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Specialty: Cardiology
Condition: Hemorrhagic Stroke

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Total 1473 results found since Jan 2013.

Extracranial carotid plaque hemorrhage predicts ipsilateral stroke recurrence in patients with carotid atherosclerosis - a study based on high-resolution vessel wall imaging MRI
CONCLUSIONS: Carotid intraplaque hemorrhage is strongly associated with recurrent ischemic events and could predict recurrent ipsilateral stroke.PMID:35764942 | DOI:10.1186/s12883-022-02758-3
Source: Atherosclerosis - June 28, 2022 Category: Cardiology Authors: Fengli Che Donghua Mi Anxin Wang Yi Ju Binbin Sui Xiaokun Geng Xihai Zhao Xingquan Zhao Source Type: research

Dual vs. mono antiplatelet therapy for acute ischemic stroke or transient ischemic attack with evidence of large artery atherosclerosis
CONCLUSION: In patients with symptomatic large artery extracranial or intracranial atherosclerosis, DAPT was superior to MAPT in preventing IS recurrence without increasing bleeding risks. The optimal DAPT regimens and duration of treatment in this population need to be clarified in further studies.PMID:36172029 | PMC:PMC9510375 | DOI:10.3389/fneur.2022.923142
Source: Atherosclerosis - September 29, 2022 Category: Cardiology Authors: Chun-Jen Lin Tzu-Yun Tseng Jeffrey L Saver Source Type: research

Carotid Plaque Characteristics Predict Recurrent Ischemic Stroke and TIA: The PARISK (Plaque At RISK) Study
CONCLUSIONS: IPH and total plaque volume are independent risk factors for recurrent ipsilateral ischemic stroke or TIA in patients with mild-to-moderate carotid stenosis. These plaque characteristics improve current decision making. Validation studies to implement plaque characteristics in clinical scoring tools are needed. (PARISK: Validation of Imaging Techniques [PARISK]; NCT01208025).PMID:36202450 | DOI:10.1016/j.jcmg.2022.04.003
Source: Atherosclerosis - October 6, 2022 Category: Cardiology Authors: Dianne H K van Dam-Nolen Martine T B Truijman Anja G van der Kolk Madieke I Liem Floris H B M Schreuder Eric Boersma Mat J A P Daemen Werner H Mess Robert J van Oostenbrugge Antonius F W van der Steen Daniel Bos Peter J Koudstaal Paul J Nederkoorn Jeroen Source Type: research

Abstract 217: How well does the CHADS2 Stroke Risk Score Predict Major Hemorrhage in Patients with Atrial Fibrillation? Poster Session II
Conclusions: Although some clinical markers of stroke risk such as those included in the CHADS2 risk score are also associated with increased hemorrhage risk, the CHADS2 risk score should not be used instead of a validated hemorrhage risk tool to estimate hemorrhage risk.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Quinn, G. R., Singer, D. E., Go, A. S., Chang, Y., Borowsky, L., Pomernacki, N., Udaltsova, N., Fang, M. C. Tags: Poster Session II Source Type: research

Net Clinical Benefit of Warfarin Therapy in Elderly Chinese Patients With Atrial Fibrillation Original Articles
Conclusions— In elderly patients with atrial fibrillation, warfarin therapy is associated with lower death and ischemic stroke and an overall net clinical benefit.
Source: Circulation: Arrhythmia and Electrophysiology - April 15, 2014 Category: Cardiology Authors: Siu, C.-W., Tse, H.-F. Tags: Cerebrovascular disease/stroke, Arrhythmias, clinical electrophysiology, drugs, Anticoagulants Original Articles Source Type: research

Efficacy and safety of apixaban compared with warfarin according to age for stroke prevention in atrial fibrillation: observations from the ARISTOTLE trial
Conclusion The benefits of apixaban vs. warfarin were consistent in patients with AF regardless of age. Owing to the higher risk at older age, the absolute benefits of apixaban were greater in the elderly.
Source: European Heart Journal - July 21, 2014 Category: Cardiology Authors: Halvorsen, S., Atar, D., Yang, H., De Caterina, R., Erol, C., Garcia, D., Granger, C. B., Hanna, M., Held, C., Husted, S., Hylek, E. M., Jansky, P., Lopes, R. D., Ruzyllo, W., Thomas, L., Wallentin, L. Tags: Atrial fibrillation Source Type: research

Consciousness Level and Off-Hour Admission Affect Discharge Outcome of Acute Stroke Patients: A J-ASPECT Study Health Services and Outcomes Research
Conclusions The well-known off-hour effect might be attributed to the severely ill patient population. Thus, sustained stroke care that is sufficient to treat severely ill patients during off-hours is important.
Source: JAHA:Journal of the American Heart Association - October 21, 2014 Category: Cardiology Authors: Kamitani, S., Nishimura, K., Nakamura, F., Kada, A., Nakagawara, J., Toyoda, K., Ogasawara, K., Ono, J., Shiokawa, Y., Aruga, T., Miyachi, S., Nagata, I., Matsuda, S., Miyamoto, Y., Iwata, M., Suzuki, A., Ishikawa, K. B., Kataoka, H., Morita, K., Kobayash Tags: Health Services and Outcomes Research Source Type: research

