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Condition: Sleep Disorders
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Total 18 results found since Jan 2013.

Sex Differences in Sex Hormone Profiles and Prediction of Consciousness Recovery After Severe Traumatic Brain Injury
Conclusion: These findings indicate that TBI differentially affects the levels of sex-steroid hormones in men and women patients. Plasma levels of testosterone could be a good candidate blood marker to predict recovery from unconsciousness after sTBI for male patients. Introduction Traumatic brain injury (TBI) is a major cause of death and disability worldwide and is increasing in incidence (1). Patients with acute severe TBI (sTBI) often develop severe disorders of consciousness, i.e., coma, minimally conscious state or vegetative state. Although many patients may regain consciousness during the 1-month post-TBI p...
Source: Frontiers in Endocrinology - April 25, 2019 Category: Endocrinology Source Type: research

Clinical and Economic Benefits of Upper Airway Stimulation for Obstructive Sleep Apnea in a European Setting
Conclusions: In the present model-based analysis, UAS therapy provides meaningful benefit to patient-relevant endpoints and is a cost-effective therapy in the German setting.Respiration
Source: Respiration - March 31, 2019 Category: Respiratory Medicine Source Type: research

Patient Perspectives on the Therapeutic Profile of Botulinum Neurotoxin Type A in Spasticity
Conclusions: Patients with spasticity can expect a characteristic profile of BoNT-A effects, namely time lag to onset and peak effect followed by a gradual decline in the symptomatic benefits. Symptom re-emergence is common and has significant impact on quality of life. Greater patient/clinician awareness of this therapeutic profile should lead to better level of overall satisfaction with treatment, informed therapeutic discussions and treatment schedule planning.
Source: Frontiers in Neurology - May 6, 2020 Category: Neurology Source Type: research

Association of Long-Term Exposure to Transportation Noise and Traffic-Related Air Pollution with the Incidence of Diabetes: A Prospective Cohort Study
Conclusion: We found a positive association between residential transportation noise and diabetes, adding to the growing body of evidence that noise pollution exposure may be independently linked to metabolic health and should be considered when developing public health interventions. https://doi.org/10.1289/EHP1279 Received: 26 October 2016 Revised: 07 May 2017 Accepted: 09 May 2017 Published: 31 August 2017 Address correspondence to C. Clark, Ove Arup and Partners, Acoustics, 13 Fitzroy Street, London, W1T 4BQ, UK. Telephone: +44 207755 4702. Email: Charlotte.Clark@arup.com The authors declare they have no actual o...
Source: EHP Research - August 31, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

How Loud Noise Exposure Is Linked to Heart Disease
If you live near an airport, railroad tracks or a busy road, you might be concerned about how fumes from those planes, trains and automobiles are affecting your health. But according to a new review in the Journal of the American College of Cardiology, there may be another threat to worry about: high levels of noise that may be bad for your heart. A connection between noise pollution and cardiovascular disease has been observed in numerous studies over the years, the authors of the new review said. High decibel levels from road traffic and airplanes, for example, has been linked to high blood pressure, coronary artery dise...
Source: TIME: Health - February 6, 2018 Category: Consumer Health News Authors: Amanda MacMillan Tags: Uncategorized are loud noises unhealthy healthytime Heart Disease heart disease risks heart health Journal of the American College of Cardiology noise level meter noise meter noise pollution noise-cancelling headphones onetime Rese Source Type: news

Fast Intracortical Sensory-Motor Integration: A Window Into the Pathophysiology of Parkinson ’s Disease
Conclusion and Outlook In this review, we have discussed the possible contributions of the fast-afferent somatosensory pathway, the intracortical integrative component and the fast-efferent corticomotor pathway to alterations of SAI in PD. We concluded that PD-related changes in SAI are most likely caused at the cortical level, where sensory input is rapidly integrated into a motor output. This makes SAI a useful tool to probe how PD impacts on the sensorimotor integration processing at the cortical level. Studies performed on PD patients have shown variable results, ranging from reduced to normal or even enhanced SAI fi...
Source: Frontiers in Human Neuroscience - April 7, 2019 Category: Neuroscience Source Type: research

