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Total 296 results found since Jan 2013.

Self ‐Propulsion of a Light‐Powered Microscopic Crystalline Flapper in Water
This study reports, for the first time, the experimental realization of directional swimming of a microcrystal that exhibits self-continuous reciprocating motion in a 2D water tank. Although the reciprocal flip motion of the crystals is like that of a fish wagging its tail fin, many of the crystals swam in the opposite direction to which a fish would swim. Here the directionality generation mechanism and physical features of the swimming behavior is explored by constructing a mathematical model for the crystalline flapper. The results show that a tiny crystal with a less-deformable part in its flip fin exhibits a pull-type...
Source: Small - November 27, 2021 Category: Nanotechnology Authors: Kazuma Obara, Yoshiyuki Kageyama, Sadamu Takeda Tags: Research Article Source Type: research

High-Dose Marine Omega-3s Raise Risk for Atrial Fibrillation High-Dose Marine Omega-3s Raise Risk for Atrial Fibrillation
Dr JoAnn Manson discusses the link between fish oil supplements, AF, and stroke.Medscape Ob/Gyn
Source: Medscape Today Headlines - November 17, 2021 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health Commentary Source Type: news

A score appraising Paleolithic diet and the risk of cardiovascular disease in a Mediterranean prospective cohort
ConclusionsOur findings suggest that the PaleoDiet may have cardiovascular benefits in participants from a Mediterranean country. Avoidance of ultra-processed foods seems to play a key role in this inverse association.
Source: European Journal of Nutrition - October 21, 2021 Category: Nutrition Source Type: research

Oil induced cardiac effects in embryonic sheepshead minnows, Cyprinodon variegatus
This study aims to fill these knowledge gaps and provide a more holistic approach for assessing the effects of PAHs on cardiac function by exposing sheepshead minnow (Cyprinodon variegatus) embryos to two oil doses (150 and 300 μg/L tPAH nominally) throughout embryonic development and measuring cardiac responses through the identification of cardiotoxic phenotypes (pericardial edema) as well as calculation of cardiac output at 4 days post fertilization. Results of this study show significant increases in pericardial edema at both oil doses relative to controls as well as significantly reduced cardiac output - driven by re...
Source: Chemosphere - October 10, 2021 Category: Chemistry Authors: Elizabeth Allmon Grace Carter Robert Griffitt Maria S Sep úlveda Source Type: research

Continuous gastric saline perfusion elicits cardiovascular responses in freshwater rainbow trout (Oncorhynchus mykiss)
AbstractWhen in seawater, rainbow trout (Oncorhynchus mykiss) drink to avoid dehydration and display stroke volume (SV) mediated elevations in cardiac output (CO) and an increased proportion of CO is diverted to the gastrointestinal tract as compared to when in freshwater. These cardiovascular alterations are associated with distinct reductions in systemic and gastrointestinal vascular resistance (RSys andRGI, respectively). Although increased gastrointestinal blood flow (GBF) is likely essential for osmoregulation in seawater, the sensory functions and mechanisms driving the vascular resistance changes and other associate...
Source: Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology - October 7, 2021 Category: Physiology Source Type: research

Long Non-coding RNA PVT1 Inhibits miR-30c-5p to Upregulate Rock2 to Modulate Cerebral Ischemia/Reperfusion Injury Through MAPK Signaling Pathway Activation
AbstractLong non-coding RNAs (lncRNAs) play a key role in a variety of disease processes. Plasmacytoma variant translocation 1 (PVT1), a lncRNA, is known to regulate cell functions and play a key role in the pathogenesis of many malignant tumors. The function and molecular mechanisms of lncRNA-PVT1 in cerebral ischemia remain unknown. Real-time PCR (qRT-PCR) was used to detect lncRNA-PVT1 and microRNA-30c-5p (miR-30c-5p) expression in the brain tissues of mice underwent middle cerebral artery occlusion/reperfusion (MCAO/R) and oxygen –glucose deprivation/reperfusion (OGD/R)-treated mouse primary brain neurons. Gain- or l...
Source: Molecular Neurobiology - August 26, 2021 Category: Neurology Source Type: research

