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Condition: Ischemic Stroke
Therapy: Thrombolytic Therapy

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Total 959 results found since Jan 2013.

Neurophysiology tools to lower the stroke onset to treatment time during the golden hour: microwaves, bioelectrical impedance and near infrared spectroscopy
Ann Med. 2022 Dec;54(1):2658-2671. doi: 10.1080/07853890.2022.2124448.ABSTRACTReperfusion therapy administration timing in acute ischaemic stroke is the main determinant of patients' mortality and long-term disability. Indeed, the first hour from the stroke onset is defined the "golden hour", in which the treatment has the highest efficacy and lowest side effects. Delayed ambulance transport, inappropriate triage and difficulty in accessing CT scans lead to delayed onset to treatment time (OTT) in clinical practice. To date brain CT scan is needed to rule out intracranial haemorrhage, which is a major contraindication to t...
Source: Annals of Medicine - September 26, 2022 Category: Internal Medicine Authors: Lazzaro di Biase Adriano Bonura Maria Letizia Caminiti Pasquale Maria Pecoraro Vincenzo Di Lazzaro Source Type: research

The usefulness of the kurashiki prehospital stroke scale in identifying thrombolytic candidates in acute ischemic stroke.
Conclusion: The KPSS is an effective prehospital stroke scale for identifying candidates for IV-tPA and IA-UK, as indicated by excellent correlation with the NIHSS, in the assessment of stroke severity in acute ischemic stroke. PMID: 24532511 [PubMed - in process]
Source: Yonsei Medical Journal - February 19, 2014 Category: Universities & Medical Training Authors: Jang J, Chung SP, Park I, You JS, Lee HS, Park JW, Chung TN, Chung HS, Lee HS Tags: Yonsei Med J Source Type: research

Code stroke: A mismatch between number of activation and number of thrombolysis.
CONCLUSION: The majority of code stroke patients were stroke patients; however, most of them could not be treated with thrombolytic therapy. These findings underscore the need for further support from the BNHI in order for health-care providers to implement the code stroke systems successfully. PMID: 24961186 [PubMed - in process]
Source: J Formos Med Assoc - June 28, 2014 Category: Journals (General) Authors: Sung SF, Tseng MC Tags: J Formos Med Assoc Source Type: research

The Relationships Among Regionalization, Processes, and Outcomes for Stroke Care: A Nationwide Population-based Study
We examined the association of regionalization with processes and outcomes, and the mediating effect of processes of care on the association between regionalization and mortality for acute stroke in Taiwan. We analyzed all 229,568 admissions with acute ischemic stroke from January 2004 to September 2012 through Taiwan's National Health Insurance Research Database. Regionalized care for acute stroke has been implemented since July 2009 in Taiwan. Rates of thrombolytic therapy within 3 hours after onset of ischemic stroke, average numbers of processes of care, and 30-day mortality rates at monthly intervals for baseline...
Source: Medicine - April 1, 2016 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

World Stroke Day in Taiwan: Raising Public Awareness of Stroke
Conclusion When preparing for future WSD campaigns, the organizing committee must perform a detailed assessment to understand target population requirements and design more appropriate events. For promoting the WSD campaigns, proficient advertising is necessary for attracting attendees and increasing their willingness to participate.
Source: International Journal of Gerontology - August 5, 2016 Category: Geriatrics Source Type: research

Impact of code stroke on thrombolytic therapy in patients with acute ischemic stroke at a secondary referral hospital in Taiwan
ConclusionCode stroke is effective in reducing in-hospital delays. The accuracy of code stroke activation has acceptable sensitivity but low specificity. Rapid patient assessment by neurologists increases the number of patients eligible for thrombolytic therapy.
Source: Journal of the Chinese Medical Association - September 7, 2018 Category: General Medicine Source Type: research

