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Agreement between self-reported diseases from health surveys and national health registry data: a Danish nationwide study
Conclusion Overall, self-reported data were accurate in identifying individuals without the specific disease (ie, specificity and NPV). However, sensitivity, PPV and kappa varied greatly between diseases. These findings should be considered when interpreting similar results from surveys.
Source: Journal of Epidemiology and Community Health - January 10, 2023 Category: Epidemiology Authors: Jensen, H. A. R., Lau, C. J., Davidsen, M., Ekholm, O., Christensen, A. I. Tags: Original research Source Type: research

Factors Associated With the Development of Tinnitus and With the Degree of Annoyance Caused by Newly Developed Tinnitus
Objectives: Tinnitus is highly prevalent, but only a few risk factors for developing tinnitus are known and little is known about factors associated with the degree of annoyance of new-onset tinnitus. Longitudinal analysis can reveal risk factors associated with the development of tinnitus and might lead to targeted prevention. The aim of this study is twofold. (1) To identify risk factors that are longitudinally associated with the odds of developing tinnitus 5 years later. (2) To identify factors that are cross-sectionally associated with tinnitus annoyance in adults with new-onset tinnitus. Methods: Baseline,...
Source: Ear and Hearing - October 28, 2022 Category: Audiology Tags: Research Article Source Type: research

Self-report of chronic diseases in old-aged individuals: extent of agreement with general practitioner medical records in the German AugUR study
Conclusion Self-reports may be an effective tool to assess diabetes and cancer in observational studies in the old and very old aged. In contrast, self-reports on heart failure, musculoskeletal, kidney or lung diseases may be substantially imprecise.
Source: Journal of Epidemiology and Community Health - October 10, 2022 Category: Epidemiology Authors: Steinkirchner, A. B., Zimmermann, M. E., Donhauser, F. J., Dietl, A., Brandl, C., Koller, M., Loss, J., Heid, I. M., Stark, K. J. Tags: Open access Original research Source Type: research

Impact of comorbid conditions on health care expenditure and work-related outcomes in patients with rheumatoid arthritis.
CONCLUSION: Comorbid conditions in RA patients were associated with higher annual health care expenditure, lower likelihood of employment, higher rates of absenteeism and lower income. Despite its low prevalence, heart failure was associated with the highest incremental health care expenditure and the lowest likelihood of being employed compared to other common comorbid conditions. PMID: 33323533 [PubMed - as supplied by publisher]
Source: J Rheumatol - December 15, 2020 Category: Rheumatology Authors: Vu M, Carvalho N, Clarke PM, Buchbinder R, Tran-Duy A Tags: J Rheumatol Source Type: research

Prevalence of and Changes in Tooth Loss Among Adults Aged ≥50 Years with Selected Chronic Conditions - United States, 1999-2004 and 2011-2016.
Abstract Extensive tooth loss can lead to poor diet resulting in weight loss or obesity (1). It can also detract from physical appearance and impede speech, factors that can restrict social contact, inhibit intimacy, and lower self-esteem (1). Chronic medical conditions and oral conditions share common risk factors (2). Persons with chronic conditions are more likely to have untreated dental disease, which can result in tooth loss. Three measures of tooth loss during 1999-2004 and 2011-2016 were estimated by comparing data from the National Health and Nutrition Examination Survey (NHANES) for each period among adu...
Source: MMWR Morb Mortal Wkl... - May 28, 2020 Category: Epidemiology Authors: Parker ML, Thornton-Evans G, Wei L, Griffin SO Tags: MMWR Morb Mortal Wkly Rep Source Type: research

Geniposide Alleviates Glucocorticoid-Induced Inhibition of Osteogenic Differentiation in MC3T3-E1 Cells by ERK Pathway
Conclusion In summary, we demonstrated that geniposide alleviated GC-induced osteogenic suppression in MC3T3-E1 cells. The effects of geniposide were at least partially associated with activating ERK signaling pathway via GLP-1 receptor. Geniposide might be a potential therapeutic agent for protection against GC-induced osteoporosis. Author Contributions BX, DX, CZ, and LW participated in research design. BX, JW, YL, XW, and ZZ conducted the experiments. BX, DX, and LW contributed new reagents or analytic tools and wrote or contributed to the writing of the manuscript. BX, JW, CZ, and DX performed the data analysis. Fu...
Source: Frontiers in Pharmacology - April 17, 2019 Category: Drugs & Pharmacology Source Type: research