Efficacy of nafamostat mesilate as anticoagulation during cardiopulmonary bypass for early surgery in patients with active infective endocarditis complicated by stroke.
CONCLUSION: Nafamostat mesilate, administered in conjunction with low-dose heparinization, served as an effective anticoagulant for early surgery in patients with AIE complicated by stroke, and caused no further deterioration of the cerebral lesions. PMID: 25790622 [PubMed - in process]
Source: Journal of Heart Valve Disease - March 21, 2015 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Dual Antiplatelet Therapy in Acute Ischemic Stroke
Abstract Stroke recurrence is common in the early period after a cerebral ischemic event. Treatment with an antiplatelet agent is recommended to reduce recurrent stroke and death in patients with a non-cardioembolic ischemic stroke and transient ischemic attack. Compared to monotherapy, dual antiplatelet therapy has more robust inhibition of platelet activation but a higher risk of systemic bleeding and intracranial hemorrhage. Randomized controlled trials and meta-analyses suggest that short-term use of dual antiplatelet treatment initiated early after ischemic stroke and TIA reduces the risk of recurrent stroke...
Source: Current Atherosclerosis Reports - May 20, 2015 Category: Cardiology Source Type: research

Effects of candesartan in acute stroke on activities of daily living and level of care at 6 months
Conclusion: Blood pressure-lowering treatment with candesartan had no beneficial effect on activities of daily living and level of care at 6 months. This result is compatible with the results of the main analysis of the modified Rankin scale, and supports the conclusion that there is no indication for routine blood pressure treatment with candesartan in the acute phase of stroke.
Source: Journal of Hypertension - June 5, 2015 Category: Cardiology Tags: ORIGINAL PAPERS: Therapeutic aspects Source Type: research

Left Atrial Appendage Closure as an Alternative to Warfarin for Stroke Prevention in Atrial Fibrillation A Patient-Level Meta-Analysis
ConclusionsIn patients with NVAF at increased risk for stroke or bleeding who are candidates for chronic anticoagulation, LAAC resulted in improved rates of hemorrhagic stroke, cardiovascular/unexplained death, and nonprocedural bleeding compared to warfarin.
Source: Journal of the American College of Cardiology - June 15, 2015 Category: Cardiology Source Type: research

Intracranial Hemorrhage After Ischemic Stroke: Incidence, Time Trends, and Predictors in a Swedish Nationwide Cohort of 196 765 Patients Original Articles
Conclusions— The incidence of ICrH within 1 year after ischemic stroke was 2% per year at risk, about 15 times higher compared with the reference population. Over the study period, ICrH risk increased within the first 30 days but decreased thereafter. Previous ICrH, thrombolysis, and male sex affected the risk, whereas an increased use of antithrombotic treatments and statins did not.
Source: Circulation: Cardiovascular Quality and Outcomes - July 21, 2015 Category: Cardiology Authors: Ogren, J., Irewall, A.-L., Bergstrom, L., Mooe, T. Tags: Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Epidemiology Original Articles Source Type: research

Risk of Recurrent Neurologic Stroke or Transient Ischemic Attack in Patients with Cryptogenic Stroke and Intrapulmonary Shunt
ConclusionsPatients with IPS and cryptogenic stroke or TIA did not have a higher recurrence of ischemic cerebral events. Warfarin was significantly higher at follow‐up in the IPS compared to the non‐IPS group, which may explain these findings. A study randomizing patients with IPS and cryptogenic stroke or TIA to warfarin or no warfarin would be of great interest.
Source: Echocardiography - July 22, 2015 Category: Cardiology Authors: Rahul S. Sinha, Zeeshan Hussain, Nirmanmoh Bhatia, Marcus F. Stoddard Tags: Original Investigation Source Type: research

Patient-Centered Decision Support in Acute Ischemic Stroke: Qualitative Study of Patients' and Providers' Perspectives Original Articles
Conclusions— This study suggests that a positively framed risk–benefit tool with graphical presentations of general and patient-specific risk estimates could support patients and providers in considering r-tPA for acute ischemic stroke. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01864928.
Source: Circulation: Cardiovascular Quality and Outcomes - October 29, 2015 Category: Cardiology Authors: Decker, C., Chhatriwalla, E., Gialde, E., Garavalia, B., Summers, D., Quinlan, M. E., Cheng, E., Rymer, M., Saver, J. L., Chen, E., Kent, D. M., Spertus, J. A. Tags: Cardiopulmonary Resuscitation and Emergency Cardiac Care Original Articles Source Type: research

Mechanical Thrombectomy for Acute Ischemic Stroke A Meta-Analysis of Randomized Trials
This study systematically determined if mechanical thrombectomy after usual care would be associated with better outcomes in patients with acute ischemic stroke caused by large artery occlusion.MethodsThe authors included randomized trials that compared mechanical thrombectomy after usual care versus usual care alone for acute ischemic stroke. Random effects summary risk ratios (RR) were constructed using a DerSimonian and Laird model.ResultsNine trials with 2,410 patients were available for analysis. Compared with usual care alone, mechanical thrombectomy was associated with a higher incidence of achieving good functional...
Source: Journal of the American College of Cardiology - November 30, 2015 Category: Cardiology Source Type: research