Timing of Initiation of Oral Anticoagulation after Acute Ischemic Stroke in Patients with Atrial Fibrillation
AbstractPatients with atrial fibrillation (AF) who suffer an acute ischemic stroke are at risk for both hemorrhagic transformation and recurrent ischemic stroke in the acute post ‐stroke period. Oral anticoagulants are recommended for secondary stroke prevention in patients with AF. The optimal time to initiate anticoagulant therapy after acute ischemic stroke in patients with AF is uncertain. There is concern that early initiation increases the risk of hemorrhagic transfo rmation, whereas delayed initiation leaves the patient at risk for recurrent ischemic stroke. In this article, we provide a review of the risk of hemo...
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - November 6, 2019 Category: Drugs & Pharmacology Authors: Maureen A. Smythe, Dennis Parker, Candice L. Garwood, Adam Cuker, Steve R. Mess é Tags: REVIEW OF THERAPEUTICS Source Type: research

Tube feeding predictors after ischemic hemispheric stroke during hospitalization
CONCLUSION: Tube feeding during patients hospitalization after ischemic hemispheric stroke was predicted by the severity of stroke and signs of airway permeation.Key pointsSwallowing difficulty is one of the most common post-stroke consequences.There are few studies on the characterization of post-stroke patients with tube feeding.Tube feeding after ischemic stroke predictors were severity of stroke and signs of airway permeation.PMID:33775213 | DOI:10.1080/14015439.2021.1899279
Source: Logopedics, Phoniatrics, Vocology. - March 29, 2021 Category: Speech-Language Pathology Authors: Mar ília Fernandes Carollo Tyalla Duarte Patr ício Cristiane Gon çalves Montibeller Karen Fontes Luchesi Source Type: research

Type of anaesthesia for acute ischaemic stroke endovascular treatment
CONCLUSIONS: In early outcomes, general anaesthesia improves target artery revascularisation compared to non-general anaesthesia with moderate-certainty evidence. General anaesthesia may improve adverse events (haemodynamic instability) compared to non-general anaesthesia with low-certainty evidence. We found no evidence of a difference in neurological impairment, stroke-related mortality, all intracranial haemorrhage and haemodynamic instability adverse events between groups with low-certainty evidence. We are uncertain whether general anaesthesia improves functional outcomes and time to revascularisation because the cert...
Source: Cochrane Database of Systematic Reviews - July 20, 2022 Category: General Medicine Authors: Renato Tosello Rachel Riera Giuliano Tosello Caroline Nb Clezar Jorge E Amorim Vladimir Vasconcelos Benedito B Joao Ronald Lg Flumignan Source Type: research

Improved performance of new prenotification criteria for acute stroke patients.
CONCLUSION: The accuracy of the new prehospital stroke criteria has higher PPV and specificity compared to previous CPSS validation studies. PMID: 25886861 [PubMed - as supplied by publisher]
Source: J Formos Med Assoc - April 15, 2015 Category: Journals (General) Authors: Hsieh MJ, Tang SC, Ko PC, Chiang WC, Tsai LK, Chang AM, Wang AY, Yeh SJ, Huang KY, Jeng JS, Ma MH Tags: J Formos Med Assoc Source Type: research

Risk Factors for In-Hospital Mortality among Ischemic Stroke Patients in Southern Taiwan
Conclusion Nearly 30% of in-hospital mortality is associated with preventable factors. The prognosis of acute stroke can be improved by increased focus on reducing serious complications after stroke, particularly on the prevention of infection, heart disease, and increased intracranial pressure.
Source: International Journal of Gerontology - June 7, 2016 Category: Geriatrics Source Type: research

Inflammatory Disequilibrium in Stroke.
Abstract Over the past several decades, there have been substantial advances in our knowledge of the pathophysiology of stroke. Understanding the benefits of timely reperfusion has led to the development of thrombolytic therapy as the cornerstone of current management of ischemic stroke, but there remains much to be learned about mechanisms of neuronal ischemic and reperfusion injury and associated inflammation. For ischemic stroke, novel therapeutic targets have continued to remain elusive. When considering modern molecular biological techniques, advanced translational stroke models, and clinical studies, a consi...
Source: Circulation Research - June 23, 2016 Category: Cardiology Authors: Petrovic-Djergovic D, Goonewardena SN, Pinsky DJ Tags: Circ Res Source Type: research