Plant-Derived Alkaloids: The Promising Disease-Modifying Agents for Inflammatory Bowel Disease
Conclusion This paper summarizes the current findings regarding the anti-colitis activity of plant-derived alkaloids and shows how these alkaloids exhibit significant and beneficial effects in alleviating colonic inflammation. These natural alkaloids are not only promising agents for IBD treatment but are also components for developing new wonder drugs. However, the underlying molecular mechanisms or toxicological evaluation of most plant-derived alkaloids still require much scientific research, and their actual efficacies for IBD patients have not been verified well in field research. Thus, further clinical trials to elu...
Source: Frontiers in Pharmacology - April 11, 2019 Category: Drugs & Pharmacology Source Type: research

Video Education: Patient Outreach Effort Offers Education about Cardiovascular Risks
Experts in rheumatoid arthritis, cardiovascular health and education have joined forces to create a video intervention designed to help patients understand their risks for heart attack and stroke, as well as how to reduce these risks. Early research into this educational intervention shows the video is effective...
Source: The Rheumatologist - June 27, 2018 Category: Rheumatology Authors: Carina Stanton Tags: Conditions Rheumatoid Arthritis cardiovascular Education patient education risk video Source Type: research

New Building At Brigham And Women ’ s Could Revolutionize Health Care
BOSTON (CBS) – Last week WBZ reported on a new innovative building at Brigham and Women’s Hospital. That building opened its doors to patients Monday for the first time and Dr. Mallika Marshall was there to speak to one of those patients and his surgeons who helped make the building a reality. Plymouth’s George Svajian will never forget that one high school football game more than 50 years ago that destroyed his knee. “I went running down the sideline and as soon as put my leg down, the defensive back hit me right here and my knee felt like it went out,” recalls George. After years of crippling pain, Geor...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - October 3, 2016 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health Local News Seen On WBZ-TV Syndicated Local Watch Listen Boston Brigham & Women's Hospital Dr. Mallika Marshall Source Type: news

Prevalence and risk factors of arthritis in a middle-aged and older Chinese population: the China Health and Retirement Longitudinal Study
Conclusion. Middle-aged and older Chinese adults had a high prevalence of arthritis. Cardiovascular disease is a novel risk factor for arthritis in this population.
Source: Rheumatology - March 24, 2015 Category: Rheumatology Authors: Li, C., Liu, T., Sun, W., Wu, L., Zou, Z.-Y. Tags: Rheumatoid Arthritis CLINICAL SCIENCE Source Type: research

Predictors of mortality in patients with rheumatoid arthritis in Lithuania: Data from a cohort study over 10 years.
CONCLUSIONS: Higher age, lower education and cardiovascular comorbidities were identified as predictors of mortality in this prospective cohort study while disease-related variables were not independent predictors of mortality. PMID: 25744772 [PubMed - in process]
Source: Medicina (Kaunas) - March 8, 2015 Category: Universities & Medical Training Authors: Dadonienė J, Stropuvienė S, Stukas R, Venalis A, Sokka-Isler T Tags: Medicina (Kaunas) Source Type: research

Even 'light' smoking may raise women's arthritis risk
Conclusion This research indicates that a relatively low level of smoking (one to seven cigarettes per day) is associated with an increased risk of developing rheumatoid arthritis compared with women who had never smoked. This adds further knowledge to previous research that has suggested that cigarette smoking is directly linked to a higher risk of developing rheumatoid arthritis. While this study is relatively robust and its results believable, it does have limitations that should be considered. It was not clear how many women dropped out of the study. If this was a large proportion of the women who started, it could si...
Source: NHS News Feed - April 23, 2013 Category: Consumer Health News Tags: Cancer Heart/lungs Lifestyle/exercise Source Type: news