expression of genetic predispositions can dramatically alter our health. Conventional medical tests a...
Source: Healthy Living - The Huffington Post - April 6, 2016 Category: Consumer Health News Source Type: news

Plasma Metal Concentrations and Incident Coronary Heart Disease in Chinese Adults: The Dongfeng-Tongji Cohort
Conclusions: Our study suggested that incident CHD was positively associated with plasma levels of titanium and arsenic, and inversely associated with selenium. Additional research is needed to confirm these findings in other populations. https://doi.org/10.1289/EHP1521 Received: 22 December 2016 Revised: 17 September 2017 Accepted: 19 September 2017 Published: 19 October 2017 Address correspondence to T. Wu, or A. Pan, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, 13 Hongkong Rd., Wuhan 430030, Hubei, China. Telephone: +86-27-83692347. Email: wut@mails.tjmu.edu.cn or p...
Source: EHP Research - October 20, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Severe Symptoms, but a Truly Treatable Disease
​BY NOURA MAHDI; DARRON LEWIS; JEREMY OSBORNE; & AHMED RAZIUDDIN, MDA 73-year-old man was brought to the emergency department from his nursing home for rectal bleeding and anemia. The patient mentioned he had had episodes of bright red rectal bleeding and constipation for a few months. A colonoscopy had been done prior to the visit, which revealed a large intestine tumor and biopsy confirming adenocarcinoma. He was awaiting an appointment with his surgeon.The patient reported bloody rectal leakage, and a CBC done at the nursing home showed a hemoglobin level of 7.2. He also complained of dyspnea but denied any other ...
Source: The Case Files - March 20, 2018 Category: Emergency Medicine Tags: Blog Posts Source Type: research