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Condition: Hypertension
Drug: Insulin
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Total 267 results found since Jan 2013.

Association between high sensitivity C-reactive protein and metabolic syndrome in subjects completing the National Health and Nutrition Examination Survey (NHANES) 2009–10
Conclusions Presence of metabolic syndrome was common in subjects from NHANES 2009–10 and a significant “dose-related” association was confirmed between number of metabolic syndrome conditions and increasing odds of elevated hs-CRP concentration.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - October 12, 2014 Category: Endocrinology Source Type: research

Risk factors associated with abnormal cognition in Japanese outpatients with diabetes, hypertension or dyslipidemia
Conclusions Because of the higher prevalence of abnormal cognition in aged outpatients with diabetes found in primary care practice and significant associations with serum albumin, uric acid, renal function, retinopathy and antidiabetic drugs, there is a need for early diagnosis and strategies against dementia.
Source: Diabetology International - November 9, 2014 Category: Endocrinology Source Type: research

Gal-geun-dang-gwi-tang improves diabetic vascular complication in apolipoprotein E KO mice fed a western diet
Conclusions: These findings suggest that GGDGT attenuates endothelial dysfunction via improvement of the nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) signalling pathway and improves insulin sensitivity in diabetic atherosclerosis.
Source: BMC Complementary and Alternative Medicine - November 22, 2014 Category: Complementary Medicine Authors: So LeeYun LeeJung ChoiMin KhoJung YoonSun ShinDae KangHo Lee Source Type: research

Club 35 Poster session 1: Wednesday 3 December 2014, 09:00-16:00 * Location: Poster area
Left ventricle hypertrophy (LVH) is strongly associated with stroke and myocardial infarction in hypertensive patients. Hypertensive heart characterized by cardiomyocytes hypertrophy, fibroblasts proliferation, enlargement of interstitial collagen volume and their ratio disorders which result in dangerous complications. Renin-angiotensin-aldosterone system (RAAS) and insulin-like growth factor 1 (IGF-1) play significant role in development of myocardial fibrosis and LV remodelling in hypertensive patients. The purpose of the study is to evaluate relations between activity of RAAS and interstitial fibrosis markers and left ...
Source: European Heart Journal Cardiovascular Imaging - December 5, 2014 Category: Radiology Authors: Krestjyaninov, M., Gimaev, R., Razin, V., Halaph, H., Shameeva, O., Galli, E., Oger, E., Levery, M., Mabo, P., Donal, E., Rodriguez Munoz, D., Carbonell Sanroman, A., Moya Mur, J., Lazaro Rivera, C., Fernandez Santos, S., Rincon Diaz, L., Casas Rojo, E., Tags: Wednesday 13 December 2014 Source Type: research

Making one change — getting more fiber — can help with weight loss
Getting to a healthy weight and staying there is an important way to prevent heart disease, diabetes, some cancers, and other serious conditions. Many of us know firsthand just how hard it can be to reach and maintain that healthy weight. And there’s no shortage of ways to try to get there: You can count calories, carbs, or points. You can cut back on fat or sugar. You can try any number of popular diets that forbid certain foods, or focus on just one (the grapefruit diet, anyone?). Any of these approaches might work for you. Or they might not — in large part because they are complicated. A study published in todayR...
Source: New Harvard Health Information - February 17, 2015 Category: Consumer Health News Authors: Nancy Ferrari Tags: Diet and Weight Loss Healthy Eating fiber Source Type: news

7 Ways to Permanently Banish Belly Fat
Sixty-nine percent of Americans adults are overweight, and over 35 percent are obese. Obesity increases your risk for numerous conditions including heart disease, stroke, Type 2 diabetes, high blood pressure, and cancer. Sadly, about 3.4 million adults die each year from being overweight or obese. Globally obesity now kills about the same as tobacco and all wars, terrorism and violence. Nearly all people who are overweight already have "pre-diabetes" and have significant risks of disease and death. They just don't know it. When you begin to put on weight, especially lethal belly fat, your biology shifts out of balance, v...
Source: Healthy Living - The Huffington Post - February 27, 2015 Category: Consumer Health News Source Type: news

Carotid Intima-Media Thickness Is Associated With the Progression of Cognitive Impairment in Older Adults Clinical Sciences
Conclusions— Greater baseline CIMT was independently associated with the risk of cognitive impairment, such as MCI and dementia in elderly subjects.
Source: Stroke - March 23, 2015 Category: Neurology Authors: Moon, J. H., Lim, S., Han, J. W., Kim, K. M., Choi, S. H., Park, K. S., Kim, K. W., Jang, H. C. Tags: Carotid Stenosis Clinical Sciences Source Type: research

Preclinical and clinical evidence for the role of resveratrol in the treatment of cardiovascular diseases
This article is part of a Special Issue entitled: Resveratrol: Challenges in translating pre-clinical findings to improved patient outcomes.
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - April 3, 2015 Category: Molecular Biology Source Type: research