Orexin-A Prevents Lipopolysaccharide-Induced Neuroinflammation at the Level of the Intestinal Barrier
We examined a possible protective effect of OX-A against LPS-induced ROS formation and microglia activation. To mimic in vitro the connection between gut and brain and to study the putative effect on the cortical microglia, we used a co-culture of Caco-2 cells and primary cortical microglia with Caco-2 cells placed at the apical side of a transwell and primary cortical microglia at the basolateral side. All treatments used to study the apical vs. basal connection were applied to the apical compartment. We used DHR (10 μM, 20 min), a cell-permeable fluorogenic probe useful for the detection of ROS formation, to dete...
Source: Frontiers in Endocrinology - April 9, 2019 Category: Endocrinology Source Type: research

Dynamic Office Environments Improve Brain Activity and Attentional Performance Mediated by Increased Motor Activity
Conclusion The results of the present study reveal short- and mid-term effects on attentional and vigilance performance, and EEG brain activity when working in a dynamic versus a static environment. During working in a dynamic office, attentional and vigilance performance increased compared to working in a static office. Brain activities show increased alpha, beta and gamma power in the frontal and central areas in the attentional task with increased theta, alpha, and beta activity in the vigilance task. These findings suggest that working in a dynamic office environment stimulates the brain towards an optimum psychophysi...
Source: Frontiers in Human Neuroscience - April 11, 2019 Category: Neuroscience Source Type: research

Modulating Applied Task Performance via Transcranial Electrical Stimulation
Conclusion tES may prove valuable for modulating applied task performance, though research in this area warrants careful consideration of several individual-, context-, and task-related factors that may predict the robustness and directionality of tES effects. Whereas most applied research with tES has administered tDCS, tACS and tRNS have also shown potential to modulate cortical activity and behavior. Even in highly applied and dynamic tasks, such as navigation and driving, tES appears to carry some performance benefits. This is compelling because as tES is slowly incorporated into highly complex real-world environments...
Source: Frontiers in Human Neuroscience - April 29, 2019 Category: Neuroscience Source Type: research

How You Should Spend That Extra Hour As Daylight Saving Time Ends
(CNN) — It’s Sunday morning, and you open your eyes to discover it’s still incredibly early because — huzzah! — we’ve reached the end of the seasonal practice known as Daylight Saving Time. Do you: A) Immediately roll over and go back to sleep? or B) Tell yourself that you shouldn’t be lazy, and get up to make the most of this “extra” hour? It’s a trick question, because there isn’t a perfectly right answer that would be the same for everyone. But in general, experts say, most should use the fall time change to squeeze in more sleep — and with zero gu...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - October 31, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Offbeat CNN Daylight saving time Source Type: news

How to Keep Alzheimer ’s From Bringing About the Zombie Apocalypse
I tried to kill my father for years. To be fair, I was following his wishes. He’d made it clear that when he no longer recognized me, when he could no longer talk, when the nurses started treating him like a toddler, he didn’t want to live any longer. My father was 58 years old when he was diagnosed with Alzheimer’s disease. He took the diagnosis with the self-deprecating humor he’d spent a lifetime cultivating, constantly cracking jokes about how he would one day turn into a zombie, a walking corpse. We had a good 10 years with him after the diagnosis. Eventually, his jokes came true. Seven years ...
Source: TIME: Health - November 20, 2019 Category: Consumer Health News Authors: Jay Newton-Small Tags: Uncategorized Alzheimer's Disease Source Type: news

How our brains create breathing rhythm is unique to every breath
Breathing propels everything we do, so its rhythm must be carefully organized by our brain cells, right?Wrong.Every breath we take arises from a disorderly group of neurons — each one like a soloist belting out its song before it unites with other neurons to harmonize on a fresh breath.That ’s the gist ofa UCLA study published March 3 in the online edition of  Neuron.“We were surprised to learn that how our brain cells work together to generate breathing rhythm is different every time we take a breath,” saidJack Feldman, the study ’s senior author, a professor of neurobiology at the David Geffen School of Medic...
Source: UCLA Newsroom: Health Sciences - March 4, 2020 Category: Universities & Medical Training Source Type: news

Artificial Intelligence Is Here To Calm Your Road Rage
I am behind the wheel of a Nissan Leaf, circling a parking lot, trying not to let the day’s nagging worries and checklists distract me to the point of imperiling pedestrians. Like all drivers, I am unwittingly communicating my stress to this vehicle in countless subtle ways: the strength of my grip on the steering wheel, the slight expansion of my back against the seat as I breathe, the things I mutter to myself as I pilot around cars and distracted pedestrians checking their phones in the parking lot. “Hello, Corinne,” a calm voice says from the audio system. “What’s stressing you out right n...
Source: TIME: Science - August 26, 2020 Category: Science Authors: Corinne Purtill Tags: Uncategorized Source Type: news