Circulating Extracellular Vesicle Cargo as Bioinformants of ‘at-risk’ Carotid Artery Stenosis
Carotid artery atherosclerosis is a major cause of ischemic stroke. Managing patients with asymptomatic disease remains challenging, given the lack of reliable tests to identify the subgroup of patients prone to plaque progression and stroke. Given the functional and diagnostic roles of extracellular vesicle (EV) contents, we hypothesized that plasma EV-derived microRNA (miRNA) differs between symptomatic and asymptomatic patients.
Source: Journal of Vascular Surgery - August 24, 2021 Category: Surgery Authors: Sneha Raju, Dakota Gustafson, Kamalben Prajapati, Natalie J. Galant, Steven R. Botts, Giuseppe Papia, Jason E. Fish, Kathryn L. Howe Tags: PC: Poster Competition Source Type: research

Streamwise and lateral maneuvers of a fish-inspired hydrofoil
Fish are highly maneuverable compared to human-made underwater vehicles. Maneuvers are inherently transient, so they are often studied via observations of fish and fish-like robots, where their dynamics cannot be recorded directly. To study maneuvers in isolation, we designed a new kind of wireless carriage whose air bushings allow a hydrofoil to maneuver semi-autonomously in a water channel. We show that modulating the hydrofoil's frequency, amplitude, pitch bias, and stroke speed ratio (pitching speed of left vs right stroke) produces streamwise and lateral maneuvers with mixed effectiveness. Modulating pitch bias,...
Source: Bioinspiration and Biomimetics - August 24, 2021 Category: Science Authors: Qiang Zhong and Daniel B Quinn Source Type: research

Efficacy of virtual reality therapy in ideomotor apraxia rehabilitation: A case report
We report the possible therapeutic efficacy of immersive virtual reality (VR) rehabilitation for the treatment of ideomotor apraxia in a patient with stroke. Patient concerns: A 56-year-old man with sudden weakness of his left side caused by right frontal, parietal, and corpus callosal infarction was transferred to rehabilitation medicine center for intensive rehabilitation. Although his left-sided weakness had almost subsided 10 days after the onset of symptoms, he presented difficulty using his left hand and required assistance in most activities of daily living. Diagnoses: Ideomotor apraxia in a patient wi...
Source: Medicine - July 16, 2021 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Knockdown of XIST Attenuates Cerebral Ischemia/Reperfusion Injury Through Regulation of miR-362/ROCK2 Axis
In conclusion, depletion of XIST attenuated I/R-induced neurological impairment and inflammatory response via the miR-362/ROCK2 axis. These findings offer a potential novel strategy for ischemic stroke therapy.PMID:34037903 | DOI:10.1007/s11064-021-03354-6
Source: Neurochemical Research - May 26, 2021 Category: Neuroscience Authors: Jingtao Wang Zhenqiang Fu Menghan Wang Jingjing Lu Hecheng Yang Hong Lu Source Type: research

Therapeutic Nuclear Magnetic Resonance affects the core clock mechanism and associated Hypoxia-inducible factor-1
Chronobiol Int. 2021 Apr 13:1-15. doi: 10.1080/07420528.2021.1910288. Online ahead of print.ABSTRACTThe influence of low intensity electromagnetic fields on circadian clocks of cells and tissues has gained increasing scientific interest, either as a therapeutic tool or as a potential environmental hazard. Nuclear Magnetic Resonance (NMR) refers to the property of certain atomic nuclei to absorb the energy of radio waves under a corresponding magnetic field. NMR forms the basis for Magnetic Resonance Imaging, Magnetic Resonance Spectroscopy and, in a low-intensity form, for NMR therapy (tNMR). Since the circadian clock is b...
Source: Chronobiology International - April 13, 2021 Category: Biology Authors: Viktoria Th öni Regina Oliva David Mauracher Margit Egg Source Type: research