Catching Dick: Not Why We Care About Weight
Amy Schumer said in her humorous acceptance speech at the Glamour Women of the Year Awards: "I'm like 160 pounds right now, and I can catch a dick whenever I want, and that's the truth." The line, like many in her speech, is obviously very funny. But the humor is directed at a misperception that is not so funny. With our society's superficial focus on youth and appearance, we have emphasized all the wrong reasons for maintaining a healthy body weight, which has nothing to do with "catching dick." We are sold the idea that remaining slim is primarily important as a means of attracting the opposite sex, rather than as a pa...
Source: Science - The Huffington Post - June 4, 2015 Category: Science Source Type: news

What have we learned about GPER function in physiology and disease from knockout mice?
Publication date: Available online 16 July 2015 Source:The Journal of Steroid Biochemistry and Molecular Biology Author(s): Eric R. Prossnitz, Helen J. Hathaway Estrogens, predominantly 17β-estradiol, exert diverse effects throughout the body in both normal and patho-physiology, during development and in reproductive, metabolic, endocrine, cardiovascular, nervous, musculoskeletal and immune systems. Estrogen and its receptors also play important roles in carcinogenesis and therapy, particularly for breast cancer. In addition to the classical nuclear estrogen receptors (ERα and ERβ) that traditionally mediate predomi...
Source: The Journal of Steroid Biochemistry and Molecular Biology - July 17, 2015 Category: Biochemistry Source Type: research

Heartbeat: Highlights from this issue
Prevention of atrial fibrillation (AF) is an urgent unmet clinical need given its association with a higher risk of stroke, heart failure and death. Known risk factors for AF include age, hypertension, body mass index and diabetes as well as markers of systemic inflammation; all of which likely contribute to the high prevalence of this dysrhythmia in our aging, increasingly obese, population. However, there currently are no established biomarkers to help in assessment of AF risk. Adiponectin is an adipocyte-generated hormone with lower levels seen with increased adiposity. Adiponectin has insulin sensitizing, anti-inflamma...
Source: Heart - August 12, 2015 Category: Cardiology Authors: Otto, C. M. Tags: Drugs: cardiovascular system, Hypertension, Epidemiology, Tobacco use Heartbeat Source Type: research

Plasma Levels of Soluble IL-2 Receptor α: Associations With Clinical Cardiovascular Events and Genome-Wide Association Scan.
CONCLUSIONS: These results support a role for sIL-2Rα in atherosclerosis and provide evidence for multiple-associated single-nucleotide polymorphisms at chromosome 10p15-14. PMID: 26293465 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - August 20, 2015 Category: Cardiology Authors: Durda P, Sabourin J, Lange EM, Nalls MA, Mychaleckyj JC, Jenny NS, Li J, Walston J, Harris TB, Psaty BM, Valdar W, Liu Y, Cushman M, Reiner AP, Tracy RP, Lange LA Tags: Arterioscler Thromb Vasc Biol Source Type: research

Microvascular complications and prevalence of urgency incontinence in Japanese patients with type 2 diabetes mellitus: The dogo study
ConclusionsIn Japanese patients with type 2 diabetes mellitus, only diabetic neuropathy was independently positively associated with urgency incontinence. Neurourol. Urodynam. © 2015 Wiley Periodicals, Inc.
Source: Neurourology and Urodynamics - September 9, 2015 Category: Urology & Nephrology Authors: Shinya Furukawa, Takenori Sakai, Tetsuji Niiya, Hiroaki Miyaoka, Teruki Miyake, Shin Yamamoto, Koutatsu Maruyama, Teruhisa Ueda, Hidenori Senba, Yasuhiko Todo, Masamoto Torisu, Hisaka Minami, Morikazu Onji, Takeshi Tanigawa, Bunzo Matsuura, Yoichi Hiasa, Tags: Original Clinical Article Source Type: research

Identifying and Describing the Impact of Cyclone, Storm and Flood Related Disasters on Treatment Management, Care and Exacerbations of Non-communicable Diseases and the Implications for Public Health
Conclusion Cyclone, flood and storm related disasters impact on treatment management and overall care for people with NCDs. This results in an increased risk of exacerbation of illness or even death. The interruption may be caused by a range of factors, such as damaged transport routes, reduced health services, loss of power and evacuations. The health impact varies according to the NCD. For people with chronic respiratory diseases, a disaster increases the risk of acute exacerbation. Meanwhile, for people with cancer, cardiovascular diseases and diabetes there is an increased risk of their illness exacerbating, which can ...
Source: PLOS Currents Disasters - September 28, 2015 Category: Global & Universal Authors: jc164421 Source Type: research

Association of whole blood viscosity with non-alcoholic fatty liver disease.
CONCLUSIONS: The findings showed that WBV at low shear stress is increased in NAFLD. Moreover, WBV at low shear stress is independently associated with NAFLD even after adjusting other cardiovascular risk factors. PMID: 26444605 [PubMed - as supplied by publisher]
Source: Clinical Hemorheology and Microcirculation - September 25, 2015 Category: Hematology Authors: Yu XY, Li Y, Liu T, Wang RT Tags: Clin Hemorheol Microcirc Source Type: research