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Clinical characteristics and predictors for in-hospital mortality in adult COVID-19 patients: A retrospective single center cohort study in Vilnius, Lithuania
ConclusionsAge, congestive heart failure, obesity, COPD, prior stroke, and increased concentration of urea, LDH, CRP, IL-6, troponin I, ALT to AST ratio were identified to be the predictors for in-hospital mortality of COVID-19 patients.
Source: PLoS One - August 25, 2023 Category: Biomedical Science Authors: Ieva Kubiliute Source Type: research

Progression of stroke risk in patients aged & lt;65 years diagnosed with atrial fibrillation: a cohort study in general practice
CONCLUSION: People aged <65 years with AF are at higher risk of developing hypertension, heart failure, and diabetes than the general population, so may warrant regular review to identify new occurrence of such risk factors.PMID:37487643 | DOI:10.3399/BJGP.2022.0568
Source: The British Journal of General Practice - July 24, 2023 Category: Primary Care Authors: Silvia C Mendon ça Duncan A Edwards Jenny Lund Catherine L Saunders Jonathan Mant Source Type: research

Observational Study of Patients Hospitalized With Neurologic Events After SARS-CoV-2 Vaccination, December 2020-June 2021
Discussion All cases in this study were determined to have at least 1 risk factor and/or known etiology accounting for their neurologic syndromes. Our comprehensive clinical review of these cases supports the safety of mRNA COVID-19 vaccines.
Source: Neurology Clinical Practice - May 25, 2023 Category: Neurology Authors: Kim, C. Y., McNeill, E. N., Young, C., King, F., Clague, M., Caldwell, M., Boruah, A., Zucker, J., Thakur, K. T. Tags: Autoimmune diseases, Post-infectious, Inclusion, Diversity, Equity, Anti-racism, and Social Justice (IDEAS), COVID-19 Research Article Source Type: research

Adverse events following COVID ‐19 mRNA vaccines: A systematic review of cardiovascular complication, thrombosis, and thrombocytopenia
ConclusionAvailable literature includes more studies with the BNT162b2 vaccine than mRNA-1273. Future studies must report mortality and adverse cardiovascular events by vaccine types.
Source: Immunity, Inflammation and Disease - March 17, 2023 Category: Allergy & Immunology Authors: Farah Yasmin, Hala Najeeb, Unaiza Naeem, Abdul Moeed, Abdul Raafe Atif, Muhammad Sohaib Asghar, Nayef Nimri, Maryam Saleem, Dhrubajyoti Bandyopadhyay, Chayakrit Krittanawong, Mohammed Mahmmoud Fadelallah Eljack, Muhammad Junaid Tahir, Fahad Wa Tags: REVIEW ARTICLE Source Type: research

Analysis of HLA Variants and Graves ’ Disease and Its Comorbidities Using a High Resolution Imputation System to Examine Electronic Medical Health Records
Hyperthyroidism is a prevalent endocrine disorder, and genetics play a major role in the development of thyroid-associated diseases. In particular, the inheritance of HLA has been demonstrated to induce the highest susceptibility to Graves’ disease (GD). However, thus far, no studies have reported the contribution of HLA to the development of GD and the complications that follow. Thus, in the present study, to the best of our knowledge, for the first time, a powerful imputation method, HIBAG, was used to predict the HLA subtypes among populations with available genome-wide SNP array data from the China Medical University...
Source: Frontiers in Endocrinology - March 7, 2022 Category: Endocrinology Source Type: research

Antihypertensive treatment and risk factors for syncope in asymptomatic aortic stenosis patients with hypertension
CONCLUSIONS: In patients with moderate or severe AS, concomitant hypertension, and antihypertensive treatment didn't increase the occurrence of syncope, whereas higher ZVA was independently associated with greater risk of syncope.PMID:34872422 | DOI:10.1080/10641963.2021.1883047
Source: Clinical and Experimental Hypertension - December 7, 2021 Category: Cardiology Authors: Meihua Wu Ping Gu Qianqiang Cao Aibin Gong Wenliang Tan Dezhi Hong Source Type: research

Impacts of type 2 diabetes mellitus and hypertension on the incidence of cardiovascular diseases and stroke in China real-world setting: a retrospective cohort study
Conclusion T2DM and HTN were strongly associated with combined VE and stroke risk; however, the HTN-only group had a higher combined VE and stroke risk than the T2DM-only group.
Source: BMJ Open - November 29, 2021 Category: General Medicine Authors: Liu, Y., Li, J., Dou, Y., Ma, H. Tags: Open access, Diabetes and Endocrinology Source Type: research

Pleiotropy of systemic lupus erythematosus risk alleles and cardiometabolic disorders: A phenome-wide association study and inverse-variance weighted meta-analysis
CONCLUSION: A weighted GRS for SLE was associated with an increased risk of several autoimmune-related phenotypes including type I diabetes but not with cardiometabolic disorders.PMID:33977795 | DOI:10.1177/09612033211014952
Source: Lupus - May 12, 2021 Category: Rheumatology Authors: Vivian K Kawai Mingjian Shi Ge Liu QiPing Feng WeiQi Wei Cecilia P Chung Theresa L Walunas Adam S Gordon James G Linneman Scott J Hebbring John B Harley Nancy J Cox Dan M Roden C Michael Stein Jonathan D Mosley Source Type: research

Higher Mortality of Ischaemic Stroke Patients Hospitalized with COVID-19 Compared to Historical Controls
Conclusions: Ischaemic stroke patients with COVID-19 had significantly higher 60-day all-cause mortality compared to propensity score-matched historical controls (ischaemic stroke patients without COVID-19).Cerebrovasc Dis
Source: Cerebrovascular Diseases - March 26, 2021 Category: Neurology Source Type: research

Intraoperative Ischemic Stroke in Elective Spine Surgery: A Retrospective Study of Incidence and Risk
Conclusion. . With the increase of spinal procedures, it is important to identify patients at risk for having an ischemic stroke and to optimize their comorbidities preoperatively. Patients with intraoperative ischemic stroke carry a higher risk for morbidity and mortality during the index hospitalization. Level of Evidence: 4
Source: Spine - January 8, 2020 Category: Orthopaedics Tags: CLINICAL CASE SERIES Source Type: research

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